Strain Report - Rat Genome Database

Send us a Message



 Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap)  (beta) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer) Overgo Probe Designer
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Strain Registration

Strain: iNP-Npyem6Sage-/-/Iusm

Symbol: iNP-Npyem6Sage-/-/Iusm
Strain: iNP-Npyem6Sage-/-
Substrain: Iusm
RGD ID: 11531106
Citation ID: RRID:RGD_11531106
Ontology ID: RS:0004216
Alleles: Npyem6Sage
Previously known as: Npy-/-; NP/Iusm-Npyem6Sage-/- ; NP/Iusm-Npyem6Sage-/-
Type: mutant
Source: Department of Gastroenterology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
Origin: The homozygous Npy mutant rats were produced by intercrossing the heterozygous ZFN mutants (iNP-Npyem6Sage+/- /Iusm) to produce homozygous and heterozygous offspring. Genotype of the homozygous offspring was confirmed by PCR amplification of a 26-bp deleted fragment, including 6 bp in intron 1 and 20 bp in exon 2.
Genetic Status: Homozygous
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2478,881,294 - 78,888,495RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0479,557,856 - 79,565,059RGD_MAPPER_PIPELINERnor6.0
Rnor_5.04144,233,753 - 144,240,956RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4478,038,013 - 78,045,187RGD_MAPPER_PIPELINERGSC3.4





Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

References

References - curated
# Reference Title Reference Citation
1. Npy deletion in an alcohol non-preferring rat model elicits differential effects on alcohol consumption and body weight. Qiu B, etal., J Genet Genomics. 2016 Jul 20;43(7):421-30. doi: 10.1016/j.jgg.2016.04.010. Epub 2016 Apr 29.

Region


Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-05-02 iNP-Npyem6Sage-/-/Iusm    NP/Iusm-Npyem6Sage-/-    Symbol and/or name change 68913 APPROVED
2018-03-14 NP/Iusm-Npyem6Sage-/-    NP/Iusm-Npyem6Sage-/-     Symbol updated 68687 APPROVED
2018-03-14 NP/Iusm-Npyem6Sage-/-    NP/Iusm-Npyem6Sage-/-     Symbol updated 68687 APPROVED
2016-08-26 NP/Iusm-Npyem6Sage-/-     NP/Iusm-Npyem6Sage-/-     Name updated 68913 APPROVED
2016-08-26 NP/Iusm-Npyem6Sage-/-     NP/Iusm-Npyem6Sage-/-     Name updated 68913 APPROVED
2016-08-26 NP/Iusm-Npyem6Sage-/-     NP/Iusm-Npyem6Sage-/-     Name updated 68913 APPROVED
2016-08-26 NP/Iusm-Npyem6Sage-/-     NP/Iusm-Npyem6Sage-/-     Name updated 68913 APPROVED
2016-08-26 NP/Iusm-Npyem6Sage-/-     NP/Iusm-Npyem6Sage-/-     Name updated 68913 APPROVED
2016-08-26 NP/Iusm-Npyem6Sage-/-     NP/Iusm-Npyem6Sage-/-     Name updated 68913 APPROVED