Pde6b<sup>em1Baek</sup> (phosphodiesterase 6B; Cpf1-CRISPR induced mutant1, Baek) - Rat Genome Database

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Gene: Pde6bem1Baek (phosphodiesterase 6B; Cpf1-CRISPR induced mutant1, Baek) Rattus norvegicus
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Symbol: Pde6bem1Baek
Name: phosphodiesterase 6B; Cpf1-CRISPR induced mutant1, Baek
RGD ID: 42721979
Description: Cpf1-CRISPR system was injected to SD embryos to induced an 11-bp deletion in exon 1 of rat Pde6b.
ASSOCIATED WITH abnormal retina blood vessel pattern; increased retina apoptosis; retina degeneration; ASSOCIATED WITH retinitis pigmentosa
Type: allele  of Pde6b  
Previously known as: Pde6b^[em1Baek]
Is Marker For: Strains:   SD-Pde6bem1Baek  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position: No map positions available.


Disease Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. Development of a Pde6b Gene Knockout Rat Model for Studies of Degenerative Retinal Diseases. Yeo JH, etal., Invest Ophthalmol Vis Sci. 2019 Apr 1;60(5):1519-1526. doi: 10.1167/iovs.18-25556.

Genomics


Related Rat Strains
The following Strains have been annotated to Pde6bem1Baek


Expression


Sequence

Nucleotide Sequences


Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-02-25 Pde6bem1Baek  phosphodiesterase 6B; Cpf1-CRISPR induced mutant1, Baek  Pde6bem1Baek    Name changed 629549 APPROVED