Git2 (GIT ArfGAP 2) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Git2 (GIT ArfGAP 2) Rattus norvegicus
Analyze
Symbol: Git2
Name: GIT ArfGAP 2
RGD ID: 1359708
Description: Predicted to enable GTPase activator activity and small GTPase binding activity. Predicted to be involved in several processes, including modulation of chemical synaptic transmission; regulation of signal transduction; and synaptic vesicle recycling. Predicted to act upstream of or within behavioral response to pain. Predicted to be located in nucleoplasm and presynapse. Predicted to be active in calyx of Held. Orthologous to human GIT2 (GIT ArfGAP 2); PARTICIPATES IN endocytosis pathway; INTERACTS WITH 2,4,6-trinitrotoluene; 2,6-dinitrotoluene; atrazine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ARF GAP GIT2; ARF GTPase-activating protein GIT2; CAT-2; CAT2; cool-interacting tyrosine-phosphorylated protein 2; G protein-coupled receptor kinase interacting ArfGAP 2; G protein-coupled receptor kinase-interactor 2; GRK-interacting protein 2; MGC94099; similar to Git2 protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21241,829,717 - 41,872,621 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1241,829,730 - 41,871,097 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1242,997,345 - 43,038,116 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01243,610,923 - 43,651,694 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01242,671,415 - 42,712,186 (+)NCBIRnor_WKY
Rnor_6.01247,590,110 - 47,630,991 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1247,590,154 - 47,631,119 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01249,383,645 - 49,424,284 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41243,117,706 - 43,158,710 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11242,981,093 - 43,022,097 (+)NCBI
Celera1243,445,286 - 43,486,291 (+)NCBICelera
Cytogenetic Map12q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. A tyrosine-phosphorylated protein that binds to an important regulatory region on the cool family of p21-activated kinase-binding proteins. Bagrodia S, etal., J Biol Chem 1999 Aug 6;274(32):22393-400.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:10942595   PMID:17310244   PMID:19912111   PMID:21423176   PMID:22606319   PMID:23870131   PMID:26637799  


Genomics

Comparative Map Data
Git2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21241,829,717 - 41,872,621 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1241,829,730 - 41,871,097 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1242,997,345 - 43,038,116 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01243,610,923 - 43,651,694 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01242,671,415 - 42,712,186 (+)NCBIRnor_WKY
Rnor_6.01247,590,110 - 47,630,991 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1247,590,154 - 47,631,119 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01249,383,645 - 49,424,284 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41243,117,706 - 43,158,710 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11242,981,093 - 43,022,097 (+)NCBI
Celera1243,445,286 - 43,486,291 (+)NCBICelera
Cytogenetic Map12q16NCBI
GIT2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812109,929,804 - 110,000,164 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl12109,929,804 - 109,996,389 (-)EnsemblGRCh38hg38GRCh38
GRCh3712110,367,609 - 110,434,173 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612108,851,992 - 108,918,483 (-)NCBINCBI36Build 36hg18NCBI36
Build 3412108,848,588 - 108,896,820NCBI
Celera12109,991,955 - 110,058,428 (-)NCBICelera
Cytogenetic Map12q24.11NCBI
HuRef12107,383,692 - 107,449,937 (-)NCBIHuRef
CHM1_112110,335,391 - 110,401,989 (-)NCBICHM1_1
T2T-CHM13v2.012109,905,496 - 109,972,057 (-)NCBIT2T-CHM13v2.0
Git2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395114,865,469 - 114,912,647 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5114,865,468 - 114,913,578 (-)EnsemblGRCm39 Ensembl
GRCm385114,727,408 - 114,774,588 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5114,727,407 - 114,775,517 (-)EnsemblGRCm38mm10GRCm38
MGSCv375115,177,417 - 115,223,501 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365114,988,410 - 115,034,490 (-)NCBIMGSCv36mm8
Celera5111,825,622 - 111,871,698 (-)NCBICelera
Cytogenetic Map5FNCBI
Git2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554558,613,490 - 8,670,205 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554558,611,218 - 8,669,527 (+)NCBIChiLan1.0ChiLan1.0
GIT2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.112110,901,293 - 110,967,489 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12110,901,303 - 110,967,489 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v012107,505,791 - 107,572,641 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
GIT2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12617,170,651 - 17,217,634 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2617,170,680 - 17,214,631 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2618,584,319 - 18,631,531 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02617,515,164 - 17,562,316 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2617,515,162 - 17,562,313 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12618,794,107 - 18,841,098 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02617,504,924 - 17,552,144 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02617,522,393 - 17,569,401 (+)NCBIUU_Cfam_GSD_1.0
Git2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118143,901,711 - 143,948,385 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367691,527,151 - 1,574,892 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049367691,529,983 - 1,574,805 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GIT2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1440,995,988 - 41,051,902 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11440,995,986 - 41,051,896 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21443,511,566 - 43,567,474 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GIT2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111105,171,441 - 105,235,661 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11105,169,099 - 105,235,290 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037139,885,173 - 139,947,837 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Git2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474710,518,671 - 10,580,179 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474710,518,651 - 10,580,179 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Git2
231 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:286
Count of miRNA genes:187
Interacting mature miRNAs:206
Transcripts:ENSRNOT00000045946
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411660Foco28Food consumption QTL 2810.90.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
9590086Insglur6Insulin/glucose ratio QTL 618.970.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)12142110980Rat
8694179Bw150Body weight QTL 1502.90.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
7411586Foco5Food consumption QTL 55.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411595Foco9Food consumption QTL 940.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411545Bw128Body weight QTL 1285.20.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)12142110980Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12142450532Rat
737979Pia22Pristane induced arthritis QTL 2253.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12144465750Rat
634351Apr5Acute phase response QTL 56.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)12144503507Rat
2302042Pia38Pristane induced arthritis QTL 383.50.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)12144503507Rat
634350Apr4Acute phase response QTL 46orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)12117200546172005Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)6556449546669029Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449846669029Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)12610757946669029Rat
1302792Scl21Serum cholesterol level QTL 213.80.0011blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)12719673046669029Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)12960327746669029Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121047413746669029Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121047413746669029Rat
1331761Bp218Blood pressure QTL 2182.973arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121107382545055165Rat
61404Bw120Body weight QTL 1205.1body mass (VT:0001259)body mass index (BMI) (CMO:0000105)121235161946669029Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121281238546669029Rat
2303569Gluco44Glucose level QTL 442blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121281238546669029Rat
1549902Bp269Blood pressure QTL 269arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)121318273646669029Rat
1549912Bp268Blood pressure QTL 268arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)101318273646669029Rat
2302060Pia37Pristane induced arthritis QTL 376.10.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)121319815746669029Rat
631560Apr1Acute phase response QTL 16.1orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)121914436246669029Rat
5684888Pia42Pristane induced arthritis QTL 42joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)121961087042828880Rat
61324Eae5Experimental allergic encephalomyelitis QTL 514nervous system integrity trait (VT:0010566)percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time (CMO:0001402)121961087046669029Rat
7411643Foco20Food consumption QTL 200.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)122032881946669029Rat
1300175Cm5Cardiac mass QTL 53.78heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)122806443345899022Rat
1600386Calcic2Intracellular calcium level QTL 20.001platelet physiology trait (VT:0005464)platelet intracellular calcium level (CMO:0000922)122806443346669029Rat
1300162Bp188Blood pressure QTL 1883.19arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)123210317445899022Rat

Markers in Region
RH132951  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21241,844,122 - 41,844,307 (+)MAPPERmRatBN7.2
Rnor_6.01247,604,513 - 47,604,697NCBIRnor6.0
Rnor_5.01249,398,038 - 49,398,222UniSTSRnor5.0
RGSC_v3.41243,132,055 - 43,132,239UniSTSRGSC3.4
Celera1243,459,635 - 43,459,819UniSTS
RH 3.4 Map12781.83UniSTS
Cytogenetic Map12q16UniSTS
BE120218  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21241,842,950 - 41,843,127 (+)MAPPERmRatBN7.2
Rnor_6.01247,603,341 - 47,603,517NCBIRnor6.0
Rnor_5.01249,396,866 - 49,397,042UniSTSRnor5.0
RGSC_v3.41243,130,883 - 43,131,059UniSTSRGSC3.4
Celera1243,458,463 - 43,458,639UniSTS
RH 3.4 Map12779.53UniSTS
Cytogenetic Map12q16UniSTS
AI511444  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21241,870,248 - 41,870,453 (+)MAPPERmRatBN7.2
Rnor_6.01247,630,639 - 47,630,843NCBIRnor6.0
Rnor_5.01249,423,932 - 49,424,136UniSTSRnor5.0
RGSC_v3.41243,158,358 - 43,158,562UniSTSRGSC3.4
Celera1243,485,939 - 43,486,143UniSTS
Cytogenetic Map12q16UniSTS
RH139528  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21241,868,466 - 41,868,664 (+)MAPPERmRatBN7.2
Rnor_6.01247,628,857 - 47,629,054NCBIRnor6.0
Rnor_5.01249,422,150 - 49,422,347UniSTSRnor5.0
RGSC_v3.41243,156,576 - 43,156,773UniSTSRGSC3.4
Celera1243,484,157 - 43,484,354UniSTS
Cytogenetic Map12q16UniSTS
RH140364  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21241,868,504 - 41,868,664 (+)MAPPERmRatBN7.2
Rnor_6.01247,628,895 - 47,629,054NCBIRnor6.0
Rnor_5.01249,422,188 - 49,422,347UniSTSRnor5.0
RGSC_v3.41243,156,614 - 43,156,773UniSTSRGSC3.4
Celera1243,484,195 - 43,484,354UniSTS
RH 3.4 Map12778.12UniSTS
Cytogenetic Map12q16UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 56 40 19 40 6 7 74 35 41 11 6
Low 1 1 1 2 4 2
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001005553 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006249442 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006249445 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006249447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006249450 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598345 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598346 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598347 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598349 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598350 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598351 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005491630 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC095845 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC081967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473973 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ235304 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000229 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000045946   ⟹   ENSRNOP00000048331
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1241,829,746 - 41,870,601 (+)Ensembl
Rnor_6.0 Ensembl1247,590,154 - 47,631,119 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000096072   ⟹   ENSRNOP00000086491
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1241,829,773 - 41,870,600 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000097577   ⟹   ENSRNOP00000081139
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1241,829,730 - 41,871,097 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000100352   ⟹   ENSRNOP00000093537
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1241,829,773 - 41,870,600 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000105617   ⟹   ENSRNOP00000079644
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1241,833,224 - 41,870,600 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000108942   ⟹   ENSRNOP00000080405
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1241,829,746 - 41,870,600 (+)Ensembl
RefSeq Acc Id: NM_001005553   ⟹   NP_001005553
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21241,829,773 - 41,870,601 (+)NCBI
Rnor_6.01247,590,164 - 47,630,991 (+)NCBI
Rnor_5.01249,383,645 - 49,424,284 (+)NCBI
RGSC_v3.41243,117,706 - 43,158,710 (+)RGD
Celera1243,445,286 - 43,486,291 (+)RGD
Sequence:
RefSeq Acc Id: XM_006249442   ⟹   XP_006249504
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21241,829,722 - 41,872,621 (+)NCBI
Rnor_6.01247,590,110 - 47,630,991 (+)NCBI
Rnor_5.01249,383,645 - 49,424,284 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006249445   ⟹   XP_006249507
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21241,829,722 - 41,872,621 (+)NCBI
Rnor_6.01247,590,111 - 47,630,991 (+)NCBI
Rnor_5.01249,383,645 - 49,424,284 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006249447   ⟹   XP_006249509
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21241,829,722 - 41,872,621 (+)NCBI
Rnor_6.01247,590,111 - 47,630,991 (+)NCBI
Rnor_5.01249,383,645 - 49,424,284 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006249450   ⟹   XP_006249512
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21241,829,723 - 41,872,621 (+)NCBI
Rnor_6.01247,590,111 - 47,630,991 (+)NCBI
Rnor_5.01249,383,645 - 49,424,284 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017598345   ⟹   XP_017453834
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21241,829,721 - 41,872,621 (+)NCBI
Rnor_6.01247,590,110 - 47,630,991 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017598346   ⟹   XP_017453835
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21241,829,721 - 41,872,621 (+)NCBI
Rnor_6.01247,590,110 - 47,630,991 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017598347   ⟹   XP_017453836
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21241,829,721 - 41,872,621 (+)NCBI
Rnor_6.01247,590,110 - 47,630,991 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017598348   ⟹   XP_017453837
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21241,829,722 - 41,872,621 (+)NCBI
Rnor_6.01247,590,111 - 47,630,991 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017598349   ⟹   XP_017453838
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21241,829,722 - 41,872,621 (+)NCBI
Rnor_6.01247,590,111 - 47,630,991 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017598350   ⟹   XP_017453839
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21241,829,722 - 41,872,621 (+)NCBI
Rnor_6.01247,590,111 - 47,630,991 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017598351   ⟹   XP_017453840
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21241,829,722 - 41,872,621 (+)NCBI
Rnor_6.01247,590,111 - 47,630,991 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039089502   ⟹   XP_038945430
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21241,829,717 - 41,872,621 (+)NCBI
RefSeq Acc Id: XR_005491630
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21241,829,721 - 41,872,621 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_001005553   ⟸   NM_001005553
- UniProtKB: Q66H91 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006249507   ⟸   XM_006249445
- Peptide Label: isoform X6
- UniProtKB: A0A8I6A5F6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006249512   ⟸   XM_006249450
- Peptide Label: isoform X12
- Sequence:
RefSeq Acc Id: XP_006249504   ⟸   XM_006249442
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006249509   ⟸   XM_006249447
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_017453834   ⟸   XM_017598345
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017453836   ⟸   XM_017598347
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_017453835   ⟸   XM_017598346
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017453837   ⟸   XM_017598348
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_017453838   ⟸   XM_017598349
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_017453839   ⟸   XM_017598350
- Peptide Label: isoform X10
- UniProtKB: A0A8I6G6J8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017453840   ⟸   XM_017598351
- Peptide Label: isoform X11
- Sequence:
RefSeq Acc Id: ENSRNOP00000048331   ⟸   ENSRNOT00000045946
RefSeq Acc Id: XP_038945430   ⟸   XM_039089502
- Peptide Label: isoform X9
RefSeq Acc Id: ENSRNOP00000081139   ⟸   ENSRNOT00000097577
RefSeq Acc Id: ENSRNOP00000086491   ⟸   ENSRNOT00000096072
RefSeq Acc Id: ENSRNOP00000080405   ⟸   ENSRNOT00000108942
RefSeq Acc Id: ENSRNOP00000079644   ⟸   ENSRNOT00000105617
RefSeq Acc Id: ENSRNOP00000093537   ⟸   ENSRNOT00000100352
Protein Domains
Arf-GAP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q66H91-F1-model_v2 AlphaFold Q66H91 1-759 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698707
Promoter ID:EPDNEW_R9232
Type:initiation region
Name:Git2_1
Description:GIT ArfGAP 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01247,590,129 - 47,590,189EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359708 AgrOrtholog
BioCyc Gene G2FUF-18959 BioCyc
Ensembl Genes ENSRNOG00000001190 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000048331 ENTREZGENE
  ENSRNOP00000048331.3 UniProtKB/TrEMBL
  ENSRNOP00000079644.1 UniProtKB/TrEMBL
  ENSRNOP00000080405 ENTREZGENE
  ENSRNOP00000080405.1 UniProtKB/TrEMBL
  ENSRNOP00000081139.1 UniProtKB/TrEMBL
  ENSRNOP00000086491 ENTREZGENE
  ENSRNOP00000086491.1 UniProtKB/TrEMBL
  ENSRNOP00000093537.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000045946 ENTREZGENE
  ENSRNOT00000045946.4 UniProtKB/TrEMBL
  ENSRNOT00000096072 ENTREZGENE
  ENSRNOT00000096072.1 UniProtKB/TrEMBL
  ENSRNOT00000097577.1 UniProtKB/TrEMBL
  ENSRNOT00000100352.1 UniProtKB/TrEMBL
  ENSRNOT00000105617.1 UniProtKB/TrEMBL
  ENSRNOT00000108942 ENTREZGENE
  ENSRNOT00000108942.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.220.150 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.25.40.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7125406 IMAGE-MGC_LOAD
InterPro Ankyrin_rpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ARFGAP/RecO UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ArfGAP_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ArfGAP_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GIT1/2_CC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GIT1_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GIT_SHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:304546 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94099 IMAGE-MGC_LOAD
NCBI Gene 304546 ENTREZGENE
Pfam Ank_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ArfGap UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GIT1_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GIT_CC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GIT_SHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Git2 PhenoGen
PRINTS REVINTRACTNG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ANK_REP_REGION UniProtKB/Swiss-Prot
  ANK_REPEAT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ARFGAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART ANK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ArfGap UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GIT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48403 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57863 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZN29_RAT UniProtKB/TrEMBL
  A0A8I5ZRU3_RAT UniProtKB/TrEMBL
  A0A8I6A5F6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ALK4_RAT UniProtKB/TrEMBL
  A0A8I6G6J8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2UM41_RAT UniProtKB/TrEMBL
  GIT2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-22 Git2  GIT ArfGAP 2  Git2  G protein-coupled receptor kinase interacting ArfGAP 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-23 Git2  G protein-coupled receptor kinase interacting ArfGAP 2  Git2  G protein-coupled receptor kinase-interactor 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Git2  G protein-coupled receptor kinase-interactor 2  MGC94099  similar to Git2 protein  Symbol and Name updated 1299863 APPROVED
2005-07-29 MGC94099  similar to Git2 protein      Symbol and Name status set to provisional 70820 PROVISIONAL