Gene: Fmr1 (fragile X mental retardation 1) Rattus norvegicus
Symbol: Fmr1
Name: fragile X mental retardation 1
Description: ENCODES a protein that exhibits mRNA binding; protein domain specific binding; protein kinase binding; INVOLVED IN cellular response to monosodium glutamate; cellular response to potassium ion; detection of mechanical stimulus involved in sensory perception; ASSOCIATED WITH abnormal response to social novelty; abnormal social play behavior; enlarged testis; ASSOCIATED WITH Autism Spectrum Disorder; Brain Injuries; Epileptic Encephalopathy, Childhood-Onset; FOUND IN axon; axon terminus; axonal growth cone; INTERACTS WITH (S)-3,5-dihydroxyphenylglycine; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene
Type: protein-coding
Also known as: FMRP; fragile X mental retardation protein 1 homolog; fragile X mental retardation syndrome 1 homolog; fragile X mental retardation-1 protein; protein FMR-1; ragile X mental retardation protein; synaptic functional regulator FMR1
Homo sapiens (human) : FMR1 (fragile X mental retardation 1)  HGNC  AGR
Mus musculus (house mouse) : Fmr1 (fragile X mental retardation syndrome 1)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Fmr1 (fragile X mental retardation 1)
Pan paniscus (bonobo/pygmy chimpanzee) : FMR1 (fragile X mental retardation 1)
Canis lupus familiaris (dog) : FMR1 (fragile X mental retardation 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fmr1 (fragile X mental retardation 1)
more info ...
Allele / Splice: Fmr1em2Mcwi   Fmr1em4Mcwi   Fmr1em1Sage  
Genetic Models: SD-Fmr1em1Sage LE-Fmr1em2Mcwi LE-Fmr1em4Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0X154,684,924 - 154,722,369 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01150,408,220 - 150,445,658 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X154,756,031 - 154,793,782 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X154,829,463 - 154,867,215 (+)NCBI
Celera1134,092,390 - 134,130,141 (-)NCBICelera
Cytogenetic MapXq37NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Fmr1
AGR Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2623
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-11-07
Status: ACTIVE