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Gene: Fbxw8 (F-box and WD repeat domain containing 8) Rattus norvegicus
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Symbol: Fbxw8
Name: F-box and WD repeat domain containing 8
Description: Predicted to contribute to ubiquitin-protein transferase activity. Involved in Golgi organization and positive regulation of dendrite morphogenesis. Localizes to the Golgi apparatus and perinuclear region of cytoplasm. Predicted to colocalize with the 3M complex. Orthologous to human FBXW8 (F-box and WD repeat domain containing 8); PARTICIPATES IN ubiquitin/proteasome degradation pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,6-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: F-box and WD-40 domain protein 8; F-box and WD-40 domain-containing protein 8; F-box/WD repeat-containing protein 8; LOC304522
Orthologs:
Homo sapiens (human) : FBXW8 (F-box and WD repeat domain containing 8)  HGNC  Alliance
Mus musculus (house mouse) : Fbxw8 (F-box and WD-40 domain protein 8)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fbxw8 (F-box and WD repeat domain containing 8)
Pan paniscus (bonobo/pygmy chimpanzee) : FBXW8 (F-box and WD repeat domain containing 8)
Canis lupus familiaris (dog) : FBXW8 (F-box and WD repeat domain containing 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fbxw8 (F-box and WD repeat domain containing 8)
Sus scrofa (pig) : FBXW8 (F-box and WD repeat domain containing 8)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01244,046,204 - 44,138,138 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01245,877,860 - 45,969,762 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41239,574,258 - 39,666,586 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11239,437,667 - 39,526,703 (+)NCBI
Celera1240,085,063 - 40,177,071 (+)NCBICelera
Cytogenetic Map12q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Fbxw8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1306032
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.