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Gene: Hrk (harakiri, BCL2 interacting protein) Rattus norvegicus
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Symbol: Hrk
Name: harakiri, BCL2 interacting protein
Description: Involved in apoptotic process; cellular response to potassium ion starvation; and positive regulation of neuron apoptotic process. Predicted to localize to the mitochondrion. Orthologous to human HRK (harakiri, BCL2 interacting protein); PARTICIPATES IN intrinsic apoptotic pathway; INTERACTS WITH (+)-pilocarpine; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: activator of apoptosis harakiri; BH3 interacting (with BCL2 family) domain apoptosis agonist; BH3 interacting (with BCL2 family) domain, apoptosis agonist; BH3 interacting domain 3; BH3-interacting domain-containing protein 3; Bid3; Dp5; harakiri, BCL2 interacting protein (contains only BH3 domain); neuronal death protein DP5
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly; Note: NM_057130.4 is based on transcript and protein alignment data, and may not be a true representation of the structure of GeneID 117271 due to the incomplete nature of the assembly in this region of the genome. [10 Oct 2014]
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01244,008,879 - 44,029,211 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01245,839,708 - 45,861,437 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41239,520,265 - 39,543,901 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11239,383,652 - 39,407,289 (-)NCBI
Celera1240,046,737 - 40,068,164 (-)NCBICelera
Cytogenetic Map12q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Hrk
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 70549
Created: 2002-05-20
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.