1,2-dichloroethane increases expression ISO RGD:735797 6480464 ethylene dichloride results in increased expression of TRPV4 mRNA CTD PMID:28960355 17beta-estradiol multiple interactions ISO RGD:1604803 6480464 [Estradiol co-treated with TGFB1 protein] results in decreased expression of TRPV4 mRNA CTD PMID:30165855 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1604803 6480464 Tetrachlorodibenzodioxin affects the expression of TRPV4 mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:735797 6480464 Tetrachlorodibenzodioxin results in decreased expression of TRPV4 mRNA CTD PMID:33956508 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:735797 6480464 Tetrachlorodibenzodioxin results in increased expression of TRPV4 mRNA CTD PMID:26290441 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:735797 6480464 Tetrachlorodibenzodioxin affects the expression of TRPV4 mRNA CTD PMID:21570461 , PMID:26377647 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1604803 6480464 Tetrachlorodibenzodioxin results in increased expression of TRPV4 mRNA CTD PMID:20106945 , PMID:21632981 2,3,7,8-Tetrachlorodibenzofuran decreases expression EXP 6480464 2 more ... CTD PMID:32109520 2,4,6-trinitrobenzenesulfonic acid increases expression ISO RGD:735797 6480464 Trinitrobenzenesulfonic Acid results in increased expression of TRPV4 mRNA CTD PMID:22882778 2-amino-2-deoxy-D-glucopyranose increases expression ISO RGD:735797 6480464 Glucosamine results in increased expression of TRPV4 mRNA CTD PMID:17178593 3',5'-cyclic AMP increases expression EXP 6480464 Cyclic AMP results in increased expression of TRPV4 mRNA, Cyclic AMP results in increased expression of TRPV4 protein CTD PMID:22187434 3',5'-cyclic AMP multiple interactions EXP 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cyclic AMP results in increased expression of TRPV4 mRNA], 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cyclic AMP results in increased expression of TRPV4 protein] CTD PMID:22187434 3,4-methylenedioxymethamphetamine increases expression ISO RGD:735797 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in increased expression of TRPV4 mRNA CTD PMID:26251327 3-chloropropane-1,2-diol increases expression EXP 6480464 alpha-Chlorohydrin results in increased expression of TRPV4 mRNA CTD PMID:28522335 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:1604803 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of TRPV4 mRNA CTD PMID:28628672 3-methylcholanthrene multiple interactions ISO RGD:1604803 6480464 Methylcholanthrene promotes the reaction [AHR protein binds to TRPV4 promoter] CTD PMID:20348232 4,4'-sulfonyldiphenol multiple interactions ISO RGD:1604803 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of TRPV4 mRNA CTD PMID:28628672 4-hydroxynon-2-enal increases expression ISO RGD:735797 6480464 4-hydroxy-2-nonenal results in increased expression of TRPV4 mRNA CTD PMID:19191707 4-hydroxyphenyl retinamide increases expression ISO RGD:735797 6480464 Fenretinide results in increased expression of TRPV4 mRNA CTD PMID:28973697 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of TRPV4 mRNA CTD PMID:25825206 acrylamide decreases expression EXP 6480464 Acrylamide results in decreased expression of TRPV4 mRNA CTD PMID:28959563 aldehydo-D-glucosamine increases expression ISO RGD:735797 6480464 Glucosamine results in increased expression of TRPV4 mRNA CTD PMID:17178593 all-trans-retinoic acid increases expression ISO RGD:1604803 6480464 Tretinoin results in increased expression of TRPV4 mRNA CTD PMID:33167477 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of TRPV4 mRNA CTD PMID:16483693 arachidonic acid increases activity ISO RGD:1604803 6480464 Arachidonic Acid results in increased activity of TRPV4 protein CTD PMID:20956320 benzo[a]pyrene increases expression ISO RGD:735797 6480464 Benzo(a)pyrene results in increased expression of TRPV4 mRNA CTD PMID:27195522 benzo[a]pyrene affects methylation ISO RGD:1604803 6480464 Benzo(a)pyrene affects the methylation of TRPV4 5' UTR, Benzo(a)pyrene affects the methylation of TRPV4 promoter CTD PMID:27901495 benzo[a]pyrene increases methylation ISO RGD:1604803 6480464 Benzo(a)pyrene results in increased methylation of TRPV4 3' UTR CTD PMID:27901495 benzo[a]pyrene multiple interactions ISO RGD:735797 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of TRPV4 mRNA CTD PMID:27858113 benzo[b]fluoranthene increases expression ISO RGD:735797 6480464 benzo(b)fluoranthene results in increased expression of TRPV4 mRNA CTD PMID:26377693 benzo[b]fluoranthene multiple interactions ISO RGD:735797 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of TRPV4 mRNA CTD PMID:27858113 beta-D-glucosamine increases expression ISO RGD:735797 6480464 Glucosamine results in increased expression of TRPV4 mRNA CTD PMID:17178593 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of TRPV4 mRNA CTD PMID:25181051 bisphenol A multiple interactions ISO RGD:1604803 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of TRPV4 gene CTD PMID:31601247 bisphenol A increases methylation ISO RGD:735797 6480464 bisphenol A results in increased methylation of TRPV4 promoter CTD PMID:27312807 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of TRPV4 mRNA CTD PMID:30816183 calcium atom multiple interactions ISO RGD:1604803 6480464 TRPV4 protein promotes the reaction [phorbol-12, 13-didecanoate results in increased import of Calcium] CTD PMID:18355916 calcium atom multiple interactions ISO RGD:735797 6480464 TRPV4 protein promotes the reaction [ITGA2 protein promotes the reaction [[Dinoprostone co-treated with Serotonin] results in increased import of Calcium]] CTD PMID:18234883 calcium(0) multiple interactions ISO RGD:1604803 6480464 TRPV4 protein promotes the reaction [phorbol-12, 13-didecanoate results in increased import of Calcium] CTD PMID:18355916 calcium(0) multiple interactions ISO RGD:735797 6480464 TRPV4 protein promotes the reaction [ITGA2 protein promotes the reaction [[Dinoprostone co-treated with Serotonin] results in increased import of Calcium]] CTD PMID:18234883 Cannabichromene decreases expression ISO RGD:735797 6480464 cannabichromene results in decreased expression of TRPV4 mRNA CTD PMID:21726418 cannabidiol affects activity ISO RGD:1604803 6480464 Cannabidiol affects the activity of TRPV4 protein CTD PMID:33629929 Cannabidivarin increases activity EXP 6480464 cannabidivarin results in increased activity of TRPV4 protein CTD PMID:21726418 capsaicin increases expression EXP 6480464 Capsaicin results in increased expression of TRPV4 mRNA CTD PMID:16278290 choline multiple interactions ISO RGD:735797 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of TRPV4 mRNA CTD PMID:20938992 chrysene multiple interactions ISO RGD:735797 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of TRPV4 mRNA CTD PMID:27858113 Cuprizon increases expression EXP 6480464 Cuprizone results in increased expression of TRPV4 mRNA CTD PMID:26577399 cyclosporin A decreases expression ISO RGD:1604803 6480464 Cyclosporine results in decreased expression of TRPV4 mRNA CTD PMID:27989131 dexamethasone multiple interactions ISO RGD:1604803 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of TRPV4 mRNA CTD PMID:28628672 dextran sulfate multiple interactions ISO RGD:735797 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TRPV4 mRNA CTD PMID:29950665 dibenz[a,h]anthracene increases expression ISO RGD:735797 6480464 1 more ... CTD PMID:26377693 diuron increases expression EXP 6480464 Diuron results in increased expression of TRPV4 mRNA CTD PMID:21551480 ethanol multiple interactions EXP 6480464 Ethanol results in increased expression of [ITGA2 protein binds to LYN protein binds to TRPV4 protein] CTD PMID:18234883 ethanol increases response to substance EXP 6480464 TRPV4 protein results in increased susceptibility to Ethanol CTD PMID:18234883 fipronil decreases expression EXP 6480464 fipronil results in decreased expression of TRPV4 mRNA CTD PMID:23962444 flavonoids decreases expression EXP 6480464 Flavonoids results in decreased expression of TRPV4 mRNA CTD PMID:18035473 folic acid multiple interactions ISO RGD:735797 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of TRPV4 mRNA CTD PMID:20938992 fulvestrant multiple interactions ISO RGD:1604803 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of TRPV4 gene CTD PMID:31601247 furan increases expression EXP 6480464 furan results in increased expression of TRPV4 mRNA CTD PMID:27387713 gadolinium atom multiple interactions EXP 6480464 [Gadolinium results in decreased activity of TRPV4 protein] which results in decreased susceptibility to Buthionine Sulfoximine CTD PMID:20064552 gadolinium atom decreases activity EXP 6480464 Gadolinium results in decreased activity of TRPV4 protein CTD PMID:20064552 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of TRPV4 mRNA CTD PMID:22061828 gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of TRPV4 mRNA CTD PMID:33387578 glycidol increases expression EXP 6480464 glycidol results in increased expression of TRPV4 mRNA CTD PMID:24395379 icosanoid affects activity ISO RGD:1604803 6480464 Eicosanoids affects the activity of TRPV4 protein CTD PMID:19666518 Indeno[1,2,3-cd]pyrene decreases expression ISO RGD:735797 6480464 indeno(1 more ... CTD PMID:26377693 indometacin multiple interactions ISO RGD:1604803 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of TRPV4 mRNA CTD PMID:28628672 ionomycin increases activity EXP 6480464 Ionomycin results in increased activity of TRPV4 protein CTD PMID:21726418 ketamine multiple interactions EXP 6480464 TRPV4 protein affects the reaction [Ketamine results in decreased activity of CAT protein] more ... CTD PMID:33536391 ketamine increases expression EXP 6480464 Ketamine results in increased expression of TRPV4 mRNA, Ketamine results in increased expression of TRPV4 protein CTD PMID:33536391 L-methionine multiple interactions ISO RGD:735797 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of TRPV4 mRNA CTD PMID:20938992 lead diacetate affects expression EXP 6480464 lead acetate affects the expression of TRPV4 mRNA CTD PMID:21864555 lead diacetate decreases expression EXP 6480464 lead acetate results in decreased expression of TRPV4 mRNA CTD PMID:22641619 leflunomide increases expression ISO RGD:1604803 6480464 leflunomide results in increased expression of TRPV4 mRNA CTD PMID:28988120 ozone multiple interactions ISO RGD:735797 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of TRPV4 mRNA, [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of TRPV4 mRNA CTD PMID:34911549 paracetamol increases expression ISO RGD:1604803 6480464 Acetaminophen results in increased expression of TRPV4 mRNA CTD PMID:22230336 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of TRPV4 mRNA CTD PMID:33387578 paraquat decreases expression EXP 6480464 Paraquat results in decreased expression of TRPV4 mRNA CTD PMID:32680482 prostaglandin E2 multiple interactions ISO RGD:735797 6480464 TRPV4 protein promotes the reaction [ITGA2 protein promotes the reaction [[Dinoprostone co-treated with Serotonin] results in increased import of Calcium]] CTD PMID:18234883 ruthenium red multiple interactions EXP 6480464 [Ruthenium Red results in decreased activity of TRPV4 protein] which results in decreased susceptibility to Buthionine Sulfoximine CTD PMID:20064552 ruthenium red decreases activity EXP 6480464 Ruthenium Red results in decreased activity of TRPV4 protein CTD PMID:20064552 S-butyl-DL-homocysteine (S,R)-sulfoximine multiple interactions EXP 6480464 [Gadolinium results in decreased activity of TRPV4 protein] which results in decreased susceptibility to Buthionine Sulfoximine, [Ruthenium Red results in decreased activity of TRPV4 protein] which results in decreased susceptibility to Buthionine Sulfoximine CTD PMID:20064552 serotonin multiple interactions ISO RGD:735797 6480464 TRPV4 protein promotes the reaction [ITGA2 protein promotes the reaction [[Dinoprostone co-treated with Serotonin] results in increased import of Calcium]] CTD PMID:18234883 silicon dioxide decreases expression ISO RGD:1604803 6480464 Silicon Dioxide analog results in decreased expression of TRPV4 mRNA CTD PMID:25895662 sodium arsenite decreases expression ISO RGD:1604803 6480464 sodium arsenite results in decreased expression of TRPV4 mRNA CTD PMID:24570342 sodium arsenite increases methylation ISO RGD:1604803 6480464 sodium arsenite results in increased methylation of TRPV4 gene CTD PMID:24570342 sodium atom affects abundance ISO RGD:1604803 6480464 TRPV4 gene polymorphism affects the abundance of Sodium CTD PMID:19666518 streptozocin increases response to substance EXP 6480464 TRPV4 protein results in increased susceptibility to Streptozocin CTD PMID:18234883 tetraphene multiple interactions ISO RGD:735797 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of TRPV4 mRNA CTD PMID:27858113 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of TRPV4 mRNA CTD PMID:34492290 titanium dioxide multiple interactions ISO RGD:735797 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TRPV4 mRNA CTD PMID:29950665 toluene 2,4-diisocyanate increases expression ISO RGD:735797 6480464 Toluene 2, 4-Diisocyanate results in increased expression of TRPV4 protein CTD PMID:30517707 toluene 2,4-diisocyanate multiple interactions ISO RGD:735797 6480464 GSK2193874 inhibits the reaction [Toluene 2, 4-Diisocyanate results in increased expression of TRPV4 protein] CTD PMID:30517707 triptonide increases expression ISO RGD:735797 6480464 triptonide results in increased expression of TRPV4 mRNA CTD PMID:33045310 troglitazone increases expression ISO RGD:735797 6480464 troglitazone results in increased expression of TRPV4 mRNA CTD PMID:28973697 vincristine increases response to substance EXP 6480464 TRPV4 protein results in increased susceptibility to Vincristine CTD PMID:18234883 zalcitabine increases response to substance EXP 6480464 TRPV4 protein results in increased susceptibility to Zalcitabine CTD PMID:18234883