(20S)-ginsenoside Rg3 multiple interactions ISO Slc6a3 (Mus musculus) 6480464 [Plant Extracts co-treated with Terpenes co-treated with ginsenoside Rg3] inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of SLC6A3 protein] CTD PMID:24394491 (R)-noradrenaline multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 SLC6A3 protein promotes the reaction [Norepinephrine results in increased activity of TAAR1 protein] CTD PMID:17234900 (R)-noradrenaline increases uptake ISO SLC6A3 (Homo sapiens) 6480464 SLC6A3 protein results in increased uptake of Norepinephrine CTD PMID:17250655 (R)-octopamine multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 indatraline inhibits the reaction [SLC6A3 protein promotes the reaction [Octopamine results in increased activity of TAAR1 protein]] more ... CTD PMID:17234900 (S)-amphetamine increases activity ISO Slc6a3 (Mus musculus) 6480464 Dextroamphetamine results in increased activity of SLC6A3 protein CTD PMID:12716422 (S)-amphetamine multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 Dextroamphetamine inhibits the reaction [SLC6A3 protein results in increased uptake of Dopamine] CTD PMID:30776375 (S)-amphetamine multiple interactions EXP 6480464 Dextroamphetamine inhibits the reaction [SLC6A3 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:24841869 (S)-amphetamine decreases activity ISO SLC6A3 (Homo sapiens) 6480464 Dextroamphetamine results in decreased activity of SLC6A3 protein CTD PMID:30776375 (S)-amphetamine decreases expression EXP 6480464 Dextroamphetamine results in decreased expression of SLC6A3 protein CTD PMID:15900317 (S)-amphetamine multiple interactions ISO Slc6a3 (Mus musculus) 6480464 1-(2 (diphenylmethoxy)ethyl)-4-(3-phenylpropyl)piperazine inhibits the reaction [Dextroamphetamine results in increased activity of SLC6A3 protein] CTD PMID:12716422 (S)-amphetamine affects response to substance ISO Slc6a3 (Mus musculus) 6480464 SLC6A3 protein affects the susceptibility to Dextroamphetamine CTD PMID:11797063 (S)-naringenin decreases expression EXP 6480464 naringenin results in decreased expression of SLC6A3 mRNA CTD PMID:34655599 (S)-naringenin multiple interactions EXP 6480464 naringenin inhibits the reaction [Paraquat results in decreased expression of SLC6A3 mRNA] CTD PMID:34655599 (S)-nicotine multiple interactions EXP 6480464 Dihydro-beta-Erythroidine affects the reaction [Nicotine results in decreased activity of SLC6A3 protein] and Mecamylamine affects the reaction [Nicotine results in decreased activity of SLC6A3 protein] CTD PMID:23999947 (S)-nicotine increases methylation ISO Slc6a3 (Mus musculus) 6480464 Nicotine results in increased methylation of SLC6A3 promoter CTD PMID:31945395 (S)-nicotine decreases expression ISO Slc6a3 (Mus musculus) 6480464 Nicotine results in decreased expression of SLC6A3 mRNA and Nicotine results in decreased expression of SLC6A3 protein CTD PMID:31945395 (S)-nicotine multiple interactions ISO Slc6a3 (Mus musculus) 6480464 Nicotine inhibits the reaction [Paraquat results in decreased expression of SLC6A3 protein] CTD PMID:17227438 (S)-nicotine decreases activity EXP 6480464 Nicotine results in decreased activity of SLC6A3 protein CTD PMID:23999947 1,2-dimethylhydrazine decreases expression ISO Slc6a3 (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in decreased expression of SLC6A3 mRNA CTD PMID:22206623 1-(2-(diphenylmethoxy)ethyl)-4-(2-(4-azido-3-iodophenyl)ethyl)piperazine affects binding EXP 1625661 1-(2-(diphenylmethoxy)ethyl)-4-(2-(4-azido-3-iodophenyl)ethyl)piperazine binds to Slc6a3 protein RGD 1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine affects binding ISO Slc6a3 (Mus musculus) 6480464 1-(2 (diphenylmethoxy)ethyl)-4-(3-phenylpropyl)piperazine binds to SLC6A3 protein CTD PMID:11226678 1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine affects binding EXP 6480464 1-(2 (diphenylmethoxy)ethyl)-4-(3-phenylpropyl)piperazine binds to SLC6A3 protein CTD PMID:15985715 more ... 1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine multiple interactions EXP 6480464 Paraquat inhibits the reaction [1-(2 (diphenylmethoxy)ethyl)-4-(3-phenylpropyl)piperazine binds to SLC6A3 protein] CTD PMID:15985715 more ... 1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine multiple interactions ISO Slc6a3 (Mus musculus) 6480464 1-(2 (diphenylmethoxy)ethyl)-4-(3-phenylpropyl)piperazine inhibits the reaction [Dextroamphetamine results in increased activity of SLC6A3 protein] and NR3C1 protein inhibits the reaction [1-(2 (diphenylmethoxy)ethyl)-4-(3-phenylpropyl)piperazine binds to SLC6A3 protein] CTD PMID:11226678 and PMID:12716422 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile multiple interactions ISO Slc6a3 (Mus musculus) 6480464 SLC6A3 mutant form promotes the reaction [Citalopram results in increased abundance of Dopamine] CTD PMID:14691264 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile affects response to substance ISO SLC6A3 (Homo sapiens) 6480464 SLC6A3 protein polymorphism affects the susceptibility to Citalopram CTD PMID:31009648 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 [SLC6A3 protein polymorphism affects the susceptibility to Citalopram] which affects the uptake of Dopamine and Citalopram inhibits the reaction [SLC6A3 protein results in increased uptake of Dopamine] CTD PMID:31009648 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine decreases expression ISO Slc6a3 (Mus musculus) 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:15329391 more ... 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine increases expression ISO Slc6a3 (Mus musculus) 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:30195017 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine decreases activity ISO Slc6a3 (Mus musculus) 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:16011487 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactions ISO Slc6a3 (Mus musculus) 6480464 1 more ... CTD PMID:16011487 more ... 17beta-estradiol multiple interactions EXP 6480464 [bisphenol A co-treated with Estradiol] inhibits the reaction [SLC6A3 protein affects the export of Dopamine] more ... CTD PMID:16451217 and PMID:19479021 17beta-estradiol multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 [Estradiol binds to ESR2 protein] which results in increased expression of SLC6A3 mRNA CTD PMID:20404318 17beta-estradiol multiple interactions ISO Slc6a3 (Mus musculus) 6480464 Estradiol inhibits the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:16011487 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of SLC6A3 protein CTD PMID:16451217 17beta-estradiol 3-benzoate multiple interactions ISO Slc6a3 (Mus musculus) 6480464 estradiol 3-benzoate inhibits the reaction [Methamphetamine results in decreased expression of SLC6A3 mRNA] and estradiol 3-benzoate inhibits the reaction [Methamphetamine results in decreased expression of SLC6A3 protein] CTD PMID:15249736 2,2',4,4',5,5'-hexachlorobiphenyl decreases expression EXP 6480464 2 more ... CTD PMID:26215117 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of SLC6A3 mRNA CTD PMID:32109520 2,5-dimethoxy-4-bromophenethylamine multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 2-(4-bromo-2 more ... CTD PMID:28506818 2-aminopropiophenone decreases expression ISO Slc6a3 (Mus musculus) 6480464 cathinone analog results in decreased expression of SLC6A3 mRNA CTD PMID:28173643 2-phenylethylamine multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 Cocaine inhibits the reaction [SLC6A3 protein results in increased transport of phenethylamine] and SLC6A3 protein promotes the reaction [phenethylamine results in increased activity of TAAR1 protein] CTD PMID:15764732 and PMID:17234900 2-phenylethylamine increases transport ISO SLC6A3 (Homo sapiens) 6480464 SLC6A3 protein results in increased transport of phenethylamine CTD PMID:15764732 3,4-methylenedioxymethamphetamine multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 N-Methyl-3 more ... CTD PMID:28506818 more ... 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 bisindolylmaleimide I inhibits the reaction [[Dopamine co-treated with SLC6A3 protein] results in increased expression of FOS protein] CTD PMID:12112414 4,4'-sulfonyldiphenol increases expression ISO Slc6a3 (Mus musculus) 6480464 bisphenol S results in increased expression of SLC6A3 mRNA CTD PMID:30951980 4,4'-sulfonyldiphenol decreases methylation ISO SLC6A3 (Homo sapiens) 6480464 bisphenol S results in decreased methylation of SLC6A3 gene CTD PMID:31601247 4-[2-(diphenylmethoxy)ethyl]-1-[(4-azidophenyl)-methyl]-piperidine affects binding EXP 1625661 4-[2-(diphenylmethoxy)ethyl]-1-[(4-azidophenyl)-methyl]-piperidine binds to Slc6a3 protein RGD 4-nitrotoluene decreases expression EXP 6480464 4-nitrotoluene results in decreased expression of SLC6A3 mRNA CTD PMID:15265578 7-NITROINDAZOLE multiple interactions ISO Slc6a3 (Mus musculus) 6480464 7-nitroindazole inhibits the reaction [Methamphetamine results in decreased expression of SLC6A3 protein] CTD PMID:20575850 acrylamide decreases expression EXP 6480464 Acrylamide results in decreased expression of SLC6A3 and Acrylamide results in decreased expression of SLC6A3 mRNA CTD PMID:25943760 and PMID:28959563 albiflorin affects expression EXP 6480464 albiflorin affects the expression of SLC6A3 CTD PMID:26475043 alcohol increases activity ISO Slc6a3 (Mus musculus) 6480464 Alcohols results in increased activity of SLC6A3 protein CTD PMID:11165777 alcohol multiple interactions ISO Slc6a3 (Mus musculus) 6480464 [Alcohols co-treated with Cocaine] results in increased activity of SLC6A3 protein more ... CTD PMID:11165777 all-trans-retinoic acid multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 [Tretinoin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SLC6A3 protein CTD PMID:24101030 alpha,alpha-trehalose multiple interactions ISO Slc6a3 (Mus musculus) 6480464 Trehalose inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1 more ... CTD PMID:25064079 AM-251 multiple interactions EXP 6480464 AM 251 affects the reaction [(3R)-((2 more ... CTD PMID:29113897 aminorex multiple interactions EXP 6480464 Aminorex inhibits the reaction [SLC6A3 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:24841869 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of SLC6A3 mRNA CTD PMID:16483693 amphetamine multiple interactions ISO Slc6a3 (Mus musculus) 6480464 SLC6A3 protein affects the reaction [Amphetamine results in increased expression of FOS protein] CTD PMID:12699766 amphetamine increases response to substance ISO SLC6A3 (Homo sapiens) 6480464 SLC6A3 protein results in increased susceptibility to Amphetamine CTD PMID:15602501 amphetamine affects response to substance ISO SLC6A3 (Homo sapiens) 6480464 SLC6A3 3' UTR polymorphism affects the susceptibility to Amphetamine CTD PMID:19462300 amphetamine decreases expression EXP 6480464 Amphetamine results in decreased expression of DAT mRNA CTD PMID:15183010 amphetamine increases expression EXP 6480464 Amphetamine results in increased expression of SLC6A3 mRNA CTD PMID:16126238 amphetamine decreases expression ISO Slc6a3 (Mus musculus) 6480464 Amphetamine results in decreased expression of SLC6A3 protein CTD PMID:11731100 amphetamine decreases response to substance ISO SLC6A3 (Homo sapiens) 6480464 SLC6A3 3' UTR polymorphism results in decreased susceptibility to Amphetamine CTD PMID:15602501 amphetamine affects localization ISO SLC6A3 (Homo sapiens) 6480464 Amphetamine affects the localization of SLC6A3 protein CTD PMID:16684900 amphetamine multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 [Amphetamine co-treated with SLC6A3 protein] results in increased expression of FOS mRNA more ... CTD PMID:11731100 more ... Aroclor 1254 multiple interactions ISO Slc6a3 (Mus musculus) 6480464 [Chlorodiphenyl (54% Chlorine) co-treated with aroclor 1260] inhibits the reaction [SLC6A3 protein results in increased uptake of Dopamine] more ... CTD PMID:16702228 and PMID:24394491 Aroclor 1254 decreases expression ISO Slc6a3 (Mus musculus) 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of SLC6A3 protein CTD PMID:22094459 and PMID:24394491 Aroclor 1254 multiple interactions EXP 6480464 [aroclor 1242 co-treated with aroclor 1248 co-treated with Chlorodiphenyl (54% Chlorine) co-treated with aroclor 1260] results in decreased expression of SLC6A3 protein and [Chlorodiphenyl (54% Chlorine) co-treated with aroclor 1242 co-treated with aroclor 1248] results in decreased expression of SLC6A3 mRNA CTD PMID:17324953 and PMID:29879404 arsenite(3-) decreases expression ISO Slc6a3 (Mus musculus) 6480464 arsenite results in decreased expression of SLC6A3 mRNA and arsenite results in decreased expression of SLC6A3 protein CTD PMID:29982692 and PMID:33053406 arsenite(3-) increases response to substance ISO SLC6A3 (Homo sapiens) 6480464 SLC6A3 protein results in increased susceptibility to arsenite CTD PMID:29566083 arsenite(3-) decreases expression EXP 6480464 arsenite results in decreased expression of SLC6A3 protein CTD PMID:29982692 atrazine decreases expression EXP 6480464 Atrazine results in decreased expression of SLC6A3 mRNA and Atrazine results in decreased expression of SLC6A3 protein CTD PMID:23123945 and PMID:24863964 atrazine increases expression EXP 6480464 Atrazine results in increased expression of SLC6A3 mRNA CTD PMID:28341570 benzatropine multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 Benztropine inhibits the reaction [SLC6A3 protein results in increased uptake of Dopamine] CTD PMID:17250655 benzo[a]pyrene affects methylation ISO SLC6A3 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of SLC6A3 3' UTR and Benzo(a)pyrene affects the methylation of SLC6A3 intron CTD PMID:27901495 and PMID:30157460 benzo[a]pyrene increases methylation ISO SLC6A3 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of SLC6A3 5' UTR and Benzo(a)pyrene results in increased methylation of SLC6A3 promoter CTD PMID:27901495 benzo[e]pyrene increases methylation ISO SLC6A3 (Homo sapiens) 6480464 benzo(e)pyrene results in increased methylation of SLC6A3 intron CTD PMID:30157460 bis(2-chloroethyl) sulfide increases expression ISO Slc6a3 (Mus musculus) 6480464 Mustard Gas results in increased expression of SLC6A3 mRNA CTD PMID:15674844 bisphenol A affects localization EXP 6480464 bisphenol A affects the localization of SLC6A3 protein CTD PMID:19479021 bisphenol A multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of SLC6A3 gene CTD PMID:31601247 bisphenol A decreases methylation ISO SLC6A3 (Homo sapiens) 6480464 bisphenol A results in decreased methylation of SLC6A3 gene CTD PMID:31601247 bisphenol A increases expression ISO Slc6a3 (Mus musculus) 6480464 bisphenol A results in increased expression of SLC6A3 mRNA CTD PMID:30951980 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of SLC6A3 mRNA CTD PMID:15079872 more ... bisphenol A increases expression ISO SLC6A3 (Homo sapiens) 6480464 bisphenol A results in increased expression of SLC6A3 protein CTD PMID:27494678 bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with Estradiol] inhibits the reaction [SLC6A3 protein affects the export of Dopamine] and bisphenol A affects the reaction [SLC6A3 protein affects the export of Dopamine] CTD PMID:19479021 bisphenol F increases expression ISO Slc6a3 (Mus musculus) 6480464 bisphenol F results in increased expression of SLC6A3 mRNA CTD PMID:30951980 bupropion multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 [Bupropion co-treated with SLC6A3 protein] results in increased expression of FOS protein more ... CTD PMID:12112414 more ... bupropion affects response to substance ISO SLC6A3 (Homo sapiens) 6480464 SLC6A3 protein polymorphism affects the susceptibility to Bupropion CTD PMID:31009648 bupropion increases expression ISO SLC6A3 (Homo sapiens) 6480464 Bupropion results in increased expression of SLC6A3 protein CTD PMID:27555326 butyric acid increases expression EXP 6480464 Butyric Acid results in increased expression of SLC6A3 mRNA CTD PMID:28743636 cadmium dichloride increases expression ISO SLC6A3 (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of SLC6A3 mRNA CTD PMID:12160620 caffeine increases response to substance ISO Slc6a3 (Mus musculus) 6480464 SLC6A3 gene mutant form results in increased susceptibility to Caffeine CTD PMID:11222668 caffeine affects response to substance ISO SLC6A3 (Homo sapiens) 6480464 SLC6A3 gene polymorphism affects the susceptibility to Caffeine CTD PMID:24403155 calcitriol increases expression ISO SLC6A3 (Homo sapiens) 6480464 Calcitriol results in increased expression of SLC6A3 mRNA CTD PMID:21592394 calcitriol multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 [Testosterone co-treated with Calcitriol] results in increased expression of SLC6A3 mRNA CTD PMID:21592394 cannabidiol multiple interactions ISO Slc6a3 (Mus musculus) 6480464 Cannabidiol inhibits the reaction [Cocaine results in increased expression of SLC6A3 mRNA] CTD PMID:33427014 carbamazepine affects expression ISO SLC6A3 (Homo sapiens) 6480464 Carbamazepine affects the expression of SLC6A3 mRNA CTD PMID:25979313 CGP 52608 multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to SLC6A3 gene] CTD PMID:28238834 chlorpyrifos affects expression EXP 6480464 Chlorpyrifos affects the expression of SLC6A3 mRNA CTD PMID:18812211 chlorpyrifos decreases expression ISO Slc6a3 (Mus musculus) 6480464 Chlorpyrifos results in decreased expression of SLC6A3 mRNA CTD PMID:29156651 citalopram multiple interactions ISO Slc6a3 (Mus musculus) 6480464 SLC6A3 mutant form promotes the reaction [Citalopram results in increased abundance of Dopamine] CTD PMID:14691264 citalopram multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 [SLC6A3 protein polymorphism affects the susceptibility to Citalopram] which affects the uptake of Dopamine and Citalopram inhibits the reaction [SLC6A3 protein results in increased uptake of Dopamine] CTD PMID:31009648 citalopram affects response to substance ISO SLC6A3 (Homo sapiens) 6480464 SLC6A3 protein polymorphism affects the susceptibility to Citalopram CTD PMID:31009648 clozapine affects response to substance ISO SLC6A3 (Homo sapiens) 6480464 SLC6A3 5' UTR affects the susceptibility to Clozapine CTD PMID:20580759 cocaine multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 [Cocaine co-treated with SLC6A3 protein] results in increased expression of FOS protein more ... CTD PMID:12064476 more ... cocaine increases expression ISO Slc6a3 (Mus musculus) 6480464 Cocaine results in increased expression of SLC6A3 mRNA CTD PMID:33427014 cocaine affects response to substance ISO SLC6A3 (Homo sapiens) 6480464 SLC6A3 protein polymorphism affects the susceptibility to Cocaine CTD PMID:31009648 cocaine decreases response to substance ISO Slc6a3 (Mus musculus) 6480464 SLC6A3 gene mutant form results in decreased susceptibility to Cocaine CTD PMID:22034972 cocaine decreases expression ISO SLC6A3 (Homo sapiens) 6480464 Cocaine results in decreased expression of SLC6A3 mRNA CTD PMID:10581411 more ... cocaine decreases expression EXP 6480464 Cocaine results in decreased expression of SLC6A3 protein CTD PMID:16179556 cocaine multiple interactions EXP 6480464 Cocaine promotes the reaction [SLC6A3 protein affects the uptake of Dopamine] more ... CTD PMID:11249581 and PMID:20035724 cocaine affects expression EXP 6480464 Cocaine affects the expression of SLC6A3 mRNA and Cocaine affects the expression of SLC6A3 protein CTD PMID:11072100 and PMID:11249581 cocaine affects response to substance ISO Slc6a3 (Mus musculus) 6480464 SLC6A3 mutant form affects the susceptibility to Cocaine and SLC6A3 protein affects the susceptibility to Cocaine CTD PMID:11312315 more ... cocaine increases activity ISO Slc6a3 (Mus musculus) 6480464 Cocaine results in increased activity of SLC6A3 protein CTD PMID:11165777 cocaine multiple interactions ISO Slc6a3 (Mus musculus) 6480464 [Alcohols co-treated with Cocaine] results in increased activity of SLC6A3 protein more ... CTD PMID:11165777 more ... cocaine increases response to substance ISO SLC6A3 (Homo sapiens) 6480464 SLC6A3 gene polymorphism results in increased susceptibility to Cocaine CTD PMID:8825631 cocaine increases expression ISO SLC6A3 (Homo sapiens) 6480464 Cocaine results in increased expression of SLC6A3 protein CTD PMID:16110277 and PMID:18565692 cocaine affects binding ISO SLC6A3 (Homo sapiens) 6480464 Cocaine binds to SLC6A3 protein CTD PMID:9372557 crocidolite asbestos decreases methylation ISO SLC6A3 (Homo sapiens) 6480464 Asbestos and Crocidolite results in decreased methylation of SLC6A3 gene CTD PMID:29523930 curcumin multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 Curcumin inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of SLC6A3 protein] CTD PMID:30463061 cyhalothrin decreases expression EXP 6480464 cyhalothrin results in decreased expression of SLC6A3 protein CTD PMID:28495607 cyhalothrin increases expression EXP 6480464 cyhalothrin results in increased expression of SLC6A3 mRNA CTD PMID:36126889 DDD multiple interactions ISO Slc6a3 (Mus musculus) 6480464 Dichlorodiphenyldichloroethane inhibits the reaction [DAT protein results in increased uptake of Dopamine] CTD PMID:18533268 DDE multiple interactions EXP 6480464 [Dichlorodiphenyl Dichloroethylene co-treated with Estradiol] promotes the reaction [SLC6A3 protein affects the export of Dopamine] and Dichlorodiphenyl Dichloroethylene inhibits the reaction [SLC6A3 protein affects the export of Dopamine] CTD PMID:19479021 DDE multiple interactions ISO Slc6a3 (Mus musculus) 6480464 Dichlorodiphenyl Dichloroethylene inhibits the reaction [DAT protein results in increased uptake of Dopamine] CTD PMID:18533268 DDT multiple interactions ISO Slc6a3 (Mus musculus) 6480464 DDT inhibits the reaction [DAT protein results in increased uptake of Dopamine] CTD PMID:18533268 deguelin decreases expression ISO SLC6A3 (Homo sapiens) 6480464 deguelin results in decreased expression of SLC6A3 mRNA CTD PMID:33512557 dextran sulfate multiple interactions ISO Slc6a3 (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC6A3 mRNA CTD PMID:29950665 diazinon affects expression EXP 6480464 Diazinon affects the expression of SLC6A3 mRNA CTD PMID:18812211 diazinon increases expression EXP 6480464 Diazinon results in increased expression of SLC6A3 mRNA CTD PMID:29108742 dieldrin decreases expression ISO Slc6a3 (Mus musculus) 6480464 Dieldrin results in decreased expression of SLC6A3 protein CTD PMID:17291500 dieldrin multiple interactions EXP 6480464 Dieldrin inhibits the reaction [SLC6A3 protein affects the export of Dopamine] CTD PMID:19479021 dieldrin increases expression EXP 6480464 Dieldrin results in increased expression of SLC6A3 mRNA and Dieldrin results in increased expression of SLC6A3 protein CTD PMID:11719704 and PMID:18812211 dieldrin increases expression ISO Slc6a3 (Mus musculus) 6480464 Dieldrin results in increased expression of SLC6A3 mRNA and Dieldrin results in increased expression of SLC6A3 protein CTD PMID:16809432 diethyldithiocarbamic acid increases expression EXP 6480464 Ditiocarb results in increased expression of SLC6A3 protein CTD PMID:22874009 diethylstilbestrol multiple interactions EXP 6480464 Diethylstilbestrol affects the reaction [SLC6A3 protein affects the export of Dopamine] CTD PMID:19479021 dihydro-beta-erythroidine multiple interactions EXP 6480464 Dihydro-beta-Erythroidine affects the reaction [Nicotine results in decreased activity of SLC6A3 protein] CTD PMID:23999947 dithionite(2-) multiple interactions ISO Slc6a3 (Mus musculus) 6480464 [[Dithionite results in increased reduction of Paraquat] which co-treated with SLC6A3 protein] results in increased expression of DNM1L protein CTD PMID:35511227 dopamine multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 2-(3-methoxyphenyl)-2-(ethylamino)cyclohexanone inhibits the reaction [SLC6A3 protein results in increased uptake of Dopamine] more ... CTD PMID:12112414 more ... dopamine increases activity ISO SLC6A3 (Homo sapiens) 6480464 Dopamine results in increased activity of SLC6A3 protein CTD PMID:33785354 dopamine affects uptake ISO SLC6A3 (Homo sapiens) 6480464 SLC6A3 protein polymorphism affects the uptake of Dopamine CTD PMID:31009648 dopamine increases import ISO SLC6A3 (Homo sapiens) 6480464 SLC6A3 protein results in increased import of Dopamine CTD PMID:27555326 dopamine decreases import ISO SLC6A3 (Homo sapiens) 6480464 SLC6A3 protein mutant form results in decreased import of Dopamine CTD PMID:27555326 dopamine increases response to substance ISO SLC6A3 (Homo sapiens) 6480464 SLC6A3 protein results in increased susceptibility to Dopamine CTD PMID:23313730 dopamine increases uptake ISO SLC6A3 (Homo sapiens) 6480464 SLC6A3 protein results in increased uptake of Dopamine CTD PMID:16005927 more ... dopamine affects localization ISO SLC6A3 (Homo sapiens) 6480464 Dopamine affects the localization of SLC6A3 protein CTD PMID:20875051 dopamine increases uptake ISO Slc6a3 (Mus musculus) 6480464 DAT protein results in increased uptake of Dopamine CTD PMID:18533268 dopamine affects export EXP 6480464 SLC6A3 protein affects the export of Dopamine CTD PMID:19479021 dopamine multiple interactions EXP 6480464 [bisphenol A co-treated with Estradiol] inhibits the reaction [SLC6A3 protein affects the export of Dopamine] more ... CTD PMID:17555897 more ... dopamine affects abundance ISO Slc6a3 (Mus musculus) 6480464 SLC6A3 protein affects the abundance of Dopamine CTD PMID:18690110 dopamine multiple interactions ISO Slc6a3 (Mus musculus) 6480464 [Chlorodiphenyl (54% Chlorine) co-treated with aroclor 1260] inhibits the reaction [SLC6A3 protein results in increased uptake of Dopamine] more ... CTD PMID:11165777 more ... dopamine increases transport ISO SLC6A3 (Homo sapiens) 6480464 SLC6A3 protein results in increased transport of Dopamine CTD PMID:11707631 dopamine increases export ISO SLC6A3 (Homo sapiens) 6480464 SLC6A3 protein mutant form results in increased export of Dopamine CTD PMID:18614672 elemental selenium increases activity EXP 6480464 Selenium deficiency results in increased activity of DAT protein CTD PMID:11113527 elemental selenium increases expression EXP 6480464 Selenium deficiency results in increased expression of DAT mRNA CTD PMID:11113527 endosulfan multiple interactions EXP 6480464 Endosulfan inhibits the reaction [SLC6A3 protein affects the export of Dopamine] CTD PMID:19479021 epoxiconazole decreases expression ISO Slc6a3 (Mus musculus) 6480464 epoxiconazole results in decreased expression of SLC6A3 mRNA CTD PMID:35436446 estrone multiple interactions ISO Slc6a3 (Mus musculus) 6480464 Estrone inhibits the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:16011487 ethanol multiple interactions ISO Slc6a3 (Mus musculus) 6480464 Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of SLC6A3 protein] and Ethanol promotes the reaction [mephedrone results in decreased expression of SLC6A3 protein] CTD PMID:26747301 and PMID:34590183 ethanol decreases expression ISO Slc6a3 (Mus musculus) 6480464 Ethanol results in decreased expression of SLC6A3 protein CTD PMID:34590183 fluoxetine multiple interactions ISO Slc6a3 (Mus musculus) 6480464 SLC6A3 mutant form affects the reaction [Fluoxetine affects the abundance of Dopamine] CTD PMID:14691264 fluoxetine multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 Fluoxetine inhibits the reaction [SLC6A3 protein results in increased import of Biogenic Monoamines analog] more ... CTD PMID:28506818 and PMID:31009648 fluoxetine affects expression EXP 6480464 Fluoxetine affects the expression of SLC6A3 CTD PMID:26475043 fluoxetine affects response to substance ISO Slc6a3 (Mus musculus) 6480464 SLC6A3 protein affects the susceptibility to Fluoxetine CTD PMID:11797063 fulvestrant multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of SLC6A3 gene CTD PMID:31601247 ganglioside GM1 increases expression EXP 6480464 G(M1) Ganglioside results in increased expression of SLC6A3 mRNA CTD PMID:14552908 geraniol multiple interactions ISO Slc6a3 (Mus musculus) 6480464 geraniol inhibits the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:23943375 glyburide multiple interactions ISO Slc6a3 (Mus musculus) 6480464 Glyburide promotes the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:16725203 glyphosate increases expression ISO Slc6a3 (Mus musculus) 6480464 Glyphosate results in increased expression of SLC6A3 mRNA CTD PMID:35897073 haloperidol multiple interactions ISO Slc6a3 (Mus musculus) 6480464 SLC6A3 protein promotes the reaction [Haloperidol results in increased expression of NTS mRNA] CTD PMID:14698760 haloperidol increases expression EXP 6480464 Haloperidol results in increased expression of SLC6A3 protein CTD PMID:17069804 heptachlor multiple interactions ISO Slc6a3 (Mus musculus) 6480464 Heptachlor promotes the reaction [SLC6A3 protein results in increased uptake of Dopamine] CTD PMID:11294980 heptachlor increases expression ISO Slc6a3 (Mus musculus) 6480464 Heptachlor results in increased expression of SLC6A3 mRNA and Heptachlor results in increased expression of SLC6A3 protein CTD PMID:10499361 more ... heptachlor increases expression EXP 6480464 Heptachlor results in increased expression of SLC6A3 protein CTD PMID:11719704 herbicide decreases expression EXP 6480464 Herbicides results in decreased expression of SLC6A3 mRNA CTD PMID:23123945 ibogaine multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 Ibogaine inhibits the reaction [SLC6A3 protein mutant form results in decreased import of Dopamine] and Ibogaine promotes the reaction [SLC6A3 protein results in increased import of Dopamine] CTD PMID:27555326 ibogaine increases expression ISO SLC6A3 (Homo sapiens) 6480464 Ibogaine results in increased expression of SLC6A3 protein CTD PMID:27555326 ibuprofen multiple interactions ISO Slc6a3 (Mus musculus) 6480464 Ibuprofen inhibits the reaction [Methamphetamine results in decreased expression of SLC6A3 protein] CTD PMID:18946735 iron atom multiple interactions EXP 6480464 [manganese chloride co-treated with Iron deficiency] results in decreased expression of SLC6A3 protein CTD PMID:22479410 iron(0) multiple interactions EXP 6480464 [manganese chloride co-treated with Iron deficiency] results in decreased expression of SLC6A3 protein CTD PMID:22479410 isoliquiritigenin multiple interactions ISO Slc6a3 (Mus musculus) 6480464 isoliquiritigenin inhibits the reaction [Methamphetamine results in decreased expression of SLC6A3 protein] CTD PMID:19834288 ketamine multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 Ketamine inhibits the reaction [SLC6A3 protein results in increased uptake of Dopamine] CTD PMID:31009648 linalool decreases expression EXP 6480464 linalool results in decreased expression of SLC6A3 mRNA CTD PMID:20536181 lipopolysaccharide multiple interactions ISO Slc6a3 (Mus musculus) 6480464 LRRK2 protein affects the reaction [Lipopolysaccharides results in decreased expression of SLC6A3 protein] CTD PMID:32247534 lipopolysaccharide decreases expression ISO Slc6a3 (Mus musculus) 6480464 Lipopolysaccharides results in decreased expression of SLC6A3 protein CTD PMID:32247534 LY294002 multiple interactions ISO Slc6a3 (Mus musculus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Phentermine results in increased expression of SLC6A3 protein] CTD PMID:26887589 maneb multiple interactions ISO Slc6a3 (Mus musculus) 6480464 [Paraquat co-treated with Maneb] results in decreased expression of SLC6A3 mRNA and [Paraquat co-treated with Maneb] results in decreased expression of SLC6A3 protein CTD PMID:11124998 and PMID:18386188 maneb affects response to substance ISO SLC6A3 (Homo sapiens) 6480464 SLC6A3 gene polymorphism affects the susceptibility to Maneb CTD PMID:19590691 manganese atom decreases expression EXP 6480464 Manganese results in decreased expression of SLC6A3 protein CTD PMID:16571372 manganese atom multiple interactions ISO Slc6a3 (Mus musculus) 6480464 [manganese chloride results in increased abundance of Manganese] which results in decreased expression of SLC6A3 protein and Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of SLC6A3 protein] CTD PMID:34590183 manganese atom affects response to substance ISO SLC6A3 (Homo sapiens) 6480464 SLC6A3 gene SNP affects the susceptibility to Manganese CTD PMID:35940320 manganese atom affects localization ISO SLC6A3 (Homo sapiens) 6480464 Manganese affects the localization of SLC6A3 protein CTD PMID:23313730 manganese atom multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 LRRK2 mutant form results in increased susceptibility to [Manganese co-treated with SLC6A3 protein] CTD PMID:23628791 manganese atom increases response to substance ISO SLC6A3 (Homo sapiens) 6480464 SLC6A3 protein results in increased susceptibility to Manganese CTD PMID:18206288 manganese(0) decreases expression EXP 6480464 Manganese results in decreased expression of SLC6A3 protein CTD PMID:16571372 manganese(0) multiple interactions ISO Slc6a3 (Mus musculus) 6480464 [manganese chloride results in increased abundance of Manganese] which results in decreased expression of SLC6A3 protein and Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of SLC6A3 protein] CTD PMID:34590183 manganese(0) affects response to substance ISO SLC6A3 (Homo sapiens) 6480464 SLC6A3 gene SNP affects the susceptibility to Manganese CTD PMID:35940320 manganese(0) affects localization ISO SLC6A3 (Homo sapiens) 6480464 Manganese affects the localization of SLC6A3 protein CTD PMID:23313730 manganese(0) multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 LRRK2 mutant form results in increased susceptibility to [Manganese co-treated with SLC6A3 protein] CTD PMID:23628791 manganese(0) increases response to substance ISO SLC6A3 (Homo sapiens) 6480464 SLC6A3 protein results in increased susceptibility to Manganese CTD PMID:18206288 manganese(II) chloride multiple interactions EXP 6480464 [manganese chloride co-treated with Iron deficiency] results in decreased expression of SLC6A3 protein CTD PMID:22479410 manganese(II) chloride decreases expression EXP 6480464 manganese chloride results in decreased expression of SLC6A3 and manganese chloride results in decreased expression of SLC6A3 protein CTD PMID:16571372 more ... manganese(II) chloride decreases expression ISO Slc6a3 (Mus musculus) 6480464 manganese chloride results in decreased expression of SLC6A3 protein CTD PMID:24969583 manganese(II) chloride multiple interactions ISO Slc6a3 (Mus musculus) 6480464 [manganese chloride results in increased abundance of Manganese] which results in decreased expression of SLC6A3 protein more ... CTD PMID:24969583 and PMID:34590183 Mazindol affects binding ISO Slc6a3 (Mus musculus) 6480464 Mazindol binds to SLC6A3 protein CTD PMID:11085313 more ... Mazindol multiple interactions EXP 6480464 Methamphetamine inhibits the reaction [Mazindol binds to SLC6A3 protein] CTD PMID:9132989 Mazindol affects binding EXP 6480464 Mazindol binds to SLC6A3 protein CTD PMID:11719704 and PMID:9132989 Mazindol multiple interactions ISO Slc6a3 (Mus musculus) 6480464 Methamphetamine inhibits the reaction [Mazindol binds to SLC6A3 protein] and NOS1 protein affects the reaction [Methamphetamine inhibits the reaction [Mazindol binds to SLC6A3 protein]] CTD PMID:11085313 Mazindol multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 [Mazindol results in decreased activity of SLC6A3 protein] which results in decreased susceptibility to 1-Methyl-4-phenylpyridinium more ... CTD PMID:17250655 and PMID:18206288 Mecamylamine multiple interactions EXP 6480464 Mecamylamine affects the reaction [Nicotine results in decreased activity of SLC6A3 protein] CTD PMID:23999947 melatonin multiple interactions EXP 6480464 Melatonin inhibits the reaction [Rotenone results in decreased expression of SLC6A3 protein] CTD PMID:18289173 melatonin multiple interactions ISO Slc6a3 (Mus musculus) 6480464 Melatonin inhibits the reaction [manganese chloride results in decreased expression of SLC6A3 protein] CTD PMID:24969583 melittin increases localization ISO SLC6A3 (Homo sapiens) 6480464 Melitten results in increased localization of SLC6A3 protein CTD PMID:20969853 and PMID:22683840 melittin multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 Cocaine inhibits the reaction [Melitten results in increased localization of SLC6A3 protein] more ... CTD PMID:20969853 and PMID:22683840 mephedrone decreases expression EXP 6480464 mephedrone results in decreased expression of SLC6A3 protein CTD PMID:25817894 mephedrone decreases expression ISO Slc6a3 (Mus musculus) 6480464 mephedrone results in decreased expression of SLC6A3 protein CTD PMID:26747301 mephedrone multiple interactions ISO Slc6a3 (Mus musculus) 6480464 Ethanol promotes the reaction [mephedrone results in decreased expression of SLC6A3 protein] CTD PMID:26747301 mepyramine multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 Pyrilamine analog binds to and affects the activity of SLC6A3 protein CTD PMID:11931612 methamphetamine increases response to substance ISO SLC6A3 (Homo sapiens) 6480464 SLC6A3 3' UTR polymorphism results in increased susceptibility to Methamphetamine CTD PMID:12931138 methamphetamine increases expression ISO Slc6a3 (Mus musculus) 6480464 Methamphetamine results in increased expression of SLC6A3 protein CTD PMID:26887589 methamphetamine decreases expression ISO SLC6A3 (Homo sapiens) 6480464 Methamphetamine results in decreased expression of SLC6A3 protein CTD PMID:12944350 more ... methamphetamine decreases activity EXP 6480464 Methamphetamine results in decreased activity of SLC6A3 protein CTD PMID:11032899 more ... methamphetamine affects response to substance ISO Slc6a3 (Mus musculus) 6480464 SLC6A3 protein affects the susceptibility to Methamphetamine CTD PMID:12050851 and PMID:20558209 methamphetamine affects abundance ISO SLC6A3 (Homo sapiens) 6480464 SLC6A3 protein affects the abundance of Methamphetamine CTD PMID:11027249 methamphetamine decreases activity ISO SLC6A3 (Homo sapiens) 6480464 Methamphetamine results in decreased activity of SLC6A3 protein CTD PMID:16842981 methamphetamine multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 indatraline inhibits the reaction [SLC6A3 protein promotes the reaction [Methamphetamine results in increased activity of TAAR1 protein]] more ... CTD PMID:17234900 methamphetamine decreases expression EXP 6480464 Methamphetamine results in decreased expression of SLC6A3 protein CTD PMID:15900317 and PMID:19648469 methamphetamine increases expression EXP 6480464 Methamphetamine results in increased expression of SLC6A3 protein CTD PMID:15986185 methamphetamine multiple interactions EXP 6480464 Methamphetamine inhibits the reaction [(1R-(exo more ... CTD PMID:16897726 and PMID:9132989 methamphetamine decreases response to substance ISO Slc6a3 (Mus musculus) 6480464 SLC6A3 gene mutant form results in decreased susceptibility to Methamphetamine CTD PMID:11222668 methamphetamine decreases expression ISO Slc6a3 (Mus musculus) 6480464 Methamphetamine results in decreased expression of DAT protein more ... CTD PMID:10559418 more ... methamphetamine multiple interactions ISO Slc6a3 (Mus musculus) 6480464 15-deoxyprostaglandin J2 inhibits the reaction [Methamphetamine results in decreased expression of SLC6A3 protein] more ... CTD PMID:10559418 more ... methapyrilene increases methylation ISO SLC6A3 (Homo sapiens) 6480464 Methapyrilene results in increased methylation of SLC6A3 intron CTD PMID:30157460 methcathinone decreases expression ISO SLC6A3 (Homo sapiens) 6480464 monomethylpropion results in decreased expression of SLC6A3 protein CTD PMID:9763484 methoxychlor decreases expression ISO Slc6a3 (Mus musculus) 6480464 Methoxychlor results in decreased expression of SLC6A3 protein CTD PMID:19459224 methylmercury chloride multiple interactions ISO Slc6a3 (Mus musculus) 6480464 methylmercuric chloride inhibits the reaction [DAT protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:21385734 methylphenidate multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 [Methylphenidate co-treated with SLC6A3 protein] results in increased expression of FOS protein more ... CTD PMID:12112414 more ... methylphenidate decreases expression ISO Slc6a3 (Mus musculus) 6480464 Methylphenidate results in decreased expression of SLC6A3 mRNA CTD PMID:22470460 and PMID:33647392 methylphenidate decreases expression ISO SLC6A3 (Homo sapiens) 6480464 Methylphenidate results in decreased expression of SLC6A3 protein CTD PMID:15059031 and PMID:16139732 methylphenidate increases response to substance ISO Slc6a3 (Mus musculus) 6480464 SLC6A3 protein results in increased susceptibility to Methylphenidate CTD PMID:12699766 methylphenidate multiple interactions ISO Slc6a3 (Mus musculus) 6480464 SLC6A3 protein affects the reaction [Methylphenidate results in increased expression of FOS protein] CTD PMID:12699766 methylphenidate affects response to substance ISO SLC6A3 (Homo sapiens) 6480464 SLC6A3 3' UTR polymorphism affects the susceptibility to Methylphenidate and SLC6A3 protein polymorphism affects the susceptibility to Methylphenidate CTD PMID:19462300 and PMID:31009648 minocycline multiple interactions ISO Slc6a3 (Mus musculus) 6480464 Minocycline inhibits the reaction [Methamphetamine results in decreased expression of SLC6A3 protein] CTD PMID:16839653 modafinil affects response to substance ISO SLC6A3 (Homo sapiens) 6480464 SLC6A3 gene polymorphism affects the susceptibility to modafinil CTD PMID:24403155 modafinil multiple interactions EXP 6480464 modafinil inhibits the reaction [SLC6A3 protein affects the uptake of Dopamine] CTD PMID:19197004 modafinil decreases response to substance ISO Slc6a3 (Mus musculus) 6480464 SLC6A3 gene mutant form results in decreased susceptibility to modafinil CTD PMID:11222668 monensin A multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 Monensin promotes the reaction [para-methyl-4-methylaminorex inhibits the reaction [SLC6A3 protein results in increased uptake of 1-Methyl-4-phenylpyridinium]] CTD PMID:29908239 n-[4-(3-iodo-4-azidophenyl)butyl]-2beta-carbomethoxy-3beta-(4-chlorophenyl)tropane affects binding EXP 1625661 n-[4-(3-iodo-4-azidophenyl)butyl]-2beta-carbomethoxy-3beta-(4-chlorophenyl)tropane binds to Slc6a3 protein RGD N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [NDFIP1 protein results in decreased expression of SLC6A3 protein] CTD PMID:26300475 N-ethyl-N-nitrosourea increases mutagenesis EXP 6480464 Ethylnitrosourea results in increased mutagenesis of SLC6A3 gene CTD PMID:16495775 N-methyl-4-phenylpyridinium multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 1-Methyl-4-phenylpyridinium inhibits the reaction [(1R-(exo more ... CTD PMID:12151787 more ... N-methyl-4-phenylpyridinium decreases expression ISO SLC6A3 (Homo sapiens) 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of SLC6A3 protein CTD PMID:30463061 N-methyl-4-phenylpyridinium increases uptake EXP 6480464 SLC6A3 protein results in increased uptake of 1-Methyl-4-phenylpyridinium CTD PMID:24841869 N-methyl-4-phenylpyridinium multiple interactions EXP 6480464 4-methylaminorex inhibits the reaction [SLC6A3 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] more ... CTD PMID:24841869 N-methyl-4-phenylpyridinium increases expression ISO Slc6a3 (Mus musculus) 6480464 1-Methyl-4-phenylpyridinium results in increased expression of SLC6A3 mRNA CTD PMID:26558463 N-methyl-4-phenylpyridinium decreases expression ISO Slc6a3 (Mus musculus) 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of SLC6A3 mRNA and 1-Methyl-4-phenylpyridinium results in decreased expression of SLC6A3 protein CTD PMID:23665943 more ... N-methyl-4-phenylpyridinium affects binding ISO Slc6a3 (Mus musculus) 6480464 1-Methyl-4-phenylpyridinium binds to SLC6A3 protein CTD PMID:23665943 N-methyl-4-phenylpyridinium increases response to substance ISO SLC6A3 (Homo sapiens) 6480464 SLC6A3 protein results in increased susceptibility to 1-Methyl-4-phenylpyridinium CTD PMID:12151787 more ... N-methyl-4-phenylpyridinium decreases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of SLC6A3 protein CTD PMID:19794909 N-methyl-4-phenylpyridinium multiple interactions ISO Slc6a3 (Mus musculus) 6480464 methylmercuric chloride inhibits the reaction [DAT protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:21385734 N-methyl-4-phenylpyridinium increases uptake ISO Slc6a3 (Mus musculus) 6480464 DAT protein results in increased uptake of 1-Methyl-4-phenylpyridinium CTD PMID:21385734 N-methyl-4-phenylpyridinium increases response to substance EXP 6480464 SLC6A3 protein results in increased susceptibility to 1-Methyl-4-phenylpyridinium CTD PMID:10881039 N-methyl-4-phenylpyridinium increases uptake ISO SLC6A3 (Homo sapiens) 6480464 DAT protein results in increased uptake of 1-Methyl-4-phenylpyridinium and SLC6A3 protein results in increased uptake of 1-Methyl-4-phenylpyridinium CTD PMID:17250655 more ... N-methyl-4-phenylpyridinium affects response to substance ISO SLC6A3 (Homo sapiens) 6480464 SLC6A3 protein affects the susceptibility to 1-Methyl-4-phenylpyridinium CTD PMID:12151787 naltrexone multiple interactions ISO Slc6a3 (Mus musculus) 6480464 Naltrexone inhibits the reaction [Enkephalin and Leucine-2-Alanine inhibits the reaction [Methamphetamine results in decreased expression of SLC6A3 protein]] CTD PMID:9765353 naltrexone affects response to substance ISO SLC6A3 (Homo sapiens) 6480464 SLC6A3 gene polymorphism affects the susceptibility to Naltrexone CTD PMID:18552399 nicotine decreases expression ISO Slc6a3 (Mus musculus) 6480464 Nicotine results in decreased expression of SLC6A3 mRNA and Nicotine results in decreased expression of SLC6A3 protein CTD PMID:31945395 nicotine increases methylation ISO Slc6a3 (Mus musculus) 6480464 Nicotine results in increased methylation of SLC6A3 promoter CTD PMID:31945395 nicotine multiple interactions ISO Slc6a3 (Mus musculus) 6480464 Nicotine inhibits the reaction [Paraquat results in decreased expression of SLC6A3 protein] CTD PMID:17227438 nicotine decreases activity EXP 6480464 Nicotine results in decreased activity of SLC6A3 protein CTD PMID:23999947 nicotine multiple interactions EXP 6480464 Dihydro-beta-Erythroidine affects the reaction [Nicotine results in decreased activity of SLC6A3 protein] and Mecamylamine affects the reaction [Nicotine results in decreased activity of SLC6A3 protein] CTD PMID:23999947 nomifensine multiple interactions EXP 6480464 Nomifensine inhibits the reaction [Rotenone results in decreased expression of SLC6A3 protein] CTD PMID:18289173 nomifensine multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 [Nomifensine results in decreased activity of SLC6A3 protein] which results in decreased susceptibility to 1-Methyl-4-phenylpyridinium and Nomifensine inhibits the reaction [SLC6A3 protein results in increased uptake of Dopamine] CTD PMID:18206288 and PMID:20875051 Nonylphenol multiple interactions EXP 6480464 nonylphenol affects the reaction [SLC6A3 protein affects the export of Dopamine] CTD PMID:19479021 octopamine multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 indatraline inhibits the reaction [SLC6A3 protein promotes the reaction [Octopamine results in increased activity of TAAR1 protein]] more ... CTD PMID:17234900 oleic acid multiple interactions ISO Slc6a3 (Mus musculus) 6480464 PPARA protein promotes the reaction [Oleic Acid results in increased expression of SLC6A3 mRNA] CTD PMID:18489776 oxidopamine increases expression EXP 6480464 Oxidopamine results in increased expression of SLC6A3 mRNA and Oxidopamine results in increased expression of SLC6A3 protein CTD PMID:15303306 and PMID:34302886 oxidopamine multiple interactions EXP 6480464 Resveratrol inhibits the reaction [Oxidopamine results in increased expression of SLC6A3 protein] CTD PMID:34302886 oxidopamine increases response to substance ISO SLC6A3 (Homo sapiens) 6480464 SLC6A3 protein results in increased susceptibility to Oxidopamine CTD PMID:34252731 oxidopamine increases response to substance EXP 6480464 SLC6A3 protein results in increased susceptibility to Oxidopamine CTD PMID:10881039 oxidopamine decreases expression EXP 6480464 Oxidopamine results in decreased expression of SLC6A3 mRNA and Oxidopamine results in decreased expression of SLC6A3 protein CTD PMID:15518916 and PMID:20200117 paraquat multiple interactions ISO Slc6a3 (Mus musculus) 6480464 [[Dithionite results in increased reduction of Paraquat] which co-treated with SLC6A3 protein] results in increased expression of DNM1L protein more ... CTD PMID:11124998 more ... paraquat decreases expression EXP 6480464 Paraquat results in decreased expression of SLC6A3 mRNA CTD PMID:34655599 paraquat multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 MT2A protein inhibits the reaction [Paraquat results in decreased expression of SLC6A3 mRNA] CTD PMID:34623211 paraquat decreases expression ISO Slc6a3 (Mus musculus) 6480464 Paraquat results in decreased expression of SLC6A3 mRNA and Paraquat results in decreased expression of SLC6A3 protein CTD PMID:17227438 and PMID:20079141 paraquat increases expression EXP 6480464 Paraquat results in increased expression of SLC6A3 mRNA and Paraquat results in increased expression of SLC6A3 protein CTD PMID:20553223 and PMID:32060784 paraquat multiple interactions EXP 6480464 naringenin inhibits the reaction [Paraquat results in decreased expression of SLC6A3 mRNA] more ... CTD PMID:15985715 more ... paraquat affects response to substance ISO SLC6A3 (Homo sapiens) 6480464 SLC6A3 gene polymorphism affects the susceptibility to Paraquat CTD PMID:19590691 permethrin affects activity ISO SLC6A3 (Homo sapiens) 6480464 Permethrin affects the activity of SLC6A3 protein CTD PMID:16005927 permethrin increases expression ISO Slc6a3 (Mus musculus) 6480464 Permethrin results in increased expression of SLC6A3 protein CTD PMID:12428726 more ... permethrin decreases expression ISO Slc6a3 (Mus musculus) 6480464 Permethrin results in decreased expression of SLC6A3 protein CTD PMID:14555407 permethrin multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 Permethrin inhibits the reaction [SLC6A3 protein results in increased uptake of Dopamine] CTD PMID:16005927 phentermine multiple interactions ISO Slc6a3 (Mus musculus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Phentermine results in increased expression of SLC6A3 protein] CTD PMID:26887589 phentermine increases expression ISO Slc6a3 (Mus musculus) 6480464 Phentermine results in increased expression of SLC6A3 protein CTD PMID:26887589 phorbol 13-acetate 12-myristate multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 [Tretinoin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SLC6A3 protein and Tetradecanoylphorbol Acetate results in increased localization of [SLC6A3 protein co-treated with EEA1 protein] CTD PMID:22683840 and PMID:24101030 picoxystrobin decreases expression ISO SLC6A3 (Homo sapiens) 6480464 picoxystrobin results in decreased expression of SLC6A3 mRNA CTD PMID:33512557 piperazines multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 Piperazines analog binds to and affects the activity of SLC6A3 protein CTD PMID:11931612 piperidines affects binding ISO SLC6A3 (Homo sapiens) 6480464 Piperidines analog binds to SLC6A3 protein CTD PMID:12413863 pirinixic acid multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of SLC6A3 mRNA CTD PMID:19710929 pirinixic acid increases expression ISO Slc6a3 (Mus musculus) 6480464 pirinixic acid results in increased expression of SLC6A3 mRNA CTD PMID:17426115 pirinixic acid decreases expression EXP 6480464 pirinixic acid results in decreased expression of SLC6A3 mRNA CTD PMID:19162173 probenecid multiple interactions ISO Slc6a3 (Mus musculus) 6480464 1 more ... CTD PMID:19653878 more ... propofol decreases expression ISO Slc6a3 (Mus musculus) 6480464 Propofol results in decreased expression of SLC6A3 protein CTD PMID:32612007 quinolinic acid decreases expression EXP 6480464 Quinolinic Acid results in decreased expression of SLC6A3 protein CTD PMID:12207953 quinolinic acid increases expression EXP 6480464 Quinolinic Acid results in increased expression of SLC6A3 protein CTD PMID:12207953 quinpirole affects localization ISO SLC6A3 (Homo sapiens) 6480464 Quinpirole affects the localization of SLC6A3 protein CTD PMID:20875051 quinpirole increases expression EXP 6480464 Quinpirole results in increased expression of SLC6A3 mRNA CTD PMID:20875051 raloxifene increases expression EXP 6480464 Raloxifene Hydrochloride results in increased expression of SLC6A3 protein CTD PMID:16451217 reboxetine affects response to substance ISO Slc6a3 (Mus musculus) 6480464 SLC6A3 protein affects the susceptibility to reboxetine CTD PMID:11312315 reserpine decreases activity ISO Slc6a3 (Mus musculus) 6480464 Reserpine results in decreased activity of SLC6A3 protein CTD PMID:17664021 reserpine affects response to substance ISO Slc6a3 (Mus musculus) 6480464 SLC6A3 gene mutant form affects the susceptibility to Reserpine CTD PMID:19615345 resveratrol multiple interactions EXP 6480464 Resveratrol inhibits the reaction [Oxidopamine results in increased expression of SLC6A3 protein] CTD PMID:34302886 rotenone multiple interactions EXP 6480464 lipopolysaccharide more ... CTD PMID:18289173 and PMID:23567316 rotenone decreases expression ISO SLC6A3 (Homo sapiens) 6480464 Rotenone results in decreased expression of SLC6A3 mRNA CTD PMID:29955902 and PMID:33512557 rotenone increases expression EXP 6480464 Rotenone results in increased expression of SLC6A3 protein CTD PMID:18579341 and PMID:23567316 rotenone increases response to substance ISO SLC6A3 (Homo sapiens) 6480464 SLC6A3 protein results in increased susceptibility to Rotenone CTD PMID:18206288 rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of SLC6A3 mRNA and Rotenone results in decreased expression of SLC6A3 protein CTD PMID:18289173 and PMID:32481507 rottlerin multiple interactions ISO Slc6a3 (Mus musculus) 6480464 [rottlerin results in decreased activity of PRKCD protein] inhibits the reaction [Methamphetamine results in decreased expression of DAT protein] CTD PMID:22512859 SCH 23390 multiple interactions ISO Slc6a3 (Mus musculus) 6480464 SCH 23390 inhibits the reaction [1-(2-thienyl)-2-(methylamino)propane results in decreased expression of SLC6A3 protein] CTD PMID:30922767 selenium atom increases activity EXP 6480464 Selenium deficiency results in increased activity of DAT protein CTD PMID:11113527 selenium atom increases expression EXP 6480464 Selenium deficiency results in increased expression of DAT mRNA CTD PMID:11113527 serotonin multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 SLC6A3 protein promotes the reaction [Serotonin results in increased activity of TAAR1 protein] CTD PMID:17234900 serotonin increases uptake ISO SLC6A3 (Homo sapiens) 6480464 SLC6A3 protein results in increased uptake of Serotonin CTD PMID:17250655 simazine affects expression ISO Slc6a3 (Mus musculus) 6480464 Simazine affects the expression of SLC6A3 mRNA and Simazine affects the expression of SLC6A3 protein CTD PMID:29137186 simazine decreases expression EXP 6480464 Simazine results in decreased expression of SLC6A3 mRNA and Simazine results in decreased expression of SLC6A3 protein CTD PMID:29115391 staurosporine multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 SNCA protein affects the reaction [Staurosporine results in increased activity of SLC6A3 protein] CTD PMID:19032594 staurosporine increases activity ISO SLC6A3 (Homo sapiens) 6480464 Staurosporine results in increased activity of SLC6A3 protein CTD PMID:19032594 sulpiride multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 Sulpiride inhibits the reaction [Dopamine affects the localization of SLC6A3 protein] and Sulpiride inhibits the reaction [SLC6A3 protein results in increased uptake of Dopamine] CTD PMID:20875051 sulpiride multiple interactions ISO Slc6a3 (Mus musculus) 6480464 Sulpiride inhibits the reaction [1-(2-thienyl)-2-(methylamino)propane results in decreased expression of SLC6A3 protein] CTD PMID:30922767 tamoxifen increases expression EXP 6480464 Tamoxifen results in increased expression of SLC6A3 protein CTD PMID:16451217 telmisartan multiple interactions ISO Slc6a3 (Mus musculus) 6480464 telmisartan inhibits the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:23747572 testosterone multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 [Testosterone co-treated with Calcitriol] results in increased expression of SLC6A3 mRNA CTD PMID:21592394 testosterone increases expression ISO SLC6A3 (Homo sapiens) 6480464 Testosterone results in increased expression of SLC6A3 mRNA CTD PMID:21592394 tetrachloromethane affects expression EXP 6480464 Carbon Tetrachloride affects the expression of SLC6A3 mRNA CTD PMID:17805973 thifluzamide decreases expression ISO SLC6A3 (Homo sapiens) 6480464 thifluzamide results in decreased expression of SLC6A3 mRNA CTD PMID:33512557 titanium dioxide decreases expression ISO Slc6a3 (Mus musculus) 6480464 titanium dioxide results in decreased expression of SLC6A3 mRNA CTD PMID:29264374 titanium dioxide multiple interactions ISO Slc6a3 (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC6A3 mRNA CTD PMID:29950665 toluene affects expression EXP 6480464 Toluene affects the expression of SLC6A3 mRNA CTD PMID:18653662 trichostatin A increases expression EXP 6480464 trichostatin A results in increased expression of SLC6A3 mRNA CTD PMID:28743636 triphenyl phosphate decreases expression EXP 6480464 triphenyl phosphate results in decreased expression of SLC6A3 mRNA CTD PMID:33078273 tryptamine multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 indatraline inhibits the reaction [SLC6A3 protein promotes the reaction [tryptamine results in increased activity of TAAR1 protein]] more ... CTD PMID:17234900 tyramine multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 indatraline inhibits the reaction [SLC6A3 protein promotes the reaction [Tyramine results in increased activity of TAAR1 protein]] more ... CTD PMID:17234900 valproic acid multiple interactions EXP 6480464 Valproic Acid promotes the reaction [NR4A2 protein binds to SLC6A3 promoter] CTD PMID:28743636 valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of SLC6A3 mRNA and Valproic Acid results in increased expression of SLC6A3 protein CTD PMID:28743636 valproic acid increases methylation ISO SLC6A3 (Homo sapiens) 6480464 Valproic Acid results in increased methylation of SLC6A3 gene CTD PMID:29154799 vanoxerine dihydrochloride affects binding ISO SLC6A3 (Homo sapiens) 6480464 vanoxerine binds to SLC6A3 protein CTD PMID:11249581 vanoxerine dihydrochloride decreases response to substance ISO Slc6a3 (Mus musculus) 6480464 SLC6A3 gene mutant form results in decreased susceptibility to vanoxerine CTD PMID:11222668 vanoxerine dihydrochloride multiple interactions ISO Slc6a3 (Mus musculus) 6480464 vanoxerine inhibits the reaction [SLC6A3 protein promotes the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:22342763 vanoxerine dihydrochloride multiple interactions EXP 6480464 vanoxerine affects the reaction [Cocaine affects the expression of SLC6A3 protein] CTD PMID:11249581 vanoxerine dihydrochloride decreases activity ISO Slc6a3 (Mus musculus) 6480464 vanoxerine results in decreased activity of SLC6A3 protein CTD PMID:19616025 and PMID:22342763 vanoxerine dihydrochloride decreases activity EXP 6480464 vanoxerine results in decreased activity of SLC6A3 protein CTD PMID:18561912 vanoxerine dihydrochloride affects response to substance ISO Slc6a3 (Mus musculus) 6480464 SLC6A3 protein affects the susceptibility to vanoxerine CTD PMID:11312315 vanoxerine dihydrochloride multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 [vanoxerine results in decreased activity of SLC6A3 protein] which results in decreased susceptibility to 1-Methyl-4-phenylpyridinium and vanoxerine inhibits the reaction [SLC6A3 protein results in increased uptake of Dopamine] CTD PMID:17250655 and PMID:18206288 vinclozolin decreases methylation EXP 6480464 vinclozolin results in decreased methylation of SLC6A3 gene CTD PMID:31079544 and PMID:31682807 vorinostat increases expression ISO SLC6A3 (Homo sapiens) 6480464 vorinostat results in increased expression of SLC6A3 mRNA CTD PMID:27188386 WIN 55212-2 multiple interactions EXP 6480464 AM 251 affects the reaction [(3R)-((2 more ... CTD PMID:29113897 WIN 55212-2 affects expression EXP 6480464 (3R)-((2 more ... CTD PMID:29113897 wortmannin multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 wortmannin inhibits the reaction [SLC6A3 protein results in increased uptake of Dopamine] CTD PMID:20875051 zinc atom multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 [Amphetamine co-treated with Zinc] results in decreased localization of SLC6A3 protein CTD PMID:16684900 zinc atom increases expression EXP 6480464 Zinc results in increased expression of SLC6A3 protein CTD PMID:32060784 zinc atom multiple interactions EXP 6480464 Paraquat promotes the reaction [Zinc results in increased expression of SLC6A3 protein] and Zinc promotes the reaction [Paraquat results in increased expression of SLC6A3 protein] CTD PMID:32060784 zinc atom decreases activity ISO SLC6A3 (Homo sapiens) 6480464 Zinc results in decreased activity of SLC6A3 protein CTD PMID:16684900 zinc sulfate multiple interactions EXP 6480464 Paraquat promotes the reaction [Zinc Sulfate results in increased expression of SLC6A3 mRNA] more ... CTD PMID:20553223 zinc sulfate increases expression EXP 6480464 Zinc Sulfate results in increased expression of SLC6A3 mRNA and Zinc Sulfate results in increased expression of SLC6A3 protein CTD PMID:20553223 zinc(0) multiple interactions ISO SLC6A3 (Homo sapiens) 6480464 [Amphetamine co-treated with Zinc] results in decreased localization of SLC6A3 protein CTD PMID:16684900 zinc(0) decreases activity ISO SLC6A3 (Homo sapiens) 6480464 Zinc results in decreased activity of SLC6A3 protein CTD PMID:16684900 zinc(0) increases expression EXP 6480464 Zinc results in increased expression of SLC6A3 protein CTD PMID:32060784 zinc(0) multiple interactions EXP 6480464 Paraquat promotes the reaction [Zinc results in increased expression of SLC6A3 protein] and Zinc promotes the reaction [Paraquat results in increased expression of SLC6A3 protein] CTD PMID:32060784