Fry (FRY microtubule binding protein) - Rat Genome Database
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Gene: Fry (FRY microtubule binding protein) Rattus norvegicus
Analyze
Symbol: Fry
Name: FRY microtubule binding protein
RGD ID: 1307034
Description: Predicted to have enzyme inhibitor activity. Predicted to be involved in cell morphogenesis; negative regulation of tubulin deacetylation; and neuron projection development. Predicted to localize to cell cortex and site of polarized growth. Orthologous to human FRY (FRY microtubule binding protein); INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; acetamide; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: furry homolog; furry homolog (Drosophila); LOC304244; RGD1307034; similar to hypothetical protein CG003
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2124,493,890 - 4,887,118 (-)NCBI
Rnor_6.0 Ensembl125,573,729 - 5,822,874 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0125,573,729 - 5,822,874 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0127,683,059 - 7,925,464 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4124,886,882 - 5,135,963 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1124,888,109 - 5,135,458 (-)NCBI
Celera126,275,654 - 6,515,163 (-)NCBICelera
Cytogenetic Map12p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
1,1-dichloroethene  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2-hydroxypropanoic acid  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acetamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
antirheumatic drug  (ISO)
avobenzone  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
bortezomib  (ISO)
butanal  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (EXP)
clobetasol  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (EXP)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
furan  (EXP)
genistein  (ISO)
glyphosate  (EXP)
hydroquinone  (ISO)
isoprenaline  (ISO)
lead diacetate  (ISO)
melphalan  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
N-nitrosodimethylamine  (EXP)
nickel atom  (ISO)
nickel sulfate  (ISO)
oxaliplatin  (EXP)
paracetamol  (ISO)
PCB138  (ISO)
pirinixic acid  (ISO)
potassium bromate  (ISO)
potassium chromate  (ISO)
progesterone  (ISO)
propanal  (ISO)
quinolin-8-ol  (ISO)
rac-lactic acid  (ISO)
SB 431542  (ISO)
sunitinib  (ISO)
tetrachloromethane  (ISO)
topotecan  (EXP)
trichostatin A  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
valproic acid  (ISO)
vincristine  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:23886946   PMID:31505169  


Genomics

Candidate Gene Status
Fry is a candidate Gene for QTL Mcs30
Comparative Map Data
Fry
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2124,493,890 - 4,887,118 (-)NCBI
Rnor_6.0 Ensembl125,573,729 - 5,822,874 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0125,573,729 - 5,822,874 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0127,683,059 - 7,925,464 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4124,886,882 - 5,135,963 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1124,888,109 - 5,135,458 (-)NCBI
Celera126,275,654 - 6,515,163 (-)NCBICelera
Cytogenetic Map12p12NCBI
FRY
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1331,846,713 - 32,299,125 (+)EnsemblGRCh38hg38GRCh38
GRCh381332,031,774 - 32,299,125 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371332,605,911 - 32,873,262 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361331,503,437 - 31,768,776 (+)NCBINCBI36hg18NCBI36
Celera1313,672,265 - 13,937,607 (+)NCBI
Cytogenetic Map13q13.1NCBI
HuRef1313,416,995 - 13,682,345 (+)NCBIHuRef
CHM1_11332,572,902 - 32,838,323 (+)NCBICHM1_1
Fry
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395150,042,083 - 150,421,218 (+)NCBIGRCm39mm39
GRCm39 Ensembl5150,042,110 - 150,421,218 (+)Ensembl
GRCm385150,118,618 - 150,497,753 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5150,118,645 - 150,497,753 (+)EnsemblGRCm38mm10GRCm38
MGSCv375151,062,505 - 151,300,328 (+)NCBIGRCm37mm9NCBIm37
MGSCv365150,528,309 - 150,766,132 (+)NCBImm8
Celera5148,266,348 - 148,502,279 (+)NCBICelera
Cytogenetic Map5G3NCBI
cM Map589.36NCBI
Fry
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543113,562,116 - 13,827,594 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543113,562,116 - 13,903,335 (-)NCBIChiLan1.0ChiLan1.0
FRY
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11331,723,484 - 31,990,801 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1331,541,109 - 31,990,801 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01313,104,961 - 13,555,862 (+)NCBIMhudiblu_PPA_v0panPan3
FRY
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1257,832,080 - 8,092,310 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl257,833,263 - 8,166,494 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha257,864,036 - 8,298,757 (-)NCBI
ROS_Cfam_1.0257,932,138 - 8,192,289 (-)NCBI
UMICH_Zoey_3.1257,830,403 - 8,096,441 (-)NCBI
UNSW_CanFamBas_1.0257,828,943 - 8,263,094 (-)NCBI
UU_Cfam_GSD_1.0257,886,283 - 8,147,012 (-)NCBI
Fry
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_ltri_2NW_024404945169,026,531 - 169,425,981 (-)NCBI
SpeTri2.0NW_00493647226,526,153 - 26,925,620 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FRY
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl118,343,265 - 8,765,082 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1118,518,514 - 8,765,089 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2118,441,407 - 8,513,599 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FRY
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1310,782,318 - 11,051,489 (+)NCBI
ChlSab1.1 Ensembl310,784,215 - 11,050,308 (+)Ensembl
Fry
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247765,608,660 - 6,109,314 (-)NCBI

Position Markers
D12Mco3  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0125,637,298 - 5,637,400NCBIRnor6.0
RGSC_v3.4124,949,837 - 4,949,939RGDRGSC3.4
RGSC_v3.1124,949,837 - 4,949,939RGD
Celera126,337,997 - 6,338,097UniSTS
Cytogenetic Map12p12UniSTS
RH144537  
Rat AssemblyChrPosition (strand)SourceJBrowse
Celera126,449,327 - 6,449,557UniSTS
Cytogenetic Map12p12UniSTS
AF346502  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0125,884,960 - 5,885,167NCBIRnor6.0
Rnor_5.0127,989,765 - 7,989,972UniSTSRnor5.0
RGSC_v3.4125,196,000 - 5,196,207UniSTSRGSC3.4
Celera126,577,824 - 6,578,031UniSTS
Cytogenetic Map12p12UniSTS
BF400157  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0125,815,014 - 5,815,139NCBIRnor6.0
Rnor_5.0127,917,244 - 7,917,369UniSTSRnor5.0
RH 3.4 Map1233.53UniSTS
Cytogenetic Map12p12UniSTS
BE107763  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0125,943,531 - 5,943,716NCBIRnor6.0
Rnor_5.0128,047,462 - 8,047,647UniSTSRnor5.0
RGSC_v3.4125,250,189 - 5,250,374UniSTSRGSC3.4
Celera126,631,691 - 6,631,876UniSTS
RH 3.4 Map1233.94UniSTS
Cytogenetic Map12p12UniSTS
RH137545  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map12p12UniSTS
RH142005  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0125,602,948 - 5,603,151NCBIRnor6.0
Rnor_5.0127,712,265 - 7,712,468UniSTSRnor5.0
RGSC_v3.4124,915,709 - 4,915,912UniSTSRGSC3.4
Celera126,304,280 - 6,304,483UniSTS
Cytogenetic Map12p12UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)1249257845492578Rat
2302042Pia38Pristane induced arthritis QTL 383.50.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)12251344247513442Rat
724526Uae3Urinary albumin excretion QTL 34.90.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)12540609412355490Rat
737979Pia22Pristane induced arthritis QTL 2253.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12247568747475687Rat
1581516Cm56Cardiac mass QTL 564.20.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)12130749723Rat
1598855Bp294Blood pressure QTL 2943.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12136919844Rat
634350Apr4Acute phase response QTL 46orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)12421005149210051Rat
634351Apr5Acute phase response QTL 56.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)12251344247513442Rat
1300174Bw15Body weight QTL 152.93body mass (VT:0001259)body weight loss (CMO:0001399)12111765163Rat
2312418Kidm41Kidney mass QTL 413.70.0001kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)12122650917Rat
6893681Bw109Body weight QTL 1092.30.004body mass (VT:0001259)body weight (CMO:0000012)12123758197Rat
7411660Foco28Food consumption QTL 2810.90.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)1215081045150810Rat
7243862Mcs30Mammary carcinoma susceptibility QTL 308.62mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)12125813910257059Rat
9590086Insglur6Insulin/glucose ratio QTL 618.970.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)1215081045150810Rat
8694179Bw150Body weight QTL 1502.90.001body mass (VT:0001259)body weight gain (CMO:0000420)1215081045150810Rat
7411586Foco5Food consumption QTL 55.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)1215081045150810Rat
7411595Foco9Food consumption QTL 940.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)1215081045150810Rat
7411545Bw128Body weight QTL 1285.20.001body mass (VT:0001259)body weight gain (CMO:0000420)1215081045150810Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1215081045150810Rat
7387292Kidm42Kidney mass QTL 423.030.0004kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)12138334225Rat
10450854Stl34Serum triglyceride level QTL 343.50.05blood LDL triglyceride amount (VT:0010699)blood lipoprotein triglyceride level (CMO:0002685)12122853017Rat
10755457Coatc14Coat color QTL 140.01759coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)12123035872Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:539
Count of miRNA genes:247
Interacting mature miRNAs:318
Transcripts:ENSRNOT00000041365
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 42 2 3 8 11 62 5 8 11 8
Low 3 1 49 35 16 35 12 30 33
Below cutoff 6 6 6

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000041365   ⟹   ENSRNOP00000045830
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl125,575,432 - 5,773,036 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000075920   ⟹   ENSRNOP00000067905
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl125,693,414 - 5,822,874 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000076483   ⟹   ENSRNOP00000068451
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl125,573,729 - 5,682,608 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000077167   ⟹   ENSRNOP00000074063
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl125,573,730 - 5,685,448 (-)Ensembl
RefSeq Acc Id: NM_001170398   ⟹   NP_001163869
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2124,493,890 - 4,736,936 (-)NCBI
Rnor_6.0125,573,729 - 5,822,874 (-)NCBI
Rnor_5.0127,683,059 - 7,925,464 (-)NCBI
RGSC_v3.4124,886,882 - 5,135,963 (-)RGD
Celera126,275,654 - 6,515,163 (-)RGD
Sequence:
RefSeq Acc Id: XM_039089329   ⟹   XP_038945257
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2124,493,890 - 4,738,410 (-)NCBI
RefSeq Acc Id: XM_039089330   ⟹   XP_038945258
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2124,493,890 - 4,700,261 (-)NCBI
RefSeq Acc Id: XM_039089331   ⟹   XP_038945259
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2124,493,890 - 4,738,411 (-)NCBI
RefSeq Acc Id: XM_039089332   ⟹   XP_038945260
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2124,493,890 - 4,700,261 (-)NCBI
RefSeq Acc Id: XM_039089333   ⟹   XP_038945261
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2124,493,890 - 4,738,410 (-)NCBI
RefSeq Acc Id: XM_039089334   ⟹   XP_038945262
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2124,493,890 - 4,887,118 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_001163869   ⟸   NM_001170398
- Sequence:
RefSeq Acc Id: ENSRNOP00000074063   ⟸   ENSRNOT00000077167
RefSeq Acc Id: ENSRNOP00000067905   ⟸   ENSRNOT00000075920
RefSeq Acc Id: ENSRNOP00000045830   ⟸   ENSRNOT00000041365
RefSeq Acc Id: ENSRNOP00000068451   ⟸   ENSRNOT00000076483
RefSeq Acc Id: XP_038945262   ⟸   XM_039089334
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038945259   ⟸   XM_039089331
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038945261   ⟸   XM_039089333
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038945257   ⟸   XM_039089329
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038945260   ⟸   XM_039089332
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038945258   ⟸   XM_039089330
- Peptide Label: isoform X2
Protein Domains
MOR2-PAG1_C   MOR2-PAG1_mid   MOR2-PAG1_N

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307034 AgrOrtholog
Ensembl Genes ENSRNOG00000000894 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000045830 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000067905 UniProtKB/TrEMBL
  ENSRNOP00000068451 UniProtKB/TrEMBL
  ENSRNOP00000074063 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000041365 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000075920 UniProtKB/TrEMBL
  ENSRNOT00000076483 UniProtKB/TrEMBL
  ENSRNOT00000077167 UniProtKB/TrEMBL
InterPro ARM-type_fold UniProtKB/TrEMBL
  Cell_morpho_N UniProtKB/TrEMBL
  Cell_Morphogen_C UniProtKB/TrEMBL
  Furry/Tao3/Mor2 UniProtKB/TrEMBL
  MOR2-PAG1_mid UniProtKB/TrEMBL
KEGG Report rno:304244 UniProtKB/TrEMBL
NCBI Gene 304244 ENTREZGENE
PANTHER PTHR12295 UniProtKB/TrEMBL
Pfam MOR2-PAG1_C UniProtKB/TrEMBL
  MOR2-PAG1_mid UniProtKB/TrEMBL
  MOR2-PAG1_N UniProtKB/TrEMBL
PhenoGen Fry PhenoGen
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
UniProt A0A096MIW7_RAT UniProtKB/TrEMBL
  A0A096MKB4_RAT UniProtKB/TrEMBL
  A0A0G2K749_RAT UniProtKB/TrEMBL
  C0IXW5_RAT UniProtKB/TrEMBL
  C0IXW6_RAT UniProtKB/TrEMBL
  E9PTY6_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-09 Fry  FRY microtubule binding protein  Fry  furry homolog (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-06-16 Fry  furry homolog (Drosophila)  RGD1307034  similar to hypothetical protein CG003   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1307034  similar to hypothetical protein CG003   RGD1307034_predicted  similar to hypothetical protein CG003 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-20 RGD1307034_predicted  similar to hypothetical protein CG003 (predicted)  LOC304244_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC304244_predicted  similar to hypothetical protein CG003 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL