Cox6a1 (cytochrome c oxidase subunit 6A1) - Rat Genome Database

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Gene: Cox6a1 (cytochrome c oxidase subunit 6A1) Rattus norvegicus
Analyze
Symbol: Cox6a1
Name: cytochrome c oxidase subunit 6A1
RGD ID: 2384
Description: Predicted to enable enzyme regulator activity. Predicted to be involved in mitochondrial electron transport, cytochrome c to oxygen. Predicted to be located in mitochondrial membrane. Predicted to be part of mitochondrial respiratory chain complex IV. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease recessive intermediate D. Orthologous to human COX6A1 (cytochrome c oxidase subunit 6A1); PARTICIPATES IN Alzheimer's disease pathway; Huntington's disease pathway; oxidative phosphorylation pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: COX6AL; cytochrome c oxidase polypeptide VIa-liver; cytochrome c oxidase subunit 6A1, mitochondrial; Cytochrome c oxidase subunit VIa (liver); cytochrome c oxidase, subunit VIa, polypeptide 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81246,922,709 - 46,925,762 (+)NCBIGRCr8
mRatBN7.21241,261,983 - 41,265,037 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1241,261,967 - 41,265,041 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1242,428,777 - 42,431,826 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01243,042,446 - 43,045,495 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01242,102,998 - 42,106,047 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01247,024,442 - 47,027,495 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1247,024,442 - 47,027,495 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01248,817,758 - 48,820,811 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41242,530,091 - 42,533,144 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11242,393,577 - 42,396,520 (+)NCBI
Celera1242,883,040 - 42,886,093 (+)NCBICelera
Cytogenetic Map12q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-hydroxypropanoic acid  (ISO)
5-Hydroxythalidomide  (ISO)
6-propyl-2-thiouracil  (EXP)
amitrole  (EXP)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
capsaicin  (EXP)
carbon nanotube  (ISO)
carnosic acid  (ISO)
chloropicrin  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
cisplatin  (ISO)
clobetasol  (ISO)
clofibrate  (ISO)
cocaine  (EXP)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) chloride  (ISO)
dibutyl phthalate  (EXP)
doxorubicin  (EXP,ISO)
elemental selenium  (ISO)
ethanol  (ISO)
fenthion  (ISO)
flavonoids  (EXP)
folic acid  (ISO)
isoniazide  (ISO)
isotretinoin  (ISO)
L-methionine  (ISO)
lamivudine  (ISO)
lipopolysaccharide  (ISO)
maneb  (ISO)
Mesaconitine  (EXP)
methidathion  (ISO)
methimazole  (EXP)
methotrexate  (ISO)
N,N-diethyl-m-toluamide  (EXP)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
permethrin  (EXP)
phorbol 13-acetate 12-myristate  (ISO)
pirinixic acid  (ISO)
propiconazole  (EXP)
Pyridostigmine bromide  (EXP)
rac-lactic acid  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
sarin  (EXP,ISO)
selenium atom  (ISO)
sulfadimethoxine  (EXP)
tetrachloroethene  (ISO)
toluene  (EXP)
Tributyltin oxide  (EXP,ISO)
tungsten  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)
zidovudine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Structural organisation of the rat genes encoding liver- and heart-type of cytochrome c oxidase subunit VIa and a pseudogene related to the COXVIa-L cDNA. Mell OC, etal., Gene 1994 Mar 25;140(2):179-86.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Characterization of two different genes (cDNA) for cytochrome c oxidase subunit VIa from heart and liver of the rat. Schlerf A, etal., EMBO J 1988 Aug;7(8):2387-91.
9. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:2153407   PMID:7601105   PMID:7667285   PMID:14651853   PMID:17634366   PMID:18614015   PMID:30030519  


Genomics

Comparative Map Data
Cox6a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81246,922,709 - 46,925,762 (+)NCBIGRCr8
mRatBN7.21241,261,983 - 41,265,037 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1241,261,967 - 41,265,041 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1242,428,777 - 42,431,826 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01243,042,446 - 43,045,495 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01242,102,998 - 42,106,047 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01247,024,442 - 47,027,495 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1247,024,442 - 47,027,495 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01248,817,758 - 48,820,811 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41242,530,091 - 42,533,144 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11242,393,577 - 42,396,520 (+)NCBI
Celera1242,883,040 - 42,886,093 (+)NCBICelera
Cytogenetic Map12q16NCBI
COX6A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812120,438,113 - 120,440,730 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12120,438,090 - 120,440,737 (+)EnsemblGRCh38hg38GRCh38
GRCh3712120,875,916 - 120,878,533 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612119,360,287 - 119,362,915 (+)NCBINCBI36Build 36hg18NCBI36
Build 3412119,338,623 - 119,341,249NCBI
Celera12120,509,797 - 120,512,425 (+)NCBICelera
Cytogenetic Map12q24.31NCBI
HuRef12117,884,248 - 117,886,900 (+)NCBIHuRef
CHM1_112120,843,826 - 120,846,454 (+)NCBICHM1_1
T2T-CHM13v2.012120,426,035 - 120,428,652 (+)NCBIT2T-CHM13v2.0
Cox6a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395115,483,711 - 115,487,017 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5115,483,701 - 115,487,040 (-)EnsemblGRCm39 Ensembl
GRCm385115,345,652 - 115,348,958 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5115,345,642 - 115,348,981 (-)EnsemblGRCm38mm10GRCm38
MGSCv375115,795,663 - 115,798,964 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365115,606,653 - 115,609,954 (-)NCBIMGSCv36mm8
Celera5112,442,908 - 112,446,212 (-)NCBICelera
Cytogenetic Map5FNCBI
cM Map556.06NCBI
LOC102012060
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545511,201,031 - 11,203,748 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545511,201,031 - 11,203,644 (-)NCBIChiLan1.0ChiLan1.0
LOC103783978
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210128,505,992 - 128,508,818 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112128,502,370 - 128,505,198 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012118,019,493 - 118,022,152 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112121,393,898 - 121,396,561 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12121,393,917 - 121,396,561 (+)Ensemblpanpan1.1panPan2
LOC477508
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12616,346,760 - 16,349,042 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2616,350,243 - 16,352,647 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02616,613,800 - 16,616,205 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12616,573,854 - 16,576,262 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02616,650,575 - 16,652,975 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02616,692,407 - 16,694,812 (+)NCBIUU_Cfam_GSD_1.0
LOC101954852
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118146,007,358 - 146,009,791 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936668506,242 - 509,409 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936668506,242 - 508,658 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
COX6A1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1440,408,631 - 40,412,870 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11440,408,600 - 40,410,810 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21442,876,318 - 42,878,528 (+)NCBISscrofa10.2Sscrofa10.2susScr3
COX6A1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111115,792,822 - 115,795,368 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11115,792,622 - 115,796,488 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037129,304,757 - 129,307,460 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LOC101698437
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474713,227,169 - 13,230,271 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cox6a1
2 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:146
Count of miRNA genes:104
Interacting mature miRNAs:110
Transcripts:ENSRNOT00000001545
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411660Foco28Food consumption QTL 2810.90.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
9590086Insglur6Insulin/glucose ratio QTL 618.970.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)12142110980Rat
8694179Bw150Body weight QTL 1502.90.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
7411586Foco5Food consumption QTL 55.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411595Foco9Food consumption QTL 940.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411545Bw128Body weight QTL 1285.20.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)12142110980Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12142450532Rat
737979Pia22Pristane induced arthritis QTL 2253.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12144465750Rat
634351Apr5Acute phase response QTL 56.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)12144503507Rat
2302042Pia38Pristane induced arthritis QTL 383.50.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)12144503507Rat
634350Apr4Acute phase response QTL 46orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)12117200546172005Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)6556449546669029Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449846669029Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)12610757946669029Rat
1302792Scl21Serum cholesterol level QTL 213.80.0011blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)12719673046669029Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)12960327746669029Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121047413746669029Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121047413746669029Rat
1331761Bp218Blood pressure QTL 2182.973arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121107382545055165Rat
61404Bw120Body weight QTL 1205.1body mass (VT:0001259)body mass index (BMI) (CMO:0000105)121235161946669029Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121281238546669029Rat
2303569Gluco44Glucose level QTL 442blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121281238546669029Rat
1549902Bp269Blood pressure QTL 269arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)121318273646669029Rat
1549912Bp268Blood pressure QTL 268arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)101318273646669029Rat
2302060Pia37Pristane induced arthritis QTL 376.10.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)121319815746669029Rat
631560Apr1Acute phase response QTL 16.1orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)121914436246669029Rat
5684888Pia42Pristane induced arthritis QTL 42joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)121961087042828880Rat
61324Eae5Experimental allergic encephalomyelitis QTL 514nervous system integrity trait (VT:0010566)percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time (CMO:0001402)121961087046669029Rat
7411643Foco20Food consumption QTL 200.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)122032881946669029Rat
1300175Cm5Cardiac mass QTL 53.78heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)122806443345899022Rat
1600386Calcic2Intracellular calcium level QTL 20.001platelet physiology trait (VT:0005464)platelet intracellular calcium level (CMO:0000922)122806443346669029Rat
1300162Bp188Blood pressure QTL 1883.19arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)123210317445899022Rat

Markers in Region
RH127421  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21241,264,795 - 41,264,992 (+)MAPPERmRatBN7.2
Rnor_6.01247,027,254 - 47,027,450NCBIRnor6.0
Rnor_5.01248,820,570 - 48,820,766UniSTSRnor5.0
RGSC_v3.41242,532,903 - 42,533,099UniSTSRGSC3.4
Celera1242,885,852 - 42,886,048UniSTS
Cytogenetic Map12q16UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 1 10 1 3
Medium 2 33 57 41 19 41 8 11 73 32 41 11 8
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000001545   ⟹   ENSRNOP00000001545
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1241,261,967 - 41,265,041 (+)Ensembl
Rnor_6.0 Ensembl1247,024,442 - 47,027,495 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000117053   ⟹   ENSRNOP00000078588
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1241,261,967 - 41,263,215 (+)Ensembl
RefSeq Acc Id: NM_012814   ⟹   NP_036946
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81246,922,709 - 46,925,762 (+)NCBI
mRatBN7.21241,261,983 - 41,265,037 (+)NCBI
Rnor_6.01247,024,442 - 47,027,495 (+)NCBI
Rnor_5.01248,817,758 - 48,820,811 (+)NCBI
RGSC_v3.41242,530,091 - 42,533,144 (+)RGD
Celera1242,883,040 - 42,886,093 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_036946 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein CAA31067 (Get FASTA)   NCBI Sequence Viewer  
  CAA51286 (Get FASTA)   NCBI Sequence Viewer  
  EDM13886 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000001545
  ENSRNOP00000001545.4
  ENSRNOP00000078588.1
GenBank Protein P10818 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_036946   ⟸   NM_012814
- Peptide Label: precursor
- UniProtKB: P10818 (UniProtKB/Swiss-Prot),   A6J1U7 (UniProtKB/TrEMBL),   A0A8L2PZ08 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000001545   ⟸   ENSRNOT00000001545
RefSeq Acc Id: ENSRNOP00000078588   ⟸   ENSRNOT00000117053

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P10818-F1-model_v2 AlphaFold P10818 1-111 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698692
Promoter ID:EPDNEW_R9216
Type:multiple initiation site
Name:Cox6a1_1
Description:cytochrome c oxidase subunit 6A1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01247,024,455 - 47,024,515EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2384 AgrOrtholog
BioCyc Gene G2FUF-18988 BioCyc
BioCyc Pathway PWY-3781 [aerobic respiration I (cytochrome c)] BioCyc
  PWY-7279 [aerobic respiration II (cytochrome c) (yeast)] BioCyc
BioCyc Pathway Image PWY-3781 BioCyc
  PWY-7279 BioCyc
Ensembl Genes ENSRNOG00000001170 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000001545 ENTREZGENE
  ENSRNOT00000001545.5 UniProtKB/TrEMBL
  ENSRNOT00000117053.1 UniProtKB/TrEMBL
Gene3D-CATH 4.10.95.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Cyt_c_oxidase_su6a UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyt_c_oxidase_su6a_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyt_c_oxidase_su6a_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:25282 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 25282 ENTREZGENE
PANTHER CYTOCHROME C OXIDASE SUBUNIT 6A1, MITOCHONDRIAL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11504 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam COX6A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cox6a1 PhenoGen
PIRSF COX6A1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE COX6A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000001170 RatGTEx
Superfamily-SCOP SSF81411 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC228647
UniProt A0A8I5ZL99_RAT UniProtKB/TrEMBL
  A0A8L2PZ08 ENTREZGENE, UniProtKB/TrEMBL
  A6J1U7 ENTREZGENE, UniProtKB/TrEMBL
  CX6A1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-17 Cox6a1  cytochrome c oxidase subunit 6A1  Cox6a1  cytochrome c oxidase, subunit VIa, polypeptide 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-11-06 Cox6a1  cytochrome c oxidase, subunit VIa, polypeptide 1    Cytochrome c oxidase subunit VIa (liver)  Name updated 625702 APPROVED
2002-06-10 Cox6a1  Cytochrome c oxidase subunit VIa (liver)      Symbol and Name status set to approved 70586 APPROVED