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Gene: Pde6b (phosphodiesterase 6B) Rattus norvegicus
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Symbol: Pde6b
Name: phosphodiesterase 6B
Description: Predicted to have 3',5'-cyclic-GMP phosphodiesterase activity. Predicted to be involved in several processes, including detection of light stimulus; regulation of cytosolic calcium ion concentration; and retina development in camera-type eye. Predicted to localize to the photoreceptor outer segment. Human ortholog(s) of this gene implicated in congenital stationary night blindness autosomal dominant 2 and retinitis pigmentosa 40. Orthologous to human PDE6B (phosphodiesterase 6B); PARTICIPATES IN altered visual phototransduction pathway; retinitis pigmentosa pathway; visual phototransduction pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; bisphenol A; cadmium dichloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC289878; phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide; phosphodiesterase 6B, cGMP-specific, rod, beta; rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta
Orthologs:
Homo sapiens (human) : PDE6B (phosphodiesterase 6B)  HGNC  Alliance
Mus musculus (house mouse) : Pde6b (phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pde6b (phosphodiesterase 6B)
Pan paniscus (bonobo/pygmy chimpanzee) : PDE6B (phosphodiesterase 6B)
Canis lupus familiaris (dog) : PDE6B (phosphodiesterase 6B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pde6b (phosphodiesterase 6B)
Sus scrofa (pig) : PDE6B (phosphodiesterase 6B)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0142,328,690 - 2,371,913 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0142,327,104 - 2,370,811 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4141,871,037 - 1,914,170 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1141,871,039 - 1,914,188 (-)NCBI
Celera141,345,195 - 1,388,316 (-)NCBICelera
Cytogenetic Map14p22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Pde6b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1311039
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-10-01
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.