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Strain: F344-Il2rgem7Kyo

Symbol: F344-Il2rgem7Kyo
Strain: F344-Il2rgem7
Substrain: Kyo
RGD ID: 8552331
Citation ID: RRID:RGD_8552331
Ontology ID: RS:0003743
Alleles: Il2rgem7Kyo
Previously known as: XSCID-TALEN; NBRP Rat No: 0694; F344-Il2rgem7Kyo
Type: mutant
Source: National BioResource Project for the Rat in Japan
Origin: The strain having a Endonuclease-induced 7 bp deletion mutation in the 2nd exon of the rat Il2rg gene was established by TAL effector nuclease obtained from Dr. Yamamoto at Hiroshima University.
Coat Color: albino
Inbred Generations: G1
Last Known Status: Unknown
Research Usage Hematology; Immunology
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X66,395,330 - 66,399,026RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0X71,165,378 - 71,169,078RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0X72,017,856 - 72,021,516RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4X89,342,055 - 89,345,715RGD_MAPPER_PIPELINERGSC3.4


References - curated
# Reference Title Reference Citation
1. Strains registered by the National Bio Resource Project for the Rat in Japan Personal Communication with NBRP
2. RGD Strain RSO annotation pipeline RGD Automated Pipelines


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics This strain shows severe combined immunodeficiency caused by a 7-bp deletion in the exon 2 of Il2rg gene. 1302502

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-05-02 F344-Il2rgem7Kyo    F344-Il2rgem7Kyo    Name updated 68913 APPROVED
2014-05-02 F344-Il2rgem7Kyo    F344-Il2rgem7Kyo    Name updated 68913 APPROVED