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Gene: Tmem233 (transmembrane protein 233) Rattus norvegicus

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Symbol:

Tmem233

Name:

transmembrane protein 233

RGD ID:

1597489

Description:

Predicted to be located in plasma membrane. Predicted to be active in membrane. Orthologous to human TMEM233 (transmembrane protein 233); INTERACTS WITH acrylamide; alpha-Zearalanol; furan.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC687797; similar to tumor suppressor candidate 5

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TMEM233 (transmembrane protein 233)	HGNC	Ensembl
Mus musculus (house mouse):	Tmem233 (transmembrane protein 233)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Tmem233 (transmembrane protein 233)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TMEM233 (transmembrane protein 233)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TMEM233 (transmembrane protein 233)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Tmem233 (transmembrane protein 233)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TMEM233 (transmembrane protein 233)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TMEM233 (transmembrane protein 233)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tmem233 (transmembrane protein 233)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Tmem233 (transmembrane protein 233)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	TMEM233 (transmembrane protein 233)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	46,189,247 - 46,230,434 (+)	NCBI		GRCr8
mRatBN7.2	12	40,528,515 - 40,569,611 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	40,528,499 - 40,578,608 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	12	41,701,253 - 41,742,485 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	42,314,963 - 42,356,209 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	41,375,437 - 41,416,673 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	46,287,405 - 46,297,570 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	46,257,343 - 46,287,546 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	12	48,098,446 - 48,099,228 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	12	41,775,433 - 41,775,876 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	12	42,156,713 - 42,207,682 (+)	NCBI		Celera
Cytogenetic Map	12	q16	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tmem233	Rat	2,2',5,5'-tetrachlorobiphenyl	increases expression	ISO	TMEM233 (Homo sapiens)	6480464	2 more ...	CTD	PMID:36804509
Tmem233	Rat	4,4'-sulfonyldiphenol	decreases methylation	ISO	Tmem233 (Mus musculus)	6480464	bisphenol S results in decreased methylation of TMEM233 exon	CTD	PMID:33297965
Tmem233	Rat	acrylamide	decreases expression	EXP		6480464	Acrylamide results in decreased expression of TMEM233 mRNA	CTD	PMID:28959563
Tmem233	Rat	alpha-Zearalanol	decreases expression	EXP		6480464	Zeranol results in decreased expression of TMEM233 mRNA	CTD	PMID:35163327
Tmem233	Rat	alpha-Zearalanol	multiple interactions	EXP		6480464	[Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of TMEM233 mRNA	CTD	PMID:35163327
Tmem233	Rat	benzo[a]pyrene	increases methylation	ISO	TMEM233 (Homo sapiens)	6480464	Benzo(a)pyrene results in increased methylation of TMEM233 exon	CTD	PMID:27901495
Tmem233	Rat	benzo[a]pyrene	affects methylation	ISO	TMEM233 (Homo sapiens)	6480464	Benzo(a)pyrene affects the methylation of TMEM233 intron	CTD	PMID:30157460
Tmem233	Rat	benzo[a]pyrene	decreases methylation	ISO	TMEM233 (Homo sapiens)	6480464	Benzo(a)pyrene results in decreased methylation of TMEM233 3' UTR and Benzo(a)pyrene results in decreased methylation of TMEM233 promoter	CTD	PMID:27901495
Tmem233	Rat	benzo[e]pyrene	increases methylation	ISO	TMEM233 (Homo sapiens)	6480464	benzo(e)pyrene results in increased methylation of TMEM233 intron	CTD	PMID:30157460
Tmem233	Rat	bisphenol A	decreases methylation	ISO	Tmem233 (Mus musculus)	6480464	bisphenol A results in decreased methylation of TMEM233 promoter	CTD	PMID:27312807
Tmem233	Rat	chlorpyrifos	decreases expression	ISO	Tmem233 (Mus musculus)	6480464	Chlorpyrifos results in decreased expression of TMEM233 mRNA	CTD	PMID:32715474
Tmem233	Rat	dexamethasone	decreases expression	ISO	TMEM233 (Homo sapiens)	6480464	Dexamethasone results in decreased expression of TMEM233 mRNA	CTD	PMID:25047013
Tmem233	Rat	epoxiconazole	decreases expression	ISO	Tmem233 (Mus musculus)	6480464	epoxiconazole results in decreased expression of TMEM233 mRNA	CTD	PMID:35436446
Tmem233	Rat	furan	decreases expression	EXP		6480464	furan results in decreased expression of TMEM233 mRNA	CTD	PMID:26194646
Tmem233	Rat	methapyrilene	increases methylation	ISO	TMEM233 (Homo sapiens)	6480464	Methapyrilene results in increased methylation of TMEM233 intron	CTD	PMID:30157460
Tmem233	Rat	perfluorooctanoic acid	multiple interactions	EXP		6480464	[Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of TMEM233 mRNA	CTD	PMID:35163327
Tmem233	Rat	sodium arsenite	increases expression	ISO	TMEM233 (Homo sapiens)	6480464	sodium arsenite results in increased expression of TMEM233 mRNA	CTD	PMID:38568856
Tmem233	Rat	temozolomide	decreases expression	ISO	TMEM233 (Homo sapiens)	6480464	Temozolomide results in decreased expression of TMEM233 mRNA	CTD	PMID:31758290

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tmem233	Rat	membrane	located_in	IEA	UniProtKB-KW:KW-0472	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Tmem233	Rat	membrane	located_in	IEA	InterPro:IPR007593	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Tmem233	Rat	membrane	is_active_in	IBA	MGI:1916267 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Tmem233	Rat	membrane	located_in	IEA	UniProtKB-SubCell:SL-0162	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Tmem233	Rat	plasma membrane	located_in	ISO	TMEM233 (Homo sapiens)	1624291	PMID:37117223	RGD	PMID:37117223
Tmem233	Rat	plasma membrane	located_in	IEA	UniProtKB:B4DJY2 and ensembl:ENSP00000403130	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tmem233	Rat	protein binding	enables	ISO	TMEM233 (Homo sapiens)	1624291	UniProtKB:Q15858 and PMID:37117223	RGD	PMID:37117223
Tmem233	Rat	protein binding	enables	ISO	Tmem233 (Mus musculus)	1624291	UniProtKB:Q62205 and PMID:37117223	RGD	PMID:37117223

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

PMID:8889548

Tmem233
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	46,189,247 - 46,230,434 (+)	NCBI		GRCr8
mRatBN7.2	12	40,528,515 - 40,569,611 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	40,528,499 - 40,578,608 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	12	41,701,253 - 41,742,485 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	42,314,963 - 42,356,209 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	41,375,437 - 41,416,673 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	46,287,405 - 46,297,570 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	46,257,343 - 46,287,546 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	12	48,098,446 - 48,099,228 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	12	41,775,433 - 41,775,876 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	12	42,156,713 - 42,207,682 (+)	NCBI		Celera
Cytogenetic Map	12	q16	NCBI

TMEM233
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	119,593,774 - 119,654,295 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	119,593,774 - 119,643,075 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	12	120,031,579 - 120,080,880 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	118,515,647 - 118,563,001 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	12	119,664,354 - 119,712,412 (+)	NCBI		Celera
Cytogenetic Map	12	q24.23	NCBI
HuRef	12	117,039,657 - 117,087,590 (+)	NCBI		HuRef
CHM1_1	12	119,998,984 - 120,047,050 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	12	119,581,202 - 119,641,838 (+)	NCBI		T2T-CHM13v2.0

Tmem233
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	116,176,807 - 116,221,326 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	116,176,814 - 116,221,303 (-)	Ensembl		GRCm39 Ensembl
GRCm38	5	116,038,755 - 116,083,267 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	116,038,755 - 116,083,244 (-)	Ensembl	GRCm38		mm10	GRCm38
GRCm38.p6 Ensembl	5	116,038,755 - 116,083,246 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	116,490,541 - 116,533,255 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	5	116,301,573 - 116,344,243 (-)	NCBI		MGSCv36	mm8
Celera	5	113,141,220 - 113,187,179 (-)	NCBI		Celera
Cytogenetic Map	5	F	NCBI
cM Map	5	56.1	NCBI

Tmem233
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955455	11,903,329 - 11,942,229 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955455	11,903,329 - 11,942,229 (-)	NCBI	ChiLan1.0	ChiLan1.0

TMEM233
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	127,659,435 - 127,708,983 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	127,655,822 - 127,705,362 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	117,172,620 - 117,222,197 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	120,550,547 - 120,599,347 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	120,550,547 - 120,598,598 (+)	Ensembl	panpan1.1		panPan2

TMEM233
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	26	15,653,031 - 15,688,556 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	26	15,653,020 - 15,686,539 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	26	15,658,051 - 15,693,400 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	26	15,921,527 - 15,948,568 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	26	15,921,303 - 15,947,005 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	26	15,890,849 - 15,926,207 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	26	15,958,766 - 15,994,170 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	26	15,999,987 - 16,035,325 (+)	NCBI		UU_Cfam_GSD_1.0

Tmem233
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	146,690,544 - 146,715,002 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936668	1,177,717 - 1,213,825 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TMEM233
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	33,224,397 - 33,276,683 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	33,223,574 - 33,315,609 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	35,169,961 - 35,373,884 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TMEM233
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	114,941,751 - 114,987,042 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	114,943,403 - 114,989,190 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	130,117,937 - 130,164,044 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tmem233
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624747	13,948,577 - 13,992,445 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624747	13,948,951 - 13,992,751 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Tmem233
678 total Variants

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631560	Apr1	Acute phase response QTL 1	6.1		orosomucoid 1 amount (VT:0010541)	plasma orosomucoid 1 level (CMO:0001467)	12	19144362	46669029	Rat
8552964	Pigfal17	Plasma insulin-like growth factor 1 level QTL 17	3.5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	5564495	46669029	Rat
8693635	Alc28	Alcohol consumption QTL 28	2.7	0.439	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	12	23081340	44726024	Rat
7411641	Foco19	Food consumption QTL 19	27.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	5564495	46669029	Rat
7411643	Foco20	Food consumption QTL 20		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	20328819	46669029	Rat
61324	Eae5	Experimental allergic encephalomyelitis QTL 5	14		nervous system integrity trait (VT:0010566)	percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time (CMO:0001402)	12	19610870	46669029	Rat
5684888	Pia42	Pristane induced arthritis QTL 42			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	19610870	42828880	Rat
1549912	Bp268	Blood pressure QTL 268			arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	10	13182736	46669029	Rat
2302060	Pia37	Pristane induced arthritis QTL 37	6.1	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	12	13198157	46669029	Rat
9590147	Scort7	Serum corticosterone level QTL 7	13.61	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	12	1	42110980	Rat
1641928	Alcrsp5	Alcohol response QTL 5			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	12	12812385	46669029	Rat
1300162	Bp188	Blood pressure QTL 188	3.19		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	32103174	45899022	Rat
8552912	Pigfal6	Plasma insulin-like growth factor 1 level QTL 6	5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	5564498	46669029	Rat
1549829	Scl48	Serum cholesterol level QTL 48	5		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	12	9603277	46669029	Rat
10059594	Kidm46	Kidney mass QTL 46	3.79	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	12	6107579	46669029	Rat
9590086	Insglur6	Insulin/glucose ratio QTL 6	18.97	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	12	1	42110980	Rat
8552918	Pigfal7	Plasma insulin-like growth factor 1 level QTL 7			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	5564495	46669029	Rat
1549902	Bp269	Blood pressure QTL 269			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	13182736	46669029	Rat
1600386	Calcic2	Intracellular calcium level QTL 2		0.001	platelet physiology trait (VT:0005464)	platelet intracellular calcium level (CMO:0000922)	12	28064433	46669029	Rat
1302792	Scl21	Serum cholesterol level QTL 21	3.8	0.0011	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	12	7196730	46669029	Rat
61404	Bw120	Body weight QTL 120	5.1		body mass (VT:0001259)	body mass index (BMI) (CMO:0000105)	12	12351619	46669029	Rat
1300175	Cm5	Cardiac mass QTL 5	3.78		heart mass (VT:0007028)	heart left ventricle weight to body weight ratio (CMO:0000530)	12	28064433	45899022	Rat
8693658	Alc33	Alcohol consumption QTL 33	2.1	0.68	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	12	23081340	43551788	Rat
2293699	Bss49	Bone structure and strength QTL 49	5.61	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	12	10474137	46669029	Rat
1331761	Bp218	Blood pressure QTL 218	2.973		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	11073825	45055165	Rat
634351	Apr5	Acute phase response QTL 5	6.7		blood interleukin-6 amount (VT:0008595)	plasma interleukin-6 level (CMO:0001927)	12	1	44503507	Rat
8694179	Bw150	Body weight QTL 150	2.9	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	12	1	42110980	Rat
634350	Apr4	Acute phase response QTL 4	6		orosomucoid 1 amount (VT:0010541)	plasma orosomucoid 1 level (CMO:0001467)	12	1172005	46172005	Rat
7411545	Bw128	Body weight QTL 128	5.2	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	12	1	42110980	Rat
7411547	Bw129	Body weight QTL 129		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	6	5564495	46669029	Rat
737979	Pia22	Pristane induced arthritis QTL 22	53.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	1	44465750	Rat
2303569	Gluco44	Glucose level QTL 44	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	12812385	46669029	Rat
7411586	Foco5	Food consumption QTL 5	5.4	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	1	42110980	Rat
2303575	Insul14	Insulin level QTL 14	4		blood insulin amount (VT:0001560)	blood insulin level (CMO:0000349)	12	1	42450532	Rat
7411588	Foco6	Food consumption QTL 6		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	5564495	46669029	Rat
2302042	Pia38	Pristane induced arthritis QTL 38	3.5	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	12	1	44503507	Rat
2300186	Bmd59	Bone mineral density QTL 59	7.1	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	12	10474137	46669029	Rat
7411595	Foco9	Food consumption QTL 9	4	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	1	42110980	Rat
7411597	Foco10	Food consumption QTL 10		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	5564495	46669029	Rat
7411660	Foco28	Food consumption QTL 28	10.9	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	1	42110980	Rat

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
6	11	17	24	45	48	27	17	27	6	104	50	11	13	24	21


RefSeq Transcripts	NM_001398920	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_001080179	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008760645	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_339593	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_595368	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BI296440	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CB585279	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473973	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000083569 ⟹ ENSRNOP00000073438

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	12	40,528,499 - 40,578,608 (+)	Ensembl
Rnor_6.0 Ensembl	12	46,257,343 - 46,287,546 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000099782 ⟹ ENSRNOP00000081727

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	12	40,528,499 - 40,570,115 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000106959 ⟹ ENSRNOP00000096289

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	12	40,528,502 - 40,570,115 (+)	Ensembl

RefSeq Acc Id:

NM_001398920 ⟹ NP_001385849

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	46,189,247 - 46,230,434 (+)	NCBI
mRatBN7.2	12	40,528,515 - 40,569,611 (+)	NCBI


Protein RefSeqs	NP_001385849	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM13849	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000073438
	ENSRNOP00000073438.2
	ENSRNOP00000081727.1
	ENSRNOP00000096289.1

Ensembl Acc Id:

ENSRNOP00000073438 ⟸ ENSRNOT00000083569

Ensembl Acc Id:

ENSRNOP00000096289 ⟸ ENSRNOT00000106959

Ensembl Acc Id:

ENSRNOP00000081727 ⟸ ENSRNOT00000099782

RefSeq Acc Id:	NP_001385849 ⟸ NM_001398920
- UniProtKB:	A6J1R0 (UniProtKB/TrEMBL), A0A8I6AT25 (UniProtKB/TrEMBL)

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A0G2K5I4-F1-model_v2	AlphaFold	A0A0G2K5I4	1-134	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-19027	BioCyc
Ensembl Genes	ENSRNOG00000053974	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000083569	ENTREZGENE
	ENSRNOT00000083569.2	UniProtKB/TrEMBL
	ENSRNOT00000099782.1	UniProtKB/TrEMBL
	ENSRNOT00000106959.1	UniProtKB/TrEMBL
InterPro	CD225/Dispanin	UniProtKB/TrEMBL
	CD225/Dispanin_fam	UniProtKB/TrEMBL
NCBI Gene	687797	ENTREZGENE
PANTHER	NG5	UniProtKB/TrEMBL
	TRANSMEMBRANE PROTEIN 233	UniProtKB/TrEMBL
Pfam	CD225	UniProtKB/TrEMBL
PhenoGen	Tmem233	PhenoGen
RatGTEx	ENSRNOG00000053974	RatGTEx
UniProt	A0A0G2K5I4_RAT	UniProtKB/TrEMBL
	A0A8I5ZTI1_RAT	UniProtKB/TrEMBL
	A0A8I6AT25	ENTREZGENE, UniProtKB/TrEMBL
	A6J1R0	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-06-08	Tmem233	transmembrane protein 233	LOC687797	similar to tumor suppressor candidate 5	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-11-20	LOC687797	similar to tumor suppressor candidate 5			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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