Hscb (HscB mitochondrial iron-sulfur cluster co-chaperone) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Hscb (HscB mitochondrial iron-sulfur cluster co-chaperone) Rattus norvegicus
Analyze
Symbol: Hscb
Name: HscB mitochondrial iron-sulfur cluster co-chaperone
RGD ID: 1311005
Description: Predicted to enable identical protein binding activity. Predicted to be involved in [2Fe-2S] cluster assembly and primitive erythrocyte differentiation. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in sideroblastic anemia. Orthologous to human HSCB (HscB mitochondrial iron-sulfur cluster cochaperone); PARTICIPATES IN mitochondrial iron-sulfur cluster protein biogenesis pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; diuron.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: HscB iron-sulfur cluster co-chaperone homolog; HscB iron-sulfur cluster co-chaperone homolog (E. coli); iron-sulfur cluster co-chaperone protein HscB; iron-sulfur cluster co-chaperone protein HscB, mitochondrial; LOC360826; RGD1311005; similar to J-type co-chaperone HSC20
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21245,821,527 - 45,831,902 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1245,821,555 - 45,831,909 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01251,878,267 - 51,888,645 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1251,878,153 - 51,888,669 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01253,616,638 - 53,626,996 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41245,966,103 - 45,976,448 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11245,829,995 - 45,840,566 (+)NCBI
Celera1247,381,162 - 47,391,328 (+)NCBICelera
Cytogenetic Map12q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (ISO)
cytosol  (ISO)
mitochondrion  (IBA,ISO)
nucleoplasm  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Iron-sulfur cluster biogenesis in mammalian cells: New insights into the molecular mechanisms of cluster delivery. Maio N and Rouault TA, Biochim Biophys Acta. 2015 Jun;1853(6):1493-512. doi: 10.1016/j.bbamcr.2014.09.009. Epub 2014 Sep 19.
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:18614015   PMID:20668094   PMID:24606901  


Genomics

Comparative Map Data
Hscb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21245,821,527 - 45,831,902 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1245,821,555 - 45,831,909 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01251,878,267 - 51,888,645 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1251,878,153 - 51,888,669 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01253,616,638 - 53,626,996 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41245,966,103 - 45,976,448 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11245,829,995 - 45,840,566 (+)NCBI
Celera1247,381,162 - 47,391,328 (+)NCBICelera
Cytogenetic Map12q16NCBI
HSCB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382228,742,032 - 28,757,510 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl2228,742,039 - 28,757,515 (+)EnsemblGRCh38hg38GRCh38
GRCh372229,138,020 - 29,153,498 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362227,468,043 - 27,483,498 (+)NCBINCBI36Build 36hg18NCBI36
Celera2212,938,022 - 12,953,467 (+)NCBICelera
Cytogenetic Map22q12.1NCBI
HuRef2212,103,229 - 12,118,689 (+)NCBIHuRef
CHM1_12229,097,104 - 29,112,531 (+)NCBICHM1_1
T2T-CHM13v2.02229,203,667 - 29,219,144 (+)NCBIT2T-CHM13v2.0
Hscb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395110,976,936 - 110,987,673 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5110,976,936 - 110,987,643 (-)EnsemblGRCm39 Ensembl
GRCm385110,829,070 - 110,839,793 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5110,829,070 - 110,839,777 (-)EnsemblGRCm38mm10GRCm38
MGSCv375111,258,089 - 111,268,796 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365111,069,372 - 111,080,043 (-)NCBIMGSCv36mm8
Celera5107,960,954 - 107,971,868 (-)NCBICelera
Cytogenetic Map5FNCBI
Hscb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554553,005,617 - 3,013,393 (+)NCBIChiLan1.0ChiLan1.0
HSCB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12227,512,557 - 27,528,198 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2227,512,564 - 27,527,914 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0229,811,294 - 9,826,245 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
HSCB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12622,103,803 - 22,120,200 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2622,103,845 - 22,120,198 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2621,975,398 - 21,991,803 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02622,476,999 - 22,493,407 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2622,477,046 - 22,493,422 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12622,187,261 - 22,203,642 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02622,450,893 - 22,467,277 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02622,513,309 - 22,529,793 (+)NCBIUU_Cfam_GSD_1.0
Hscb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118113,010,592 - 113,022,431 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049366572,848,282 - 2,860,115 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HSCB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1445,967,502 - 45,980,622 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11445,967,460 - 45,980,632 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
HSCB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11911,621,205 - 11,639,750 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1911,621,420 - 11,636,396 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045114,517,448 - 114,532,613 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hscb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247475,072,708 - 5,094,404 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Position Markers
RH134477  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21245,831,458 - 45,831,676 (+)MAPPERmRatBN7.2
Rnor_6.01251,888,202 - 51,888,419NCBIRnor6.0
Rnor_5.01253,626,553 - 53,626,770UniSTSRnor5.0
RGSC_v3.41245,976,005 - 45,976,222UniSTSRGSC3.4
Celera1247,390,885 - 47,391,102UniSTS
RH 3.4 Map12812.51UniSTS
Cytogenetic Map12q16UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634350Apr4Acute phase response QTL 46orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)12117200546172005Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)6556449546669029Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449846669029Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)12610757946669029Rat
1302792Scl21Serum cholesterol level QTL 213.80.0011blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)12719673046669029Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)12960327746669029Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121047413746669029Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121047413746669029Rat
61404Bw120Body weight QTL 1205.1body mass (VT:0001259)body mass index (BMI) (CMO:0000105)121235161946669029Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121281238546669029Rat
2303569Gluco44Glucose level QTL 442blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121281238546669029Rat
1549902Bp269Blood pressure QTL 269arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)121318273646669029Rat
1549912Bp268Blood pressure QTL 268arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)101318273646669029Rat
2302060Pia37Pristane induced arthritis QTL 376.10.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)121319815746669029Rat
631560Apr1Acute phase response QTL 16.1orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)121914436246669029Rat
61324Eae5Experimental allergic encephalomyelitis QTL 514nervous system integrity trait (VT:0010566)percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time (CMO:0001402)121961087046669029Rat
7411643Foco20Food consumption QTL 200.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)122032881946669029Rat
1300175Cm5Cardiac mass QTL 53.78heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)122806443345899022Rat
1600386Calcic2Intracellular calcium level QTL 20.001platelet physiology trait (VT:0005464)platelet intracellular calcium level (CMO:0000922)122806443346669029Rat
1300162Bp188Blood pressure QTL 1883.19arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)123210317445899022Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:8
Count of miRNA genes:8
Interacting mature miRNAs:8
Transcripts:ENSRNOT00000056798
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 33 45 29 19 29 2 2 74 30 34 11 2
Low 10 12 12 12 6 9 5 7 6
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000056798   ⟹   ENSRNOP00000053641
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1245,821,555 - 45,831,902 (+)Ensembl
Rnor_6.0 Ensembl1251,878,153 - 51,888,669 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000096303   ⟹   ENSRNOP00000083969
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1245,821,555 - 45,831,909 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000102335   ⟹   ENSRNOP00000085570
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1245,821,555 - 45,831,909 (+)Ensembl
RefSeq Acc Id: NM_001108340   ⟹   NP_001101810
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21245,821,555 - 45,831,902 (+)NCBI
Rnor_6.01251,878,300 - 51,888,645 (+)NCBI
Rnor_5.01253,616,638 - 53,626,996 (+)NCBI
RGSC_v3.41245,966,103 - 45,976,448 (+)RGD
Celera1247,381,162 - 47,391,328 (+)RGD
Sequence:
RefSeq Acc Id: XM_006249564   ⟹   XP_006249626
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21245,821,527 - 45,831,898 (+)NCBI
Rnor_6.01251,878,268 - 51,888,642 (+)NCBI
Rnor_5.01253,616,638 - 53,626,996 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008769340   ⟹   XP_008767562
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21245,821,527 - 45,831,892 (+)NCBI
Rnor_6.01251,878,267 - 51,888,591 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039089614   ⟹   XP_038945542
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21245,821,528 - 45,828,939 (+)NCBI
RefSeq Acc Id: XM_039089615   ⟹   XP_038945543
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21245,821,528 - 45,831,838 (+)NCBI
RefSeq Acc Id: XM_039089616   ⟹   XP_038945544
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21245,821,527 - 45,826,709 (+)NCBI
RefSeq Acc Id: XM_039089617   ⟹   XP_038945545
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21245,821,528 - 45,831,892 (+)NCBI
RefSeq Acc Id: XM_039089618   ⟹   XP_038945546
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21245,821,528 - 45,831,893 (+)NCBI
RefSeq Acc Id: XR_005491650
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21245,821,528 - 45,831,893 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_001101810   ⟸   NM_001108340
- Peptide Label: precursor
- UniProtKB: D3ZME7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006249626   ⟸   XM_006249564
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_008767562   ⟸   XM_008769340
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000053641   ⟸   ENSRNOT00000056798
RefSeq Acc Id: XP_038945544   ⟸   XM_039089616
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038945546   ⟸   XM_039089618
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038945545   ⟸   XM_039089617
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038945543   ⟸   XM_039089615
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038945542   ⟸   XM_039089614
- Peptide Label: isoform X3
RefSeq Acc Id: ENSRNOP00000085570   ⟸   ENSRNOT00000102335
RefSeq Acc Id: ENSRNOP00000083969   ⟸   ENSRNOT00000096303
Protein Domains
J

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZME7-F1-model_v2 AlphaFold D3ZME7 1-234 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698733
Promoter ID:EPDNEW_R9257
Type:initiation region
Name:Hscb_1
Description:HscB mitochondrial iron-sulfur cluster co-chaperone
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01251,878,321 - 51,878,381EPDNEW

Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311005 AgrOrtholog
BioCyc Gene G2FUF-18827 BioCyc
Ensembl Genes ENSRNOG00000037508 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000053641 ENTREZGENE
  ENSRNOP00000053641.2 UniProtKB/TrEMBL
  ENSRNOP00000083969 ENTREZGENE
  ENSRNOP00000083969.1 UniProtKB/TrEMBL
  ENSRNOP00000085570 ENTREZGENE
  ENSRNOP00000085570.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000056798 ENTREZGENE
  ENSRNOT00000056798.4 UniProtKB/TrEMBL
  ENSRNOT00000096303 ENTREZGENE
  ENSRNOT00000096303.1 UniProtKB/TrEMBL
  ENSRNOT00000102335 ENTREZGENE
  ENSRNOT00000102335.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.110 UniProtKB/TrEMBL
  1.20.1280.20 UniProtKB/TrEMBL
InterPro DnaJ_dom_sf UniProtKB/TrEMBL
  DnaJ_N UniProtKB/TrEMBL
  Heat_shock_cognate_B_oligo_C UniProtKB/TrEMBL
  HscB UniProtKB/TrEMBL
  HscB_4_cys UniProtKB/TrEMBL
  HscB_C_sf UniProtKB/TrEMBL
KEGG Report rno:360826 UniProtKB/TrEMBL
NCBI Gene 360826 ENTREZGENE
PANTHER PTHR14021 UniProtKB/TrEMBL
Pfam HscB_4_cys UniProtKB/TrEMBL
  HSCB_C UniProtKB/TrEMBL
PhenoGen Hscb PhenoGen
PROSITE DNAJ_2 UniProtKB/TrEMBL
SMART DnaJ UniProtKB/TrEMBL
Superfamily-SCOP DnaJ_N UniProtKB/TrEMBL
  HSC20_C UniProtKB/TrEMBL
TIGRFAMs hscB UniProtKB/TrEMBL
UniProt A0A8I5ZYF5_RAT UniProtKB/TrEMBL
  A0A8I6A2K9_RAT UniProtKB/TrEMBL
  D3ZME7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-09-18 Hscb  HscB mitochondrial iron-sulfur cluster co-chaperone  Hscb  HscB iron-sulfur cluster co-chaperone homolog (E. coli)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-27 Hscb  HscB iron-sulfur cluster co-chaperone homolog (E. coli)  RGD1311005_predicted  similar to J-type co-chaperone HSC20 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 RGD1311005_predicted  similar to J-type co-chaperone HSC20 (predicted)  LOC360826_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC360826_predicted  similar to J-type co-chaperone HSC20 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL