Gene: HVCN1 (hydrogen voltage gated channel 1) Homo sapiens
Symbol: HVCN1
Name: hydrogen voltage gated channel 1
Description: This gene encodes a voltage-gated protein channel protein expressed more highly in certain cells of the immune system. Phagocytic cells produce superoxide anions which require this channel protein, and in B cells this same process facilitates antibody production. This same channel protein, however, can also regulate functions in other cells including spermatozoa. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: HV1; hydrogen voltage-gated channel 1; MGC15619; voltage sensor domain-only protein; voltage-gated hydrogen channel 1; VSOP
Mus musculus (house mouse) : Hvcn1 (hydrogen voltage-gated channel 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Hvcn1 (hydrogen voltage-gated channel 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hvcn1 (hydrogen voltage gated channel 1)
Pan paniscus (bonobo/pygmy chimpanzee) : HVCN1 (hydrogen voltage gated channel 1)
Canis lupus familiaris (dog) : HVCN1 (hydrogen voltage gated channel 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hvcn1 (hydrogen voltage gated channel 1)
Sus scrofa (pig) : HVCN1 (hydrogen voltage gated channel 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh3812110,648,686 - 110,704,945 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3712111,086,491 - 111,130,276 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612109,570,874 - 109,612,000 (-)NCBINCBI36hg18NCBI36
Celera12110,713,319 - 110,754,445 (-)NCBI
Cytogenetic Map12q24.11NCBI
HuRef12108,104,197 - 108,145,322 (-)NCBIHuRef
CHM1_112111,054,153 - 111,095,269 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on HVCN1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1603943
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-02-19
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.