Tmem119 (transmembrane protein 119)

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Gene: Tmem119 (transmembrane protein 119) Rattus norvegicus

Analyze

Symbol:

Tmem119

Name:

transmembrane protein 119

RGD ID:

1307573

Description:

Predicted to be involved in several processes, including endochondral ossification; negative regulation of bone resorption; and positive regulation of macromolecule metabolic process. Predicted to act upstream of or within osteoblast differentiation. Predicted to be located in endoplasmic reticulum and plasma membrane. Orthologous to human TMEM119 (transmembrane protein 119); INTERACTS WITH all-trans-retinoic acid; bis(2-ethylhexyl) phthalate; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC304581; RGD1307573; similar to hypothetical protein MGC38046; transmembrane protein 119 homolog

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TMEM119 (transmembrane protein 119)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Tmem119 (transmembrane protein 119)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Tmem119 (transmembrane protein 119)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TMEM119 (transmembrane protein 119)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TMEM119 (transmembrane protein 119)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Tmem119 (transmembrane protein 119)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TMEM119 (transmembrane protein 119)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TMEM119 (transmembrane protein 119)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tmem119 (transmembrane protein 119)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Tmem119 (transmembrane protein 119)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	TMEM119 (transmembrane protein 119)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	tmem119b (transmembrane protein 119b)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	12	42,828,621 - 42,835,678 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	42,828,418 - 42,835,689 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	12	43,994,907 - 44,001,984 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	44,608,504 - 44,615,581 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	43,669,038 - 43,676,115 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	48,598,498 - 48,605,704 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	48,598,647 - 48,605,704 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	12	50,380,454 - 50,387,588 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	12	43,863,011 - 43,870,068 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	12	43,731,406 - 43,732,498 (+)	NCBI
Celera	12	44,430,205 - 44,437,274 (+)	NCBI		Celera
Cytogenetic Map	12	q16	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2-methylcholine (ISO)

3-methylcholanthrene (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (EXP,ISO)

arsenite(3-) (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

benzo[e]pyrene (ISO)

bis(2-ethylhexyl) phthalate (EXP)

bisphenol A (EXP,ISO)

Bisphenol B (ISO)

bisphenol F (ISO)

butanal (ISO)

carbon nanotube (ISO)

chloroprene (ISO)

chlorpyrifos (ISO)

choline (ISO)

chromium(6+) (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

diarsenic trioxide (ISO)

dibutyl phthalate (EXP)

diethylstilbestrol (EXP)

dioxygen (ISO)

doxorubicin (ISO)

epoxiconazole (ISO)

ethanol (ISO)

folic acid (ISO)

furan (EXP)

gentamycin (EXP)

L-methionine (ISO)

lidocaine (EXP)

methapyrilene (ISO)

oxaliplatin (EXP)

ozone (ISO)

paracetamol (EXP,ISO)

Soman (EXP)

temozolomide (ISO)

testosterone (ISO)

tetrachloromethane (ISO)

topotecan (EXP)

triclosan (ISO)

tunicamycin (ISO)

valproic acid (ISO)

zaragozic acid A (EXP,ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

endochondral ossification (ISO)

negative regulation of bone resorption (ISO)

negative regulation of myotube differentiation (ISO)

osteoblast differentiation (ISO)

positive regulation of bone development (ISO)

positive regulation of bone mineralization (IBA,ISO)

positive regulation of gene expression (ISO)

positive regulation of osteoblast differentiation (IBA,ISO)

positive regulation of osteoblast proliferation (IBA,ISO)

positive regulation of protein phosphorylation (ISO)

spermatid differentiation (ISO)

spermatogenesis (ISO)

Cellular Component

endoplasmic reticulum (ISO)

plasma membrane (IBA,ISO)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
3.	Comprehensive gene review and curation	RGD comprehensive gene curation

Additional References at PubMed

PMID:12477932	PMID:20025746	PMID:21239498	PMID:22416756	PMID:22579779	PMID:25931508	PMID:26207632

Genomics

Comparative Map Data

Tmem119
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	12	42,828,621 - 42,835,678 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	42,828,418 - 42,835,689 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	12	43,994,907 - 44,001,984 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	44,608,504 - 44,615,581 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	43,669,038 - 43,676,115 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	48,598,498 - 48,605,704 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	48,598,647 - 48,605,704 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	12	50,380,454 - 50,387,588 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	12	43,863,011 - 43,870,068 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	12	43,731,406 - 43,732,498 (+)	NCBI
Celera	12	44,430,205 - 44,437,274 (+)	NCBI		Celera
Cytogenetic Map	12	q16	NCBI

TMEM119
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	108,589,851 - 108,598,084 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	108,589,851 - 108,598,320 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	12	108,983,627 - 108,991,860 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	107,507,756 - 107,515,913 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	12	108,653,016 - 108,661,288 (-)	NCBI		Celera
Cytogenetic Map	12	q23.3	NCBI
HuRef	12	106,047,977 - 106,056,250 (-)	NCBI		HuRef
CHM1_1	12	108,950,373 - 108,958,645 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	12	108,564,436 - 108,572,683 (-)	NCBI		T2T-CHM13v2.0

Tmem119
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	113,931,790 - 113,938,530 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	113,931,790 - 113,938,577 (-)	Ensembl		GRCm39 Ensembl
GRCm38	5	113,793,729 - 113,800,396 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	113,793,729 - 113,800,516 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	114,243,738 - 114,250,367 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	5	114,054,728 - 114,061,357 (-)	NCBI		MGSCv36	mm8
Celera	5	110,894,838 - 110,901,705 (-)	NCBI		Celera
Cytogenetic Map	5	F	NCBI
cM Map	5	55.55	NCBI

Tmem119
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955455	9,856,443 - 9,863,100 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955455	9,856,443 - 9,863,100 (-)	NCBI	ChiLan1.0	ChiLan1.0

TMEM119
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	12	116,651,254 - 116,659,541 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	106,166,737 - 106,173,965 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	109,561,987 - 109,570,389 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	109,563,684 - 109,564,535 (-)	Ensembl	panpan1.1		panPan2

TMEM119
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	26	18,275,719 - 18,282,905 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	26	18,260,923 - 18,282,409 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	26	17,519,003 - 17,526,176 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	26	18,619,952 - 18,627,106 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	26	18,605,512 - 18,626,613 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	26	17,728,101 - 17,735,247 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	26	18,610,928 - 18,618,116 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	26	18,629,671 - 18,636,823 (+)	NCBI		UU_Cfam_GSD_1.0

Tmem119
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	144,959,979 - 144,962,199 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936769	513,695 - 515,769 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TMEM119
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	14	42,190,958 - 42,197,384 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	44,736,255 - 44,742,678 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TMEM119
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	103,787,911 - 103,796,217 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	103,788,407 - 103,789,249 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	141,300,326 - 141,308,958 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tmem119
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624747	11,828,292 - 11,834,855 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Tmem119
41 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	219
Count of miRNA genes:	144
Interacting mature miRNAs:	164
Transcripts:	ENSRNOT00000000889
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
737979	Pia22	Pristane induced arthritis QTL 22	53.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	1	44465750	Rat
634351	Apr5	Acute phase response QTL 5	6.7		blood interleukin-6 amount (VT:0008595)	plasma interleukin-6 level (CMO:0001927)	12	1	44503507	Rat
2302042	Pia38	Pristane induced arthritis QTL 38	3.5	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	12	1	44503507	Rat
634350	Apr4	Acute phase response QTL 4	6		orosomucoid 1 amount (VT:0010541)	plasma orosomucoid 1 level (CMO:0001467)	12	1172005	46172005	Rat
8552918	Pigfal7	Plasma insulin-like growth factor 1 level QTL 7			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	5564495	46669029	Rat
7411547	Bw129	Body weight QTL 129		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	6	5564495	46669029	Rat
7411597	Foco10	Food consumption QTL 10		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	5564495	46669029	Rat
7411641	Foco19	Food consumption QTL 19	27.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	5564495	46669029	Rat
8552964	Pigfal17	Plasma insulin-like growth factor 1 level QTL 17	3.5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	5564495	46669029	Rat
7411588	Foco6	Food consumption QTL 6		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	5564495	46669029	Rat
8552912	Pigfal6	Plasma insulin-like growth factor 1 level QTL 6	5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	5564498	46669029	Rat
10059594	Kidm46	Kidney mass QTL 46	3.79	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	12	6107579	46669029	Rat
1302792	Scl21	Serum cholesterol level QTL 21	3.8	0.0011	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	12	7196730	46669029	Rat
1549829	Scl48	Serum cholesterol level QTL 48	5		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	12	9603277	46669029	Rat
2293699	Bss49	Bone structure and strength QTL 49	5.61	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	12	10474137	46669029	Rat
2300186	Bmd59	Bone mineral density QTL 59	7.1	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	12	10474137	46669029	Rat
1331761	Bp218	Blood pressure QTL 218	2.973		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	11073825	45055165	Rat
61404	Bw120	Body weight QTL 120	5.1		body mass (VT:0001259)	body mass index (BMI) (CMO:0000105)	12	12351619	46669029	Rat
1641928	Alcrsp5	Alcohol response QTL 5			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	12	12812385	46669029	Rat
2303569	Gluco44	Glucose level QTL 44	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	12812385	46669029	Rat
1549902	Bp269	Blood pressure QTL 269			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	13182736	46669029	Rat
1549912	Bp268	Blood pressure QTL 268			arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	10	13182736	46669029	Rat
2302060	Pia37	Pristane induced arthritis QTL 37	6.1	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	12	13198157	46669029	Rat
631560	Apr1	Acute phase response QTL 1	6.1		orosomucoid 1 amount (VT:0010541)	plasma orosomucoid 1 level (CMO:0001467)	12	19144362	46669029	Rat
5684888	Pia42	Pristane induced arthritis QTL 42			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	19610870	42828880	Rat
61324	Eae5	Experimental allergic encephalomyelitis QTL 5	14		nervous system integrity trait (VT:0010566)	percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time (CMO:0001402)	12	19610870	46669029	Rat
7411643	Foco20	Food consumption QTL 20		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	20328819	46669029	Rat
1300175	Cm5	Cardiac mass QTL 5	3.78		heart mass (VT:0007028)	heart left ventricle weight to body weight ratio (CMO:0000530)	12	28064433	45899022	Rat
1600386	Calcic2	Intracellular calcium level QTL 2		0.001	platelet physiology trait (VT:0005464)	platelet intracellular calcium level (CMO:0000922)	12	28064433	46669029	Rat
1300162	Bp188	Blood pressure QTL 188	3.19		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	32103174	45899022	Rat

Markers in Region

D12Rat53

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	42,828,758 - 42,828,880 (+)	MAPPER	mRatBN7.2
Rnor_6.0	12	48,598,785 - 48,598,906	NCBI	Rnor6.0
Rnor_5.0	12	50,380,669 - 50,380,790	UniSTS	Rnor5.0
RGSC_v3.4	12	43,863,148 - 43,863,270	RGD	RGSC3.4
RGSC_v3.4	12	43,863,149 - 43,863,270	UniSTS	RGSC3.4
RGSC_v3.1	12	43,726,536 - 43,726,658	RGD
Celera	12	44,430,343 - 44,430,476	UniSTS
RH 2.0 Map	12	480.4	RGD
SHRSP x BN Map	12	51.7899	RGD
Cytogenetic Map	12	q16	UniSTS

RH131188

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	42,835,444 - 42,835,638 (+)	MAPPER	mRatBN7.2
Rnor_6.0	12	48,605,471 - 48,605,664	NCBI	Rnor6.0
Rnor_5.0	12	50,387,355 - 50,387,548	UniSTS	Rnor5.0
RGSC_v3.4	12	43,869,835 - 43,870,028	UniSTS	RGSC3.4
Celera	12	44,437,041 - 44,437,234	UniSTS
Cytogenetic Map	12	q16	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	2	16	14	6	7	6			13	21	30	11
Low	1	27	43	35	12	35	7	10	61	14	11		7
Below cutoff							1	1					1

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001107155	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006249500	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598354	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC166820	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473973	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000229	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000000889 ⟹ ENSRNOP00000000889

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	12	42,828,418 - 42,835,675 (+)	Ensembl
Rnor_6.0 Ensembl	12	48,598,647 - 48,605,704 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000099644 ⟹ ENSRNOP00000090180

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	12	42,829,373 - 42,835,689 (+)	Ensembl

RefSeq Acc Id:

NM_001107155 ⟹ NP_001100625

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	12	42,828,621 - 42,835,678 (+)	NCBI
Rnor_6.0	12	48,598,647 - 48,605,704 (+)	NCBI
Rnor_5.0	12	50,380,454 - 50,387,588 (+)	NCBI
RGSC_v3.4	12	43,863,011 - 43,870,068 (+)	RGD
Celera	12	44,430,205 - 44,437,274 (+)	RGD

Sequence:

show sequence

GCCAGAGCAGCTGGCGGCAGACAGTCGGACCGAGACAGTTGGACCGAGACAGTCGAACGGTCTA
ACAGGGCCTGGCTTGCCTACCTGGCAGCTGCACCCGGTCCTTTTCCCAGAGCTGGTTCTGTGGG
TCAACATGGTCCCCTGCTTCCTCCTGTCTCTGCTGCTACTTGTGAGGCCTGCGCCTGTGGTGGC
CTACTCTGTGTCCCTCCCGGCCTCCTTCCTGGAGGAAGTGGCGGGCAGTGGGGAAGCTGAGGGT
TCTTCAGCCTCTTCCCCAAGCCTGCTGCCGCCCCGGACTCCAGCCTTCAGTCCCACACCAGGGA
GGACCCAGCCCACAGCTCCGGTCGGCCCTGTGCCACCCACCAACCTCCTGGATGGGATCGTGGA
CTTCTTCCGCCAGTATGTGATGCTCATTGCGGTGGTGGGCTCGCTGACCTTTCTCATCATGTTC
ATAGTCTGCGCGGCACTCATCACGCGCCAGAAGCACAAGGCCACAGCCTACTACCCGTCCTCTT
TCCCCGAAAAGAAGTATGTGGACCAGAGAGACCGGGCTGGGGGGCCCCATGCCTTCAGCGAGGT
CCCTGACAGGGCACCTGACAGCCGGCAGGAAGAGGGCCTGGACTCCTCCCAGCAGCTCCAGGCT
GACATTCTGGCTGCTACTCAGAACCTCCGGTCTCCAGCTAGAGCCCTGCCAGGCAGTGGGGAGG
GAACAAAACAGGTGAAGGGTGGGTCGGAGGAGGAGGAGGAGAAGGAAGAGGAGGTGTTCAGTGG
CCAGGAGGAGCCCCGGGAAGCCCCAGTATGTGGGGTCACTGAAGAGAAGCCGGAGGTCCCTGAC
GAGACAGCCTCAGCAGAGGCTGAAGGGGTTCCCGCAGCCAGCGAGGGCCAAGGGGAACCAGAAG
GGTCTTTCTCCTTAGCCCAGGAACCCCAGGGAGCAGCTGGTCCTTCCGAAAGGTCCTGTGCCTG
CAACAGAATCTCCCCTAATGTGTAACAGGCCCCAGAACTGTGAGGCCTGACTCTTGGGTCCTCG
AAGGTCACCTCCTTGGTCAAGAAAGGCATTCAGCTTTGACTGCTTCTTGACACCCTGCCTTGGC
CATTGTGGGTGCCAATCCTGACCCTGAATGGGCAAAGCTGCTGGCCTCTGGTGTACCCCAGGAA
ACACCACCCCAAGTTCCAGCGCCCTTAATGACTCTCACCATCCTGGGGGCTTCACCCCGAAGCA
CCACTTCTCTGGAAGGGGAAGGTCAGACACATCCCAGTTGGAGCCGCAATGAGGCAGTCCTCAG
AACAGAAGGGGAACAGGCCAGAGGCTGTCTGTGACATACACAGTAAACACCCCTGCTTGCACCT
TGGCTGTGGAGACAAGAGGGGCTGTTGATTCAGATGGGCCTGCGGTGTCCTCTCTGCCGTTGTG
CCCTGCAGGATAGCAAGGTGCAGTCCGTGTCTGGTAATGCCAGGGACTGCAGAGTCCTTCGCAT
CTCCTGATCACCGCAGTGTCTCTGTCACGCTGCCCCTGTTCAGTGGACTTGATTAGTTAGGAAG
CTTCTGGAAGGGACCCCTAATTATATCACGGAGTTTCCCCATGGAAACACAAACTCCAAATCAT
GTGACTTTAGGAGCCACCGTGCCCCTCCAAAGACTGACATGGCTACTCTAAGGGTTCCCACTGG
GCTGGCTTTGCTACGCTTTCTTCACGTTGCTTCATTATTACCAGGAGGTCTCATAGCTACAAAG
TCCAATCTCACAGCACCCAGTCTGGAAAACAGTGTTCTCAGGTTTTCTCCAAGGCACCCCACTT
CCTGATTGGTTCAGAGTTGGAATGTGGCACGCAGGGCGTCCGGCTCACTCAAGTGTCAAGTGAC
CCTGACTTGGGTGTGTGCAAGACATCTTGCTGTCAATGCTGGGGTGAGGGAGAAGCCAAGGGGA
TGTTTGGGGGTCACAGCCATTCTGGATTCTGACACCCAGCCTGGAGCAGGGGCCTGGCCCATTC
TACGCTCACACAGTGGTCTAGCAGCCTGAACCCACACCGTTCCTCAACCCTCAACAGTGCTGAG
GCTCTGTCCTGTTGGGGATTTTGGGGTTCACTACACCTGCATTCAGGGCTCCCCGAGATGTCAG
CTCTTCAGGTGTGGATATATGACACACTAGCATAATAAACCTTGATCTGGCTTGA

hide sequence

RefSeq Acc Id:

XM_017598354 ⟹ XP_017453843

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	12	42,828,865 - 42,835,678 (+)	NCBI
Rnor_6.0	12	48,599,271 - 48,605,704 (+)	NCBI

Sequence:

show sequence

GCGTAAAAGTTGGTGTGTAGGCTCTGAGACCTAAGGCTCCTTCCAAGCCTCTTCTTGAGGGGCC
CAGGTCCCTGTCCTTGCAGGCCCCAAGGGAATAGGCTGGGGATACGATGCTTCAGCTGGAGCCC
CTCCCCCCAAGTCTCCTAATTGAAACCGGGTTTCTGTGGCCTGCCTCTCCACCACTGGCCATCA
GTTTCTGAGTGATGGCTTAGCTGTCTCAGGTCCTGGGGTACCAGTCCTTGGGGGTGGATTCACC
TCATCTGCATATTCACCGGCATCTCGATTTAAAACAGAAGCTTCTAAGACAGAGGGTCCGGGAG
GGCATCCTGGGTTCTGTGGGTCAACATGGTCCCCTGCTTCCTCCTGTCTCTGCTGCTACTTGTG
AGGCCTGCGCCTGTGGTGGCCTACTCTGTGTCCCTCCCGGCCTCCTTCCTGGAGGAAGTGGCGG
GCAGTGGGGAAGCTGAGGGTTCTTCAGCCTCTTCCCCAAGCCTGCTGCCGCCCCGGACTCCAGC
CTTCAGTCCCACACCAGGGAGGACCCAGCCCACAGCTCCGGTCGGCCCTGTGCCACCCACCAAC
CTCCTGGATGGGATCGTGGACTTCTTCCGCCAGTATGTGATGCTCATTGCGGTGGTGGGCTCGC
TGACCTTTCTCATCATGTTCATAGTCTGCGCGGCACTCATCACGCGCCAGAAGCACAAGGCCAC
AGCCTACTACCCGTCCTCTTTCCCCGAAAAGAAGTATGTGGACCAGAGAGACCGGGCTGGGGGG
CCCCATGCCTTCAGCGAGGTCCCTGACAGGGCACCTGACAGCCGGCAGGAAGAGGGCCTGGACT
CCTCCCAGCAGCTCCAGGCTGACATTCTGGCTGCTACTCAGAACCTCCGGTCTCCAGCTAGAGC
CCTGCCAGGCAGTGGGGAGGGAACAAAACAGGTGAAGGGTGGGTCGGAGGAGGAGGAGGAGAAG
GAAGAGGAGGTGTTCAGTGGCCAGGAGGAGCCCCGGGAAGCCCCAGTATGTGGGGTCACTGAAG
AGAAGCCGGAGGTCCCTGACGAGACAGCCTCAGCAGAGGCTGAAGGGGTTCCCGCAGCCAGCGA
GGGCCAAGGGGAACCAGAAGGGTCTTTCTCCTTAGCCCAGGAACCCCAGGGAGCAGCTGGTCCT
TCCGAAAGGTCCTGTGCCTGCAACAGAATCTCCCCTAATGTGTAACAGGCCCCAGAACTGTGAG
GCCTGACTCTTGGGTCCTCGAAGGTCACCTCCTTGGTCAAGAAAGGCATTCAGCTTTGACTGCT
TCTTGACACCCTGCCTTGGCCATTGTGGGTGCCAATCCTGACCCTGAATGGGCAAAGCTGCTGG
CCTCTGGTGTACCCCAGGAAACACCACCCCAAGTTCCAGCGCCCTTAATGACTCTCACCATCCT
GGGGGCTTCACCCCGAAGCACCACTTCTCTGGAAGGGGAAGGTCAGACACATCCCAGTTGGAGC
CGCAATGAGGCAGTCCTCAGAACAGAAGGGGAACAGGCCAGAGGCTGTCTGTGACATACACAGT
AAACACCCCTGCTTGCACCTTGGCTGTGGAGACAAGAGGGGCTGTTGATTCAGATGGGCCTGCG
GTGTCCTCTCTGCCGTTGTGCCCTGCAGGATAGCAAGGTGCAGTCCGTGTCTGGTAATGCCAGG
GACTGCAGAGTCCTTCGCATCTCCTGATCACCGCAGTGTCTCTGTCACGCTGCCCCTGTTCAGT
GGACTTGATTAGTTAGGAAGCTTCTGGAAGGGACCCCTAATTATATCACGGAGTTTCCCCATGG
AAACACAAACTCCAAATCATGTGACTTTAGGAGCCACCGTGCCCCTCCAAAGACTGACATGGCT
ACTCTAAGGGTTCCCACTGGGCTGGCTTTGCTACGCTTTCTTCACGTTGCTTCATTATTACCAG
GAGGTCTCATAGCTACAAAGTCCAATCTCACAGCACCCAGTCTGGAAAACAGTGTTCTCAGGTT
TTCTCCAAGGCACCCCACTTCCTGATTGGTTCAGAGTTGGAATGTGGCACGCAGGGCGTCCGGC
TCACTCAAGTGTCAAGTGACCCTGACTTGGGTGTGTGCAAGACATCTTGCTGTCAATGCTGGGG
TGAGGGAGAAGCCAAGGGGATGTTTGGGGGTCACAGCCATTCTGGATTCTGACACCCAGCCTGG
AGCAGGGGCCTGGCCCATTCTACGCTCACACAGTGGTCTAGCAGCCTGAACCCACACCGTTCCT
CAACCCTCAACAGTGCTGAGGCTCTGTCCTGTTGGGGATTTTGGGGTTCACTACACCTGCATTC
AGGGCTCCCCGAGATGTCAGCTCTTCAGGTGTGGATATATGACACACTAGCATAATAAACCTTG
ATCTGGCTTGA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001100625	(Get FASTA)	NCBI Sequence Viewer
	XP_017453843	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI66820	(Get FASTA)	NCBI Sequence Viewer
	EDM13961	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000000889.4
	ENSRNOP00000090180
	ENSRNOP00000090180.1

RefSeq Acc Id:	NP_001100625 ⟸ NM_001107155
- Peptide Label:	precursor
- UniProtKB:	B2RYL3 (UniProtKB/TrEMBL), A6J222 (UniProtKB/TrEMBL), F6T7Z2 (UniProtKB/TrEMBL), A0A8I6AD54 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVPCFLLSLLLLVRPAPVVAYSVSLPASFLEEVAGSGEAEGSSASSPSLLPPRTPAFSPTPGRT QPTAPVGPVPPTNLLDGIVDFFRQYVMLIAVVGSLTFLIMFIVCAALITRQKHKATAYYPSSFP EKKYVDQRDRAGGPHAFSEVPDRAPDSRQEEGLDSSQQLQADILAATQNLRSPARALPGSGEGT KQVKGGSEEEEEKEEEVFSGQEEPREAPVCGVTEEKPEVPDETASAEAEGVPAASEGQGEPEGS FSLAQEPQGAAGPSERSCACNRISPNV hide sequence

RefSeq Acc Id:	XP_017453843 ⟸ XM_017598354
- Peptide Label:	isoform X1
- UniProtKB:	B2RYL3 (UniProtKB/TrEMBL), A6J222 (UniProtKB/TrEMBL), F6T7Z2 (UniProtKB/TrEMBL), A0A8I6AD54 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVPCFLLSLLLLVRPAPVVAYSVSLPASFLEEVAGSGEAEGSSASSPSLLPPRTPAFSPTPGRT QPTAPVGPVPPTNLLDGIVDFFRQYVMLIAVVGSLTFLIMFIVCAALITRQKHKATAYYPSSFP EKKYVDQRDRAGGPHAFSEVPDRAPDSRQEEGLDSSQQLQADILAATQNLRSPARALPGSGEGT KQVKGGSEEEEEKEEEVFSGQEEPREAPVCGVTEEKPEVPDETASAEAEGVPAASEGQGEPEGS FSLAQEPQGAAGPSERSCACNRISPNV hide sequence

RefSeq Acc Id:

ENSRNOP00000000889 ⟸ ENSRNOT00000000889

RefSeq Acc Id:

ENSRNOP00000090180 ⟸ ENSRNOT00000099644

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-B2RYL3-F1-model_v2	AlphaFold	B2RYL3	1-283	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13698719

Promoter ID:

EPDNEW_R9243

Type:

initiation region

Name:

Tmem119_1

Description:

transmembrane protein 119

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	12	48,598,669 - 48,598,729	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1307573	AgrOrtholog
BioCyc Gene	G2FUF-18928	BioCyc
Ensembl Genes	ENSRNOG00000000700	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000000889.5	UniProtKB/TrEMBL
	ENSRNOT00000099644	ENTREZGENE
	ENSRNOT00000099644.1	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:8367783	IMAGE-MGC_LOAD
InterPro	TMEM119	UniProtKB/TrEMBL
KEGG Report	rno:304581	UniProtKB/TrEMBL
MGC_CLONE	MGC:188696	IMAGE-MGC_LOAD
NCBI Gene	304581	ENTREZGENE
PANTHER	PTHR28645	UniProtKB/TrEMBL
	TRANSMEMBRANE PROTEIN 119	UniProtKB/TrEMBL
Pfam	TMEM119	UniProtKB/TrEMBL
PhenoGen	Tmem119	PhenoGen
RatGTEx	ENSRNOG00000000700	RatGTEx
UniProt	A0A8I6AD54	ENTREZGENE, UniProtKB/TrEMBL
	A6J222	ENTREZGENE, UniProtKB/TrEMBL
	B2RYL3	ENTREZGENE
	F6T7Z2	ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary	B2RYL3	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-04	Tmem119	transmembrane protein 119	Tmem119_predicted	transmembrane protein 119 homolog (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-30	Tmem119_predicted	transmembrane protein 119 homolog (predicted)	RGD1307573_predicted	similar to hypothetical protein MGC38046 (predicted)	Symbol and Name updated	1299863	APPROVED
2005-01-20	RGD1307573_predicted	similar to hypothetical protein MGC38046 (predicted)	LOC304581_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC304581_predicted	similar to hypothetical protein MGC38046 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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