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Gene: Pus1 (pseudouridine synthase 1) Rattus norvegicus
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Symbol: Pus1
Name: pseudouridine synthase 1
Description: Predicted to have RNA binding activity; nuclear receptor transcription coactivator activity; and tRNA pseudouridine synthase activity. Predicted to be involved in mRNA pseudouridine synthesis; positive regulation of transcription by RNA polymerase II; and tRNA pseudouridine synthesis. Predicted to colocalize with the nuclear chromatin. Human ortholog(s) of this gene implicated in myopathy, lactic acidosis, and sideroblastic anemia 1. Orthologous to human PUS1 (pseudouridine synthase 1); INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC304567; MGC112655; pseudouridylate synthase 1; tRNA pseudouridine synthase A; tRNA pseudouridine synthase A, mitochondrial; tRNA pseudouridine(38-40) synthase; tRNA pseudouridylate synthase I; tRNA-uridine isomerase I
Orthologs:
Homo sapiens (human) : PUS1 (pseudouridine synthase 1)  HGNC  Alliance
Mus musculus (house mouse) : Pus1 (pseudouridine synthase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pus1 (pseudouridine synthase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PUS1 (pseudouridine synthase 1)
Canis lupus familiaris (dog) : PUS1 (pseudouridine synthase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pus1 (pseudouridine synthase 1)
Sus scrofa (pig) : PUS1 (pseudouridine synthase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01251,936,721 - 51,945,930 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1251,937,175 - 51,945,928 (+)Ensembl
Rnor_5.01253,675,092 - 53,684,281 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41246,024,978 - 46,033,733 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11245,889,104 - 45,897,858 (+)NCBI
Celera1247,439,849 - 47,448,604 (+)NCBICelera
Cytogenetic Map12q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Pus1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1311871
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.