Rpl6 (ribosomal protein L6) - Rat Genome Database
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Gene: Rpl6 (ribosomal protein L6) Rattus norvegicus
Analyze
Symbol: Rpl6
Name: ribosomal protein L6
RGD ID: 619826
Description: Exhibits 5.8S rRNA binding activity; mRNA binding activity; and tRNA binding activity. Predicted to be involved in cytoplasmic translation and ribosomal large subunit assembly. Localizes to A band and cytosolic large ribosomal subunit. Orthologous to human RPL6 (ribosomal protein L6); PARTICIPATES IN ribosome biogenesis pathway; translation pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 2,4,6-trinitrotoluene; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 60S ribosomal protein L6; MGC93267; neoplasm-related protein C140
Orthologs:
Homo sapiens (human) : RPL6 (ribosomal protein L6)  HGNC  Alliance
Mus musculus (house mouse) : Rpl6 (ribosomal protein L6)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rpl6 (ribosomal protein L6)
Pan paniscus (bonobo/pygmy chimpanzee) : RPL6 (ribosomal protein L6)
Canis lupus familiaris (dog) : RPL6 (ribosomal protein L6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rpl6 (ribosomal protein L6)
Sus scrofa (pig) : RPL6 (ribosomal protein L6)
Chlorocebus sabaeus (African green monkey) : RPL6 (ribosomal protein L6)
Heterocephalus glaber (naked mole-rat) : Rpl6 (ribosomal protein L6)
more info ...
Related Pseudogenes: Rpl6-ps1  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01240,877,578 - 40,882,032 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1240,877,613 - 40,881,124 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01242,744,693 - 42,749,153 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41236,483,874 - 36,487,420 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11236,347,261 - 36,351,676 (-)NCBI
Celera1237,011,947 - 37,015,493 (-)NCBICelera
Cytogenetic Map12q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4,6-trinitrotoluene  (EXP)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-nitrofluorene  (EXP)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (EXP)
4-tert-Octylphenol  (EXP)
5-fluorouracil  (ISO)
7,12-dimethyltetraphene  (EXP)
afimoxifene  (ISO)
aflatoxin B1  (EXP,ISO)
ammonium chloride  (EXP)
arsenous acid  (ISO)
artesunate  (ISO)
atrazine  (ISO)
bisphenol A  (EXP,ISO)
bleomycin A2  (EXP)
bromobenzene  (EXP)
chromium(6+)  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
cocaine  (EXP)
cylindrospermopsin  (ISO)
diarsenic trioxide  (ISO)
dicrotophos  (ISO)
diethylstilbestrol  (EXP)
disodium selenite  (ISO)
doxorubicin  (ISO)
enzyme inhibitor  (ISO)
ethanol  (ISO)
etoposide  (ISO)
flavonoids  (EXP,ISO)
flutamide  (EXP)
fulvestrant  (ISO)
gentamycin  (EXP)
hydrogen peroxide  (ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
methapyrilene  (EXP)
methylparaben  (ISO)
miconazole  (ISO)
N-nitrosodimethylamine  (EXP)
nitroglycerin  (EXP)
ochratoxin A  (EXP)
p-tert-Amylphenol  (EXP)
paracetamol  (ISO)
perfluorooctanoic acid  (ISO)
PhIP  (EXP)
piperonyl butoxide  (EXP)
pirinixic acid  (EXP)
progesterone  (ISO)
Propiverine  (EXP)
raloxifene  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (ISO)
sodium arsenite  (EXP,ISO)
sunitinib  (ISO)
testosterone  (ISO)
ursodeoxycholic acid  (ISO)
valproic acid  (ISO)
vincristine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:398910   PMID:8185817   PMID:12962325   PMID:15121898   PMID:15169875   PMID:15489334   PMID:16635246   PMID:19946888   PMID:21423176   PMID:21630459   PMID:22082260   PMID:22658674  
PMID:22871113   PMID:24930395   PMID:25468996   PMID:25957688   PMID:26316108   PMID:29476059  


Genomics

Comparative Map Data
Rpl6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01240,877,578 - 40,882,032 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1240,877,613 - 40,881,124 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01242,744,693 - 42,749,153 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41236,483,874 - 36,487,420 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11236,347,261 - 36,351,676 (-)NCBI
Celera1237,011,947 - 37,015,493 (-)NCBICelera
Cytogenetic Map12q16NCBI
RPL6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl12112,405,190 - 112,418,838 (-)EnsemblGRCh38hg38GRCh38
GRCh3812112,405,181 - 112,418,850 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3712112,842,994 - 112,856,647 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612111,327,377 - 111,331,826 (-)NCBINCBI36hg18NCBI36
Build 3412111,305,714 - 111,310,141NCBI
Celera12112,470,140 - 112,474,589 (-)NCBI
Cytogenetic Map12q24.13NCBI
HuRef12109,855,563 - 109,860,012 (-)NCBIHuRef
CHM1_112112,811,636 - 112,825,335 (-)NCBICHM1_1
Rpl6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395121,342,564 - 121,347,304 (+)NCBI
GRCm385121,204,501 - 121,209,241 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5121,204,481 - 121,209,241 (+)EnsemblGRCm38mm10GRCm38
MGSCv375121,654,510 - 121,659,250 (+)NCBIGRCm37mm9NCBIm37
MGSCv365121,465,118 - 121,469,584 (+)NCBImm8
Celera5118,294,425 - 118,299,167 (+)NCBICelera
Cytogenetic Map5FNCBI
Rpl6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554828,917,777 - 8,923,150 (-)NCBIChiLan1.0ChiLan1.0
RPL6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.112113,398,795 - 113,403,247 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v012110,002,667 - 110,008,899 (-)NCBIMhudiblu_PPA_v0panPan3
RPL6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1269,970,416 - 9,975,897 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Rpl6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049366682,584,829 - 2,588,236 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RPL6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1439,303,337 - 39,312,319 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11439,302,447 - 39,309,239 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21441,805,405 - 41,812,197 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RPL6
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111107,648,325 - 107,650,073 (-)NCBI
Rpl6
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474719,821,875 - 19,826,605 (+)NCBI

Position Markers
RH133958  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01240,877,737 - 40,878,149NCBIRnor6.0
Rnor_6.06128,738,980 - 128,739,166NCBIRnor6.0
Rnor_5.06137,936,060 - 137,936,246UniSTSRnor5.0
Rnor_5.01242,744,852 - 42,745,264UniSTSRnor5.0
RGSC_v3.46129,221,394 - 129,221,580UniSTSRGSC3.4
RGSC_v3.41236,484,031 - 36,484,443UniSTSRGSC3.4
Celera6121,447,251 - 121,447,437UniSTS
Celera1237,012,104 - 37,012,516UniSTS
Cytogenetic Map6q32UniSTS
Cytogenetic Map12q16UniSTS
RH 3.4 Map12615.8UniSTS
RH 3.4 Map12613.0UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590086Insglur6Insulin/glucose ratio QTL 618.970.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)1215081045150810Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1215081045150810Rat
7411545Bw128Body weight QTL 1285.20.001body mass (VT:0001259)body weight gain (CMO:0000420)1215081045150810Rat
7411586Foco5Food consumption QTL 55.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)1215081045150810Rat
7411660Foco28Food consumption QTL 2810.90.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)1215081045150810Rat
7411595Foco9Food consumption QTL 940.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)1215081045150810Rat
8694179Bw150Body weight QTL 1502.90.001body mass (VT:0001259)body weight gain (CMO:0000420)1215081045150810Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)1249257845492578Rat
737979Pia22Pristane induced arthritis QTL 2253.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12247568747475687Rat
634351Apr5Acute phase response QTL 56.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)12251344247513442Rat
2302042Pia38Pristane induced arthritis QTL 383.50.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)12251344247513442Rat
634350Apr4Acute phase response QTL 46orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)12421005149210051Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)6922362652716770Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12922362652716770Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12922362652716770Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12922362652716770Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12922362652716770Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12922362652716770Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12922363052716770Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)12978983452716770Rat
1331761Bp218Blood pressure QTL 2182.973arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121312721150320041Rat
61404Bw120Body weight QTL 1205.1body mass (VT:0001259)body mass index (BMI) (CMO:0000105)121441977552716770Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)121502198652716770Rat
61421Cia12Collagen induced arthritis QTL 124.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)121571460941291738Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121590890052716770Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121590890052716770Rat
631543Bp83Blood pressure QTL 835.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)121718558044098244Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121834247752716770Rat
2303569Gluco44Glucose level QTL 442blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121834247752716770Rat
2302060Pia37Pristane induced arthritis QTL 376.10.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)121872904352716770Rat
1549902Bp269Blood pressure QTL 269arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)121875259352716770Rat
1549912Bp268Blood pressure QTL 268arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)101875259352716770Rat
737822Alc10Alcohol consumption QTL 102.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)122265070245946937Rat
5684888Pia42Pristane induced arthritis QTL 42joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)122265070248598906Rat
61324Eae5Experimental allergic encephalomyelitis QTL 514nervous system integrity trait (VT:0010566)percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time (CMO:0001402)122265070252716770Rat
1298081Cia25Collagen induced arthritis QTL 254.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)122265072141291738Rat
70213Niddm27Non-insulin dependent diabetes mellitus QTL 273.72blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)122287629743799153Rat
631560Apr1Acute phase response QTL 16.1orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)122490659052716770Rat
7411643Foco20Food consumption QTL 200.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)122609884552716770Rat
70169Eae13Experimental allergic encephalomyelitis QTL 130.032nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)122719024042196641Rat
8693658Alc33Alcohol consumption QTL 332.10.68drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)122911360949560679Rat
8693635Alc28Alcohol consumption QTL 282.70.439drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)122911360950757185Rat
1556747Calcic1Intracellular calcium level QTL 13.6platelet calcium amount (VT:0010500)platelet intracellular calcium level (CMO:0000922)123172356547433663Rat
1300175Cm5Cardiac mass QTL 53.78heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)123172356551955754Rat
1600386Calcic2Intracellular calcium level QTL 20.001platelet physiology trait (VT:0005464)platelet intracellular calcium level (CMO:0000922)123172356552716770Rat
1331787Rf41Renal function QTL 412.998kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)123172368845946802Rat
631829Alc6Alcohol consumption QTL 64.7consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)123228978243305579Rat
1300162Bp188Blood pressure QTL 1883.19arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)123752188451955754Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:230
Count of miRNA genes:156
Interacting mature miRNAs:170
Transcripts:ENSRNOT00000034951, ENSRNOT00000050204
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 1 9 6 2 6 6 10 15
Medium 2 43 51 35 17 35 8 11 68 25 26 11 8
Low
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_053971 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006249378 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AABR07036375 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01072549 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC061784 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC078761 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC097295 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473973 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212231 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213078 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216758 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217408 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217744 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218446 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220180 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220346 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220471 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220503 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220678 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220699 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220887 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221615 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222331 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222465 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223301 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226632 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227955 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227974 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228583 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228665 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229345 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229355 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229484 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229571 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229675 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229820 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229854 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229857 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229943 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230222 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232778 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233105 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233198 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233475 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234880 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234931 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ235095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X87107 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000034951   ⟹   ENSRNOP00000038065
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1240,877,613 - 40,881,124 (-)Ensembl
RefSeq Acc Id: NM_053971   ⟹   NP_446423
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01240,877,580 - 40,881,126 (-)NCBI
Rnor_5.01242,744,693 - 42,749,153 (-)NCBI
RGSC_v3.41236,483,874 - 36,487,420 (-)RGD
Celera1237,011,947 - 37,015,493 (-)RGD
Sequence:
RefSeq Acc Id: XM_006249378   ⟹   XP_006249440
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01240,877,578 - 40,882,032 (-)NCBI
Rnor_5.01242,744,693 - 42,749,153 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_446423   ⟸   NM_053971
- UniProtKB: P21533 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006249440   ⟸   XM_006249378
- Peptide Label: isoform X1
- UniProtKB: P21533 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000038065   ⟸   ENSRNOT00000034951
Protein Domains
Ribosomal_L6e_N

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698659
Promoter ID:EPDNEW_R9184
Type:multiple initiation site
Name:Rpl6_1
Description:ribosomal protein L6
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01240,881,058 - 40,881,118EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619826 AgrOrtholog
Ensembl Genes ENSRNOG00000025936 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000038065 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000034951 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 2.30.30.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:5623836 IMAGE-MGC_LOAD
  IMAGE:7123086 IMAGE-MGC_LOAD
  IMAGE:7446680 IMAGE-MGC_LOAD
InterPro 60S_ribosomal_L6E UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KOW_RPL6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rib_L2_dom2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ribosomal_L6_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Translation_prot_SH3-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:117042 UniProtKB/Swiss-Prot
MGC_CLONE MGC:114280 IMAGE-MGC_LOAD
  MGC:72343 IMAGE-MGC_LOAD
  MGC:93267 IMAGE-MGC_LOAD
NCBI Gene 117042 ENTREZGENE
PANTHER PTHR10715 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ribosomal_L6e UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ribosomal_L6e_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rpl6 PhenoGen
PROSITE RIBOSOMAL_L6E UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50104 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniGene Rn.217183 ENTREZGENE
  Rn.234072 ENTREZGENE
  Rn.2660 ENTREZGENE
UniProt P21533 ENTREZGENE
  Q6P790_RAT UniProtKB/TrEMBL
  RL6_RAT UniProtKB/Swiss-Prot
UniProt Secondary Q4QRA9 UniProtKB/Swiss-Prot
  Q64624 UniProtKB/Swiss-Prot
  Q68G26 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Rpl6  ribosomal protein L6      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Rpl6  ribosomal protein L6      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_protein 296 amino acids 633920
gene_transcript 7 to 10 copies of the gene 633920