Vnn1 (vanin 1) - Rat Genome Database

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Gene: Vnn1 (vanin 1) Rattus norvegicus
Analyze
Symbol: Vnn1
Name: vanin 1
RGD ID: 1310075
Description: Predicted to enable pantetheine hydrolase activity. Predicted to be involved in several processes, including coenzyme A catabolic process; positive regulation of T cell differentiation in thymus; and positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway. Predicted to be located in plasma membrane and side of membrane. Orthologous to human VNN1 (vanin 1); PARTICIPATES IN pantothenic acid metabolic pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: MGC114385; pantetheinase; Tiff66
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: Vnn1em2Mcwi   Vnn1em1Mcwi  
Genetic Models: SS-Vnn1em1Mcwi SS-Vnn1em2Mcwi
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8123,356,324 - 23,366,629 (-)NCBIGRCr8
mRatBN7.2121,537,084 - 21,547,395 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl121,537,094 - 21,547,395 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx121,316,351 - 21,326,676 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0127,316,396 - 27,326,721 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0121,513,723 - 21,524,007 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0122,614,832 - 22,625,134 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl122,614,783 - 22,625,204 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0124,089,365 - 24,099,667 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4122,087,290 - 22,097,592 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1122,090,508 - 22,100,537 (-)NCBI
Celera120,280,201 - 20,290,503 (-)NCBICelera
Cytogenetic Map1p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-amino-2-deoxy-D-glucopyranose  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aldehydo-D-glucosamine  (ISO)
allyl alcohol  (ISO)
alpha-Zearalanol  (EXP)
amiodarone  (EXP,ISO)
amphotericin B  (ISO)
arsenous acid  (ISO)
azathioprine  (ISO)
benzbromarone  (EXP)
benzo[a]pyrene  (ISO)
beta-D-glucosamine  (ISO)
beta-naphthoflavone  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bosentan  (ISO)
buspirone  (EXP)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
chlordecone  (ISO)
chloroform  (ISO)
chlorpyrifos  (EXP,ISO)
choline  (ISO)
ciglitazone  (ISO)
cisplatin  (ISO)
Citreoviridin  (ISO)
clofibrate  (EXP,ISO)
Clofop  (ISO)
cobalt dichloride  (EXP)
copper(II) sulfate  (ISO)
corn oil  (EXP)
cyanocob(III)alamin  (ISO)
cyclosporin A  (ISO)
cysteamine  (ISO)
dapagliflozin  (EXP)
decabromodiphenyl ether  (EXP)
diarsenic trioxide  (ISO)
dibenzofurans  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
dichloroacetic acid  (ISO)
dicrotophos  (ISO)
diethylstilbestrol  (ISO)
dimethylarsinic acid  (ISO)
diquat  (ISO)
diuron  (EXP)
endosulfan  (EXP)
epoxiconazole  (ISO)
ethylene glycol  (EXP,ISO)
fenofibrate  (EXP,ISO)
finasteride  (EXP)
fipronil  (EXP)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
fructose  (EXP)
gemfibrozil  (EXP)
gentamycin  (EXP)
glafenine  (EXP)
glutathione  (ISO)
glycine betaine  (ISO)
GW 4064  (ISO)
hydrogen peroxide  (ISO)
indole-3-methanol  (EXP)
inulin  (ISO)
L-ethionine  (EXP)
L-methionine  (ISO)
leflunomide  (EXP,ISO)
metformin  (EXP)
methapyrilene  (EXP)
methotrexate  (ISO)
methylarsonic acid  (ISO)
Muraglitazar  (EXP)
N-acetyl-L-cysteine  (EXP)
N-nitrosodiethylamine  (EXP,ISO)
nefazodone  (EXP)
nimesulide  (EXP)
nitrofen  (EXP)
ochratoxin A  (EXP)
oleic acid  (ISO)
omeprazole  (EXP)
orphenadrine  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
pentachlorophenol  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
permethrin  (ISO)
phenformin  (EXP)
phenobarbital  (ISO)
phenol  (ISO)
piperonyl butoxide  (EXP)
pirinixic acid  (EXP,ISO)
pravastatin  (ISO)
progesterone  (ISO)
propanal  (ISO)
quercetin  (ISO)
reactive oxygen species  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
spirotetramat  (ISO)
streptozocin  (EXP)
Tesaglitazar  (EXP)
tetrachloroethene  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (EXP,ISO)
triphenyl phosphate  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
troglitazone  (EXP,ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
zaragozic acid A  (EXP,ISO)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Comprehensive gene review and curation RGD comprehensive gene curation
12. PSMD11, PTPRM and PTPRB as novel biomarkers of pancreatic cancer progression. Sahni S, etal., Biochim Biophys Acta Gen Subj. 2020 Nov;1864(11):129682. doi: 10.1016/j.bbagen.2020.129682. Epub 2020 Jul 12.
Additional References at PubMed
PMID:8934567   PMID:11491533   PMID:12477932   PMID:14966568   PMID:15282320   PMID:21544065   PMID:22399813   PMID:23376485   PMID:24106341   PMID:25478849   PMID:26932716   PMID:27014792  
PMID:30332759   PMID:31514290   PMID:34768879   PMID:35352799  


Genomics

Comparative Map Data
Vnn1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8123,356,324 - 23,366,629 (-)NCBIGRCr8
mRatBN7.2121,537,084 - 21,547,395 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl121,537,094 - 21,547,395 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx121,316,351 - 21,326,676 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0127,316,396 - 27,326,721 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0121,513,723 - 21,524,007 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0122,614,832 - 22,625,134 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl122,614,783 - 22,625,204 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0124,089,365 - 24,099,667 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4122,087,290 - 22,097,592 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1122,090,508 - 22,100,537 (-)NCBI
Celera120,280,201 - 20,290,503 (-)NCBICelera
Cytogenetic Map1p12NCBI
VNN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386132,680,849 - 132,714,055 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6132,680,849 - 132,714,055 (-)EnsemblGRCh38hg38GRCh38
GRCh376133,001,988 - 133,035,194 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366133,044,422 - 133,076,881 (-)NCBINCBI36Build 36hg18NCBI36
Build 346133,044,422 - 133,076,881NCBI
Celera6133,748,822 - 133,782,014 (-)NCBICelera
Cytogenetic Map6q23.2NCBI
HuRef6130,576,916 - 130,610,106 (-)NCBIHuRef
CHM1_16133,265,672 - 133,298,869 (-)NCBICHM1_1
T2T-CHM13v2.06133,875,818 - 133,909,022 (-)NCBIT2T-CHM13v2.0
Vnn1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391023,770,586 - 23,781,242 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1023,770,586 - 23,781,241 (+)EnsemblGRCm39 Ensembl
GRCm381023,894,688 - 23,905,344 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1023,894,688 - 23,905,343 (+)EnsemblGRCm38mm10GRCm38
MGSCv371023,614,494 - 23,625,149 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361023,573,041 - 23,594,755 (+)NCBIMGSCv36mm8
Celera1024,828,202 - 24,838,840 (+)NCBICelera
Cytogenetic Map10A4NCBI
cM Map1011.33NCBI
Vnn1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543613,238,603 - 13,259,577 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543613,238,307 - 13,266,800 (-)NCBIChiLan1.0ChiLan1.0
VNN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25152,665,525 - 152,697,484 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16150,572,617 - 150,604,502 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06130,459,268 - 130,491,167 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16134,566,110 - 134,598,784 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6134,566,117 - 134,598,784 (-)Ensemblpanpan1.1panPan2
VNN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1125,678,039 - 25,704,579 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl125,678,042 - 25,696,807 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha126,742,992 - 26,770,993 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0125,767,887 - 25,802,756 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl125,767,890 - 25,796,358 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1125,690,559 - 25,711,049 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0125,596,017 - 25,624,588 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0125,852,617 - 25,901,434 (-)NCBIUU_Cfam_GSD_1.0
Vnn1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946120,920,545 - 120,951,976 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936560701,892 - 729,526 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936560701,857 - 729,516 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
VNN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl131,000,255 - 31,024,505 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1131,003,338 - 31,023,731 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2134,520,052 - 34,544,689 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Vnn1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247536,867,953 - 6,892,186 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247536,869,269 - 6,892,217 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Vnn1
75 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:402
Count of miRNA genes:231
Interacting mature miRNAs:266
Transcripts:ENSRNOT00000021694
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
1578650Bmd6Bone mineral density QTL 612.2femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)150910843284926Rat
1354647Despr8Despair related QTL 80.0000341locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1124744506Rat
1578651Bmd7Bone mineral density QTL 714.2femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)150910843284926Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)11148131282174945Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)150910886060548Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
7421626Bp360Blood pressure QTL 3600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1439328949393289Rat
2313070Bss52Bone structure and strength QTL 524.40.0001body length (VT:0001256)body length (CMO:0000013)1132356093Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
631494Bp95Blood pressure QTL 95400.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)11620621049268520Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)11148131282174945Rat
5684998Bss101Bone structure and strength QTL 1013.6tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)11543162149361612Rat
2298546Neuinf4Neuroinflammation QTL 45.1nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)1128736750Rat
5684999Bss102Bone structure and strength QTL 1025.57e-07tibia strength trait (VT:1000284)tibia stiffness (CMO:0001735)11543162149361612Rat
1300167Hrtrt2Heart rate QTL 24.35heart pumping trait (VT:2000009)heart rate (CMO:0000002)11148131275088344Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)11148131282174945Rat
2317755Glom22Glomerulus QTL 223.8urine protein amount (VT:0005160)urine protein level (CMO:0000591)11148148232355910Rat
1578756Iddm22Insulin dependent diabetes mellitus QTL 222.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)11183518156835181Rat
631508Sald1Serum aldosterone level QTL 13.7blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)1985600154856001Rat
2313090Bmd69Bone mineral density QTL 694.40.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)1132356093Rat
4889451Eae29Experimental allergic encephalomyelitis QTL 295.51nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1592587724697545Rat
724520Bp145Blood pressure QTL 1452.10.0024arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12078482865784828Rat
1558642Prcr2Prostate cancer resistance QTL 24.3prostate integrity trait (VT:0010571)area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)12076315844095856Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)11148131282174945Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
738020Pia8Pristane induced arthritis QTL 84.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1165833076Rat
1600360Mcs16Mammary carcinoma susceptibility QTL 162.4mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1224439043433040Rat
1578669Bss9Bone structure and strength QTL 96.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)150910843284926Rat
2302038Pia31Pristane induced arthritis QTL 315.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)11099206555992065Rat
634353Rends2Renal damage susceptibility QTL 20.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)11933357156983283Rat
2313053Bss51Bone structure and strength QTL 513.80.0001tibia length (VT:0004357)tibia length (CMO:0000450)1132356093Rat

Markers in Region
Vnn1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2121,543,810 - 21,543,926 (+)MAPPERmRatBN7.2
Rnor_6.0122,621,550 - 22,621,665NCBIRnor6.0
Rnor_5.0124,096,083 - 24,096,198UniSTSRnor5.0
RGSC_v3.4122,094,008 - 22,094,123UniSTSRGSC3.4
Celera120,286,919 - 20,287,034UniSTS
Cytogenetic Map1p12UniSTS
RH131037  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2121,537,626 - 21,537,844 (+)MAPPERmRatBN7.2
Rnor_6.0122,615,368 - 22,615,585NCBIRnor6.0
Rnor_5.0124,089,901 - 24,090,118UniSTSRnor5.0
RGSC_v3.4122,087,826 - 22,088,043UniSTSRGSC3.4
Celera120,280,737 - 20,280,954UniSTS
RH 3.4 Map1217.1UniSTS
Cytogenetic Map1p12UniSTS


Genetic Models
This gene Vnn1 is modified in the following models/strains:
SS-Vnn1em1Mcwi     SS-Vnn1em2Mcwi    


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000021694   ⟹   ENSRNOP00000021694
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl121,537,094 - 21,547,395 (-)Ensembl
Rnor_6.0 Ensembl122,614,783 - 22,625,204 (-)Ensembl
RefSeq Acc Id: NM_001025623   ⟹   NP_001020794
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8123,356,327 - 23,366,629 (-)NCBI
mRatBN7.2121,537,091 - 21,547,395 (-)NCBI
Rnor_6.0122,614,832 - 22,625,134 (-)NCBI
Rnor_5.0124,089,365 - 24,099,667 (-)NCBI
RGSC_v3.4122,087,290 - 22,097,592 (-)RGD
Celera120,280,201 - 20,290,503 (-)RGD
Sequence:
RefSeq Acc Id: XM_039103008   ⟹   XP_038958936
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8123,356,324 - 23,364,217 (-)NCBI
mRatBN7.2121,537,084 - 21,544,983 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001020794 (Get FASTA)   NCBI Sequence Viewer  
  XP_038958936 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH98934 (Get FASTA)   NCBI Sequence Viewer  
  EDL87746 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000021694.4
RefSeq Acc Id: NP_001020794   ⟸   NM_001025623
- Peptide Label: precursor
- UniProtKB: Q4KLZ0 (UniProtKB/TrEMBL),   F7FPD6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000021694   ⟸   ENSRNOT00000021694
RefSeq Acc Id: XP_038958936   ⟸   XM_039103008
- Peptide Label: isoform X1
Protein Domains
CN hydrolase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q4KLZ0-F1-model_v2 AlphaFold Q4KLZ0 1-512 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689531
Promoter ID:EPDNEW_R55
Type:multiple initiation site
Name:Vnn1_1
Description:vanin 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0122,625,023 - 22,625,083EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310075 AgrOrtholog
BioCyc Gene G2FUF-62078 BioCyc
Ensembl Genes ENSRNOG00000016219 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000021694.7 UniProtKB/TrEMBL
Gene3D-CATH 3.60.110.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7441890 IMAGE-MGC_LOAD
InterPro Biotinidase/VNN UniProtKB/TrEMBL
  Biotinidase_euk UniProtKB/TrEMBL
  C-N_Hydrolase_sf UniProtKB/TrEMBL
  Ntlse/CNhydtse UniProtKB/TrEMBL
  Vanin_C UniProtKB/TrEMBL
KEGG Report rno:29142 UniProtKB/TrEMBL
MGC_CLONE MGC:114385 IMAGE-MGC_LOAD
NCBI Gene 29142 ENTREZGENE
PANTHER PANTETHEINASE UniProtKB/TrEMBL
  PTHR10609 UniProtKB/TrEMBL
Pfam CN_hydrolase UniProtKB/TrEMBL
  Vanin_C UniProtKB/TrEMBL
PhenoGen Vnn1 PhenoGen
PIRSF Biotinidase UniProtKB/TrEMBL
PROSITE CN_HYDROLASE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000016219 RatGTEx
Superfamily-SCOP Ntlse/CNhydtse UniProtKB/TrEMBL
UniProt F7FPD6 ENTREZGENE, UniProtKB/TrEMBL
  Q4KLZ0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Vnn1  vanin 1  Vnn1_predicted  vanin 1 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Vnn1_predicted  vanin 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED