Ung (uracil-DNA glycosylase) - Rat Genome Database

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Gene: Ung (uracil-DNA glycosylase) Rattus norvegicus
Analyze
Symbol: Ung
Name: uracil-DNA glycosylase
RGD ID: 1307200
Description: Enables uracil DNA N-glycosylase activity. Involved in base-excision repair and negative regulation of apoptotic process. Predicted to be located in nucleoplasm. Predicted to be active in mitochondrion and nucleus. Human ortholog(s) of this gene implicated in dysgammaglobulinemia and immunodeficiency with hyper IgM type 5. Orthologous to human UNG (uracil DNA glycosylase); PARTICIPATES IN base excision repair pathway; primary immunodeficiency pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC304577; MGC108922
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81248,145,838 - 48,154,789 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1248,145,838 - 48,155,257 (-)EnsemblGRCr8
mRatBN7.21242,485,276 - 42,494,217 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1242,485,276 - 42,494,206 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1243,652,469 - 43,660,684 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01244,266,059 - 44,274,274 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01243,326,576 - 43,334,791 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01248,246,593 - 48,255,547 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1248,246,569 - 48,254,822 (-)Ensemblrn6Rnor6.0
Rnor_5.01250,028,792 - 50,037,127 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41243,520,629 - 43,528,873 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1244,089,808 - 44,098,015 (-)NCBICelera
RGSC_v3.11243,384,016 - 43,392,261 (-)NCBI
Cytogenetic Map12q16NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-dexrazoxane  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
1H-pyrazole  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-methylcholine  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-phenylprop-2-enal  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-fluorouracil  (ISO)
acetamide  (EXP)
acetylsalicylic acid  (ISO)
afimoxifene  (ISO)
all-trans-retinoic acid  (ISO)
amphetamine  (EXP)
amphibole asbestos  (ISO)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
atrazine  (ISO)
azathioprine  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
beta-naphthoflavone  (ISO)
biphenyl-4-amine  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
calcitriol  (ISO)
cannabidiol  (ISO)
cantharidin  (ISO)
carbamazepine  (ISO)
chlorpromazine  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
corosolic acid  (ISO)
coumestrol  (ISO)
cyclophosphamide  (EXP)
cyclosporin A  (ISO)
cypermethrin  (ISO)
DDE  (ISO)
dexamethasone  (ISO)
diamminedichloroplatinum  (ISO)
diazinon  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
diclofenac  (ISO)
dihydroxyacetone  (ISO)
disodium selenite  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
Enterolactone  (ISO)
finasteride  (EXP)
floxuridine  (ISO)
flutamide  (EXP,ISO)
folic acid  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
furan  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glyphosate  (ISO)
hydrogen peroxide  (ISO)
idarubicin  (ISO)
indirubin-3'-monoxime  (ISO)
inulin  (ISO)
isoflurane  (ISO)
isoprenaline  (ISO)
isotretinoin  (ISO)
kojic acid  (ISO)
L-ascorbic acid  (ISO)
L-methionine  (ISO)
melatonin  (ISO)
menadione  (ISO)
methotrexate  (ISO)
mitomycin C  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
monocrotaline  (ISO)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
nefazodone  (EXP)
nickel dichloride  (ISO)
nimesulide  (EXP)
okadaic acid  (ISO)
ozone  (ISO)
paclitaxel  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenethyl isothiocyanate  (ISO)
phenobarbital  (EXP,ISO)
phenylmercury acetate  (ISO)
phenytoin  (ISO)
phosphoramide mustard  (EXP)
pirinixic acid  (ISO)
piroxicam  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (ISO)
raloxifene  (ISO)
resveratrol  (EXP,ISO)
rifampicin  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
succimer  (ISO)
sulindac  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (ISO)
transplatin  (ISO)
trichloroethene  (EXP)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
tunicamycin  (ISO)
uranium atom  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)
zinc pyrithione  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
mitochondrion  (IBA,IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IBA,IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Human uracil-DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination. Imai K, etal., Nat Immunol. 2003 Oct;4(10):1023-8. Epub 2003 Sep 7.
4. Suppression of uracil-DNA glycosylase induces neuronal apoptosis. Kruman II, etal., J Biol Chem. 2004 Oct 15;279(42):43952-60. Epub 2004 Aug 5.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Highly efficient base excision repair (BER) in human and rat male germ cells. Olsen AK, etal., Nucleic Acids Res. 2001 Apr 15;29(8):1781-90.
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. GOA pipeline RGD automated data pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
13. Expression and activity of the DNA repair enzyme uracil DNA glycosylase during organogenesis in the rat conceptus and following methotrexate exposure in vitro. Vinson RK and Hales BF, Biochem Pharmacol 2002 Aug 15;64(4):711-21.
Additional References at PubMed
PMID:10871356   PMID:12161446   PMID:14651853   PMID:15494304   PMID:17015724   PMID:18614015   PMID:18973764  


Genomics

Comparative Map Data
Ung
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81248,145,838 - 48,154,789 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1248,145,838 - 48,155,257 (-)EnsemblGRCr8
mRatBN7.21242,485,276 - 42,494,217 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1242,485,276 - 42,494,206 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1243,652,469 - 43,660,684 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01244,266,059 - 44,274,274 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01243,326,576 - 43,334,791 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01248,246,593 - 48,255,547 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1248,246,569 - 48,254,822 (-)Ensemblrn6Rnor6.0
Rnor_5.01250,028,792 - 50,037,127 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41243,520,629 - 43,528,873 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1244,089,808 - 44,098,015 (-)NCBICelera
RGSC_v3.11243,384,016 - 43,392,261 (-)NCBI
Cytogenetic Map12q16NCBI
UNG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812109,097,597 - 109,110,992 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12109,097,597 - 109,126,725 (+)Ensemblhg38GRCh38
GRCh3712109,535,402 - 109,548,797 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612108,019,798 - 108,033,181 (+)NCBIBuild 36Build 36hg18NCBI36
Build 3412107,998,134 - 108,011,518NCBI
Celera12109,159,338 - 109,172,962 (+)NCBICelera
Cytogenetic Map12q24.11NCBI
HuRef12106,553,817 - 106,567,575 (+)NCBIHuRef
CHM1_112109,503,049 - 109,516,448 (+)NCBICHM1_1
T2T-CHM13v2.012109,072,409 - 109,086,041 (+)NCBIT2T-CHM13v2.0
Ung
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395114,268,427 - 114,277,382 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5114,268,447 - 114,277,384 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm385114,130,366 - 114,139,321 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5114,130,386 - 114,139,323 (+)Ensemblmm10GRCm38
MGSCv375114,580,444 - 114,589,330 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv365114,392,199 - 114,418,049 (+)NCBIMGSCv36mm8
Celera5111,232,303 - 111,241,182 (+)NCBICelera
Cytogenetic Map5FNCBI
cM Map555.97NCBI
Ung
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545510,266,989 - 10,282,196 (+)Ensembl
ChiLan1.0NW_00495545510,266,989 - 10,282,196 (+)NCBIChiLan1.0ChiLan1.0
UNG
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210117,163,347 - 117,176,365 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112117,159,745 - 117,172,766 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012106,674,073 - 106,687,054 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112110,067,882 - 110,080,891 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12110,067,879 - 110,080,891 (+)EnsemblpanPan2panpan1.1
UNG
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12617,900,354 - 17,911,126 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2617,901,357 - 17,911,288 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2617,889,919 - 17,901,192 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02618,244,407 - 18,255,900 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2618,242,974 - 18,255,885 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12618,099,207 - 18,110,426 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02618,235,026 - 18,246,514 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02618,253,824 - 18,265,113 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ung
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118144,553,145 - 144,565,155 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936769910,838 - 922,726 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936769911,296 - 922,770 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UNG
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1441,746,502 - 41,757,807 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11441,746,498 - 41,757,841 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21444,311,840 - 44,323,500 (-)NCBISscrofa10.2Sscrofa10.2susScr3
UNG
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111104,302,507 - 104,325,160 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037140,779,094 - 140,801,492 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ung
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474712,261,623 - 12,274,859 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474712,261,546 - 12,275,229 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Ung
45 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:155
Count of miRNA genes:119
Interacting mature miRNAs:132
Transcripts:ENSRNOT00000056865
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631560Apr1Acute phase response QTL 16.1orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)121914436246669029Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
8693635Alc28Alcohol consumption QTL 282.70.439drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)122308134044726024Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
7411643Foco20Food consumption QTL 200.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)122032881946669029Rat
61324Eae5Experimental allergic encephalomyelitis QTL 514nervous system integrity trait (VT:0010566)percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time (CMO:0001402)121961087046669029Rat
5684888Pia42Pristane induced arthritis QTL 42joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)121961087042828880Rat
2302060Pia37Pristane induced arthritis QTL 376.10.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)121319815746669029Rat
1549912Bp268Blood pressure QTL 268arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)101318273646669029Rat
1300162Bp188Blood pressure QTL 1883.19arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)123210317445899022Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121281238546669029Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)12960327746669029Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449846669029Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)12610757946669029Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
1549902Bp269Blood pressure QTL 269arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)121318273646669029Rat
1600386Calcic2Intracellular calcium level QTL 20.001platelet physiology trait (VT:0005464)platelet intracellular calcium level (CMO:0000922)122806443346669029Rat
1302792Scl21Serum cholesterol level QTL 213.80.0011blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)12719673046669029Rat
1300175Cm5Cardiac mass QTL 53.78heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)122806443345899022Rat
61404Bw120Body weight QTL 1205.1body mass (VT:0001259)body mass index (BMI) (CMO:0000105)121235161946669029Rat
8693658Alc33Alcohol consumption QTL 332.10.68drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)122308134043551788Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121047413746669029Rat
1331761Bp218Blood pressure QTL 2182.973arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121107382545055165Rat
634351Apr5Acute phase response QTL 56.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)12144503507Rat
634350Apr4Acute phase response QTL 46orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)12117200546172005Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)6556449546669029Rat
737979Pia22Pristane induced arthritis QTL 2253.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12144465750Rat
2303569Gluco44Glucose level QTL 442blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121281238546669029Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
2302042Pia38Pristane induced arthritis QTL 383.50.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)12144503507Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121047413746669029Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat

Markers in Region
RH134515  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21242,485,430 - 42,485,628 (+)MAPPERmRatBN7.2
Rnor_6.01248,246,748 - 48,246,945NCBIRnor6.0
Rnor_5.01250,028,947 - 50,029,144UniSTSRnor5.0
RGSC_v3.41243,520,784 - 43,520,981UniSTSRGSC3.4
Celera1244,089,963 - 44,090,160UniSTS
Cytogenetic Map12q16UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 161 91 90 59 91 59 6 355 191 11 140 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000056865   ⟹   ENSRNOP00000053707
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1248,145,838 - 48,155,257 (-)Ensembl
mRatBN7.2 Ensembl1242,485,276 - 42,494,206 (-)Ensembl
Rnor_6.0 Ensembl1248,246,569 - 48,254,822 (-)Ensembl
RefSeq Acc Id: NM_001013124   ⟹   NP_001013142
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81248,145,838 - 48,154,045 (-)NCBI
mRatBN7.21242,485,276 - 42,493,484 (-)NCBI
Rnor_6.01248,246,593 - 48,254,800 (-)NCBI
Rnor_5.01250,028,792 - 50,037,127 (-)NCBI
RGSC_v3.41243,520,629 - 43,528,873 (-)RGD
Celera1244,089,808 - 44,098,015 (-)RGD
Sequence:
RefSeq Acc Id: XM_008769336   ⟹   XP_008767558
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81248,145,838 - 48,154,789 (-)NCBI
mRatBN7.21242,485,276 - 42,494,217 (-)NCBI
Rnor_6.01248,246,593 - 48,255,547 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001013142 (Get FASTA)   NCBI Sequence Viewer  
  XP_008767558 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH91211 (Get FASTA)   NCBI Sequence Viewer  
  EDM13948 (Get FASTA)   NCBI Sequence Viewer  
  EDM13949 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000053707.4
RefSeq Acc Id: NP_001013142   ⟸   NM_001013124
- UniProtKB: Q5BK44 (UniProtKB/TrEMBL),   F7F2G1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008767558   ⟸   XM_008769336
- Peptide Label: isoform X1
- UniProtKB: A0A8J8YLI4 (UniProtKB/TrEMBL),   A6J209 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000053707   ⟸   ENSRNOT00000056865
Protein Domains
Uracil-DNA glycosylase-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5BK44-F1-model_v2 AlphaFold Q5BK44 1-303 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698714
Promoter ID:EPDNEW_R9238
Type:multiple initiation site
Name:Ung_1
Description:uracil-DNA glycosylase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01248,254,783 - 48,254,843EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307200 AgrOrtholog
BioCyc Gene G2FUF-18940 BioCyc
Ensembl Genes ENSRNOG00000000692 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000056865.4 UniProtKB/TrEMBL
Gene3D-CATH 3.40.470.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7381643 IMAGE-MGC_LOAD
InterPro UDNA_glycsylse UniProtKB/TrEMBL
  Ura-DNA_Glyclase_AS UniProtKB/TrEMBL
  Uracil-DNA_glycosylase-like UniProtKB/TrEMBL
  Uracil-DNA_glycosylase-like_sf UniProtKB/TrEMBL
KEGG Report rno:304577 UniProtKB/TrEMBL
MGC_CLONE MGC:108922 IMAGE-MGC_LOAD
NCBI Gene 304577 ENTREZGENE
PANTHER UDNA_glycsylse UniProtKB/TrEMBL
  URACIL-DNA GLYCOSYLASE UniProtKB/TrEMBL
Pfam UDG UniProtKB/TrEMBL
PhenoGen Ung PhenoGen
PROSITE U_DNA_GLYCOSYLASE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000000692 RatGTEx
SMART UDG UniProtKB/TrEMBL
  UreE_C UniProtKB/TrEMBL
Superfamily-SCOP UDNA_glycsylseSF UniProtKB/TrEMBL
UniProt A0A8J8YLI4 ENTREZGENE, UniProtKB/TrEMBL
  A6J209 ENTREZGENE, UniProtKB/TrEMBL
  F7F2G1 ENTREZGENE
  Q5BK44 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary F7F2G1 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Ung  uracil-DNA glycosylase  Ung_predicted  uracil-DNA glycosylase (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Ung_predicted  uracil-DNA glycosylase (predicted)      Symbol and Name status set to approved 70820 APPROVED