Bss119 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Bss119 (Bone structure and strength QTL 119) Rattus norvegicus

Symbol: Bss119
Name: Bone structure and strength QTL 119
RGD ID: 11530002
Trait: lumbar vertebra area   (VT:0010570)    
Measurement Type: lumbar vertebra area   (CMO:0001688)    
LOD Score: 16.39
P Value: 4.0E-17
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21220,873,419 - 21,346,740RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01223,920,656 - 24,394,383RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01225,918,064 - 26,391,686RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41222,000,595 - 22,501,174RGD_MAPPER_PIPELINERGSC3.4
Cross Type: Not Available
Strains Crossed: NAft:HS 



Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bss119Ratabnormal lumbar vertebrae morphology  IAGP 11528619 RGD 

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bss119Ratlumbar vertebra area  IDA 11528619 RGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bss119Ratcontrol condition  IDA 11528619 RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bss119Ratdual-energy x-ray absorptiometry  IDA 11528619 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bss119RatNAft:HS  IEA 11528619 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bss119Ratlumbar vertebra area  IDA 11528619 RGD 


#
Reference Title
Reference Citation
1. Fine mapping of bone structure and strength QTLs in heterogeneous stock rat. Alam I, etal., Bone. 2015 Dec;81:417-26. doi: 10.1016/j.bone.2015.08.013. Epub 2015 Aug 19.


1 to 17 of 17 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1587868Srrm3serine/arginine repetitive matrix 3122080887820878557Rat
11499585LOC108352435uncharacterized LOC108352435122088043520891489Rat
619719Mdh2malate dehydrogenase 2122089426920907225Rat
1305845Styxl1serine/threonine/tyrosine interacting-like 1122090741020940232Rat
1311474Tmem120atransmembrane protein 120A122094224320950908Rat
68335Porcytochrome p450 oxidoreductase122095105820999198Rat
1308231Rhbdd2rhomboid domain containing 2122104360521054305Rat
1310245Ccl24C-C motif chemokine ligand 24122110083521104832Rat
1587817Ccl26C-C motif chemokine ligand 26122110938421114336Rat
1583828Rps13-ps4ribosomal protein S13, pseudogene 4122112530921125763Rat
620305Hip1huntingtin interacting protein 1122113336421267796Rat
41306277LOC120095918uncharacterized LOC120095918122115005021151606Rat
620680Pom121POM121 transmembrane nucleoporin122127371321294299Rat
41275322LOC120095917uncharacterized LOC120095917122127463921276764Rat
1309268Nsun5NOP2/Sun RNA methyltransferase 5122129363721299319Rat
631346Trim50tripartite motif-containing 50122130078421317668Rat
1308926Fkbp6FKBP prolyl isomerase family member 6122131825121390350Rat

1 to 17 of 17 rows
1 to 20 of 28 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
10888D12Wox1089122089438020894469Ratregion
37878D12Rat33239122114617721146418Ratregion
39236D12Rat51213122127306221273283Ratregion
44969D12Got102135122111996721120102Ratregion
44973D12Got103251122087451320874764Ratregion
1629647D12Got220119122088154520881664Ratregion
5034339Fkbp6480122132920421329685Ratregion
5035208BM390639203122089592320896126Ratregion
5031165BE116737176122114569821145874Ratregion
5053073RH142438173122089429520894468Ratregion
5044252RH130496189122129430721294496Ratregion
5048884RH133161208122126428421264492Ratregion
5039492RH127736541122089444920894990Ratregion
5040162RH128125209122126731721267526Ratregion
5040586RH128368216122118577921185995Ratregion
5071224RH134959188122130086021301048Ratregion
5071830RH135309202122117085121171053Ratregion
5072234RH136731142122103984321039985Ratregion
5068616AU047037210122116606721166275Ratregion
5065896AA964673117122126528921265406Ratregion
1 to 20 of 28 rows

Flank 1: (rs197969186)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21220,873,419 - 20,873,419RGD
Rnor_6.01223,920,656 - 23,920,656RGD
Peak: (rs196994347)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21221,030,965 - 21,030,965RGD
Rnor_6.01224,078,608 - 24,078,608RGD
Flank 2: (rs197046678)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21221,346,740 - 21,346,740RGD
Rnor_6.01224,394,383 - 24,394,383RGD


1 to 10 of 55 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
631560Apr1Acute phase response QTL 16.1orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)121914436246669029Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
61324Eae5Experimental allergic encephalomyelitis QTL 514nervous system integrity trait (VT:0010566)percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time (CMO:0001402)121961087046669029Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)12142110980Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)12960327746669029Rat
61331Eau2Experimental allergic uveoretinitis QTL 20.0005uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)12852542328064601Rat
737822Alc10Alcohol consumption QTL 102.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)121961087040218516Rat
2293684Bmd26Bone mineral density QTL 264.40.0002femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)121587265332974238Rat
6893681Bw109Body weight QTL 1092.30.004body mass (VT:0001259)body weight (CMO:0000012)12123297788Rat
1302792Scl21Serum cholesterol level QTL 213.80.0011blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)12719673046669029Rat

1 to 10 of 55 rows


Note Type Note Reference
qtl_general number of animals used: 1524 HS rats (728 male, 796 female) were used. 11528619
qtl_general measurement method: Rats on a standard diet were euthanized at 17 to 20 weeks of age, and lumbar vertebrae (L3-5) were scanned using DXA (PIXImus II mouse densitometer; Lunar Corp., Madison, WI, USA) with ultra-high resolution (0.18x0.18 mm/pixel). 11528619