Tesc (tescalcin) - Rat Genome Database

Name: Tesc
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

	Submit Data \| Help \| Video Tutorials \| News \| Publications \| Download \| REST API \| Citing RGD \| Contact
	Search RGD Grant Resources Citing RGD About Us Contact Us Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer ACP Haplotyper Genome Scanner Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease Find Models new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive Pathways Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
	Advanced Search (OLGA)

Gene: Tesc (tescalcin) Rattus norvegicus

Analyze

Symbol:

Tesc

Name:

tescalcin

RGD ID:

1566317

Description:

Predicted to have metal ion binding activity; phosphatase inhibitor activity; and protein homodimerization activity. Predicted to be involved in several processes, including cellular response to retinoic acid; positive regulation of macromolecule metabolic process; and positive regulation of myeloid cell differentiation. Predicted to localize to several cellular components, including lamellipodium; nucleoplasm; and ruffle. Orthologous to human TESC (tescalcin); INTERACTS WITH 6-propyl-2-thiouracil; 7,12-dimethyltetraphene; bisphenol A.

Type:

protein-coding

RefSeq Status:

MODEL

Also known as:

calcineurin B homologous protein 3; LOC288689; RGD1566317; similar to Tescalcin

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TESC (tescalcin)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Tesc (tescalcin)	HGNC	Treefam, EggNOG, NCBI, OMA, HomoloGene, Inparanoid, Panther, PhylomeDB, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):	Tesc (tescalcin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TESC (tescalcin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TESC (tescalcin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Tesc (tescalcin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TESC (tescalcin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):	TESC (tescalcin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tesc (tescalcin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Tesc (tescalcin)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Homo sapiens (human):	TESC (tescalcin)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Danio rerio (zebrafish):	tesca (tescalcin a)	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Danio rerio (zebrafish):	tescb (tescalcin b)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Drosophila melanogaster (fruit fly):	CG14362	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PhylomeDB\|TreeFam)

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	12	38,521,839 - 38,555,665 (-)	NCBI
Rnor_6.0 Ensembl	12	44,141,422 - 44,174,583 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	12	44,141,258 - 44,174,701 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	12	45,972,890 - 46,006,329 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	12	39,669,706 - 39,704,041 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
Celera	12	40,180,191 - 40,225,489 (-)	NCBI		Celera
Cytogenetic Map	12	q16	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

3,3',5,5'-tetrabromobisphenol A (ISO)

4,4'-diaminodiphenylmethane (ISO)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

7,12-dimethyltetraphene (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

C60 fullerene (EXP)

carbon nanotube (ISO)

choline (ISO)

cisplatin (ISO)

cobalt dichloride (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

dibutyl phthalate (EXP)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

entinostat (ISO)

ethanol (ISO)

folic acid (ISO)

genistein (ISO)

ketamine (EXP)

L-methionine (ISO)

N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal (ISO)

nickel atom (ISO)

nicotinic acid (EXP)

PCB138 (ISO)

phenylmercury acetate (ISO)

pirinixic acid (ISO)

SB 431542 (ISO)

silicon dioxide (EXP,ISO)

sunitinib (ISO)

Tetrachlorobisphenol A (ISO)

titanium dioxide (EXP,ISO)

trichostatin A (ISO)

triclosan (ISO)

valproic acid (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to retinoic acid (ISO)

male gonad development (ISO)

megakaryocyte development (ISO)

megakaryocyte differentiation (ISO)

negative regulation of catalytic activity (IEA)

negative regulation of cell population proliferation (ISO,ISS)

positive regulation of gene expression (ISO,ISS)

positive regulation of granulocyte differentiation (ISO)

positive regulation of megakaryocyte differentiation (ISO,ISS)

positive regulation of sodium:proton antiporter activity (ISO)

positive regulation of transcription, DNA-templated (ISO,ISS)

protein localization to plasma membrane (ISO)

protein maturation (ISO)

protein stabilization (ISO)

regulation of cell adhesion mediated by integrin (ISO,ISS)

Cellular Component

cytoplasm (ISO)

cytosol (IEA,ISO)

lamellipodium (ISO,ISS)

nucleoplasm (IEA,ISO)

nucleus (ISO,ISS)

plasma membrane (ISO,ISS)

ruffle (ISO)

Molecular Function

calcium ion binding (ISO,ISS)

magnesium ion binding (ISO)

phosphatase inhibitor activity (ISO)

protein binding (ISO)

protein homodimerization activity (ISO)

References

References - curated


1.	RGD automated data pipeline
2.	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:11145610	PMID:11696366	PMID:14661968	PMID:17717601	PMID:18321853	PMID:19345287	PMID:20060826	PMID:21553168	PMID:22285131

Genomics

Comparative Map Data

Tesc
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	12	38,521,839 - 38,555,665 (-)	NCBI
Rnor_6.0 Ensembl	12	44,141,422 - 44,174,583 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	12	44,141,258 - 44,174,701 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	12	45,972,890 - 46,006,329 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	12	39,669,706 - 39,704,041 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
Celera	12	40,180,191 - 40,225,489 (-)	NCBI		Celera
Cytogenetic Map	12	q16	NCBI

TESC
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	12	117,038,923 - 117,099,479 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	12	117,038,923 - 117,099,490 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	12	117,476,728 - 117,537,221 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	115,961,111 - 116,021,634 (-)	NCBI	NCBI36		hg18	NCBI36
Celera	12	117,106,248 - 117,166,769 (-)	NCBI
Cytogenetic Map	12	q24.22	NCBI
HuRef	12	114,485,557 - 114,546,137 (-)	NCBI		HuRef
CHM1_1	12	117,444,429 - 117,505,233 (-)	NCBI		CHM1_1

Tesc
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	118,165,808 - 118,199,943 (+)	NCBI	GRCm39		mm39
GRCm39 Ensembl	5	118,165,808 - 118,199,943 (+)	Ensembl
GRCm38	5	118,027,743 - 118,061,878 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	118,027,743 - 118,061,878 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	118,477,833 - 118,511,879 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	5	118,288,854 - 118,322,900 (+)	NCBI			mm8
Celera	5	115,122,941 - 115,156,704 (+)	NCBI		Celera
Cytogenetic Map	5	F	NCBI
cM Map	5	57.84	NCBI

Tesc
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955455	14,053,443 - 14,092,637 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955455	14,053,918 - 14,092,637 (+)	NCBI	ChiLan1.0	ChiLan1.0

TESC
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	12	117,991,047 - 118,051,370 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	117,991,047 - 118,051,346 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	12	114,615,155 - 114,675,932 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

TESC
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	26	13,645,511 - 13,689,367 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	26	13,645,513 - 13,700,521 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Tesc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936558	5,397,018 - 5,417,335 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TESC
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	35,381,918 - 35,452,207 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	35,381,899 - 35,452,215 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	37,601,263 - 37,658,113 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TESC
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	112,331,123 - 112,410,901 (-)	NCBI
ChlSab1.1 Ensembl	11	112,327,906 - 112,410,849 (-)	Ensembl

Tesc
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624747	16,189,032 - 16,228,211 (+)	NCBI

Position Markers

RH128260

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	12	44,244,749 - 44,244,962	NCBI	Rnor6.0
Rnor_5.0	12	46,075,312 - 46,075,525	UniSTS	Rnor5.0
RGSC_v3.4	12	39,719,946 - 39,720,159	UniSTS	RGSC3.4
Celera	12	40,229,333 - 40,229,546	UniSTS
RH 3.4 Map	12	707.9	UniSTS
Cytogenetic Map	12	q16	UniSTS

AU048529

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	12	44,237,215 - 44,237,440	NCBI	Rnor6.0
Rnor_5.0	12	46,067,778 - 46,068,003	UniSTS	Rnor5.0
RGSC_v3.4	12	39,712,412 - 39,712,637	UniSTS	RGSC3.4
Celera	12	40,221,800 - 40,222,025	UniSTS
Cytogenetic Map	12	q16	UniSTS

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
9590086	Insglur6	Insulin/glucose ratio QTL 6	18.97	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	12	150810	45150810	Rat
9590147	Scort7	Serum corticosterone level QTL 7	13.61	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	12	150810	45150810	Rat
7411545	Bw128	Body weight QTL 128	5.2	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	12	150810	45150810	Rat
7411586	Foco5	Food consumption QTL 5	5.4	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	150810	45150810	Rat
7411660	Foco28	Food consumption QTL 28	10.9	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	150810	45150810	Rat
7411595	Foco9	Food consumption QTL 9	4	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	150810	45150810	Rat
8694179	Bw150	Body weight QTL 150	2.9	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	12	150810	45150810	Rat
2303575	Insul14	Insulin level QTL 14	4		blood insulin amount (VT:0001560)	blood insulin level (CMO:0000349)	12	492578	45492578	Rat
737979	Pia22	Pristane induced arthritis QTL 22	53.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	2475687	47475687	Rat
634351	Apr5	Acute phase response QTL 5	6.7		blood interleukin-6 amount (VT:0008595)	plasma interleukin-6 level (CMO:0001927)	12	2513442	47513442	Rat
2302042	Pia38	Pristane induced arthritis QTL 38	3.5	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	12	2513442	47513442	Rat
634350	Apr4	Acute phase response QTL 4	6		orosomucoid 1 amount (VT:0010541)	plasma orosomucoid 1 level (CMO:0001467)	12	4210051	49210051	Rat
7411547	Bw129	Body weight QTL 129		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	6	9223626	52716770	Rat
7411588	Foco6	Food consumption QTL 6		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	9223626	52716770	Rat
7411597	Foco10	Food consumption QTL 10		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	9223626	52716770	Rat
7411641	Foco19	Food consumption QTL 19	27.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	9223626	52716770	Rat
8552918	Pigfal7	Plasma insulin-like growth factor 1 level QTL 7			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	9223626	52716770	Rat
8552964	Pigfal17	Plasma insulin-like growth factor 1 level QTL 17	3.5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	9223626	52716770	Rat
8552912	Pigfal6	Plasma insulin-like growth factor 1 level QTL 6	5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	9223630	52716770	Rat
10059594	Kidm46	Kidney mass QTL 46	3.79	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	12	9789834	52716770	Rat
1331761	Bp218	Blood pressure QTL 218	2.973		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	13127211	50320041	Rat
61404	Bw120	Body weight QTL 120	5.1		body mass (VT:0001259)	body mass index (BMI) (CMO:0000105)	12	14419775	52716770	Rat
1549829	Scl48	Serum cholesterol level QTL 48	5		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	12	15021986	52716770	Rat
2300186	Bmd59	Bone mineral density QTL 59	7.1	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	12	15908900	52716770	Rat
2293699	Bss49	Bone structure and strength QTL 49	5.61	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	12	15908900	52716770	Rat
1641928	Alcrsp5	Alcohol response QTL 5			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	12	18342477	52716770	Rat
2303569	Gluco44	Glucose level QTL 44	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	18342477	52716770	Rat
2302060	Pia37	Pristane induced arthritis QTL 37	6.1	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	12	18729043	52716770	Rat
1549902	Bp269	Blood pressure QTL 269			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	18752593	52716770	Rat
1549912	Bp268	Blood pressure QTL 268			arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	10	18752593	52716770	Rat
737822	Alc10	Alcohol consumption QTL 10	2.2		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	12	22650702	45946937	Rat
5684888	Pia42	Pristane induced arthritis QTL 42			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	22650702	48598906	Rat
61324	Eae5	Experimental allergic encephalomyelitis QTL 5	14		nervous system integrity trait (VT:0010566)	percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time (CMO:0001402)	12	22650702	52716770	Rat
631560	Apr1	Acute phase response QTL 1	6.1		orosomucoid 1 amount (VT:0010541)	plasma orosomucoid 1 level (CMO:0001467)	12	24906590	52716770	Rat
7411643	Foco20	Food consumption QTL 20		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	26098845	52716770	Rat
8693658	Alc33	Alcohol consumption QTL 33	2.1	0.68	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	12	29113609	49560679	Rat
8693635	Alc28	Alcohol consumption QTL 28	2.7	0.439	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	12	29113609	50757185	Rat
1556747	Calcic1	Intracellular calcium level QTL 1		3.6	platelet calcium amount (VT:0010500)	platelet intracellular calcium level (CMO:0000922)	12	31723565	47433663	Rat
1300175	Cm5	Cardiac mass QTL 5	3.78		heart mass (VT:0007028)	heart left ventricle weight to body weight ratio (CMO:0000530)	12	31723565	51955754	Rat
1600386	Calcic2	Intracellular calcium level QTL 2		0.001	platelet physiology trait (VT:0005464)	platelet intracellular calcium level (CMO:0000922)	12	31723565	52716770	Rat
1331787	Rf41	Renal function QTL 41	2.998		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	12	31723688	45946802	Rat
1300162	Bp188	Blood pressure QTL 188	3.19		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	37521884	51955754	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	168
Count of miRNA genes:	144
Interacting mature miRNAs:	161
Transcripts:	ENSRNOT00000001490
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	2	43	14		17				31	23	21	9
Low	1		34	32	2	32	8	11	41	12	20	2	8
Below cutoff			7	7		7			2

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_006249426	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039090179	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039090180	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039090181	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_213790	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473973	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000229	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000001490 ⟹ ENSRNOP00000001490

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	12	44,141,422 - 44,174,583 (-)	Ensembl

RefSeq Acc Id:

XM_006249426 ⟹ XP_006249488

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	12	38,521,839 - 38,555,665 (-)	NCBI
Rnor_6.0	12	44,141,258 - 44,174,701 (-)	NCBI
Rnor_5.0	12	45,972,890 - 46,006,329 (-)	NCBI

Sequence:

show sequence

CGAGCCCCACGCGGAACCGGCTCCGTGCCGCTGTCCCCGCGTCTCCACCGGGCTCGAGCTCAGC
GCAGCCCAGGCAGTCCCCGTCCTGCGTGGGGCGCCCGGGGCCCCGCGGCGCACCATGGGCGCTG
CCCACTCGGCGTCCGAGGAGGTGCGGGAGCTCGAGGGCAAGACCGGTTTCTCCTCGGACCAGAT
AGAGCAACTGCACCGGAGGTTCAAGCAGCTAAGCGGAGACCAGCCCACCATTCGACTCTGCAGC
TCTCGTCTCTGCAGTGTGAGGAGTGTGAGTGTGCCACCCACCTCTCAGCTTCCTCTAAGTGTCA
AGCTCCAGTGGCGCCCAGTCTGTAGCAAGGAGAACTTTAACAATGTACCTGACCTGGAGCTCAA
CCCGATCCGATCCAAAATCGTCCGTGCCTTCTTCGACAACAGGAACCTGCGTAAGGGGTCCAGC
GGCCTGGCCGATGAGATCAACTTCGAGGACTTCCTGACTATCATGTCCTACTTCCGGCCCATTG
ACACTACCCTGGGTGAGGAACAAGTGGAGCTGTCTCGGAAGGAGAAGCTGAAATTTCTGTTCCA
TATGTATGACTCGGACAGTGACGGCCGCATCACCCTGGAAGAGTATCGAAATGTGGTGGAGGAA
CTGCTCTCTGGAAATCCTCACATCGAGAAGGAGTCAGCTCGGTCCATCGCCGACGGAGCCATGA
TGGAGGCTGCCAGCGTGTGCGTGGGACAGATGGAACCGGACCAGGTGTACGAGGGGATCACCTT
TGAGGACTTCCTGAAGATCTGGCAGGGCATCGACATCGAGACCAAGATGCACATCCGCTTCCTC
AACATGGAGACCATTGCCCTCTGCCACTGATCGTGCAGGGGAGGGGGTGGCTAAGGACCGAGGT
TCAGCCCTTTGTCTGGGCTGCTGTGACAATCAGTAACCCTTCAGTTAGCCTCCTTGTGTGGTGT
GGCGTGTGGGACTCCGATGTTTTTATCTCTAATGGTGACAATAAAGGTTTCCTAATGAGCCCGG
CA

hide sequence

RefSeq Acc Id:

XM_017604544 ⟹ XP_017460033

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Celera	12	40,180,191 - 40,225,489 (-)	NCBI

Sequence:

show sequence

ATGCATTCAGTCAGTGCTGCAGGCCAGGACCGCGCCGCTCCGCCTCCCGCCGCTATAAGAGGCC
GCTCGAGCCCCACGCGGAACCGGCTCCGTGCCGCTGTCCCCGCGTCTCCACCGGGCTCGAGCTC
AGCGCAGCCCAGGCAGTCCCCGTCCTGCGTGGGGCGCCCGGGGCCCCGCGGCGCACCATGGGCG
CTGCCCACTCGGCGTCCGAGGAGGTGCGGGAGCTCGAGGGCAAGACCGGTTTCTCCTCGGGACC
AGATAGAGCAACTGCACCGGAGGTTCAAGCAGCTAAGCGGAGACCAGCCCACCATTCGACTCTG
CAGCTCTCGTCTCTGCAGTGTGAGGAGTGTGAGTGTGCCACCCACCTCTCAGCTTCCTCTAAGT
GTCAAGCTCCAGTGGCGCCCAGTCTGTAGCAAGGAGAACTTTAACAATGTACCTGACCTGGAGC
TCAACCCGATCCGATCCAAAATCGTCCGTGCCTTCTTCGACAACAGGAACCTGCGTAAGGGGTC
CAGCGGCCTGGCCGATGAGATCAACTTCGAGGACTTCCTGACTATCATGTCCTACTTCCGGCCC
ATTGACACTACCCTGGGTGAGGAACAAGTGGAGCTGTCTCGGAAGGAGAAGCTGAAATTTCTGT
TCCATATGTATGACTCGGACAGTGACGGCCGCATCACCCTGGAAGAGTATCGAAATGTGGTGGA
GGAACTGCTCTCTGGAAATCCTCACATCGAGAAGGAGTCAGCTCGGTCCATCGCCGACGGAGCC
ATGATGGAGGCTGCCAGCGTGTGCGTGGGACAGATGGAACCGGACCAGGTGTACGAGGGGATCA
CCTTTGAGGACTTCCTGAAGATCTGGCAGGGCATCGACATCGAGACCAAGATGCACATCCGCTT
CCTCAACATGGAGACCATTGCCCTCTGCCACTGATCGTGCAGGGGAGGGGGTGGCTAAGGACCG
AGGTTCAGCCCTTTGTCTGGGCTGCTGTGACAATCAGTAACCCTTCAGTTAGCCTCCTTGTGTG
GTGTGGCGTGTGGGACTCCGATGTTTTTATCTCTAATGGTGACAATAAAGGTTTCCTAATGAGC
CCGGCA

hide sequence

RefSeq Acc Id:

XM_039090179 ⟹ XP_038946107

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	12	38,521,840 - 38,537,968 (-)	NCBI

RefSeq Acc Id:

XM_039090180 ⟹ XP_038946108

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	12	38,521,840 - 38,537,968 (-)	NCBI

RefSeq Acc Id:

XM_039090181 ⟹ XP_038946109

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	12	38,521,840 - 38,537,730 (-)	NCBI

RefSeq Acc Id:

XM_213790 ⟹ XP_213790

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	12	38,521,840 - 38,555,662 (-)	NCBI
Rnor_6.0	12	44,141,258 - 44,174,698 (-)	NCBI
Rnor_5.0	12	45,972,890 - 46,006,329 (-)	NCBI
RGSC_v3.4	12	39,669,706 - 39,704,041 (-)	RGD

Sequence:

show sequence

GCCCCACGCGGAACCGGCTCCGTGCCGCTGTCCCCGCGTCTCCACCGGGCTCGAGCTCAGCGCA
GCCCAGGCAGTCCCCGTCCTGCGTGGGGCGCCCGGGGCCCCGCGGCGCACCATGGGCGCTGCCC
ACTCGGCGTCCGAGGAGGTGCGGGAGCTCGAGGGCAAGACCGGTTTCTCCTCGGACCAGATAGA
GCAACTGCACCGGAGGTTCAAGCAGCTAAGCGGAGACCAGCCCACCATTCGCAAGGAGAACTTT
AACAATGTACCTGACCTGGAGCTCAACCCGATCCGATCCAAAATCGTCCGTGCCTTCTTCGACA
ACAGGAACCTGCGTAAGGGGTCCAGCGGCCTGGCCGATGAGATCAACTTCGAGGACTTCCTGAC
TATCATGTCCTACTTCCGGCCCATTGACACTACCCTGGGTGAGGAACAAGTGGAGCTGTCTCGG
AAGGAGAAGCTGAAATTTCTGTTCCATATGTATGACTCGGACAGTGACGGCCGCATCACCCTGG
AAGAGTATCGAAATGTGGTGGAGGAACTGCTCTCTGGAAATCCTCACATCGAGAAGGAGTCAGC
TCGGTCCATCGCCGACGGAGCCATGATGGAGGCTGCCAGCGTGTGCGTGGGACAGATGGAACCG
GACCAGGTGTACGAGGGGATCACCTTTGAGGACTTCCTGAAGATCTGGCAGGGCATCGACATCG
AGACCAAGATGCACATCCGCTTCCTCAACATGGAGACCATTGCCCTCTGCCACTGATCGTGCAG
GGGAGGGGGTGGCTAAGGACCGAGGTTCAGCCCTTTGTCTGGGCTGCTGTGACAATCAGTAACC
CTTCAGTTAGCCTCCTTGTGTGGTGTGGCGTGTGGGACTCCGATGTTTTTATCTCTAATGGTGA
CAATAAAGGTTTCCTAATGAGCCCGGCA

hide sequence

Protein Sequences


Protein RefSeqs	XP_006249488	(Get FASTA)	NCBI Sequence Viewer
	XP_038946107	(Get FASTA)	NCBI Sequence Viewer
	XP_038946108	(Get FASTA)	NCBI Sequence Viewer
	XP_038946109	(Get FASTA)	NCBI Sequence Viewer
	XP_213790	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM13813	(Get FASTA)	NCBI Sequence Viewer
	EDM13814	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	XP_213790 ⟸ XM_213790
- Peptide Label:	isoform X3
- UniProtKB:	D3ZTN1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGAAHSASEEVRELEGKTGFSSDQIEQLHRRFKQLSGDQPTIRKENFNNVPDLELNPIRSKIVR AFFDNRNLRKGSSGLADEINFEDFLTIMSYFRPIDTTLGEEQVELSRKEKLKFLFHMYDSDSDG RITLEEYRNVVEELLSGNPHIEKESARSIADGAMMEAASVCVGQMEPDQVYEGITFEDFLKIWQ GIDIETKMHIRFLNMETIALCH hide sequence

RefSeq Acc Id:

XP_006249488 ⟸ XM_006249426

- Peptide Label:

isoform X1

- Sequence:

show sequence

MGAAHSASEEVRELEGKTGFSSDQIEQLHRRFKQLSGDQPTIRLCSSRLCSVRSVSVPPTSQLP
LSVKLQWRPVCSKENFNNVPDLELNPIRSKIVRAFFDNRNLRKGSSGLADEINFEDFLTIMSYF
RPIDTTLGEEQVELSRKEKLKFLFHMYDSDSDGRITLEEYRNVVEELLSGNPHIEKESARSIAD
GAMMEAASVCVGQMEPDQVYEGITFEDFLKIWQGIDIETKMHIRFLNMETIALCH

hide sequence

RefSeq Acc Id:

XP_017460033 ⟸ XM_017604544

- Peptide Label:

isoform X3

- Sequence:

show sequence

MHSVSAAGQDRAAPPPAAIRGRSSPTRNRLRAAVPASPPGSSSAQPRQSPSCVGRPGPRGAPWA
LPTRRPRRCGSSRARPVSPRDQIEQLHRRFKQLSGDQPTIRLCSSRLCSVRSVSVPPTSQLPLS
VKLQWRPVCSKENFNNVPDLELNPIRSKIVRAFFDNRNLRKGSSGLADEINFEDFLTIMSYFRP
IDTTLGEEQVELSRKEKLKFLFHMYDSDSDGRITLEEYRNVVEELLSGNPHIEKESARSIADGA
MMEAASVCVGQMEPDQVYEGITFEDFLKIWQGIDIETKMHIRFLNMETIALCH

hide sequence

RefSeq Acc Id:

ENSRNOP00000001490 ⟸ ENSRNOT00000001490

RefSeq Acc Id:	XP_038946108 ⟸ XM_039090180
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038946107 ⟸ XM_039090179
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038946109 ⟸ XM_039090181
- Peptide Label:	isoform X5

Protein Domains

EF-hand

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN/SsN (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Buf/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

F344/NCrl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

FHH/EurMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

GH/OmrMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/Ox (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LE/Stm (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

M520/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MHS/Gib (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

SBH/Ygl (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHRSP/Gcrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/Gcrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1566317	AgrOrtholog
Ensembl Genes	ENSRNOG00000001128	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000001490	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000001490	UniProtKB/TrEMBL
InterPro	EF-hand-like_dom	UniProtKB/TrEMBL
	EF_Hand_1_Ca_BS	UniProtKB/TrEMBL
	EF_hand_Ca-bd	UniProtKB/TrEMBL
NCBI Gene	288689	ENTREZGENE
PhenoGen	Tesc	PhenoGen
PROSITE	EF_HAND_1	UniProtKB/TrEMBL
	EF_HAND_2	UniProtKB/TrEMBL
SMART	EFh	UniProtKB/TrEMBL
Superfamily-SCOP	SSF47473	UniProtKB/TrEMBL
UniProt	D3ZTN1	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-07	Tesc	tescalcin	RGD1566317_predicted	similar to Tescalcin (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-07	RGD1566317_predicted	similar to Tescalcin (predicted)	LOC288689	similar to Tescalcin	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC288689	similar to Tescalcin			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)