Sart3 (spliceosome associated factor 3, U4/U6 recycling protein) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Sart3 (spliceosome associated factor 3, U4/U6 recycling protein) Rattus norvegicus
Analyze
Symbol: Sart3
Name: spliceosome associated factor 3, U4/U6 recycling protein
RGD ID: 1311646
Description: Predicted to enable histone binding activity; snRNA binding activity; and ubiquitin-specific protease binding activity. Predicted to be involved in nucleosome assembly; spliceosomal tri-snRNP complex assembly; and transcription elongation-coupled chromatin remodeling. Predicted to act upstream of or within several processes, including cell morphogenesis; hematopoietic stem cell proliferation; and homeostasis of number of cells. Predicted to be located in Cajal body. Predicted to be part of ASAP complex; U4/U6 snRNP; and U6atac snRNP. Predicted to be active in cytoplasm and nucleoplasm. Orthologous to human SART3 (spliceosome associated factor 3, U4/U6 recycling protein); PARTICIPATES IN spliceosome pathway; INTERACTS WITH 2,4-dinitrotoluene; bisphenol A; C60 fullerene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC304582; squamous cell carcinoma antigen recognized by T-cells 3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81248,519,579 - 48,547,584 (+)NCBIGRCr8
mRatBN7.21242,859,026 - 42,887,041 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1242,859,305 - 42,887,038 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1244,025,248 - 44,052,972 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01244,638,843 - 44,666,568 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01243,699,375 - 43,727,099 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01248,628,198 - 48,656,096 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1248,628,278 - 48,656,096 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01250,410,018 - 50,438,126 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41243,893,486 - 43,921,131 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11243,756,871 - 43,783,811 (+)NCBI
Celera1244,460,912 - 44,488,637 (+)NCBICelera
Cytogenetic Map12q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Sart3RatPorokeratosis 3, Multiple Types  ISOSART3 (Homo sapiens)8554872ClinVar Annotator: match by term: POROKERATOSIS 3 and MULTIPLE TYPESClinVarPMID:15840095 and PMID:17392836

1 to 20 of 70 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Sart3Rat(1->4)-beta-D-glucan multiple interactionsISOSart3 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of SART3 mRNACTDPMID:36331819
Sart3Rat1,2-dimethylhydrazine multiple interactionsISOSart3 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of SART3 mRNACTDPMID:22206623
Sart3Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOSart3 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of SART3 mRNACTDPMID:21570461
Sart3Rat2,4,6-tribromophenol decreases expressionISOSART3 (Homo sapiens)64804642 more ...CTDPMID:31675489
Sart3Rat2,4-dinitrotoluene affects expressionEXP 64804642 and 4-dinitrotoluene affects the expression of SART3 mRNACTDPMID:21346803
Sart3Rat3,3',5,5'-tetrabromobisphenol A decreases expressionISOSART3 (Homo sapiens)6480464tetrabromobisphenol A results in decreased expression of SART3 proteinCTDPMID:31675489
Sart3Rataflatoxin B1 decreases methylationISOSART3 (Homo sapiens)6480464Aflatoxin B1 results in decreased methylation of SART3 geneCTDPMID:27153756
Sart3RatAflatoxin B2 alpha decreases methylationISOSART3 (Homo sapiens)6480464aflatoxin B2 results in decreased methylation of SART3 intronCTDPMID:30157460
Sart3Ratall-trans-retinoic acid decreases expressionISOSART3 (Homo sapiens)6480464Tretinoin results in decreased expression of SART3 mRNACTDPMID:21934132
Sart3Rataristolochic acid A increases expressionISOSART3 (Homo sapiens)6480464aristolochic acid I results in increased expression of SART3 mRNACTDPMID:33212167
Sart3Ratarsane affects methylationISOSART3 (Homo sapiens)6480464Arsenic affects the methylation of SART3 geneCTDPMID:25304211
Sart3Ratarsane multiple interactionsISOSART3 (Homo sapiens)6480464[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of SART3 mRNACTDPMID:39836092
Sart3Ratarsenic atom affects methylationISOSART3 (Homo sapiens)6480464Arsenic affects the methylation of SART3 geneCTDPMID:25304211
Sart3Ratarsenic atom multiple interactionsISOSART3 (Homo sapiens)6480464[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of SART3 mRNACTDPMID:39836092
Sart3Ratarsenite(3-) multiple interactionsISOSART3 (Homo sapiens)6480464arsenite inhibits the reaction [G3BP1 protein binds to SART3 mRNA] and arsenite promotes the reaction [G3BP1 protein binds to SART3 protein]CTDPMID:32406909
Sart3Ratbenzo[a]pyrene increases expressionISOSart3 (Mus musculus)6480464Benzo(a)pyrene results in increased expression of SART3 mRNACTDPMID:22228805
Sart3Ratbenzo[a]pyrene decreases methylationISOSART3 (Homo sapiens)6480464Benzo(a)pyrene results in decreased methylation of SART3 promoterCTDPMID:27901495
Sart3Ratbenzo[a]pyrene diol epoxide I decreases expressionISOSART3 (Homo sapiens)64804647 more ...CTDPMID:19150397 and PMID:20018196
Sart3Ratbeta-lapachone increases expressionISOSART3 (Homo sapiens)6480464beta-lapachone results in increased expression of SART3 mRNACTDPMID:38218311
Sart3Ratbisphenol A affects expressionEXP 6480464bisphenol A affects the expression of SART3 mRNACTDPMID:25181051

1 to 20 of 70 rows

Biological Process
1 to 20 of 26 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Sart3Ratbiological_process  ND 159840707/2015: no relevant rat dataRGD 
Sart3Ratcell morphogenesis acts_upstream_of_or_withinISOSart3 (Mus musculus)1624291MGI:5052106 PMID:21447833RGDPMID:21447833
Sart3Ratcell morphogenesis acts_upstream_of_or_withinIEAUniProtKB:Q9JLI8 and ensembl:ENSMUSP000000191181600115GO_REF:0000107EnsemblGO_REF:0000107
Sart3Rathematopoietic stem cell proliferation acts_upstream_of_or_withinISOSart3 (Mus musculus)1624291MGI:5052106 PMID:21447833RGDPMID:21447833
Sart3Rathematopoietic stem cell proliferation acts_upstream_of_or_withinIEAUniProtKB:Q9JLI8 and ensembl:ENSMUSP000000191181600115GO_REF:0000107EnsemblGO_REF:0000107
Sart3Rathomeostasis of number of cells acts_upstream_of_or_withinIEAUniProtKB:Q9JLI8 and ensembl:ENSMUSP000000191181600115GO_REF:0000107EnsemblGO_REF:0000107
Sart3Rathomeostasis of number of cells acts_upstream_of_or_withinISOSart3 (Mus musculus)1624291MGI:5052106 PMID:21447833RGDPMID:21447833
Sart3RatmRNA processing involved_inIEAUniProtKB-KW:KW-05071600115GO_REF:0000043UniProtGO_REF:0000043
Sart3RatmRNA splicing, via spliceosome involved_inISOSART3 (Homo sapiens)1624291 PMID:15314151RGDPMID:15314151
Sart3RatmRNA splicing, via spliceosome involved_inIEAUniProtKB:Q15020 and ensembl:ENSP000004493861600115GO_REF:0000107EnsemblGO_REF:0000107
Sart3RatmRNA splicing, via spliceosome involved_inIBAPANTHER:PTN000397856 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Sart3Ratnucleosome assembly involved_inISOSART3 (Homo sapiens)1624291 PMID:24526689RGDPMID:24526689
Sart3Ratnucleosome assembly involved_inIEAUniProtKB:Q15020 and ensembl:ENSP000004493861600115GO_REF:0000107EnsemblGO_REF:0000107
Sart3Ratregulation of gene expression acts_upstream_of_or_withinISOSART3 (Homo sapiens)1624291 PMID:21447833RGDPMID:21447833
Sart3Ratregulation of gene expression acts_upstream_of_or_withinIEAUniProtKB:Q15020 and ensembl:ENSP000004493861600115GO_REF:0000107EnsemblGO_REF:0000107
Sart3Ratregulation of RNA metabolic process involved_inIEAUniProtKB:Q15020 and ensembl:ENSP000004493861600115GO_REF:0000107EnsemblGO_REF:0000107
Sart3Ratregulation of RNA metabolic process involved_inISOSART3 (Homo sapiens)1624291 PMID:32839293RGDPMID:32839293
Sart3RatRNA processing involved_inIEAInterPro:IPR003107 and InterPro:IPR0088471600115GO_REF:0000002InterProGO_REF:0000002
Sart3RatRNA splicing involved_inIEAUniProtKB-KW:KW-05081600115GO_REF:0000043UniProtGO_REF:0000043
Sart3Ratspliceosomal snRNP assembly involved_inISOSART3 (Homo sapiens)1624291 PMID:14749385 and PMID:15314151RGDPMID:14749385 and PMID:15314151
1 to 20 of 26 rows

Cellular Component
1 to 20 of 24 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Sart3RatASAP complex part_ofIBAPANTHER:PTN000397856 and UniProtKB:Q152871600115GO_REF:0000033GO_CentralGO_REF:0000033
Sart3RatCajal body located_inISOSART3 (Homo sapiens)1624291 PMID:12578909RGDPMID:12578909
Sart3RatCajal body located_inIEAUniProtKB:Q15020 and ensembl:ENSP000004493861600115GO_REF:0000107EnsemblGO_REF:0000107
Sart3RatCajal body located_inIEAUniProtKB:Q9JLI8 and ensembl:ENSMUSP000000191181600115GO_REF:0000107EnsemblGO_REF:0000107
Sart3RatCajal body located_inISOSart3 (Mus musculus)1624291 PMID:12578909RGDPMID:12578909
Sart3Ratcytoplasm is_active_inIBAPANTHER:PTN000397856 and UniProtKB:Q152871600115GO_REF:0000033GO_CentralGO_REF:0000033
Sart3Ratnucleoplasm located_inISOSART3 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Sart3Ratnucleoplasm located_inIEAUniProtKB:Q9JLI8 and ensembl:ENSMUSP000000191181600115GO_REF:0000107EnsemblGO_REF:0000107
Sart3Ratnucleoplasm located_inISOSart3 (Mus musculus)1624291 PMID:12578909RGDPMID:12578909
Sart3Ratnucleoplasm is_active_inIBAMGI:1858230 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Sart3Ratnucleoplasm located_inISOSART3 (Homo sapiens)1624291 PMID:12578909RGDPMID:12578909
Sart3Ratnucleoplasm located_inIEAUniProtKB:Q15020 and ensembl:ENSP000004493861600115GO_REF:0000107EnsemblGO_REF:0000107
Sart3Ratnucleus located_inISOSART3 (Homo sapiens)1624291 PMID:24526689RGDPMID:24526689
Sart3Ratnucleus located_inIEAInterPro:IPR0088471600115GO_REF:0000002InterProGO_REF:0000002
Sart3Ratnucleus located_inIEAUniProtKB:Q15020 and ensembl:ENSP000004493861600115GO_REF:0000107EnsemblGO_REF:0000107
Sart3Ratnucleus located_inIEAUniProtKB-SubCell:SL-01911600115GO_REF:0000044UniProtGO_REF:0000044
Sart3Ratnucleus located_inIEAUniProtKB-KW:KW-05391600115GO_REF:0000043UniProtGO_REF:0000043
Sart3Ratnucleus is_active_inISOSART3 (Homo sapiens)1624291 PMID:32839293RGDPMID:32839293
Sart3RatU4/U6 snRNP located_inISOSART3 (Homo sapiens)1624291 PMID:12032085RGDPMID:12032085
Sart3RatU4/U6 snRNP located_inIEAUniProtKB:Q15020 and ensembl:ENSP000004493861600115GO_REF:0000107EnsemblGO_REF:0000107
1 to 20 of 24 rows

Molecular Function
1 to 18 of 18 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Sart3Rathistone binding enablesISOSART3 (Homo sapiens)1624291 PMID:24526689RGDPMID:24526689
Sart3Rathistone binding enablesIEAUniProtKB:Q15020 and ensembl:ENSP000004493861600115GO_REF:0000107EnsemblGO_REF:0000107
Sart3Ratnucleic acid binding enablesIEAInterPro:IPR0359791600115GO_REF:0000002InterProGO_REF:0000002
Sart3Ratprotein binding enablesISOSART3 (Homo sapiens)1624291UniProtKB:F5HFL9 more ...RGDPMID:11477570 more ...
Sart3Ratprotein-macromolecule adaptor activity enablesISOSART3 (Homo sapiens)1624291 PMID:32839293RGDPMID:32839293
Sart3Ratprotein-macromolecule adaptor activity enablesIEAUniProtKB:Q15020 and ensembl:ENSP000004493861600115GO_REF:0000107EnsemblGO_REF:0000107
Sart3RatRNA binding enablesIEAUniProtKB-KW:KW-06941600115GO_REF:0000043UniProtGO_REF:0000043
Sart3RatRNA binding enablesIEAUniRule:UR0004146191600115GO_REF:0000104UniProtGO_REF:0000104
Sart3RatRNA binding enablesIEAInterPro:IPR0005041600115GO_REF:0000002InterProGO_REF:0000002
Sart3RatU4 snRNA binding enablesISOSART3 (Homo sapiens)1624291 PMID:12032085 and PMID:14749385RGDPMID:12032085 and PMID:14749385
Sart3RatU4 snRNA binding NOT|enablesISOSART3 (Homo sapiens)1624291 PMID:15314151RGDPMID:15314151
Sart3RatU6 snRNA binding enablesISOSART3 (Homo sapiens)1624291 PMID:12032085 more ...RGDPMID:12032085 more ...
Sart3RatU6 snRNA binding enablesIEAUniProtKB:Q15020 and ensembl:ENSP000004493861600115GO_REF:0000107EnsemblGO_REF:0000107
Sart3RatU6 snRNA binding NOT|enablesISOSART3 (Homo sapiens) and UniProtKB:Q15020-21624291 PMID:15314151RGDPMID:15314151
Sart3RatU6atac snRNA binding enablesISOSART3 (Homo sapiens)1624291 PMID:14749385RGDPMID:14749385
Sart3RatU6atac snRNA binding enablesIEAUniProtKB:Q15020 and ensembl:ENSP000004493861600115GO_REF:0000107EnsemblGO_REF:0000107
Sart3Ratubiquitin-specific protease binding enablesISOSART3 (Homo sapiens)1624291UniProtKB:Q13107 more ...RGDPMID:20595234 and PMID:24526689
Sart3Ratubiquitin-specific protease binding enablesIEAUniProtKB:Q15020 and ensembl:ENSP000004493861600115GO_REF:0000107EnsemblGO_REF:0000107
1 to 18 of 18 rows

RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Sart3Ratspliceosome pathway   ISOSART3 (Homo sapiens)9686090 RGD 

#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
7. Structural analyses of the pre-mRNA splicing machinery. Zhang L, etal., Protein Sci. 2013 Jun;22(6):677-92. doi: 10.1002/pro.2266. Epub 2013 May 8.
PMID:12032085   PMID:12578909   PMID:14749385   PMID:15314151   PMID:20595234   PMID:21447833   PMID:22658674   PMID:22681889   PMID:24526689   PMID:31505169  



Sart3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81248,519,579 - 48,547,584 (+)NCBIGRCr8
mRatBN7.21242,859,026 - 42,887,041 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1242,859,305 - 42,887,038 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1244,025,248 - 44,052,972 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01244,638,843 - 44,666,568 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01243,699,375 - 43,727,099 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01248,628,198 - 48,656,096 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1248,628,278 - 48,656,096 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01250,410,018 - 50,438,126 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41243,893,486 - 43,921,131 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11243,756,871 - 43,783,811 (+)NCBI
Celera1244,460,912 - 44,488,637 (+)NCBICelera
Cytogenetic Map12q16NCBI
SART3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812108,522,214 - 108,561,173 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12108,522,214 - 108,561,400 (-)EnsemblGRCh38hg38GRCh38
GRCh3712108,915,991 - 108,954,949 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612107,440,121 - 107,479,295 (-)NCBINCBI36Build 36hg18NCBI36
Build 3412107,418,823 - 107,457,404NCBI
Celera12108,585,375 - 108,624,556 (-)NCBICelera
Cytogenetic Map12q23.3NCBI
HuRef12105,980,549 - 106,019,720 (-)NCBIHuRef
CHM1_112108,882,205 - 108,921,384 (-)NCBICHM1_1
T2T-CHM13v2.012108,491,579 - 108,530,540 (-)NCBIT2T-CHM13v2.0
Sart3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395113,880,505 - 113,910,461 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5113,880,507 - 113,910,571 (-)EnsemblGRCm39 Ensembl
GRCm385113,742,444 - 113,772,400 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5113,742,446 - 113,772,510 (-)EnsemblGRCm38mm10GRCm38
MGSCv375114,192,455 - 114,221,658 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365114,003,445 - 114,032,648 (-)NCBIMGSCv36mm8
Celera5110,843,569 - 110,872,772 (-)NCBICelera
Cytogenetic Map5FNCBI
cM Map555.55NCBI
Sart3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554559,802,260 - 9,832,957 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554559,802,260 - 9,833,326 (-)NCBIChiLan1.0ChiLan1.0
SART3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210116,582,348 - 116,621,301 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112116,578,763 - 116,617,683 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012106,093,738 - 106,132,710 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112109,490,261 - 109,529,091 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12109,489,932 - 109,529,091 (-)Ensemblpanpan1.1panPan2
SART3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12618,308,065 - 18,345,903 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2618,308,733 - 18,345,353 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2617,453,933 - 17,491,866 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02618,654,344 - 18,692,293 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2618,655,068 - 18,692,279 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12617,662,926 - 17,700,867 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02618,645,348 - 18,680,132 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02618,663,732 - 18,701,674 (+)NCBIUU_Cfam_GSD_1.0
Sart3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118144,984,772 - 145,024,975 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936769450,917 - 491,210 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936769450,919 - 490,938 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SART3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1442,223,964 - 42,261,811 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11442,223,752 - 42,259,992 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21444,768,763 - 44,805,281 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SART3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111103,716,517 - 103,752,087 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11103,715,292 - 103,751,874 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037141,343,233 - 141,378,581 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sart3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474711,775,039 - 11,807,552 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474711,775,012 - 11,807,597 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Sart3
170 total Variants


Assembly: Rnor_5.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain Variant Page
12 50418076 50418077 G T snv IS/Kyo (KyushuU), DOB/Oda (KyushuU), IS-Tlk/Kyo (KyushuU) View more Information

Predicted Target Of
Summary Value
Count of predictions:264
Count of miRNA genes:173
Interacting mature miRNAs:202
Transcripts:ENSRNOT00000000891
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 31 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
631560Apr1Acute phase response QTL 16.1orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)121914436246669029Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
8693635Alc28Alcohol consumption QTL 282.70.439drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)122308134044726024Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
7411643Foco20Food consumption QTL 200.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)122032881946669029Rat
61324Eae5Experimental allergic encephalomyelitis QTL 514nervous system integrity trait (VT:0010566)percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time (CMO:0001402)121961087046669029Rat
1549912Bp268Blood pressure QTL 268arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)101318273646669029Rat
2302060Pia37Pristane induced arthritis QTL 376.10.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)121319815746669029Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121281238546669029Rat
1300162Bp188Blood pressure QTL 1883.19arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)123210317445899022Rat

1 to 10 of 31 rows
RH132969  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21242,886,745 - 42,886,961 (+)MAPPERmRatBN7.2
Rnor_6.01248,655,801 - 48,656,016NCBIRnor6.0
Rnor_5.01250,437,831 - 50,438,046UniSTSRnor5.0
RGSC_v3.41243,920,837 - 43,921,052UniSTSRGSC3.4
Celera1244,488,343 - 44,488,558UniSTS
Cytogenetic Map12q16UniSTS
SART3  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21242,883,743 - 42,884,280 (+)MAPPERmRatBN7.2
Rnor_6.01248,652,799 - 48,653,335NCBIRnor6.0
Rnor_5.01250,434,831 - 50,435,367UniSTSRnor5.0
RGSC_v3.41243,917,835 - 43,918,371UniSTSRGSC3.4
Celera1244,485,341 - 44,485,877UniSTS
Cytogenetic Map12q16UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000000891   ⟹   ENSRNOP00000000891
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1242,859,305 - 42,887,038 (+)Ensembl
Rnor_6.0 Ensembl1248,628,278 - 48,656,096 (+)Ensembl
RefSeq Acc Id: NM_001107156   ⟹   NP_001100626
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81248,519,853 - 48,547,583 (+)NCBI
mRatBN7.21242,859,308 - 42,887,040 (+)NCBI
Rnor_6.01248,628,454 - 48,656,095 (+)NCBI
Rnor_5.01250,410,018 - 50,438,126 (+)NCBI
RGSC_v3.41243,893,486 - 43,921,131 (+)RGD
Celera1244,460,912 - 44,488,637 (+)RGD
Sequence:
RefSeq Acc Id: XM_006249501   ⟹   XP_006249563
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81248,519,579 - 48,547,584 (+)NCBI
mRatBN7.21242,859,036 - 42,887,041 (+)NCBI
Rnor_6.01248,628,198 - 48,656,096 (+)NCBI
Rnor_5.01250,410,018 - 50,438,126 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006249502   ⟹   XP_006249564
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81248,520,037 - 48,547,584 (+)NCBI
mRatBN7.21242,859,492 - 42,887,041 (+)NCBI
Rnor_6.01248,628,693 - 48,656,096 (+)NCBI
Rnor_5.01250,410,018 - 50,438,126 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039089525   ⟹   XP_038945453
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81248,534,705 - 48,547,584 (+)NCBI
mRatBN7.21242,874,161 - 42,887,041 (+)NCBI
Protein RefSeqs NP_001100626 (Get FASTA)   NCBI Sequence Viewer  
  XP_006249563 (Get FASTA)   NCBI Sequence Viewer  
  XP_006249564 (Get FASTA)   NCBI Sequence Viewer  
  XP_038945453 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM13966 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000000891
  ENSRNOP00000000891.4
  ENSRNOP00000104077
RefSeq Acc Id: NP_001100626   ⟸   NM_001107156
- UniProtKB: A6J227 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006249563   ⟸   XM_006249501
- Peptide Label: isoform X1
- UniProtKB: D3ZAS8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006249564   ⟸   XM_006249502
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSRNOP00000000891   ⟸   ENSRNOT00000000891
RefSeq Acc Id: XP_038945453   ⟸   XM_039089525
- Peptide Label: isoform X3
RRM

Name Modeler Protein Id AA Range Protein Structure
AF-D3ZAS8-F1-model_v2 AlphaFold D3ZAS8 1-960 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13698721
Promoter ID:EPDNEW_R9245
Type:multiple initiation site
Name:Sart3_1
Description:squamous cell carcinoma antigen recognized by T-cells 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01248,628,450 - 48,628,510EPDNEW


1 to 33 of 33 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-18924 BioCyc
Ensembl Genes ENSRNOG00000000702 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000000891 ENTREZGENE
  ENSRNOT00000000891.6 UniProtKB/TrEMBL
  ENSRNOT00000148999 ENTREZGENE
Gene3D-CATH 1.25.40.10 UniProtKB/TrEMBL
  3.30.70.330 UniProtKB/TrEMBL
InterPro HAT UniProtKB/TrEMBL
  Lsm_interact UniProtKB/TrEMBL
  Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
  RRM_RNP1 UniProtKB/TrEMBL
  SART3_RRM1 UniProtKB/TrEMBL
  SART3_RRM2 UniProtKB/TrEMBL
  Suf UniProtKB/TrEMBL
  TPR-like_helical_dom UniProtKB/TrEMBL
KEGG Report rno:304582 UniProtKB/TrEMBL
NCBI Gene 304582 ENTREZGENE
PANTHER PRE-MRNA PROCESSING PROTEIN PRP39-RELATED UniProtKB/TrEMBL
  RRM DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
Pfam LSM_int_assoc UniProtKB/TrEMBL
  Lsm_interact UniProtKB/TrEMBL
  RRM_1 UniProtKB/TrEMBL
  Suf UniProtKB/TrEMBL
PhenoGen Sart3 PhenoGen
PROSITE RRM UniProtKB/TrEMBL
RatGTEx ENSRNOG00000000702 RatGTEx
SMART HAT UniProtKB/TrEMBL
  RRM UniProtKB/TrEMBL
Superfamily-SCOP SSF48452 UniProtKB/TrEMBL
  SSF54928 UniProtKB/TrEMBL
UniProt A6J227 ENTREZGENE, UniProtKB/TrEMBL
  D3ZAS8 ENTREZGENE, UniProtKB/TrEMBL
1 to 33 of 33 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-08-21 Sart3  spliceosome associated factor 3, U4/U6 recycling protein  Sart3  squamous cell carcinoma antigen recognized by T-cells 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Sart3  squamous cell carcinoma antigen recognized by T-cells 3   Sart3_predicted  squamous cell carcinoma antigen recognized by T-cells 3 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Sart3_predicted  squamous cell carcinoma antigen recognized by T-cells 3 (predicted)      Symbol and Name status set to approved 70820 APPROVED