Tbx3 (T-box transcription factor 3) - Rat Genome Database

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Gene: Tbx3 (T-box transcription factor 3) Rattus norvegicus
Analyze
Symbol: Tbx3
Name: T-box transcription factor 3
RGD ID: 735203
Description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in negative regulation of apoptotic process. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. Predicted to be active in cilium. Biomarker of myocardial infarction. Human ortholog(s) of this gene implicated in ulnar-mammary syndrome. Orthologous to human TBX3 (T-box transcription factor 3); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: T-box 3; T-box 3 (ulnar mammary syndrome); T-box protein 3; T-box transcription factor TBX3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21236,879,924 - 36,894,849 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1236,881,445 - 36,893,708 (-)Ensembl
Rnor_6.01242,479,518 - 42,494,588 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1242,480,560 - 42,492,526 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01244,326,928 - 44,342,670 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41238,155,494 - 38,166,670 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11238,018,881 - 38,030,058 (-)NCBI
Celera1238,555,497 - 38,566,664 (-)NCBICelera
Cytogenetic Map12q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-epigallocatechin 3-gallate  (ISO)
1,1-dichloroethene  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP,ISO)
actinomycin D  (ISO)
afimoxifene  (ISO)
all-trans-retinoic acid  (ISO)
amiodarone  (ISO)
amitrole  (ISO)
antirheumatic drug  (ISO)
aristolochic acid  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bromobenzene  (EXP)
butanal  (ISO)
cadmium dichloride  (ISO)
cannabidiol  (EXP)
carbon nanotube  (ISO)
carmustine  (ISO)
cefaloridine  (EXP)
chlordecone  (ISO)
ciguatoxin CTX1B  (ISO)
clofibrate  (ISO)
cobalt atom  (ISO)
copper(II) sulfate  (ISO)
Cuprizon  (EXP)
cycloheximide  (ISO)
cylindrospermopsin  (ISO)
cyproconazole  (ISO)
dexamethasone  (EXP,ISO)
diclofenac  (ISO)
dicrotophos  (ISO)
dimethoate  (ISO)
disodium selenite  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
endosulfan  (EXP)
enzacamene  (ISO)
fenvalerate  (ISO)
folic acid  (ISO)
fonofos  (ISO)
fulvestrant  (ISO)
furan  (EXP)
GW 4064  (ISO)
hydrogen peroxide  (ISO)
indometacin  (ISO)
Iopanoic acid  (ISO)
leflunomide  (ISO)
metformin  (EXP)
methimazole  (ISO)
methoxychlor  (ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (ISO)
Muraglitazar  (EXP)
N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide  (ISO)
nickel atom  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
parathion  (ISO)
PD 0325901  (ISO)
PD173074  (ISO)
pentanal  (ISO)
phenformin  (EXP)
phenobarbital  (ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
propanal  (ISO)
propiconazole  (ISO)
Ptaquiloside  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
ritodrine  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sorafenib  (ISO)
sulindac  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
terbufos  (ISO)
Tesaglitazar  (EXP)
testosterone  (EXP)
tetrachloromethane  (EXP,ISO)
tetraphene  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
troglitazone  (ISO)
urethane  (ISO)
valproic acid  (ISO)
zinc atom  (ISO)
zinc sulfate  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
animal organ morphogenesis  (ISO)
anterior/posterior axis specification, embryo  (ISO,ISS)
atrioventricular bundle cell differentiation  (ISO)
atrioventricular canal development  (ISO)
atrioventricular canal morphogenesis  (ISO)
blood vessel development  (ISO)
branching involved in mammary gland duct morphogenesis  (ISO)
cardiac chamber development  (IBA)
cardiac epithelial to mesenchymal transition  (ISO)
cardiac jelly development  (ISO)
cardiac muscle cell differentiation  (ISO)
cardiac muscle cell fate commitment  (ISO)
cell fate specification  (IBA)
cellular senescence  (ISO,ISS)
central nervous system development  (IBA)
embryonic digit morphogenesis  (ISO,ISS)
embryonic forelimb morphogenesis  (ISO,ISS)
embryonic heart tube development  (ISO)
embryonic hindlimb morphogenesis  (ISO)
endocardial cushion formation  (ISO)
female genitalia development  (ISO,ISS)
follicle-stimulating hormone secretion  (ISO,ISS)
forelimb morphogenesis  (ISO)
heart looping  (IBA,ISO)
heart morphogenesis  (ISO)
hepatoblast differentiation  (IEA,ISO)
in utero embryonic development  (ISO)
inner ear morphogenesis  (ISO)
limb morphogenesis  (ISO)
limbic system development  (ISO)
luteinizing hormone secretion  (ISO,ISS)
male genitalia development  (ISO,ISS)
mammary gland development  (ISO,ISS)
mammary placode formation  (ISO)
mesoderm morphogenesis  (ISO,ISS)
negative regulation of apoptotic process  (IMP,ISO,ISS)
negative regulation of cell proliferation involved in heart morphogenesis  (ISO)
negative regulation of epithelial cell differentiation  (ISO)
negative regulation of myoblast differentiation  (ISO,ISS)
negative regulation of stem cell differentiation  (IEA,ISO)
negative regulation of transcription by RNA polymerase II  (IEA,IMP,ISO)
negative regulation of transcription, DNA-templated  (ISO,ISS)
obsolete cell aging  (ISO)
outflow tract morphogenesis  (ISO)
positive regulation of cell cycle  (ISO,ISS)
positive regulation of cell population proliferation  (IBA,ISO)
positive regulation of stem cell proliferation  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
positive regulation of transcription, DNA-templated  (IEA,ISO)
regulation of cell population proliferation  (ISO)
regulation of protein complex stability  (ISO)
regulation of protein stability  (ISO)
regulation of transcription by RNA polymerase II  (IBA)
roof of mouth development  (ISO)
semicircular canal morphogenesis  (ISO)
sinoatrial node cell development  (ISO)
skeletal system development  (ISO,ISS)
smooth muscle cell differentiation  (ISO)
specification of animal organ position  (ISO)
stem cell population maintenance  (ISO)
stem cell proliferation  (IEA,ISO)
transcription, DNA-templated  (IEA,ISO)
ureteric peristalsis  (ISO)
ventricular septum morphogenesis  (ISO)

Cellular Component

References

References - curated
1. Ballim RD, etal., Mol Biol Cell. 2012 Jun;23(12):2362-72. doi: 10.1091/mbc.E11-09-0790. Epub 2012 Apr 25.
2. Bamshad M, etal., Am J Hum Genet. 1999 Jun;64(6):1550-62.
3. Bamshad M, etal., Nat Genet 1997 Jul;16(3):311-5.
4. Boogerd KJ, etal., Cardiovasc Res. 2008 Jun 1;78(3):485-93. doi: 10.1093/cvr/cvn049. Epub 2008 Feb 19.
5. Brinckmann M, etal., J Mol Cell Cardiol. 2009 Jul;47(1):66-75. Epub 2009 Mar 31.
6. Feng X, etal., Oncol Res. 2018 Jul 5;26(6):959-966. doi: 10.3727/096504017X15145624664031. Epub 2018 Jan 2.
7. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
8. GOA data from the GO Consortium
9. Ito A, etal., Cancer Lett. 2005 Feb 28;219(1):105-12.
10. Lachenmayer A, etal., Clin Cancer Res. 2012 Sep 15;18(18):4997-5007. doi: 10.1158/1078-0432.CCR-11-2322. Epub 2012 Jul 18.
11. Li Z, etal., Med Sci Monit. 2018 Dec 22;24:9324-9333. doi: 10.12659/MSM.909378.
12. Liang B, etal., J Hepatol. 2021 Jul;75(1):120-131. doi: 10.1016/j.jhep.2021.01.044. Epub 2021 Feb 10.
13. Lingbeek ME, etal., J Biol Chem 2002 Jul 19;277(29):26120-7. Epub 2002 May 08.
14. Miao ZF, etal., Virchows Arch. 2016 Nov;469(5):505-513. doi: 10.1007/s00428-016-2007-9. Epub 2016 Aug 24.
15. OMIM Disease Annotation Pipeline
16. RGD automated data pipeline
17. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
18. RGD automated import pipeline for gene-chemical interactions
19. RGD comprehensive gene curation
20. Shan ZZ, etal., Am J Cancer Res. 2014 Dec 15;5(1):344-53. eCollection 2015.
21. Souchelnytskyi S, etal., Proteomics. 2006 Sep;6 Suppl 2:65-8.
22. Wen B, etal., Nan Fang Yi Ke Da Xue Xue Bao. 2016 Feb;36(2):210-4.
Additional References at PubMed
PMID:10468588   PMID:11689487   PMID:11748239   PMID:12032820   PMID:12116211   PMID:12668638   PMID:16222716   PMID:17071745   PMID:17234970   PMID:17460765   PMID:17473172   PMID:18356246  
PMID:18467625   PMID:18534921   PMID:18723448   PMID:19096026   PMID:19765559   PMID:19769959   PMID:22002537   PMID:22164283   PMID:23844108   PMID:30478225  


Genomics

Comparative Map Data
Tbx3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21236,879,924 - 36,894,849 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1236,881,445 - 36,893,708 (-)Ensembl
Rnor_6.01242,479,518 - 42,494,588 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1242,480,560 - 42,492,526 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01244,326,928 - 44,342,670 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41238,155,494 - 38,166,670 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11238,018,881 - 38,030,058 (-)NCBI
Celera1238,555,497 - 38,566,664 (-)NCBICelera
Cytogenetic Map12q16NCBI
TBX3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812114,670,255 - 114,684,175 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl12114,670,255 - 114,684,175 (-)EnsemblGRCh38hg38GRCh38
GRCh3712115,108,060 - 115,121,980 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612113,592,442 - 113,606,352 (-)NCBINCBI36hg18NCBI36
Build 3412113,570,778 - 113,584,689NCBI
Celera12114,735,560 - 114,749,458 (-)NCBI
Cytogenetic Map12q24.21NCBI
HuRef12112,116,904 - 112,130,825 (-)NCBIHuRef
CHM1_112115,075,996 - 115,089,899 (-)NCBICHM1_1
T2T-CHM13v2.012114,647,343 - 114,661,251 (-)NCBI
Tbx3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395119,808,600 - 119,822,789 (+)NCBIGRCm39mm39
GRCm39 Ensembl5119,808,734 - 119,822,789 (+)Ensembl
GRCm385119,670,534 - 119,684,724 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5119,670,669 - 119,684,724 (+)EnsemblGRCm38mm10GRCm38
MGSCv375120,120,678 - 120,134,610 (+)NCBIGRCm37mm9NCBIm37
MGSCv365119,931,286 - 119,945,218 (+)NCBImm8
Celera5116,764,719 - 116,778,686 (+)NCBICelera
Cytogenetic Map5FNCBI
cM Map560.34NCBI
Tbx3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545515,988,663 - 16,000,063 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545515,988,153 - 16,000,156 (+)NCBIChiLan1.0ChiLan1.0
TBX3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.112115,618,420 - 115,632,327 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12115,620,002 - 115,631,316 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v012112,240,050 - 112,254,299 (-)NCBIMhudiblu_PPA_v0panPan3
TBX3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12611,694,885 - 11,709,594 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2611,696,565 - 11,708,918 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2611,753,296 - 11,767,965 (-)NCBI
ROS_Cfam_1.02611,953,157 - 11,967,841 (-)NCBI
ROS_Cfam_1.0 Ensembl2611,954,731 - 11,966,470 (-)Ensembl
UMICH_Zoey_3.12611,914,521 - 11,929,199 (-)NCBI
UNSW_CanFamBas_1.02611,977,110 - 11,991,787 (-)NCBI
UU_Cfam_GSD_1.02612,026,728 - 12,041,404 (-)NCBI
Tbx3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118152,235,738 - 152,248,370 (-)NCBI
SpeTri2.0NW_0049365587,230,361 - 7,243,651 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TBX3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1437,582,822 - 37,596,767 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11437,582,704 - 37,596,767 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21440,012,569 - 40,026,314 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TBX3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111109,952,100 - 109,966,328 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl11109,952,054 - 109,965,065 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037135,142,552 - 135,156,757 (+)NCBIVero_WHO_p1.0
Tbx3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474718,128,028 - 18,142,451 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462474718,128,003 - 18,142,366 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
AU047822  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21236,882,747 - 36,883,028 (+)MAPPERmRatBN7.2
Rnor_6.01242,482,341 - 42,482,621NCBIRnor6.0
Rnor_5.01244,329,751 - 44,330,031UniSTSRnor5.0
RGSC_v3.41238,156,683 - 38,156,963UniSTSRGSC3.4
Celera1238,556,680 - 38,556,962UniSTS
Cytogenetic Map12q16UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411660Foco28Food consumption QTL 2810.90.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
9590086Insglur6Insulin/glucose ratio QTL 618.970.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)12142110980Rat
8694179Bw150Body weight QTL 1502.90.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
7411586Foco5Food consumption QTL 55.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411595Foco9Food consumption QTL 940.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411545Bw128Body weight QTL 1285.20.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)12142110980Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12142450532Rat
737979Pia22Pristane induced arthritis QTL 2253.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12144465750Rat
634351Apr5Acute phase response QTL 56.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)12144503507Rat
2302042Pia38Pristane induced arthritis QTL 383.50.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)12144503507Rat
634350Apr4Acute phase response QTL 46orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)12117200546172005Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)6556449546669029Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449846669029Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)12610757946669029Rat
1302792Scl21Serum cholesterol level QTL 213.80.0011blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)12719673046669029Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)12960327746669029Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121047413746669029Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121047413746669029Rat
1331761Bp218Blood pressure QTL 2182.973arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121107382545055165Rat
61404Bw120Body weight QTL 1205.1body mass (VT:0001259)body mass index (BMI) (CMO:0000105)121235161946669029Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121281238546669029Rat
2303569Gluco44Glucose level QTL 442blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121281238546669029Rat
1549902Bp269Blood pressure QTL 269arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)121318273646669029Rat
1549912Bp268Blood pressure QTL 268arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)101318273646669029Rat
2302060Pia37Pristane induced arthritis QTL 376.10.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)121319815746669029Rat
631543Bp83Blood pressure QTL 835.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)121555082638478808Rat
631560Apr1Acute phase response QTL 16.1orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)121914436246669029Rat
737822Alc10Alcohol consumption QTL 102.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)121961087040218516Rat
5684888Pia42Pristane induced arthritis QTL 42joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)121961087042828880Rat
61324Eae5Experimental allergic encephalomyelitis QTL 514nervous system integrity trait (VT:0010566)percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time (CMO:0001402)121961087046669029Rat
70213Niddm27Non-insulin dependent diabetes mellitus QTL 273.72blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121983578938193007Rat
7411643Foco20Food consumption QTL 200.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)122032881946669029Rat
1556747Calcic1Intracellular calcium level QTL 13.6platelet calcium amount (VT:0010500)platelet intracellular calcium level (CMO:0000922)122806443340130419Rat
1300175Cm5Cardiac mass QTL 53.78heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)122806443345899022Rat
1600386Calcic2Intracellular calcium level QTL 20.001platelet physiology trait (VT:0005464)platelet intracellular calcium level (CMO:0000922)122806443346669029Rat
1331787Rf41Renal function QTL 412.998kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)122806455740218380Rat
631829Alc6Alcohol consumption QTL 64.7consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)122860752637691617Rat
1300162Bp188Blood pressure QTL 1883.19arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)123210317445899022Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:101
Count of miRNA genes:84
Interacting mature miRNAs:88
Transcripts:ENSRNOT00000011552
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 4 15 7 7 21 32 11
Low 1 39 41 34 18 34 8 10 70 14 9 8
Below cutoff 1 1 1 4

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000011552   ⟹   ENSRNOP00000011552
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1236,881,445 - 36,893,708 (-)Ensembl
Rnor_6.0 Ensembl1242,481,152 - 42,492,328 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000084018   ⟹   ENSRNOP00000074567
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1236,881,445 - 36,893,708 (-)Ensembl
Rnor_6.0 Ensembl1242,480,560 - 42,492,526 (-)Ensembl
RefSeq Acc Id: NM_181638   ⟹   NP_853669
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21236,881,559 - 36,892,737 (-)NCBI
Rnor_6.01242,481,152 - 42,492,328 (-)NCBI
Rnor_5.01244,326,928 - 44,342,670 (-)NCBI
RGSC_v3.41238,155,494 - 38,166,670 (-)RGD
Celera1238,555,497 - 38,566,664 (-)RGD
Sequence:
RefSeq Acc Id: XM_006249416   ⟹   XP_006249478
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21236,879,924 - 36,894,849 (-)NCBI
Rnor_6.01242,479,518 - 42,494,588 (-)NCBI
Rnor_5.01244,326,928 - 44,342,670 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006249417   ⟹   XP_006249479
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21236,879,924 - 36,894,053 (-)NCBI
Rnor_6.01242,479,518 - 42,493,644 (-)NCBI
Rnor_5.01244,326,928 - 44,342,670 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006249418   ⟹   XP_006249480
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21236,879,924 - 36,894,053 (-)NCBI
Rnor_6.01242,479,518 - 42,493,600 (-)NCBI
Rnor_5.01244,326,928 - 44,342,670 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039089539   ⟹   XP_038945467
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21236,879,924 - 36,894,849 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_853669   ⟸   NM_181638
- UniProtKB: Q7TST9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006249478   ⟸   XM_006249416
- Peptide Label: isoform X1
- UniProtKB: Q7TST9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006249479   ⟸   XM_006249417
- Peptide Label: isoform X1
- UniProtKB: Q7TST9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006249480   ⟸   XM_006249418
- Peptide Label: isoform X2
- UniProtKB: A0A0G2K8D7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000011552   ⟸   ENSRNOT00000011552
RefSeq Acc Id: ENSRNOP00000074567   ⟸   ENSRNOT00000084018
RefSeq Acc Id: XP_038945467   ⟸   XM_039089539
- Peptide Label: isoform X1
Protein Domains
TBX

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q7TST9-F1-model_v2 AlphaFold Q7TST9 1-743 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:735203 AgrOrtholog
BioCyc Gene G2FUF-19147 BioCyc
Ensembl Genes ENSRNOG00000008706 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000011552 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000074567 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000011552 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000084018 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.820 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro p53-like_TF_DNA-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  T-box_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TBX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TF_Brachyury UniProtKB/TrEMBL
  TF_T-box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TF_T-box_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:353305 UniProtKB/Swiss-Prot
NCBI Gene 353305 ENTREZGENE
PANTHER PTHR11267 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam T-box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TBX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tbx3 PhenoGen
PRINTS BRACHYURY UniProtKB/TrEMBL
  TBOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE TBOX_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TBOX_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TBOX_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART TBOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF49417 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K8D7 ENTREZGENE, UniProtKB/TrEMBL
  Q7TST9 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-08-05 Tbx3  T-box transcription factor 3  Tbx3  T-box 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-08 Tbx3  T-box 3    T-box 3 (ulnar mammary syndrome)  Name updated 1299863 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_disease mutation of the human homolog causes ulnar-mammary syndrome, which is characterized by defects in limb, apocrine gland, tooth and genital development 1302838