(+)-catechin multiple interactions ISO RGD:737013 6480464 [epigallocatechin gallate co-treated with gallocatechol co-treated with epicatechin gallate co-treated with Catechin analog] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TLR4 protein] CTD PMID:26187476 (+)-epicatechin-3-O-gallate multiple interactions ISO RGD:737013 6480464 [epigallocatechin gallate co-treated with gallocatechol co-treated with epicatechin gallate co-treated with Catechin analog] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TLR4 protein] CTD PMID:26187476 (-)-demecolcine increases expression ISO RGD:737013 6480464 Demecolcine results in increased expression of TLR4 mRNA CTD PMID:23649840 (-)-epigallocatechin 3-gallate multiple interactions ISO RGD:737013 6480464 [epigallocatechin gallate co-treated with gallocatechol co-treated with epicatechin gallate co-treated with Catechin analog] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TLR4 protein]; more ... CTD PMID:26187476 PMID:27890776 (-)-epigallocatechin 3-gallate multiple interactions ISO RGD:737014 6480464 epigallocatechin gallate inhibits the reaction [Paraquat results in increased expression of TLR4 protein] CTD PMID:27890776 (24S)-24-hydroxycholesterol increases expression ISO RGD:737013 6480464 24-hydroxycholesterol results in increased expression of TLR4 mRNA CTD PMID:24802026 (24S)-24-hydroxycholesterol multiple interactions ISO RGD:737013 6480464 [24-hydroxycholesterol co-treated with 27-hydroxycholesterol co-treated with cholest-5-en-3 beta,7 alpha-diol] results in increased expression of TLR4 mRNA; more ... CTD PMID:24802026 (25R)-cholest-5-ene-3beta,26-diol increases expression ISO RGD:737013 6480464 27-hydroxycholesterol results in increased expression of TLR4 mRNA CTD PMID:24802026 (25R)-cholest-5-ene-3beta,26-diol multiple interactions ISO RGD:737013 6480464 [24-hydroxycholesterol co-treated with 27-hydroxycholesterol co-treated with cholest-5-en-3 beta,7 alpha-diol] results in increased expression of TLR4 mRNA; more ... CTD PMID:24802026 (R)-rosmarinic acid decreases expression EXP 6480464 rosmarinic acid results in decreased expression of TLR4 protein CTD PMID:28789951 (S)-nicotine multiple interactions EXP 6480464 Nicotine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TLR4 mRNA] CTD PMID:27984197 1,4-dithiothreitol multiple interactions ISO RGD:737014 6480464 Dithiothreitol inhibits the reaction [4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides promotes the reaction [TLR4 protein binds to TLR4 protein]]]; more ... CTD PMID:19627980 1-chloro-2,4,6-trinitrobenzene multiple interactions ISO RGD:737014 6480464 TLR2 protein affects the reaction [TLR4 protein results in increased susceptibility to Picryl Chloride] CTD PMID:18725520 1-chloro-2,4,6-trinitrobenzene increases response to substance ISO RGD:737014 6480464 TLR4 protein results in increased susceptibility to Picryl Chloride CTD PMID:18725520 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactions ISO RGD:737014 6480464 1,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased expression of TLR4 mRNA]; more ... CTD PMID:25406165 17beta-estradiol multiple interactions EXP 6480464 [bisphenol A co-treated with Estradiol] results in increased expression of TLR4 mRNA CTD PMID:26496021 17beta-hydroxy-5alpha-androstan-3-one multiple interactions ISO RGD:737013 6480464 bicalutamide inhibits the reaction [Dihydrotestosterone inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]]; more ... CTD PMID:16317058 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO RGD:737014 6480464 [2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180 co-treated with 2,4,5,2',5'-pentachlorobiphenyl] inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]; more ... CTD PMID:26141388 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:737014 6480464 [[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] which co-treated with Tetrachlorodibenzodioxin] results in decreased expression of PLAT mRNA; more ... CTD PMID:21097750 PMID:21653731 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:737014 6480464 Tetrachlorodibenzodioxin affects the expression of TLR4 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of TLR4 mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:737014 6480464 Tetrachlorodibenzodioxin results in increased expression of TLR4 mRNA CTD PMID:21093581 PMID:21653731 2,4,6-trinitrobenzenesulfonic acid increases expression ISO RGD:737014 6480464 Trinitrobenzenesulfonic Acid results in increased expression of TLR4; more ... CTD PMID:19597321 more ... 2,4,6-trinitrobenzenesulfonic acid multiple interactions EXP 6480464 Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TLR4 protein] CTD PMID:19002562 2,4,6-trinitrobenzenesulfonic acid multiple interactions ISO RGD:737014 6480464 lancemaside A inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TLR4 protein]; more ... CTD PMID:19956958 2,4,6-trinitrobenzenesulfonic acid increases expression EXP 6480464 Trinitrobenzenesulfonic Acid results in increased expression of TLR4; more ... CTD PMID:16891783 PMID:19002562 2,4,6-trinitrobenzenesulfonic acid decreases expression EXP 6480464 Trinitrobenzenesulfonic Acid results in decreased expression of TLR4 mRNA CTD PMID:19998380 2-HYDROXY-(5-([4-(2-PYRIDINYLAMINO)SULFONYL]PHENYL)AZO)BENZOIC ACID multiple interactions ISO RGD:737014 6480464 Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TLR4 protein] CTD PMID:19956958 26-hydroxycholesterol multiple interactions ISO RGD:737013 6480464 [24-hydroxycholesterol co-treated with 27-hydroxycholesterol co-treated with cholest-5-en-3 beta,7 alpha-diol] results in increased expression of TLR4 mRNA; more ... CTD PMID:24802026 26-hydroxycholesterol increases expression ISO RGD:737013 6480464 27-hydroxycholesterol results in increased expression of TLR4 mRNA CTD PMID:24802026 3,3',4,4',5-pentachlorobiphenyl affects expression ISO RGD:737013 6480464 3,4,5,3',4'-pentachlorobiphenyl affects the expression of TLR4 mRNA CTD PMID:21703328 3,3',5,5'-tetrabromobisphenol A decreases expression EXP 6480464 tetrabromobisphenol A results in decreased expression of TLR4 mRNA CTD PMID:28300664 3,4-methylenedioxymethamphetamine decreases expression ISO RGD:737014 6480464 N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of TLR4 mRNA CTD PMID:26251327 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:737013 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of TLR4 mRNA CTD PMID:28628672 4-hydroxynon-2-enal multiple interactions ISO RGD:737013 6480464 4-hydroxy-2-nonenal inhibits the reaction [TLR4 protein binds to TLR4 protein] CTD PMID:19627980 4-hydroxynon-2-enal decreases activity ISO RGD:737013 6480464 4-hydroxy-2-nonenal results in decreased activity of TLR4 protein CTD PMID:19627980 4-hydroxynon-2-enal multiple interactions ISO RGD:737014 6480464 4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides promotes the reaction [TLR4 protein binds to TLR4 protein]]; more ... CTD PMID:19627980 4-hydroxyphenyl retinamide decreases expression ISO RGD:737014 6480464 Fenretinide results in decreased expression of TLR4 mRNA CTD PMID:28973697 7alpha-hydroxycholesterol increases expression ISO RGD:737013 6480464 cholest-5-en-3 beta,7 alpha-diol results in increased expression of TLR4 mRNA CTD PMID:24802026 7alpha-hydroxycholesterol multiple interactions ISO RGD:737013 6480464 [24-hydroxycholesterol co-treated with 27-hydroxycholesterol co-treated with cholest-5-en-3 beta,7 alpha-diol] results in increased expression of TLR4 mRNA; more ... CTD PMID:24802026 acetate ester multiple interactions ISO RGD:737013 6480464 [Lipopolysaccharides results in decreased activity of TLR4 protein] inhibits the reaction [[Hyaluronic Acid metabolite binds to Acetates] which results in increased secretion of IL1B protein] CTD PMID:25053413 adenosine increases expression ISO RGD:737013 6480464 Adenosine results in increased expression of TLR4 mRNA CTD PMID:21538184 adenosine affects localization ISO RGD:737013 6480464 Adenosine affects the localization of TLR4 protein CTD PMID:21538184 adenosine multiple interactions ISO RGD:737013 6480464 Adenosine promotes the reaction [lipopolysaccharide, E. coli O26-B6 affects the localization of TLR4 protein] CTD PMID:21538184 aflatoxin B1 increases expression ISO RGD:737013 6480464 Aflatoxin B1 results in increased expression of TLR4 mRNA CTD PMID:22100608 aflatoxin B1 increases expression ISO RGD:737014 6480464 Aflatoxin B1 results in increased expression of TLR4 mRNA CTD PMID:28789997 aflatoxin B1 decreases expression ISO RGD:737013 6480464 Aflatoxin B1 results in decreased expression of TLR4 mRNA CTD PMID:28943387 aldehydo-D-glucose decreases expression ISO RGD:737013 6480464 Glucose results in decreased expression of TLR4 protein CTD PMID:20200188 aldehydo-D-glucose multiple interactions EXP 6480464 artesunate inhibits the reaction [Glucose results in increased expression of TLR4 protein] CTD PMID:30031708 aldehydo-D-glucose increases expression EXP 6480464 Glucose results in increased expression of TLR4 protein CTD PMID:30031708 aldehydo-D-glucose multiple interactions ISO RGD:737014 6480464 TLR4 affects the reaction [lipopolysaccharide, Escherichia coli O111 B4 inhibits the reaction [Glucose results in increased expression of INS2 mRNA alternative form]]; more ... CTD PMID:22558381 all-trans-retinoic acid increases expression ISO RGD:737013 6480464 Tretinoin results in increased expression of TLR4 mRNA CTD PMID:21934132 all-trans-retinol increases expression ISO RGD:737013 6480464 Vitamin A results in increased expression of TLR4 mRNA CTD PMID:17033190 alpha-D-galactose multiple interactions ISO RGD:737014 6480464 [Galactose co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of TLR4 protein; more ... CTD PMID:23535186 aluminium hydroxide multiple interactions ISO RGD:737014 6480464 TLR4 protein affects the reaction [N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine promotes the reaction [[Aluminum Hydroxide co-treated with Magnesium Hydroxide] results in increased secretion of IL2 protein]]; more ... CTD PMID:22075093 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of TLR4 mRNA CTD PMID:16483693 antirheumatic drug decreases expression ISO RGD:737013 6480464 Antirheumatic Agents results in decreased expression of TLR4 mRNA CTD PMID:24449571 arachidonic acid multiple interactions EXP 6480464 [Docosahexaenoic Acids co-treated with Arachidonic Acid] affects the expression of TLR4 mRNA; more ... CTD PMID:17515866 arsane increases expression ISO RGD:737013 6480464 Arsenic results in increased expression of TLR4 mRNA CTD PMID:19945496 PMID:27838757 arsenic atom increases expression ISO RGD:737013 6480464 Arsenic results in increased expression of TLR4 mRNA CTD PMID:19945496 PMID:27838757 arsenic(3+) increases expression ISO RGD:737013 6480464 Arsenic results in increased expression of TLR4 mRNA CTD PMID:19945496 PMID:27838757 arsenite(3-) decreases expression ISO RGD:737014 6480464 arsenite results in decreased expression of TLR4 mRNA CTD PMID:18191166 artesunate multiple interactions EXP 6480464 artesunate inhibits the reaction [Glucose results in increased expression of TLR4 protein] CTD PMID:30031708 aspalathin multiple interactions ISO RGD:737013 6480464 aspalathin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TLR4 protein] CTD PMID:25655391 atorvastatin calcium multiple interactions ISO RGD:737013 6480464 [Atorvastatin co-treated with Enalapril] results in decreased expression of TLR4 mRNA; more ... CTD PMID:20524934 atorvastatin calcium multiple interactions EXP 6480464 Atorvastatin inhibits the reaction [Paraquat results in increased expression of TLR4 mRNA]; more ... CTD PMID:27883937 atorvastatin calcium decreases expression EXP 6480464 Atorvastatin results in decreased expression of TLR4 mRNA; more ... CTD PMID:27883937 atorvastatin calcium increases expression ISO RGD:737013 6480464 Atorvastatin results in increased expression of TLR4 protein CTD PMID:16387846 auranofin multiple interactions ISO RGD:737014 6480464 Auranofin inhibits the reaction [lipopolysaccharide A promotes the reaction [TLR4 protein binds to TLR4 protein]] CTD PMID:17034761 azathioprine increases expression ISO RGD:737014 6480464 Azathioprine results in increased expression of TLR4 mRNA CTD PMID:24184165 baicalin decreases expression EXP 6480464 baicalin results in decreased expression of TLR4 protein CTD PMID:22019745 baicalin multiple interactions EXP 6480464 baicalin inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein] CTD PMID:24312512 benazepril decreases expression ISO RGD:737013 6480464 benazepril results in decreased expression of TLR4 protein CTD PMID:20981132 benzalkonium chloride increases activity ISO RGD:737014 6480464 Benzalkonium Compounds results in increased activity of TLR4 protein CTD PMID:29514330 benzo[a]pyrene increases expression ISO RGD:737014 6480464 Benzo(a)pyrene results in increased expression of TLR4 mRNA CTD PMID:22228805 benzylpenicillin multiple interactions ISO RGD:737014 6480464 [Penicillin G co-treated with Erythromycin] results in increased expression of TLR4 mRNA CTD PMID:27503388 berberine multiple interactions ISO RGD:737014 6480464 Berberine inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with TNF protein] results in increased expression of TLR4 mRNA]; more ... CTD PMID:21963898 PMID:30240693 Besigomsin multiple interactions ISO RGD:737014 6480464 schizandrol B inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of TLR4 protein] CTD PMID:24211520 bicalutamide multiple interactions ISO RGD:737013 6480464 bicalutamide inhibits the reaction [Dihydrotestosterone inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]] CTD PMID:16317058 bis(2-chloroethyl) sulfide increases expression ISO RGD:737014 6480464 Mustard Gas results in increased expression of TLR4 mRNA CTD PMID:18955075 bisdemethoxycurcumin multiple interactions ISO RGD:737013 6480464 [bis(4-hydroxycinnamoyl)methane analog co-treated with APP protein] results in increased expression of TLR4 mRNA; more ... CTD PMID:22029407 bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with Estradiol] results in increased expression of TLR4 mRNA CTD PMID:26496021 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of TLR4 mRNA CTD PMID:25181051 Bisphenol A diglycidyl ether multiple interactions EXP 6480464 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [rosiglitazone inhibits the reaction [Tobacco Smoke Pollution results in increased expression of TLR4 mRNA]]; more ... CTD PMID:24612634 bisphenol F multiple interactions ISO RGD:737013 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of TLR4 mRNA CTD PMID:28628672 bortezomib increases expression ISO RGD:737013 6480464 Bortezomib results in increased expression of TLR4 mRNA CTD PMID:17895889 butyric acid multiple interactions ISO RGD:737014 6480464 Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of TLR4 protein] CTD PMID:29751049 cadmium atom decreases expression ISO RGD:737013 6480464 Cadmium results in decreased expression of TLR4 mRNA CTD PMID:24376830 cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of TLR4 mRNA CTD PMID:25993096 PMID:29286200 cadmium dichloride increases expression ISO RGD:737014 6480464 Cadmium Chloride results in increased expression of TLR4 mRNA CTD PMID:26352046 capsaicin increases expression EXP 6480464 Capsaicin results in increased expression of TLR4 protein CTD PMID:22150557 capsaicin multiple interactions EXP 6480464 [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of TLR4 protein]; more ... CTD PMID:22150557 carbamazepine increases expression ISO RGD:737014 6480464 Carbamazepine results in increased expression of TLR4 mRNA CTD PMID:22790970 carbon nanotube multiple interactions ISO RGD:737013 6480464 Nanotubes, Carbon promotes the reaction [[K-12 lipopolysaccharide binds to and results in increased activity of TLR4 protein] which results in increased secretion of IL6 protein]; more ... CTD PMID:23266719 carbon nanotube increases expression ISO RGD:737014 6480464 Nanotubes, Carbon results in increased expression of TLR4 mRNA CTD PMID:25554681 casticin decreases expression ISO RGD:737013 6480464 casticin results in decreased expression of TLR4 mRNA CTD PMID:27862857 catalpol multiple interactions ISO RGD:737014 6480464 catalpol inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TLR4 mRNA] CTD PMID:23164921 catechin multiple interactions ISO RGD:737013 6480464 [epigallocatechin gallate co-treated with gallocatechol co-treated with epicatechin gallate co-treated with Catechin analog] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TLR4 protein] CTD PMID:26187476 cerium trichloride increases expression ISO RGD:737014 6480464 cerous chloride results in increased expression of TLR4 mRNA; more ... CTD PMID:21656643 chitosan decreases expression ISO RGD:737013 6480464 Chitosan results in decreased expression of TLR4 mRNA CTD PMID:21329777 chitosan multiple interactions ISO RGD:737013 6480464 Chitosan inhibits the reaction [Lipopolysaccharides results in decreased expression of TLR4 mRNA] CTD PMID:21329777 chlorogenic acid multiple interactions EXP 6480464 Chlorogenic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of TLR4 mRNA]; more ... CTD PMID:23146752 chlorogenic acid multiple interactions ISO RGD:737014 6480464 Chlorogenic Acid inhibits the reaction [Acetaminophen results in increased expression of TLR4 protein] CTD PMID:26079055 chlorpyrifos decreases expression EXP 6480464 Chlorpyrifos results in decreased expression of TLR4 CTD PMID:25643018 chlorpyrifos multiple interactions EXP 6480464 Chlorpyrifos promotes the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]; more ... CTD PMID:30236991 chlorpyrifos increases expression EXP 6480464 Chlorpyrifos results in increased expression of TLR4 protein CTD PMID:26524701 cholesterol multiple interactions EXP 6480464 [cocoa butter co-treated with Sodium Cholate co-treated with Cholesterol] results in increased expression of TLR4 mRNA CTD PMID:26606054 choline multiple interactions ISO RGD:737014 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of TLR4 mRNA; more ... CTD PMID:20938992 PMID:22915297 chromium atom decreases expression ISO RGD:737013 6480464 Chromium results in decreased expression of TLR4 mRNA CTD PMID:21437242 chromium(3+) decreases expression ISO RGD:737013 6480464 Chromium results in decreased expression of TLR4 mRNA CTD PMID:21437242 chrysin multiple interactions ISO RGD:737013 6480464 chrysin inhibits the reaction [nickel chloride results in increased expression of TLR4 mRNA]; more ... CTD PMID:30016632 chrysin multiple interactions EXP 6480464 chrysin inhibits the reaction [Thioacetamide results in increased expression of TLR4 mRNA] CTD PMID:30500344 cisplatin multiple interactions ISO RGD:737014 6480464 [Cisplatin co-treated with Lipopolysaccharides] results in increased expression of TLR4 protein; more ... CTD PMID:21148032 cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of TLR4 mRNA CTD PMID:28371137 cisplatin multiple interactions EXP 6480464 Grape Seed Proanthocyanidins inhibits the reaction [Cisplatin results in increased expression of TLR4 mRNA] CTD PMID:28371137 cisplatin increases expression ISO RGD:737013 6480464 Cisplatin results in increased expression of TLR4 mRNA CTD PMID:27392435 cisplatin increases expression ISO RGD:737014 6480464 Cisplatin results in increased expression of TLR4 mRNA; more ... CTD PMID:21148032 PMID:26546572 cobalt dichloride multiple interactions ISO RGD:737013 6480464 cobaltous chloride results in increased activity of [TLR4 protein binds to LY96 protein]; more ... CTD PMID:23692033 PMID:25803856 cobalt dichloride increases expression EXP 6480464 cobaltous chloride results in increased expression of TLR4 mRNA CTD PMID:24386269 copper atom multiple interactions EXP 6480464 [gadolinium chloride co-treated with Fructose co-treated with Copper deficiency] results in decreased expression of TLR4 mRNA CTD PMID:25813056 copper(0) multiple interactions EXP 6480464 [gadolinium chloride co-treated with Fructose co-treated with Copper deficiency] results in decreased expression of TLR4 mRNA CTD PMID:25813056 copper(2+) multiple interactions EXP 6480464 [gadolinium chloride co-treated with Fructose co-treated with Copper deficiency] results in decreased expression of TLR4 mRNA CTD PMID:25813056 copper(II) sulfate multiple interactions ISO RGD:737013 6480464 TLR4 protein inhibits the reaction [Copper Sulfate results in increased secretion of CXCL8 protein] CTD PMID:23692033 corticosterone multiple interactions ISO RGD:737014 6480464 [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of TLR4 protein; more ... CTD PMID:29751049 cortisol decreases expression ISO RGD:737013 6480464 Hydrocortisone results in decreased expression of TLR4 mRNA CTD PMID:17033190 crocin-1 multiple interactions EXP 6480464 crocin inhibits the reaction [Streptozocin results in increased expression of TLR4 protein] CTD PMID:29409856 curcumin multiple interactions ISO RGD:737014 6480464 Curcumin inhibits the reaction [[Lipopolysaccharides binds to TLR4 protein] which results in increased activity of IRF3 protein]; more ... CTD PMID:16678799 curcumin multiple interactions EXP 6480464 Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of TLR4 mRNA]; more ... CTD PMID:19002562 PMID:22683883 curcumin decreases expression EXP 6480464 Curcumin results in decreased expression of TLR4 mRNA; more ... CTD PMID:17965732 cyclosporin A multiple interactions ISO RGD:737014 6480464 ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [Cyclosporine results in increased expression of TLR4 mRNA]; more ... CTD PMID:27585667 cyclosporin A increases expression ISO RGD:737014 6480464 Cyclosporine results in increased expression of TLR4 mRNA; more ... CTD PMID:27585667 D-glucose decreases expression ISO RGD:737013 6480464 Glucose results in decreased expression of TLR4 protein CTD PMID:20200188 D-glucose multiple interactions EXP 6480464 artesunate inhibits the reaction [Glucose results in increased expression of TLR4 protein] CTD PMID:30031708 D-glucose increases expression EXP 6480464 Glucose results in increased expression of TLR4 protein CTD PMID:30031708 D-glucose multiple interactions ISO RGD:737014 6480464 TLR4 affects the reaction [lipopolysaccharide, Escherichia coli O111 B4 inhibits the reaction [Glucose results in increased expression of INS2 mRNA alternative form]]; more ... CTD PMID:22558381 DAPT multiple interactions EXP 6480464 N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [Oxygen deficiency results in increased expression of TLR4 mRNA] CTD PMID:24223152 daunorubicin decreases response to substance ISO RGD:737014 6480464 TLR4 protein results in decreased susceptibility to Daunorubicin CTD PMID:18789402 dehydroepiandrosterone increases expression EXP 6480464 Dehydroepiandrosterone results in increased expression of TLR4 mRNA; more ... CTD PMID:27634381 dehydroepiandrosterone multiple interactions EXP 6480464 Metformin affects the reaction [Dehydroepiandrosterone results in increased expression of TLR4 protein]; more ... CTD PMID:27634381 desferrioxamine B decreases expression ISO RGD:737013 6480464 Deferoxamine results in decreased expression of TLR4 protein CTD PMID:24170104 dexamethasone increases expression ISO RGD:737013 6480464 Dexamethasone results in increased expression of TLR4 mRNA CTD PMID:19853017 dexamethasone multiple interactions ISO RGD:737013 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of TLR4 mRNA CTD PMID:28628672 dexamethasone multiple interactions ISO RGD:737014 6480464 Dexamethasone inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein] CTD PMID:27568862 dextran sulfate multiple interactions ISO RGD:737014 6480464 Lipopolysaccharides inhibits the reaction [Dextran Sulfate results in increased expression of TLR4 protein] CTD PMID:21359540 dextran sulfate increases expression ISO RGD:737014 6480464 Dextran Sulfate results in increased expression of TLR4 protein CTD PMID:21359540 diallyl trisulfide multiple interactions ISO RGD:737014 6480464 diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein] CTD PMID:25500681 diazinon multiple interactions ISO RGD:737014 6480464 [TLR4 protein mutant form results in increased susceptibility to Diazinon] which results in decreased expression of BDNF mRNA; more ... CTD PMID:22428454 diazinon increases response to substance ISO RGD:737014 6480464 TLR4 protein mutant form results in increased susceptibility to Diazinon CTD PMID:22428454 dienogest multiple interactions ISO RGD:737013 6480464 dienogest inhibits the reaction [[Lipopolysaccharides co-treated with HMGB1 protein] results in increased expression of TLR4 mRNA] CTD PMID:22014880 dihydrogen multiple interactions EXP 6480464 Hydrogen inhibits the reaction [Chlorpyrifos promotes the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]] CTD PMID:30236991 dimethylarsinous acid increases expression ISO RGD:737013 6480464 dimethylarsinous acid results in increased expression of TLR4 mRNA CTD PMID:19945496 dioxygen multiple interactions EXP 6480464 [[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of TLR4 protein; more ... CTD PMID:23082119 more ... dioxygen multiple interactions ISO RGD:737014 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of TLR4 mRNA CTD PMID:30529165 dioxygen increases expression EXP 6480464 Oxygen deficiency results in increased expression of TLR4 mRNA CTD PMID:23082119 PMID:24223152 diprotium multiple interactions EXP 6480464 Hydrogen inhibits the reaction [Chlorpyrifos promotes the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]] CTD PMID:30236991 dorsomorphin multiple interactions ISO RGD:737013 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TLR4 mRNA CTD PMID:27188386 dorsomorphin multiple interactions ISO RGD:737014 6480464 (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [A 769662 inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]]; more ... CTD PMID:24756886 PMID:28096963 doxorubicin multiple interactions ISO RGD:737014 6480464 TLR4 protein affects the reaction [Doxorubicin results in decreased expression of GATA4 protein]; more ... CTD PMID:18321777 doxorubicin affects response to substance ISO RGD:737014 6480464 TLR4 protein affects the susceptibility to Doxorubicin CTD PMID:18321777 enalapril multiple interactions ISO RGD:737013 6480464 [Atorvastatin co-treated with Enalapril] results in decreased expression of TLR4 mRNA; more ... CTD PMID:20524934 erythromycin A increases expression ISO RGD:737014 6480464 Erythromycin results in increased expression of TLR4 mRNA CTD PMID:27503388 erythromycin A multiple interactions ISO RGD:737014 6480464 [Penicillin G co-treated with Erythromycin] results in increased expression of TLR4 mRNA CTD PMID:27503388 esculetin multiple interactions ISO RGD:737014 6480464 esculetin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TLR4 mRNA] CTD PMID:27769711 ethanol multiple interactions ISO RGD:737014 6480464 [Ethanol co-treated with isopentyl alcohol] promotes the reaction [TLR4 results in increased susceptibility to Acetaminophen]; more ... CTD PMID:16439473 more ... ethanol increases expression EXP 6480464 Ethanol results in increased expression of TLR4 mRNA; more ... CTD PMID:20861358 more ... ethanol multiple interactions EXP 6480464 ADIPOQ protein inhibits the reaction [Ethanol results in increased expression of TLR4 mRNA]; more ... CTD PMID:20861358 more ... ethanol increases expression ISO RGD:737014 6480464 Ethanol results in increased expression of TLR4 mRNA CTD PMID:24946281 ethanol increases response to substance ISO RGD:737014 6480464 TLR4 results in increased susceptibility to Ethanol CTD PMID:16439473 ethyl methanesulfonate decreases expression ISO RGD:737013 6480464 Ethyl Methanesulfonate results in decreased expression of TLR4 mRNA CTD PMID:23649840 eugenol increases expression ISO RGD:737013 6480464 Eugenol results in increased expression of TLR4 mRNA CTD PMID:17936526 ferulic acid multiple interactions ISO RGD:737014 6480464 ferulic acid inhibits the reaction [Carbon Tetrachloride results in increased expression of TLR4 mRNA]; more ... CTD PMID:21291945 flavonoids decreases expression EXP 6480464 Flavonoids results in decreased expression of TLR4 mRNA CTD PMID:18035473 folic acid multiple interactions ISO RGD:737014 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of TLR4 mRNA CTD PMID:20938992 formaldehyde multiple interactions EXP 6480464 Formaldehyde inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA] CTD PMID:25845602 PMID:27020608 fructose multiple interactions EXP 6480464 [gadolinium chloride co-treated with Fructose co-treated with Copper deficiency] results in decreased expression of TLR4 mRNA CTD PMID:25813056 fructose multiple interactions ISO RGD:737014 6480464 [Fructose co-treated with Ethanol] results in increased expression of TLR4 mRNA CTD PMID:26858005 furan increases expression EXP 6480464 furan results in increased expression of TLR4 mRNA CTD PMID:27387713 gadolinium trichloride multiple interactions EXP 6480464 [gadolinium chloride co-treated with Fructose co-treated with Copper deficiency] results in decreased expression of TLR4 mRNA; more ... CTD PMID:25813056 PMID:26177832 galactose multiple interactions ISO RGD:737014 6480464 [Galactose co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of TLR4 protein; more ... CTD PMID:23535186 gallocatechin multiple interactions ISO RGD:737013 6480464 [epigallocatechin gallate co-treated with gallocatechol co-treated with epicatechin gallate co-treated with Catechin analog] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TLR4 protein]; more ... CTD PMID:26187476 ganglioside GM1 decreases expression EXP 6480464 G(M1) Ganglioside results in decreased expression of TLR4 protein CTD PMID:16651628 geldanamycin increases expression ISO RGD:737013 6480464 geldanamycin results in increased expression of TLR4 mRNA CTD PMID:26705709 genistein decreases expression ISO RGD:737014 6480464 Genistein analog results in decreased expression of TLR4 protein CTD PMID:25447760 ginsenoside Re multiple interactions ISO RGD:737014 6480464 ginsenoside Re inhibits the reaction [Lipopolysaccharides binds to TLR4 protein] CTD PMID:22849695 glucose decreases expression ISO RGD:737013 6480464 Glucose results in decreased expression of TLR4 protein CTD PMID:20200188 glucose multiple interactions EXP 6480464 artesunate inhibits the reaction [Glucose results in increased expression of TLR4 protein] CTD PMID:30031708 glucose increases expression EXP 6480464 Glucose results in increased expression of TLR4 protein CTD PMID:30031708 glucose multiple interactions ISO RGD:737014 6480464 TLR4 affects the reaction [lipopolysaccharide, Escherichia coli O111 B4 inhibits the reaction [Glucose results in increased expression of INS2 mRNA alternative form]]; more ... CTD PMID:22558381 glutathione decreases expression ISO RGD:737013 6480464 Glutathione results in decreased expression of TLR4 mRNA CTD PMID:22385246 glycyrrhetinic acid multiple interactions ISO RGD:737014 6480464 Glycyrrhetinic Acid inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of [TLR4 protein binds to LY96 protein]] CTD PMID:28213090 halothane multiple interactions ISO RGD:737014 6480464 TLR4 protein affects the reaction [Halothane results in increased expression of IFNG protein] CTD PMID:21245496 helenalin multiple interactions ISO RGD:737014 6480464 helenalin inhibits the reaction [Lipopolysaccharides promotes the reaction [TLR4 protein binds to TLR4 protein]] CTD PMID:16678799 hexadecanoic acid multiple interactions ISO RGD:737014 6480464 Quercetin inhibits the reaction [Palmitic Acid results in increased expression of TLR4 mRNA] CTD PMID:25614714 hexadecanoic acid increases expression ISO RGD:737014 6480464 Palmitic Acid results in increased expression of TLR4 mRNA CTD PMID:25614714 hyaluronic acid multiple interactions ISO RGD:737013 6480464 [Lipopolysaccharides results in decreased activity of TLR4 protein] inhibits the reaction [[Hyaluronic Acid metabolite binds to Acetates] which results in increased secretion of IL1B protein] CTD PMID:25053413 hyaluronic acid multiple interactions ISO RGD:737014 6480464 Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [Hyaluronic Acid metabolite results in increased expression of TLR4 mRNA]; more ... CTD PMID:23692848 hyaluronic acid increases expression ISO RGD:737014 6480464 Hyaluronic Acid metabolite results in increased expression of TLR4 mRNA; more ... CTD PMID:23692848 hydroquinone multiple interactions ISO RGD:737014 6480464 hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein] CTD PMID:20054000 ifosfamide increases expression ISO RGD:737013 6480464 Ifosfamide results in increased expression of TLR4 mRNA CTD PMID:25596134 indometacin multiple interactions ISO RGD:737014 6480464 TLR4 protein affects the reaction [Indomethacin results in decreased activity of CYP1A2 protein]; more ... CTD PMID:12927920 indometacin multiple interactions ISO RGD:737013 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of TLR4 mRNA CTD PMID:28628672 irinotecan increases expression ISO RGD:737014 6480464 Irinotecan results in increased expression of TLR4 protein CTD PMID:28454924 irinotecan multiple interactions ISO RGD:737014 6480464 Silymarin inhibits the reaction [Irinotecan results in increased expression of TLR4 protein] CTD PMID:28454924 iron(2+) sulfate (anhydrous) multiple interactions ISO RGD:737014 6480464 [Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR4 mRNA; more ... CTD PMID:23692848 isoamylol multiple interactions ISO RGD:737014 6480464 [Ethanol co-treated with isopentyl alcohol] promotes the reaction [TLR4 results in increased susceptibility to Acetaminophen] CTD PMID:16439473 isoprenaline increases expression ISO RGD:737014 6480464 Isoproterenol results in increased expression of TLR4 mRNA CTD PMID:20003209 isoprenaline multiple interactions EXP 6480464 Metformin inhibits the reaction [Isoproterenol results in increased expression of TLR4 mRNA] CTD PMID:24842192 isoprenaline increases expression EXP 6480464 Isoproterenol results in increased expression of TLR4 mRNA CTD PMID:24842192 ivermectin decreases expression ISO RGD:737013 6480464 Ivermectin results in decreased expression of TLR4 mRNA CTD PMID:28653460 kaempferol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside multiple interactions ISO RGD:737013 6480464 kaempferol 3-O-sophoroside inhibits the reaction [HMGB1 protein results in increased expression of TLR4 protein] CTD PMID:22178603 ketamine multiple interactions ISO RGD:737014 6480464 TLR4 mutant form promotes the reaction [Ketamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]]; more ... CTD PMID:19540866 L-1,4-dithiothreitol multiple interactions ISO RGD:737014 6480464 Dithiothreitol inhibits the reaction [4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides promotes the reaction [TLR4 protein binds to TLR4 protein]]]; more ... CTD PMID:19627980 L-ascorbic acid multiple interactions ISO RGD:737014 6480464 [Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR4 mRNA; more ... CTD PMID:23692848 L-methionine multiple interactions ISO RGD:737014 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of TLR4 mRNA; more ... CTD PMID:20938992 PMID:22915297 lipophosphoglycan multiple interactions ISO RGD:737013 6480464 [lipopeptidophosphoglycan binds to and results in increased activity of TLR4 protein] results in increased activity of [NFKB1 protein binds to RELA protein]; more ... CTD PMID:15910421 lipophosphoglycan multiple interactions ISO RGD:737014 6480464 lipopeptidophosphoglycan binds to and results in increased activity of TLR4 protein CTD PMID:15910421 lipophosphoglycan increases response to substance ISO RGD:737014 6480464 TLR4 protein results in increased susceptibility to lipopeptidophosphoglycan CTD PMID:15910421 lipopolysaccharide decreases activity ISO RGD:737013 6480464 Lipopolysaccharides results in decreased activity of TLR4 protein CTD PMID:25053413 lipopolysaccharide increases response to substance ISO RGD:737013 6480464 TLR4 protein results in increased susceptibility to Lipopolysaccharides CTD PMID:21383675 lipopolysaccharide affects response to substance ISO RGD:737013 6480464 TLR4 protein mutant form affects the susceptibility to Lipopolysaccharides CTD PMID:10835634 lipopolysaccharide increases expression ISO RGD:737013 6480464 Lipopolysaccharides results in increased expression of TLR4 mRNA; more ... CTD PMID:16317058 more ... lipopolysaccharide increases activity ISO RGD:737013 6480464 Lipopolysaccharides results in increased activity of TLR4 protein CTD PMID:10835634 more ... lipopolysaccharide decreases expression ISO RGD:737013 6480464 Lipopolysaccharides results in decreased expression of TLR4 mRNA; more ... CTD PMID:12176910 more ... lipopolysaccharide affects binding ISO RGD:737013 6480464 Lipopolysaccharides binds to TLR4 protein CTD PMID:22180778 lipopolysaccharide multiple interactions ISO RGD:737013 6480464 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [[Lipopolysaccharides co-treated with HMGB1 protein] results in increased expression of TLR4 mRNA]; more ... CTD PMID:12574384 more ... lipopolysaccharide increases expression EXP 6480464 Lipopolysaccharides results in increased expression of TLR4 mRNA; more ... CTD PMID:12575980 more ... lipopolysaccharide decreases expression EXP 6480464 Lipopolysaccharides results in decreased expression of TLR4 mRNA; more ... CTD PMID:16309824 PMID:16651628 lipopolysaccharide decreases response to substance ISO RGD:737014 6480464 TLR4 results in decreased susceptibility to Lipopolysaccharides analog CTD PMID:22039958 lipopolysaccharide increases response to substance ISO RGD:737014 6480464 TLR4 protein results in increased susceptibility to Lipopolysaccharides CTD PMID:23000425 lipopolysaccharide affects response to substance ISO RGD:737014 6480464 TLR4 protein affects the susceptibility to Lipopolysaccharides CTD PMID:11581577 lipopolysaccharide increases localization ISO RGD:737014 6480464 Lipopolysaccharides results in increased localization of TLR4 protein CTD PMID:21276822 lipopolysaccharide increases expression ISO RGD:737014 6480464 Lipopolysaccharides results in increased expression of TLR4 mRNA; more ... CTD PMID:15665042 more ... lipopolysaccharide increases activity ISO RGD:737014 6480464 Lipopolysaccharides results in increased activity of TLR4 protein CTD PMID:12848851 more ... lipopolysaccharide decreases expression ISO RGD:737014 6480464 Lipopolysaccharides results in decreased expression of TLR4 mRNA; more ... CTD PMID:16651628 PMID:25896969 lipopolysaccharide multiple interactions EXP 6480464 [Lipopolysaccharides co-treated with sodium bisulfide] results in increased expression of TLR4 mRNA; more ... CTD PMID:17504260 more ... lipopolysaccharide affects binding ISO RGD:737014 6480464 Lipopolysaccharides binds to TLR4 protein CTD PMID:16678799 more ... lipopolysaccharide multiple interactions ISO RGD:737014 6480464 (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [A 769662 inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]]; more ... CTD PMID:11123339 more ... LY294002 multiple interactions ISO RGD:737014 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]] CTD PMID:25171655 lycopene multiple interactions ISO RGD:737013 6480464 lycopene inhibits the reaction [HMGB1 protein results in increased expression of TLR4 protein]; more ... CTD PMID:22429818 magnesium dihydroxide multiple interactions ISO RGD:737014 6480464 TLR4 protein affects the reaction [N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine promotes the reaction [[Aluminum Hydroxide co-treated with Magnesium Hydroxide] results in increased secretion of IL2 protein]]; more ... CTD PMID:22075093 melatonin multiple interactions EXP 6480464 Melatonin inhibits the reaction [tetrachlorobenzoquinone results in increased expression of TLR4 mRNA]; more ... CTD PMID:27413111 PMID:28238930 melphalan decreases expression ISO RGD:737013 6480464 Melphalan results in decreased expression of TLR4 mRNA CTD PMID:22363485 metformin multiple interactions EXP 6480464 Metformin affects the reaction [Dehydroepiandrosterone results in increased expression of TLR4 protein]; more ... CTD PMID:24842192 PMID:27634381 methadone affects binding ISO RGD:737013 6480464 Methadone binds to TLR4 protein CTD PMID:20178837 methadone increases expression EXP 6480464 Methadone results in increased expression of TLR4 mRNA; more ... CTD PMID:20178837 methadone affects response to substance EXP 6480464 Methadone affects the susceptibility to TLR4 protein CTD PMID:20178837 methadone multiple interactions ISO RGD:737013 6480464 Naloxone affects the reaction [Methadone binds to TLR4 protein] CTD PMID:20178837 methimazole multiple interactions EXP 6480464 [Buthionine Sulfoximine results in increased susceptibility to Methimazole] which results in increased expression of TLR4 protein; more ... CTD PMID:26177832 methotrexate affects expression ISO RGD:737014 6480464 Methotrexate affects the expression of TLR4 mRNA CTD PMID:18502557 methotrexate decreases expression ISO RGD:737013 6480464 Methotrexate results in decreased expression of TLR4 mRNA CTD PMID:17400583 methyl methanesulfonate decreases expression ISO RGD:737013 6480464 Methyl Methanesulfonate results in decreased expression of TLR4 mRNA CTD PMID:23649840 Methylthiouracil multiple interactions ISO RGD:737013 6480464 Methylthiouracil inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TLR4 protein] CTD PMID:26298005 morphine affects binding ISO RGD:737013 6480464 Morphine binds to TLR4 protein CTD PMID:20178837 morphine increases expression ISO RGD:737014 6480464 Morphine results in increased expression of TLR4 protein CTD PMID:24756886 morphine multiple interactions ISO RGD:737014 6480464 (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [resveratrol inhibits the reaction [Morphine results in increased expression of TLR4 protein]]; more ... CTD PMID:24756886 morphine increases expression EXP 6480464 Morphine results in increased expression of TLR4 protein CTD PMID:20178837 morphine affects response to substance EXP 6480464 Morphine affects the susceptibility to TLR4 protein CTD PMID:20178837 morphine multiple interactions ISO RGD:737013 6480464 Naloxone affects the reaction [Morphine binds to TLR4 protein] CTD PMID:20178837 Morphine-3-glucuronide multiple interactions ISO RGD:737013 6480464 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin inhibits the reaction [morphine-3-glucuronide results in increased activity of TLR4 protein]; more ... CTD PMID:19833175 Morphine-3-glucuronide increases activity ISO RGD:737013 6480464 morphine-3-glucuronide results in increased activity of TLR4 protein CTD PMID:19833175 Morphine-3-glucuronide increases expression EXP 6480464 morphine-3-glucuronide results in increased expression of TLR4 mRNA CTD PMID:19833175 muramyl dipeptide increases activity ISO RGD:737013 6480464 Acetylmuramyl-Alanyl-Isoglutamine analog results in increased activity of TLR4 protein CTD PMID:15905553 muramyl dipeptide increases response to substance ISO RGD:737014 6480464 TLR4 protein results in increased susceptibility to Acetylmuramyl-Alanyl-Isoglutamine analog CTD PMID:15905553 muramyl dipeptide increases activity ISO RGD:737014 6480464 Acetylmuramyl-Alanyl-Isoglutamine analog results in increased activity of TLR4 protein CTD PMID:15905553 N-acetyl-L-cysteine multiple interactions ISO RGD:737014 6480464 Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides promotes the reaction [TLR4 protein binds to TLR4 protein]]]; more ... CTD PMID:19627980 PMID:28495615 N-acetyl-L-cysteine decreases expression ISO RGD:737013 6480464 Acetylcysteine results in decreased expression of TLR4 mRNA CTD PMID:22385246 N-methyl-4-phenylpyridinium increases expression ISO RGD:737014 6480464 1-Methyl-4-phenylpyridinium results in increased expression of TLR4 mRNA; more ... CTD PMID:26881113 N-methyl-4-phenylpyridinium multiple interactions ISO RGD:737014 6480464 TLR4 protein affects the reaction [1-Methyl-4-phenylpyridinium results in increased secretion of IL1B protein]; more ... CTD PMID:26881113 N-methyl-N'-nitro-N-nitrosoguanidine increases expression EXP 6480464 Methylnitronitrosoguanidine results in increased expression of TLR4 mRNA CTD PMID:15120970 N-nitrosodimethylamine increases expression EXP 6480464 Dimethylnitrosamine results in increased expression of TLR4 mRNA CTD PMID:25380136 naloxone multiple interactions ISO RGD:737013 6480464 Naloxone affects the reaction [Methadone binds to TLR4 protein]; more ... CTD PMID:20178837 naproxen multiple interactions EXP 6480464 [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of TLR4 protein]; more ... CTD PMID:22150557 nickel dichloride multiple interactions ISO RGD:737013 6480464 chrysin inhibits the reaction [nickel chloride results in increased expression of TLR4 mRNA]; more ... CTD PMID:23692033 more ... nickel dichloride increases expression ISO RGD:737013 6480464 nickel chloride results in increased expression of TLR4 mRNA; more ... CTD PMID:30016632 nickel dichloride multiple interactions ISO RGD:737014 6480464 TLR4 mutant form inhibits the reaction [nickel chloride results in increased expression of TSLP protein] CTD PMID:24670797 nickel dichloride increases expression ISO RGD:737014 6480464 nickel chloride results in increased expression of TLR4 mRNA CTD PMID:24670797 nickel sulfate increases expression ISO RGD:737014 6480464 nickel sulfate results in increased expression of TLR4 protein CTD PMID:26607348 nickel sulfate multiple interactions ISO RGD:737013 6480464 TLR4 protein affects the reaction [nickel sulfate results in increased expression of EBI3 mRNA]; more ... CTD PMID:30421605 nickel sulfate multiple interactions ISO RGD:737014 6480464 puerarin inhibits the reaction [nickel sulfate results in increased expression of TLR4 protein] CTD PMID:26607348 nicotine multiple interactions EXP 6480464 Nicotine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TLR4 mRNA] CTD PMID:27984197 nitric oxide multiple interactions ISO RGD:737014 6480464 TLR4 gene mutant form inhibits the reaction [Fungal Polysaccharides results in increased abundance of Nitric Oxide]; more ... CTD PMID:22687552 PMID:23246459 Nonidet P-40 decreases expression ISO RGD:737013 6480464 Nonidet P-40 results in decreased expression of TLR4 mRNA CTD PMID:26552463 Nonylphenol decreases expression ISO RGD:737014 6480464 nonylphenol analog results in decreased expression of TLR4 mRNA CTD PMID:25242005 o-anisidine affects expression ISO RGD:737013 6480464 2-anisidine affects the expression of TLR4 mRNA CTD PMID:28089782 oxaliplatin decreases response to substance ISO RGD:737014 6480464 TLR4 protein results in decreased susceptibility to oxaliplatin CTD PMID:18789402 ozone multiple interactions ISO RGD:737014 6480464 [Lipopolysaccharides co-treated with Ozone] results in increased expression of TLR4 mRNA; more ... CTD PMID:11159012 more ... ozone affects response to substance ISO RGD:737014 6480464 TLR4 protein affects the susceptibility to Ozone CTD PMID:22300504 ozone increases expression ISO RGD:737014 6480464 Ozone results in increased expression of TLR4 mRNA CTD PMID:11159012 more ... ozone increases response to substance ISO RGD:737014 6480464 TLR4 protein results in increased susceptibility to Ozone; more ... CTD PMID:11159012 PMID:21543283 ozone decreases response to substance ISO RGD:737014 6480464 TLR4 gene mutant form results in decreased susceptibility to Ozone; more ... CTD PMID:11159012 PMID:17626835 ozone decreases expression ISO RGD:737014 6480464 Ozone results in decreased expression of TLR4 mRNA mutant form CTD PMID:11159012 paclitaxel multiple interactions ISO RGD:737014 6480464 TLR4 protein affects the reaction [Paclitaxel results in increased expression of CXCL10 mRNA]; more ... CTD PMID:11123339 PMID:28242239 paclitaxel affects response to substance ISO RGD:737014 6480464 TLR4 protein affects the susceptibility to Paclitaxel CTD PMID:11581577 paracetamol affects expression ISO RGD:737014 6480464 Acetaminophen affects the expression of TLR4 mRNA CTD PMID:17562736 paracetamol increases expression ISO RGD:737014 6480464 Acetaminophen results in increased expression of TLR4 protein CTD PMID:26079055 paracetamol increases response to substance ISO RGD:737014 6480464 TLR4 results in increased susceptibility to Acetaminophen CTD PMID:16439473 paracetamol multiple interactions ISO RGD:737014 6480464 [Ethanol co-treated with isopentyl alcohol] promotes the reaction [TLR4 results in increased susceptibility to Acetaminophen]; more ... CTD PMID:16439473 PMID:26079055 paraquat multiple interactions ISO RGD:737014 6480464 epigallocatechin gallate inhibits the reaction [Paraquat results in increased expression of TLR4 protein]; more ... CTD PMID:23969119 more ... paraquat increases expression EXP 6480464 Paraquat results in increased expression of TLR4 mRNA; more ... CTD PMID:27883937 paraquat multiple interactions EXP 6480464 Atorvastatin inhibits the reaction [Paraquat results in increased expression of TLR4 mRNA]; more ... CTD PMID:27883937 paraquat multiple interactions ISO RGD:737013 6480464 epigallocatechin gallate inhibits the reaction [Paraquat results in increased expression of TLR4 protein]; more ... CTD PMID:27890776 paraquat increases expression ISO RGD:737013 6480464 Paraquat results in increased expression of TLR4 protein CTD PMID:27890776 paraquat increases response to substance ISO RGD:737014 6480464 TLR4 results in increased susceptibility to Paraquat CTD PMID:23969119 paraquat increases expression ISO RGD:737014 6480464 Paraquat results in increased expression of TLR4 mRNA; more ... CTD PMID:23969119 more ... PD 0325901 decreases expression ISO RGD:737013 6480464 PD 0325901 results in decreased expression of TLR4 mRNA CTD PMID:25119042 PD 0325901 multiple interactions ISO RGD:737013 6480464 [PD 0325901 co-treated with (+)-JQ1 compound] results in decreased expression of TLR4 mRNA CTD PMID:25119042 permethrin multiple interactions ISO RGD:737014 6480464 [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of TLR4 protein; more ... CTD PMID:29751049 phenylmercury acetate increases expression ISO RGD:737013 6480464 Phenylmercuric Acetate results in increased expression of TLR4 mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:737013 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TLR4 mRNA CTD PMID:27188386 phenytoin decreases expression ISO RGD:737014 6480464 Phenytoin results in decreased expression of TLR4 mRNA CTD PMID:23986454 phenytoin multiple interactions ISO RGD:737014 6480464 [Phenytoin co-treated with Buthionine Sulfoximine] results in decreased expression of TLR4 mRNA CTD PMID:23986454 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:737013 6480464 [epigallocatechin gallate co-treated with gallocatechol co-treated with epicatechin gallate co-treated with Catechin analog] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TLR4 protein]; more ... CTD PMID:23680697 PMID:26187476 phorbol 13-acetate 12-myristate increases expression ISO RGD:737013 6480464 Tetradecanoylphorbol Acetate results in increased expression of TLR4 protein CTD PMID:26187476 PMID:28720485 phosphatidylinositol dimannoside multiple interactions ISO RGD:737014 6480464 TLR4 gene mutant form inhibits the reaction [[phosphatidylinositol dimannoside analog co-treated with Thioglycolates] results in increased expression of IL6 protein] CTD PMID:21936536 phosphoramide mustard increases expression EXP 6480464 phosphoramide mustard results in increased expression of TLR4 mRNA CTD PMID:27888070 picropodophyllotoxin multiple interactions ISO RGD:737014 6480464 [picropodophyllin co-treated with Lipopolysaccharides] inhibits the reaction [IGF1 protein results in decreased expression of TLR4 mRNA]; more ... CTD PMID:21371294 pirinixic acid decreases expression ISO RGD:737014 6480464 pirinixic acid results in decreased expression of TLR4 mRNA CTD PMID:16985257 polymyxin B1 multiple interactions ISO RGD:737013 6480464 Polymyxin B inhibits the reaction [[Lipopolysaccharides co-treated with HMGB1 protein] results in increased expression of TLR4 mRNA] CTD PMID:22014880 polymyxin B2 multiple interactions ISO RGD:737013 6480464 Polymyxin B inhibits the reaction [[Lipopolysaccharides co-treated with HMGB1 protein] results in increased expression of TLR4 mRNA] CTD PMID:22014880 potassium chromate decreases expression ISO RGD:737013 6480464 potassium chromate(VI) results in decreased expression of TLR4 mRNA CTD PMID:22714537 pregnenolone 16alpha-carbonitrile decreases expression EXP 6480464 Pregnenolone Carbonitrile results in decreased expression of TLR4 mRNA CTD PMID:19162173 probenecid multiple interactions ISO RGD:737014 6480464 1,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased expression of TLR4 mRNA]; more ... CTD PMID:25406165 progesterone multiple interactions ISO RGD:737013 6480464 [Proteoglycans co-treated with Progesterone] inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]; more ... CTD PMID:22014880 PMID:22314502 progesterone increases expression ISO RGD:737013 6480464 Progesterone results in increased expression of TLR4 mRNA; more ... CTD PMID:17701593 PMID:20864642 propofol multiple interactions ISO RGD:737014 6480464 Propofol inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]; more ... CTD PMID:19433076 puerarin multiple interactions ISO RGD:737014 6480464 puerarin inhibits the reaction [nickel sulfate results in increased expression of TLR4 protein] CTD PMID:26607348 Pyridostigmine bromide multiple interactions ISO RGD:737014 6480464 [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of TLR4 protein; more ... CTD PMID:29751049 quercetin multiple interactions ISO RGD:737013 6480464 Quercetin analog inhibits the reaction [24-hydroxycholesterol results in increased expression of TLR4 mRNA]; more ... CTD PMID:24802026 more ... quercetin increases expression ISO RGD:737013 6480464 Quercetin results in increased expression of TLR4 mRNA CTD PMID:21632981 quercetin multiple interactions ISO RGD:737014 6480464 Quercetin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TLR4 protein]; more ... CTD PMID:22915297 more ... quercetin decreases expression ISO RGD:737013 6480464 Quercetin results in decreased expression of TLR4 mRNA; more ... CTD PMID:20828867 PMID:27279714 quercetin multiple interactions EXP 6480464 Quercetin affects the reaction [Dehydroepiandrosterone results in increased expression of TLR4 protein]; more ... CTD PMID:27634381 reactive oxygen species multiple interactions ISO RGD:737014 6480464 [TLR4 protein affects the abundance of Reactive Oxygen Species] affects the reaction [Fungal Polysaccharides results in increased secretion of TNF protein]; more ... CTD PMID:19735705 PMID:24447977 reactive oxygen species affects abundance ISO RGD:737014 6480464 TLR4 protein affects the abundance of Reactive Oxygen Species CTD PMID:24447977 resveratrol decreases expression ISO RGD:737013 6480464 resveratrol results in decreased expression of TLR4; more ... CTD PMID:22251620 PMID:24170104 resveratrol decreases expression EXP 6480464 resveratrol results in decreased expression of TLR4 mRNA; more ... CTD PMID:22246136 PMID:26936125 resveratrol affects response to substance ISO RGD:737013 6480464 TLR4 protein affects the susceptibility to resveratrol CTD PMID:24758933 resveratrol decreases activity ISO RGD:737013 6480464 resveratrol results in decreased activity of TLR4 protein CTD PMID:24758933 resveratrol multiple interactions ISO RGD:737013 6480464 [resveratrol co-treated with [Lipopolysaccharides binds to and results in increased activity of TLR4 protein]] results in decreased secretion of IL10 protein; more ... CTD PMID:24035785 PMID:26497626 resveratrol multiple interactions EXP 6480464 resveratrol inhibits the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of TLR4 protein]; more ... CTD PMID:27064547 resveratrol decreases expression ISO RGD:737014 6480464 resveratrol results in decreased expression of TLR4 protein CTD PMID:24818579 resveratrol multiple interactions ISO RGD:737014 6480464 (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [resveratrol inhibits the reaction [Morphine results in increased expression of TLR4 protein]]; more ... CTD PMID:22118570 more ... rosmarinic acid decreases expression EXP 6480464 rosmarinic acid results in decreased expression of TLR4 protein CTD PMID:28789951 S-butyl-DL-homocysteine (S,R)-sulfoximine multiple interactions ISO RGD:737014 6480464 [Phenytoin co-treated with Buthionine Sulfoximine] results in decreased expression of TLR4 mRNA CTD PMID:23986454 S-butyl-DL-homocysteine (S,R)-sulfoximine multiple interactions EXP 6480464 [Buthionine Sulfoximine results in increased susceptibility to Methimazole] which results in increased expression of TLR4 protein; more ... CTD PMID:26177832 salvianolic acid B multiple interactions EXP 6480464 salvianolic acid B inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]; more ... CTD PMID:22101700 SB 431542 multiple interactions ISO RGD:737013 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TLR4 mRNA CTD PMID:27188386 Scoparone multiple interactions ISO RGD:737014 6480464 scoparone inhibits the reaction [[Galactose co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of TLR4 protein] CTD PMID:23535186 scopoletin multiple interactions EXP 6480464 Scopoletin inhibits the reaction [Ethanol results in increased expression of TLR4 mRNA] CTD PMID:26115886 silicon dioxide increases expression ISO RGD:737013 6480464 Silicon Dioxide analog results in increased expression of TLR4 mRNA CTD PMID:25895662 silicon dioxide decreases expression ISO RGD:737014 6480464 Silicon Dioxide results in decreased expression of TLR4 mRNA CTD PMID:19073995 simvastatin increases expression ISO RGD:737013 6480464 Simvastatin results in increased expression of TLR4 protein CTD PMID:16387846 simvastatin multiple interactions ISO RGD:737013 6480464 Simvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein] CTD PMID:16443229 simvastatin decreases expression EXP 6480464 Simvastatin results in decreased expression of TLR4 mRNA; more ... CTD PMID:19166837 sodium arsenite increases expression ISO RGD:737014 6480464 sodium arsenite results in increased expression of TLR4 mRNA CTD PMID:21134390 sodium cholate multiple interactions EXP 6480464 [cocoa butter co-treated with Sodium Cholate co-treated with Cholesterol] results in increased expression of TLR4 mRNA CTD PMID:26606054 streptozocin multiple interactions ISO RGD:737013 6480464 TNF protein inhibits the reaction [Streptozocin results in increased expression of TLR4 mRNA] CTD PMID:20446767 streptozocin increases expression EXP 6480464 Streptozocin results in increased expression of TLR4 protein CTD PMID:29409856 streptozocin multiple interactions ISO RGD:737014 6480464 [Dietary Fats co-treated with Streptozocin] results in increased expression of TLR4 mRNA; more ... CTD PMID:27769711 streptozocin multiple interactions EXP 6480464 crocin inhibits the reaction [Streptozocin results in increased expression of TLR4 protein] CTD PMID:29409856 streptozocin increases expression ISO RGD:737014 6480464 Streptozocin results in increased expression of TLR4 mRNA CTD PMID:20446767 succimer multiple interactions ISO RGD:737014 6480464 [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of TLR4 mRNA CTD PMID:21641980 sulfasalazine multiple interactions ISO RGD:737014 6480464 Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TLR4 protein] CTD PMID:19956958 sulforaphane increases expression ISO RGD:737013 6480464 sulforafan results in increased expression of TLR4 mRNA CTD PMID:26833863 sumatriptan multiple interactions EXP 6480464 [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of TLR4 protein]; more ... CTD PMID:22150557 telmisartan multiple interactions ISO RGD:737013 6480464 [Atorvastatin co-treated with Telmisartan] results in decreased expression of TLR4 mRNA; more ... CTD PMID:20524934 tert-butyl hydroperoxide multiple interactions ISO RGD:737013 6480464 1-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one inhibits the reaction [tert-Butylhydroperoxide promotes the reaction [HMGB1 protein binds to LY96 protein binds to TLR4 protein]]; more ... CTD PMID:28063877 PMID:29111459 tetrachloromethane increases expression ISO RGD:737014 6480464 Carbon Tetrachloride results in increased expression of TLR4 mRNA; more ... CTD PMID:21291945 more ... tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of TLR4 mRNA; more ... CTD PMID:17504260 more ... tetrachloromethane multiple interactions EXP 6480464 Chlorogenic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of TLR4 mRNA]; more ... CTD PMID:17504260 more ... tetrachloromethane affects expression ISO RGD:737014 6480464 Carbon Tetrachloride affects the expression of TLR4 mRNA CTD PMID:17484886 tetrachloromethane multiple interactions ISO RGD:737014 6480464 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid ethyl amide inhibits the reaction [Carbon Tetrachloride results in increased expression of TLR4 mRNA]; more ... CTD PMID:21291945 more ... tetrachloropalladate(2-) multiple interactions ISO RGD:737013 6480464 TLR4 protein affects the reaction [tetrachloropalladium results in increased secretion of CXCL8 protein] CTD PMID:23692033 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of TLR4 mRNA CTD PMID:30500344 thioacetamide multiple interactions EXP 6480464 chrysin inhibits the reaction [Thioacetamide results in increased expression of TLR4 mRNA] CTD PMID:30500344 titanium atom multiple interactions EXP 6480464 [Lipopolysaccharides co-treated with Titanium] results in decreased expression of TLR4 mRNA CTD PMID:21308757 titanium atom increases expression ISO RGD:737014 6480464 Titanium results in increased expression of TLR4 mRNA CTD PMID:20682337 toluene increases expression ISO RGD:737014 6480464 Toluene results in increased expression of TLR4 mRNA CTD PMID:21381054 valproic acid decreases methylation ISO RGD:737013 6480464 Valproic Acid results in decreased methylation of TLR4 gene CTD PMID:29154799 valproic acid increases expression ISO RGD:737013 6480464 Valproic Acid results in increased expression of TLR4 mRNA CTD PMID:28001369 valproic acid decreases expression ISO RGD:737013 6480464 Valproic Acid results in decreased expression of TLR4 mRNA CTD PMID:23179753 PMID:25716160 vinclozolin increases expression EXP 6480464 vinclozolin results in increased expression of TLR4 mRNA CTD PMID:18629315 vitamin D decreases expression ISO RGD:737013 6480464 Vitamin D results in decreased expression of TLR4 mRNA; more ... CTD PMID:23281135 vitamin D multiple interactions ISO RGD:737014 6480464 Vitamin D inhibits the reaction [Dust results in increased expression of TLR4 mRNA] CTD PMID:23281135 zinc atom increases expression EXP 6480464 Zinc deficiency results in increased expression of TLR4 mRNA CTD PMID:19111725 PMID:22689922 zinc oxide multiple interactions ISO RGD:737014 6480464 [Zinc Oxide analog co-treated with OVAL protein] results in increased expression of TLR4 protein; more ... CTD PMID:25127755 zinc protoporphyrin multiple interactions EXP 6480464 zinc protoporphyrin promotes the reaction [TLR4 protein binds to MYD88 protein] CTD PMID:25780291 zinc(0) increases expression EXP 6480464 Zinc deficiency results in increased expression of TLR4 mRNA CTD PMID:19111725 PMID:22689922 zingerone multiple interactions ISO RGD:737014 6480464 zingerone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TLR4 protein] CTD PMID:29289488
Gene-Chemical Interaction Annotations
