Bmal1 (basic helix-loop-helix ARNT like 1) - Rat Genome Database

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Gene: Bmal1 (basic helix-loop-helix ARNT like 1) Rattus norvegicus
Analyze
Symbol: Bmal1 (Ensembl: Arntl)
Name: basic helix-loop-helix ARNT like 1 (Ensembl:aryl hydrocarbon receptor nuclear translocator-like)
RGD ID: 62003
Description: Predicted to enable several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor binding activity; and E-box binding activity. Involved in circadian rhythm and positive regulation of DNA-templated transcription. Located in nucleus. Biomarker of cholestasis. Orthologous to human BMAL1 (basic helix-loop-helix ARNT like 1); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Arntl; aryl hydrocarbon receptor nuclear translocator-like; aryl hydrocarbon receptor nuclear translocator-like protein 1; basic helix-loop-helix ARNT-like protein 1; brain and muscle ARNT-like 1; tic
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: Bmal1em1Mcwi  
Genetic Models: SD-Bmal1em1Mcwi
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21167,331,756 - 167,430,235 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1167,331,633 - 167,430,231 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1175,666,810 - 175,765,622 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01182,852,900 - 182,951,712 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01175,548,108 - 175,646,871 (+)NCBIRnor_WKY
Rnor_6.01178,039,002 - 178,137,469 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1178,039,063 - 178,137,465 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01185,007,527 - 185,105,413 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41171,062,181 - 171,162,426 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11171,251,951 - 171,282,040 (+)NCBI
Celera1165,202,275 - 165,299,946 (+)NCBICelera
Cytogenetic Map1q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-epicatechin-3-O-gallate  (ISO)
(+)-schisandrin B  (EXP)
(-)-epigallocatechin 3-gallate  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
acrylamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-naphthoflavone  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bromobenzene  (EXP)
C60 fullerene  (EXP)
cadmium dichloride  (EXP)
carmustine  (EXP)
CGP 52608  (ISO)
CGS-21680  (ISO)
chloroprene  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
cortisol  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
dioxygen  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
flavonoids  (EXP)
gadolinium atom  (ISO)
gadolinium trichloride  (ISO)
gallic acid  (ISO)
gallocatechin  (ISO)
geraniol  (ISO)
hydrogen peroxide  (ISO)
indole-3-methanol  (EXP)
indometacin  (ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
manganese(II) chloride  (EXP)
melatonin  (EXP)
metformin  (EXP)
methotrexate  (EXP,ISO)
milrinone  (EXP)
N-acetyl-L-cysteine  (EXP)
N-nitrosodiethylamine  (EXP)
paraquat  (EXP)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (EXP)
potassium chromate  (ISO)
prednisolone  (ISO)
progesterone  (ISO)
quercetin  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
Se-methyl-L-selenocysteine  (EXP)
Se-methylselenocysteine  (EXP)
sevoflurane  (EXP)
silicon dioxide  (EXP)
sodium arsenite  (ISO)
sunitinib  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
tioguanine  (EXP)
titanium dioxide  (EXP)
triphenyl phosphate  (EXP)
tris(2-butoxyethyl) phosphate  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Mop3 is an essential component of the master circadian pacemaker in mammals. Bunger MK, etal., Cell 2000 Dec 22;103(7):1009-17.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Circadian oscillation of BMAL1, a partner of a mammalian clock gene Clock, in rat suprachiasmatic nucleus. Honma S, etal., Biochem Biophys Res Commun 1998 Sep 8;250(1):83-7.
5. Diurnal Control of Blood Pressure Is Uncoupled From Sodium Excretion. Johnston JG, etal., Hypertension. 2020 Jun;75(6):1624-1634. doi: 10.1161/HYPERTENSIONAHA.119.13908. Epub 2020 Apr 20.
6. Early aging and age-related pathologies in mice deficient in BMAL1, the core componentof the circadian clock. Kondratov RV, etal., Genes Dev. 2006 Jul 15;20(14):1868-73.
7. [Changes of biological clock protein in neonatal rats with hypoxic-ischemic brain damage]. Li YF, etal., Zhongguo Dang Dai Er Ke Za Zhi. 2013 Jan;15(1):62-6.
8. Thyroid transcription factor 1, a homeodomain containing transcription factor, contributes to regulating periodic oscillations in GnRH gene expression. Matagne V, etal., J Neuroendocrinol. 2012 Jun;24(6):916-29. doi: 10.1111/j.1365-2826.2012.02302.x.
9. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
10. The adipocyte clock controls brown adipogenesis through the TGF-beta and BMP signaling pathways. Nam D, etal., J Cell Sci. 2015 May 1;128(9):1835-47. doi: 10.1242/jcs.167643. Epub 2015 Mar 6.
11. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
12. Antiphase circadian expression between BMAL1 and period homologue mRNA in the suprachiasmatic nucleus and peripheral tissues of rats. Oishi K, etal., Biochem Biophys Res Commun. 1998 Dec 18;253(2):199-203.
13. Increased melatonin synthesis in pineal glands of rats in streptozotocin induced type 1 diabetes. Peschke E, etal., J Pineal Res. 2008 Jul 1.
14. Melatonin inhibits cholangiocyte hyperplasia in cholestatic rats by interaction with MT1 but not MT2 melatonin receptors. Renzi A, etal., Am J Physiol Gastrointest Liver Physiol. 2011 Oct;301(4):G634-43. doi: 10.1152/ajpgi.00206.2011. Epub 2011 Jul 14.
15. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
16. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
17. Cloning and chromosomal localization of a new member of the bHLH/PAS transcription factor family. Wolting CD and McGlade CJ, Mamm Genome 1998 Jun;9(6):463-8.
Additional References at PubMed
PMID:9079689   PMID:9576906   PMID:9704006   PMID:11441146   PMID:12024206   PMID:12150932   PMID:12397359   PMID:12477932   PMID:12738229   PMID:12843397   PMID:12897057   PMID:14645221  
PMID:14672706   PMID:15147242   PMID:15193144   PMID:15560782   PMID:16606840   PMID:17264215   PMID:17728404   PMID:17823250   PMID:18208549   PMID:18316400   PMID:18644859   PMID:19141540  
PMID:19217292   PMID:19299583   PMID:19387896   PMID:19605937   PMID:19740747   PMID:20093779   PMID:20106950   PMID:20430893   PMID:20562852   PMID:20861012   PMID:21113167   PMID:21613214  
PMID:21628546   PMID:21680841   PMID:21768648   PMID:21952132   PMID:22101268   PMID:22208286   PMID:22611086   PMID:22653727   PMID:22697126   PMID:22894897   PMID:22900038   PMID:22940729  
PMID:22960268   PMID:23056261   PMID:23263459   PMID:23395176   PMID:23525013   PMID:23596172   PMID:23738784   PMID:23785138   PMID:23831463   PMID:24005054   PMID:24043798   PMID:24048828  
PMID:24051492   PMID:24089055   PMID:24239982   PMID:24268780   PMID:24378737   PMID:24385426   PMID:24481314   PMID:24549704   PMID:24619734   PMID:24736997   PMID:25068868   PMID:25669688  
PMID:25936801   PMID:26051626   PMID:26271538   PMID:26776516   PMID:26901093   PMID:27365111   PMID:27717746   PMID:27771283   PMID:28423013   PMID:28985504   PMID:29085284   PMID:29165002  
PMID:29266826   PMID:29849897   PMID:30096135   PMID:31958455   PMID:32334629   PMID:33351992   PMID:33620678   PMID:34157911   PMID:35174626   PMID:36062789   PMID:36266079   PMID:36613816  


Genomics

Comparative Map Data
Bmal1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21167,331,756 - 167,430,235 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1167,331,633 - 167,430,231 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1175,666,810 - 175,765,622 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01182,852,900 - 182,951,712 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01175,548,108 - 175,646,871 (+)NCBIRnor_WKY
Rnor_6.01178,039,002 - 178,137,469 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1178,039,063 - 178,137,465 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01185,007,527 - 185,105,413 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41171,062,181 - 171,162,426 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11171,251,951 - 171,282,040 (+)NCBI
Celera1165,202,275 - 165,299,946 (+)NCBICelera
Cytogenetic Map1q33NCBI
BMAL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381113,276,652 - 13,387,266 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1113,276,652 - 13,387,266 (+)EnsemblGRCh38hg38GRCh38
GRCh371113,298,199 - 13,408,813 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361113,255,901 - 13,365,389 (+)NCBINCBI36Build 36hg18NCBI36
Build 341113,255,925 - 13,365,386NCBI
Celera1113,425,472 - 13,534,997 (+)NCBICelera
Cytogenetic Map11p15.3NCBI
HuRef1112,979,421 - 13,089,003 (+)NCBIHuRef
CHM1_11113,298,302 - 13,407,784 (+)NCBICHM1_1
T2T-CHM13v2.01113,369,378 - 13,480,010 (+)NCBIT2T-CHM13v2.0
Bmal1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397112,777,820 - 112,913,333 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7112,806,672 - 112,913,333 (+)EnsemblGRCm39 Ensembl
GRCm387113,178,471 - 113,314,126 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7113,207,465 - 113,314,126 (+)EnsemblGRCm38mm10GRCm38
MGSCv377120,350,979 - 120,457,636 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367112,998,646 - 113,105,303 (+)NCBIMGSCv36mm8
Celera7113,186,397 - 113,287,835 (+)NCBICelera
Cytogenetic Map7F1NCBI
cM Map759.17NCBI
Bmal1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541428,684,226 - 28,748,360 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541428,652,663 - 28,748,360 (+)NCBIChiLan1.0ChiLan1.0
BMAL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11113,163,028 - 13,240,376 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1113,163,028 - 13,240,376 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01113,436,580 - 13,547,135 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
ARNTL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12136,254,235 - 36,323,915 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2136,290,070 - 36,323,622 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2135,726,263 - 35,827,668 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02137,105,577 - 37,207,038 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2137,105,604 - 37,207,069 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12136,364,101 - 36,465,527 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02136,540,532 - 36,641,924 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02136,829,310 - 36,930,753 (+)NCBIUU_Cfam_GSD_1.0
Bmal1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494749,133,675 - 49,231,340 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365285,164,481 - 5,239,128 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049365285,167,611 - 5,239,128 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARNTL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl245,895,289 - 45,988,570 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1245,895,637 - 46,025,174 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2249,303,279 - 49,335,397 (-)NCBISscrofa10.2Sscrofa10.2susScr3
BMAL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1151,430,670 - 51,540,344 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl151,431,180 - 51,462,674 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038149,016,016 - 149,124,776 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bmal1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247665,317,635 - 5,391,645 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247665,295,120 - 5,391,645 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Bmal1
461 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1148
Count of miRNA genes:326
Interacting mature miRNAs:431
Transcripts:ENSRNOT00000019645, ENSRNOT00000046313
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
724521Uae1Urinary albumin excretion QTL 13.80.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)190508614173018436Rat
1358902Bw47Body weight QTL 471.67body mass (VT:0001259)body weight (CMO:0000012)190508614180359386Rat
1331793Bp200Blood pressure QTL 2003.71601arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194494440172949803Rat
1331751Bp199Blood pressure QTL 1993.60022arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)194494440181830018Rat
1331749Hrtrt11Heart rate QTL 112.973heart pumping trait (VT:2000009)heart rate (CMO:0000002)194494440198211706Rat
70209Niddm23Non-insulin dependent diabetes mellitus QTL 232.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)194494440198324465Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194642722214537671Rat
8655649Arrd1Age-related retinal degeneration QTL 14.89retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1100357752183970443Rat
1354591Cm36Cardiac mass QTL 364.1heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1102813953201278233Rat
1354615Cm32Cardiac mass QTL 325.2heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1102813953201278233Rat
1354606Bp246Blood pressure QTL 2463.6arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)1102813953218753816Rat
1300158Bp173Blood pressure QTL 1733.48arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)1115540693185145286Rat
7794788Mcs32Mammary carcinoma susceptibility QTL 322.61mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)1115540693238914717Rat
631199Cm23Cardiac mass QTL 234.60.0004heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1115585465172949803Rat
7421630Bp362Blood pressure QTL 3620.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118608292241799120Rat
631205Bp196Blood pressure QTL 19640.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118944897199050459Rat
631544Bp84Blood pressure QTL 845.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1123350408181759564Rat
1358189Cstrr1Cold stress response QTL 10.0001catecholamine amount (VT:0010543)urine norepinephrine level (CMO:0001629)1123350408182418476Rat
1641895Bp298Blood pressure QTL 298arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1123350408182418476Rat
1578770Stresp23Stress response QTL 23kidney sympathetic nerve activity (VT:0004050)stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio (CMO:0001786)1123350408182418476Rat
631549Bp89Blood pressure QTL 895.7arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1123350581201284552Rat
634348Bp138Blood pressure QTL 138arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1125611501168883176Rat
9685799Bp375Blood pressure QTL 375arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1125611501170611501Rat
631654Bp107Blood pressure QTL 107arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1125611501170611501Rat
9685802Bp376Blood pressure QTL 376arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1126540680171540680Rat
738006Anxrr14Anxiety related response QTL 1440.00035locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1130636910175636910Rat
738028Anxrr12Anxiety related response QTL 124.90.00001locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1130636910175636910Rat
6893347Bw98Body weight QTL 980.20.53body mass (VT:0001259)body weight (CMO:0000012)1133680936178680936Rat
6893361Bw104Body weight QTL 1040.590.27body mass (VT:0001259)body weight (CMO:0000012)1133680936178680936Rat
1558645Bw55Body weight QTL 553.20.004body mass (VT:0001259)body weight (CMO:0000012)1133680936178680936Rat
71118Thym1Thymus enlargement QTL 110.170.001thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)1136829932181829932Rat
724550Thym3Thymus enlargement QTL 37.820.001thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)1136829932181829932Rat
631519Pia11Pristane induced arthritis QTL 115.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1136830018181830018Rat
1598853Memor3Memory QTL 34.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)1143506580212458660Rat
61348Bp30Blood pressure QTL 302.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1144017057197814409Rat
70160Bw18Body weight QTL 185.7body mass (VT:0001259)body weight (CMO:0000012)1144267353196383635Rat
737828Hcas3Hepatocarcinoma susceptibility QTL 34.9liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)1144267353222987745Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1144267353251128347Rat
634315Niddm45Non-insulin dependent diabetes mellitus QTL 457.16blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1144267916172949660Rat
61379Bp44Blood pressure QTL 4419.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1144267916174133260Rat
7771612Cm80Cardiac mass QTL 808.4heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)1149448574221264292Rat
724531Uae5Urinary albumin excretion QTL 54urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)1150700142252085212Rat
1578759Uae30Urinary albumin excretion QTL 303.30.003urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1150700247252085048Rat
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1150700247252085048Rat
1354602Bw35Body weight QTL 3512.2body mass (VT:0001259)body weight (CMO:0000012)1151162512201278233Rat
1354620Kidm19Kidney mass QTL 194kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512201278233Rat
1354634Kidm12Kidney mass QTL 123.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)1151162512201278233Rat
1354636Lmblg1Limb length QTL 16.4tibia length (VT:0004357)tibia length (CMO:0000450)1151162512201278233Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512256448636Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
1358886Bp260Blood pressure QTL 2603.67arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1151162766225824951Rat
61343Bp28Blood pressure QTL 28arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1151646613196646613Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1153136852260522016Rat
2303622Vencon6Ventilatory control QTL 60.001respiration trait (VT:0001943)respiration rate (CMO:0000289)1154561505199561505Rat
1582204Livw1Liver weight QTL 13.60.0003liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)1155422851172949803Rat
4889428Stresp24Stress response QTL 240.05heart pumping trait (VT:2000009)absolute change in electrocardiographic low frequency R-R spectral component to high frequency R-R spectral component ratio (CMO:0002162)1155866514200866514Rat
631548Bp88Blood pressure QTL 8850.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1156677124176484451Rat
1354618Kidm15Kidney mass QTL 155kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)1156677124201278233Rat
2312420Pur17Proteinuria QTL 177.10.0001urine protein amount (VT:0005160)urine total protein excretion rate (CMO:0000756)1156677124218753816Rat
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1156677124256448636Rat
61347Bp197Blood pressure QTL 1974.2arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)1158633083203633083Rat
2292222Bp307Blood pressure QTL 3073.060.0014arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1164310393213533942Rat
2292220Bp306Blood pressure QTL 3063.470.00087arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1164310393243914901Rat
619613Bp77Blood pressure QTL 770.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1164747424209747424Rat
619613Bp77Blood pressure QTL 770.01arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1164747424209747424Rat
737974Bp161Blood pressure QTL 1610.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1164747558181133855Rat
2312558Glom17Glomerulus QTL 173.90.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)1166532971191278129Rat

Markers in Region
BM387564  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21167,382,554 - 167,382,704 (+)MAPPERmRatBN7.2
Rnor_6.01178,089,797 - 178,089,946NCBIRnor6.0
Rnor_5.01185,057,937 - 185,058,086UniSTSRnor5.0
RGSC_v3.41171,114,736 - 171,114,885UniSTSRGSC3.4
Celera1165,253,308 - 165,253,457UniSTS
RH 3.4 Map11318.5UniSTS
Cytogenetic Map1q34UniSTS
UniSTS:224416  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21167,367,349 - 167,367,440 (+)MAPPERmRatBN7.2
Rnor_6.01178,074,593 - 178,074,683NCBIRnor6.0
Rnor_5.01185,042,851 - 185,042,941UniSTSRnor5.0
RGSC_v3.41171,097,580 - 171,097,670UniSTSRGSC3.4
Celera1165,238,080 - 165,238,170UniSTS
Cytogenetic Map1q34UniSTS


Genetic Models
This gene Bmal1 is modified in the following models/strains

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 12 35 23 18 23 4 4 64 17 20 8 4
Low 1 31 22 18 1 18 4 7 10 18 21 3 4
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_024362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006230029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006230030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589068 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589070 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589071 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109748 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109755 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109778 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB012600 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC098214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF015953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF317669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC099833 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000043 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000046313   ⟹   ENSRNOP00000042830
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1167,331,820 - 167,430,231 (+)Ensembl
Rnor_6.0 Ensembl1178,039,063 - 178,137,465 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000095012   ⟹   ENSRNOP00000082167
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1167,331,633 - 167,430,231 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000097013   ⟹   ENSRNOP00000087129
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1167,331,633 - 167,430,231 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000114442   ⟹   ENSRNOP00000086597
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1167,399,854 - 167,430,231 (+)Ensembl
RefSeq Acc Id: NM_024362   ⟹   NP_077338
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21167,331,820 - 167,430,235 (+)NCBI
Rnor_6.01178,039,063 - 178,137,469 (+)NCBI
Rnor_5.01185,007,527 - 185,105,413 (+)NCBI
RGSC_v3.41171,062,181 - 171,162,426 (+)RGD
Celera1165,202,275 - 165,299,946 (+)RGD
Sequence:
RefSeq Acc Id: XM_006230029   ⟹   XP_006230091
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21167,331,759 - 167,430,235 (+)NCBI
Rnor_6.01178,039,004 - 178,137,469 (+)NCBI
Rnor_5.01185,007,527 - 185,105,413 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006230030   ⟹   XP_006230092
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21167,331,757 - 167,430,235 (+)NCBI
Rnor_6.01178,039,003 - 178,137,469 (+)NCBI
Rnor_5.01185,007,527 - 185,105,413 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017589065   ⟹   XP_017444554
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21167,331,757 - 167,430,235 (+)NCBI
Rnor_6.01178,039,003 - 178,137,469 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017589067   ⟹   XP_017444556
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21167,331,757 - 167,430,235 (+)NCBI
Rnor_6.01178,039,003 - 178,137,469 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017589068   ⟹   XP_017444557
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21167,331,756 - 167,430,235 (+)NCBI
Rnor_6.01178,039,002 - 178,137,469 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017589070   ⟹   XP_017444559
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21167,399,868 - 167,430,235 (+)NCBI
Rnor_6.01178,107,150 - 178,137,469 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039109748   ⟹   XP_038965676
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21167,331,757 - 167,430,235 (+)NCBI
RefSeq Acc Id: XM_039109755   ⟹   XP_038965683
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21167,331,757 - 167,430,235 (+)NCBI
RefSeq Acc Id: XM_039109763   ⟹   XP_038965691
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21167,393,148 - 167,430,235 (+)NCBI
RefSeq Acc Id: XM_039109778   ⟹   XP_038965706
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21167,400,612 - 167,430,235 (+)NCBI
RefSeq Acc Id: XM_039109788   ⟹   XP_038965716
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21167,399,866 - 167,430,235 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_077338   ⟸   NM_024362
- UniProtKB: Q9EPW1 (UniProtKB/Swiss-Prot),   D3ZT62 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006230091   ⟸   XM_006230029
- Peptide Label: isoform X3
- UniProtKB: Q9EPW1 (UniProtKB/Swiss-Prot),   D3ZT62 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006230092   ⟸   XM_006230030
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_017444557   ⟸   XM_017589068
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017444556   ⟸   XM_017589067
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZXD2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017444554   ⟸   XM_017589065
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZXD2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017444559   ⟸   XM_017589070
- Peptide Label: isoform X6
- UniProtKB: A0A8I6A2N7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000042830   ⟸   ENSRNOT00000046313
RefSeq Acc Id: XP_038965676   ⟸   XM_039109748
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZXD2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038965683   ⟸   XM_039109755
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZXD2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038965691   ⟸   XM_039109763
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZXD2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038965716   ⟸   XM_039109788
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038965706   ⟸   XM_039109778
- Peptide Label: isoform X5
RefSeq Acc Id: ENSRNOP00000082167   ⟸   ENSRNOT00000095012
RefSeq Acc Id: ENSRNOP00000086597   ⟸   ENSRNOT00000114442
RefSeq Acc Id: ENSRNOP00000087129   ⟸   ENSRNOT00000097013
Protein Domains
bHLH   PAC   PAS

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9EPW1-F1-model_v2 AlphaFold Q9EPW1 1-626 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13690323
Promoter ID:EPDNEW_R848
Type:initiation region
Name:Arntl_1
Description:aryl hydrocarbon receptor nuclear translocator-like
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01178,039,017 - 178,039,077EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:62003 AgrOrtholog
BioCyc Gene G2FUF-57769 BioCyc
Ensembl Genes ENSRNOG00000014448 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000042830 ENTREZGENE
  ENSRNOP00000042830.3 UniProtKB/TrEMBL
  ENSRNOP00000082167 ENTREZGENE
  ENSRNOP00000082167.1 UniProtKB/TrEMBL
  ENSRNOP00000086597.1 UniProtKB/TrEMBL
  ENSRNOP00000087129 ENTREZGENE
  ENSRNOP00000087129.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000046313 ENTREZGENE
  ENSRNOT00000046313.5 UniProtKB/TrEMBL
  ENSRNOT00000095012 ENTREZGENE
  ENSRNOT00000095012.1 UniProtKB/TrEMBL
  ENSRNOT00000097013 ENTREZGENE
  ENSRNOT00000097013.1 UniProtKB/TrEMBL
  ENSRNOT00000114442.1 UniProtKB/TrEMBL
Gene3D-CATH 4.10.280.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAS domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7936079 IMAGE-MGC_LOAD
InterPro bHLH_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HLH_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nuc_translocat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAS-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAS_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:29657 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:124556 IMAGE-MGC_LOAD
NCBI Gene 29657 ENTREZGENE
PANTHER ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR-LIKE PROTEIN 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam HLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAS_11 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Bmal1 PhenoGen
PRINTS NCTRNSLOCATR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE BHLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART HLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47459 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF55785 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGRFAMs sensory_box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZXD2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A2H7_RAT UniProtKB/TrEMBL
  A0A8I6A2N7 ENTREZGENE, UniProtKB/TrEMBL
  BMAL1_RAT UniProtKB/Swiss-Prot
  D3ZT62 ENTREZGENE, UniProtKB/TrEMBL
  Q9EPW1 ENTREZGENE
UniProt Secondary O88337 UniProtKB/Swiss-Prot
  O88810 UniProtKB/Swiss-Prot
  Q499M8 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-07-29 Bmal1  basic helix-loop-helix ARNT like 1  Arntl  aryl hydrocarbon receptor nuclear translocator-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Arntl  aryl hydrocarbon receptor nuclear translocator-like       Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression circadian rhythm of expression displayed in the suprachiasmatic nucleus (SCN), the site of the circadian clock, with the highest level at the subjective night 67927
gene_expression expressed in the olfactory bulb, hippocampus, and cerebellum 67927
gene_product member of the basic loop-helix-loop/PAS transcription factor family 61539
gene_product member of the basic loop-helix-loop/PAS transcription factor family 67927
gene_protein 626 amino acid 61539
gene_protein 626 amino acid 67927