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Gene: Gcn1 (GCN1 activator of EIF2AK4) Rattus norvegicus
Symbol: Gcn1
Name: GCN1 activator of EIF2AK4
Description: Predicted to have protein kinase binding activity; protein kinase regulator activity; and ribosome binding activity. Predicted to be involved in cellular response to leucine starvation and positive regulation of transcription from RNA polymerase II promoter in response to stress. Predicted to localize to the cytosol and polysome. Orthologous to human GCN1 (GCN1 activator of EIF2AK4); INTERACTS WITH (RS)-amphetamine; bisphenol A; pirinixic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: eIF-2-alpha kinase activator GCN1; GCN1 eIF2 alpha kinase activator-like 1; GCN1 general control of amino-acid synthesis 1-like 1; GCN1 general control of amino-acid synthesis 1-like 1 (yeast); GCN1, eIF2 alpha kinase activator homolog; Gcn1l1; LOC690632; similar to GCN1 general control of amino-acid synthesis 1-like 1; translational activator GCN1
Homo sapiens (human) : GCN1 (GCN1 activator of EIF2AK4)  HGNC  Alliance
Mus musculus (house mouse) : Gcn1 (GCN1 activator of EIF2AK4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gcn1 (GCN1, eIF2 alpha kinase activator homolog)
Pan paniscus (bonobo/pygmy chimpanzee) : GCN1 (GCN1, eIF2 alpha kinase activator homolog)
Canis lupus familiaris (dog) : GCN1 (GCN1 activator of EIF2AK4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gcn1 (GCN1, eIF2 alpha kinase activator homolog)
Sus scrofa (pig) : GCN1 (GCN1, eIF2 alpha kinase activator homolog)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01246,728,684 - 46,789,696 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01248,527,293 - 48,587,188 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41242,253,048 - 42,313,931 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1242,614,520 - 42,675,976 (-)NCBICelera
Cytogenetic Map12q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Gcn1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1593434
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.