Gene: Frem2 (Fras1 related extracellular matrix protein 2) Rattus norvegicus
Analyze
Symbol: Frem2
Name: Fras1 related extracellular matrix protein 2
Description: INVOLVED IN embryonic digit morphogenesis (ortholog); eye development (ortholog); heart development (ortholog); ASSOCIATED WITH abnormal eyelid fusion; fused right lung lobes; syndactyly; ASSOCIATED WITH Fraser Syndrome 2; Childhood Schizophrenia (ortholog); congenital diaphragmatic hernia (ortholog); FOUND IN basement membrane (ortholog); INTERACTS WITH 3-chloropropane-1,2-diol; acrylamide; bis(2-chloroethyl) sulfide
AGR Description: Predicted to be involved in animal organ development, embryonic digit morphogenesis, and morphogenesis of an epithelium; predicted to localize to the basement membrane; orthologous to human FREM2 (FRAS1 related extracellular matrix protein 2).
Merged Description: Predicted to be involved in animal organ development, embryonic digit morphogenesis, and morphogenesis of an epithelium; predicted to localize to the basement membrane; orthologous to human FREM2 (FRAS1 related extracellular matrix protein 2); INTERACTS WITH 3-chloropropane-1,2-diol; acrylamide; bis(2-chloroethyl) sulfide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: FRAS1-related extracellular matrix protein 2; LOC310418; RGD1566012; similar to OTTHUMP00000018288
Orthologs:
Homo sapiens (human) : FREM2 (FRAS1 related extracellular matrix protein 2)  HGNC  Alliance
Mus musculus (house mouse) : Frem2 (Fras1 related extracellular matrix protein 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Frem2 (FRAS1 related extracellular matrix protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : FREM2 (FRAS1 related extracellular matrix protein 2)
Canis lupus familiaris (dog) : FREM2 (FRAS1 related extracellular matrix protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Frem2 (FRAS1 related extracellular matrix protein 2)
Sus scrofa (pig) : FREM2 (FRAS1 related extracellular matrix protein 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02142,747,501 - 142,885,604 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02162,430,795 - 162,568,910 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42142,464,169 - 142,604,059 (-)NCBIRGSC3.4rn4RGSC3.4
Celera2132,100,362 - 132,238,927 (-)NCBICelera
Cytogenetic Map2q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Frem2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1566012
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.