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Gene: Oas1a (2'-5' oligoadenylate synthetase 1A) Rattus norvegicus
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Symbol: Oas1a
Name: 2'-5' oligoadenylate synthetase 1A
Description: Exhibits 2'-5'-oligoadenylate synthetase activity. Predicted to be involved in several processes, including cellular response to interferon-alpha; glucose homeostasis; and negative regulation of viral genome replication. Localizes to the nucleus. Orthologous to human OAS1 (2'-5'-oligoadenylate synthetase 1); PARTICIPATES IN hepatitis C pathway; influenza A pathway; measles pathway; INTERACTS WITH 3,3',4,4',5-pentachlorobiphenyl; Actein; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: (2-5')oligo(A) synthase 1; (2-5')oligo(A) synthase 1A; (2-5')oligo(A) synthetase 1; 2',5'-oligoadenylate synthetase 1, 40/46kDa; 2'-5' oligoadenylate synthetase 1G; 2'-5'-oligoadenylate synthase 1; 2'-5'-oligoadenylate synthase 1A; 2'-5'-oligoadenylate synthetase 1; 2-5A synthase 1; 2-5A synthase 1A; 2-5A synthetase 1; 25 oligoadenylate synthetase; MGC93097; Oas1; Oas1g
Orthologs:
Homo sapiens (human) : OAS1 (2'-5'-oligoadenylate synthetase 1)  HGNC  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : OAS1 (2'-5'-oligoadenylate synthetase 1)
Canis lupus familiaris (dog) : OAS1 (2'-5'-oligoadenylate synthetase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Oas1 (2'-5'-oligoadenylate synthetase 1)
Sus scrofa (pig) : OAS1 (2'-5'-oligoadenylate synthetase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01241,200,680 - 41,211,393 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01243,064,691 - 43,075,400 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41236,806,061 - 36,816,722 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11236,669,448 - 36,680,110 (+)NCBI
Celera1237,333,307 - 37,343,967 (+)NCBICelera
Cytogenetic Map12q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Oas1a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621760
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.