Strain Report - Rat Genome Database

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Strain: F344-Kcna1Adms/Kyo

Symbol: F344-Kcna1Adms/Kyo
Strain: F344-Kcna1Adms
Substrain: Kyo
Full Name: ADMS (autosomal dominant myokymia and seizures) rat
RGD ID: 2314163
Citation ID: RRID:RGD_2314163
Ontology ID: RS:0001872
Alleles: Kcna1Adms
Also known as: F344-Ker/Kyo;NBRP Rat No: 0458; F344-Ker/Kyo; Kyoto Epileptic Rat; Boo; F344-Adms/Kyo; F344-Kcna1Adms/Kyo
Type: mutant
Source: National BioResource Project for the Rat in Japan
Origin: This strain was established by phenotype-driven ENU mutagenesis. A Kcna1 S309T mutation was identified in this model.
Coat Color: Albino
Last Known Status: Live Animals; Cryopreserved Sperm (as of 2017-05-04)
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24159,464,223 - 159,472,905RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.04159,190,781 - 159,192,526RGD_MAPPER_PIPELINERnor6.0
Rnor_5.04226,188,851 - 226,190,596RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.44163,011,777 - 163,013,522RGD_MAPPER_PIPELINERGSC3.4

Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype



Additional Information

RGD Curation Notes
Note Type Note Reference
null Startle response. Clonic convulsion.  
strain_reproduction Good breeding performance until seizure onset (about 4 or 5 months of age). Heterozygous females have less performance of nursing behavior for their pups. 1302502

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-05-04 F344-Kcna1Adms/Kyo  ADMS (autosomal dominant myokymia and seizures) rat  F344-Adms/Kyo  ADMS (autosomal dominant myokymia and seizures) rat  Symbol updated 68687 APPROVED
2012-05-18 F344-Adms/Kyo  ADMS (autosomal dominant myokymia and seizures) rat  F344-Ker/Kyo  KER(Kyoto Epileptic Rat), Boo  Symbol and/or name change 68913 APPROVED