Gene: Aacs (acetoacetyl-CoA synthetase) Rattus norvegicus
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Symbol: Aacs
Name: acetoacetyl-CoA synthetase
Description: ENCODES a protein that exhibits acetoacetate-CoA ligase activity; butyrate-CoA ligase activity; INVOLVED IN adipose tissue development; cellular response to cholesterol; cellular response to glucose stimulus; PARTICIPATES IN ketone bodies metabolic pathway; butanoate metabolic pathway; ASSOCIATED WITH Experimental Diabetes Mellitus; obesity; FOUND IN cytosol; INTERACTS WITH (S)-nicotine; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: AcAc-CoA ligase; acetoacetate-CoA ligase; acetoacetyl-CoA ligase; LOC65984
Orthologs:
Homo sapiens (human) : AACS (acetoacetyl-CoA synthetase)  HGNC  Alliance
Mus musculus (house mouse) : Aacs (acetoacetyl-CoA synthetase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Aacs (acetoacetyl-CoA synthetase)
Pan paniscus (bonobo/pygmy chimpanzee) : AACS (acetoacetyl-CoA synthetase)
Canis lupus familiaris (dog) : AACS (acetoacetyl-CoA synthetase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aacs (acetoacetyl-CoA synthetase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01236,512,393 - 36,555,694 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01238,381,585 - 38,425,026 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41232,206,863 - 32,250,583 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11232,070,250 - 32,113,971 (-)NCBI
Celera1232,807,686 - 32,851,029 (-)NCBICelera
Cytogenetic Map12q14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Aacs
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 708522
Created: 2003-09-23
Species: Rattus norvegicus
Last Modified: 2018-01-30
Status: ACTIVE