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 Functional Annotation unavailable |
 Annotation Distribution unavailable |
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Functional Annotation |
Annotation Distribution |
Genomic Variants |
 Protein-Protein Interactions unavailable |
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 Damaging Variants unavailble Damaging Variants unavailable |
Protein-Protein Interactions |
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Annotation Comparison |
OLGA |
Excel (Download) |
 Gene-Chemical Interaction AnnotationsTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-catechin | multiple interactions | ISO | RGD:733150 | 6480464 | [Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of TRPC4 mRNA | CTD | PMID:24763279 | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of TRPC4 mRNA | CTD | PMID:12075121 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | RGD:733150 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression of TRPC4 mRNA | CTD | PMID:28628672 | 4-hydroxyphenyl retinamide | decreases expression | ISO | RGD:733151 | 6480464 | Fenretinide results in decreased expression of TRPC4 mRNA | CTD | PMID:28973697 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of TRPC4 mRNA | CTD | PMID:24780913 | aflatoxin B1 | decreases methylation | ISO | RGD:733150 | 6480464 | Aflatoxin B1 results in decreased methylation of TRPC4 gene | CTD | PMID:27153756 | aflatoxin B1 | increases expression | ISO | RGD:733150 | 6480464 | Aflatoxin B1 results in increased expression of TRPC4 protein | CTD | PMID:27818125 | antirheumatic drug | increases expression | ISO | RGD:733150 | 6480464 | Antirheumatic Agents results in increased expression of TRPC4 mRNA | CTD | PMID:24449571 | arachidonic acid | multiple interactions | ISO | RGD:733150 | 6480464 | TRPC4 protein affects the reaction [Arachidonic Acid results in increased transport of Calcium] | CTD | PMID:11830588 | barium(0) | multiple interactions | ISO | RGD:733150 | 6480464 | TRPC4 protein affects the reaction [Carbachol results in increased transport of Barium] | CTD | PMID:11830588 | barium(0) | increases transport | ISO | RGD:733150 | 6480464 | TRPC4 protein results in increased transport of Barium | CTD | PMID:11042129 | barium(2+) | increases transport | ISO | RGD:733150 | 6480464 | TRPC4 protein results in increased transport of Barium | CTD | PMID:11042129 | barium(2+) | multiple interactions | ISO | RGD:733150 | 6480464 | TRPC4 protein affects the reaction [Carbachol results in increased transport of Barium] | CTD | PMID:11830588 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of TRPC4 mRNA | CTD | PMID:21839799 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of TRPC4 mRNA | CTD | PMID:25181051 | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of TRPC4 gene | CTD | PMID:28505145 | calcium atom | multiple interactions | ISO | RGD:733151 | 6480464 | LEP protein promotes the reaction [TRPC4 protein results in increased transport of Calcium] | CTD | PMID:20107083 | calcium atom | multiple interactions | ISO | RGD:733150 | 6480464 | TRPC4 protein affects the reaction [Arachidonic Acid results in increased transport of Calcium]; more ... | CTD | PMID:11830588 | calcium atom | increases transport | ISO | RGD:733151 | 6480464 | TRPC4 protein results in increased transport of Calcium | CTD | PMID:20107083 | calcium(0) | multiple interactions | ISO | RGD:733151 | 6480464 | LEP protein promotes the reaction [TRPC4 protein results in increased transport of Calcium] | CTD | PMID:20107083 | calcium(0) | multiple interactions | ISO | RGD:733150 | 6480464 | TRPC4 protein affects the reaction [Arachidonic Acid results in increased transport of Calcium]; more ... | CTD | PMID:11830588 | calcium(0) | increases transport | ISO | RGD:733151 | 6480464 | TRPC4 protein results in increased transport of Calcium | CTD | PMID:20107083 | carbachol | multiple interactions | ISO | RGD:733150 | 6480464 | TRPC4 protein affects the reaction [Carbachol results in increased transport of Barium]; more ... | CTD | PMID:11830588 | carbachol | increases response to substance | ISO | RGD:733150 | 6480464 | TRPC4 protein results in increased susceptibility to Carbachol | CTD | PMID:29658714 | carbachol | increases activity | ISO | RGD:733150 | 6480464 | Carbachol results in increased activity of TRPC4 protein | CTD | PMID:29658714 | catechin | multiple interactions | ISO | RGD:733150 | 6480464 | [Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of TRPC4 mRNA | CTD | PMID:24763279 | chlorpyrifos | affects expression | EXP | | 6480464 | Chlorpyrifos affects the expression of TRPC4 mRNA | CTD | PMID:22611033 | dexamethasone | multiple interactions | ISO | RGD:733150 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression of TRPC4 mRNA | CTD | PMID:28628672 | dorsomorphin | multiple interactions | ISO | RGD:733150 | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TRPC4 mRNA; more ... | CTD | PMID:27188386 | elemental selenium | decreases expression | ISO | RGD:733150 | 6480464 | Selenium results in decreased expression of TRPC4 mRNA | CTD | PMID:19244175 | indometacin | multiple interactions | ISO | RGD:733150 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression of TRPC4 mRNA | CTD | PMID:28628672 | lead diacetate | increases expression | EXP | | 6480464 | lead acetate results in increased expression of TRPC4 mRNA; more ... | CTD | PMID:22674931 | Malaoxon | increases expression | EXP | | 6480464 | malaoxon results in increased expression of TRPC4 mRNA; more ... | CTD | PMID:22674931 | malathion | increases expression | EXP | | 6480464 | Malathion results in increased expression of TRPC4 mRNA; more ... | CTD | PMID:22674931 | mercury dibromide | decreases expression | ISO | RGD:733150 | 6480464 | mercuric bromide results in decreased expression of TRPC4 mRNA | CTD | PMID:26272509 | mercury dibromide | multiple interactions | ISO | RGD:733150 | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TRPC4 mRNA | CTD | PMID:27188386 | mercury dichloride | increases activity | ISO | RGD:733151 | 6480464 | Mercuric Chloride results in increased activity of TRPC4 protein | CTD | PMID:21984481 | mercury dichloride | multiple interactions | ISO | RGD:733151 | 6480464 | 2-aminoethoxydiphenyl borate inhibits the reaction [Mercuric Chloride results in increased activity of TRPC4 protein] | CTD | PMID:21984481 | methoxychlor | increases methylation | EXP | | 6480464 | Methoxychlor results in increased methylation of TRPC4 gene | CTD | PMID:23303685 | N-methyl-4-phenylpyridinium | decreases expression | ISO | RGD:733150 | 6480464 | 1-Methyl-4-phenylpyridinium results in decreased expression of TRPC4 mRNA | CTD | PMID:24810058 | p-chloromercuribenzoic acid | decreases expression | ISO | RGD:733150 | 6480464 | p-Chloromercuribenzoic Acid results in decreased expression of TRPC4 mRNA | CTD | PMID:26272509 | p-chloromercuribenzoic acid | multiple interactions | ISO | RGD:733150 | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TRPC4 mRNA | CTD | PMID:27188386 | panobinostat | multiple interactions | ISO | RGD:733150 | 6480464 | [NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TRPC4 mRNA | CTD | PMID:27188386 | panobinostat | decreases expression | ISO | RGD:733150 | 6480464 | panobinostat results in decreased expression of TRPC4 mRNA | CTD | PMID:26272509 | phenylmercury acetate | decreases expression | ISO | RGD:733150 | 6480464 | Phenylmercuric Acetate results in decreased expression of TRPC4 mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | RGD:733150 | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TRPC4 mRNA | CTD | PMID:27188386 | potassium chromate | decreases expression | ISO | RGD:733150 | 6480464 | potassium chromate(VI) results in decreased expression of TRPC4 mRNA | CTD | PMID:22714537 | potassium dichromate | increases expression | ISO | RGD:733151 | 6480464 | Potassium Dichromate results in increased expression of TRPC4 mRNA | CTD | PMID:23608068 | progesterone | increases expression | ISO | RGD:733150 | 6480464 | Progesterone results in increased expression of TRPC4 mRNA | CTD | PMID:18070364 | Ptaquiloside | decreases expression | ISO | RGD:733151 | 6480464 | ptaquiloside results in decreased expression of TRPC4 mRNA | CTD | PMID:23274088 | SB 431542 | multiple interactions | ISO | RGD:733150 | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TRPC4 mRNA; more ... | CTD | PMID:27188386 | selenium atom | decreases expression | ISO | RGD:733150 | 6480464 | Selenium results in decreased expression of TRPC4 mRNA | CTD | PMID:19244175 | strontium atom | multiple interactions | ISO | RGD:733150 | 6480464 | TRPC4 protein affects the reaction [1-oleoyl-2-acetylglycerol results in increased transport of Strontium] | CTD | PMID:11830588 | strontium(2+) | multiple interactions | ISO | RGD:733150 | 6480464 | TRPC4 protein affects the reaction [1-oleoyl-2-acetylglycerol results in increased transport of Strontium] | CTD | PMID:11830588 | trichostatin A | decreases expression | ISO | RGD:733150 | 6480464 | trichostatin A results in decreased expression of TRPC4 mRNA | CTD | PMID:24935251 PMID:26272509 | trichostatin A | multiple interactions | ISO | RGD:733150 | 6480464 | [NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TRPC4 mRNA | CTD | PMID:27188386 | valproic acid | affects expression | ISO | RGD:733150 | 6480464 | Valproic Acid affects the expression of TRPC4 mRNA | CTD | PMID:25979313 | valproic acid | decreases expression | ISO | RGD:733150 | 6480464 | Valproic Acid results in decreased expression of TRPC4 mRNA | CTD | PMID:24383497 more ... | vorinostat | increases expression | ISO | RGD:733150 | 6480464 | vorinostat results in increased expression of TRPC4 mRNA | CTD | PMID:27188386 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene Ontology AnnotationsDisease AnnotationsGene-Chemical Interaction Annotations
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Gene Ontology Annotations
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References - curated| 1. | Funayama M, etal., Brain Res Mol Brain Res 1996 Dec 31;43(1-2):259-66. |
| 2. | GOA data from the GO Consortium |
| 3. | MGD data from the GO Consortium |
| 4. | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
| 5. | RGD automated data pipeline |
| 6. | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 7. | RGD automated import pipeline for gene-chemical interactions |
| 8. | Satoh E, etal., Circ J 2002 Oct;66(10):954-8. |
| 9. | Schaefer M, etal., J Biol Chem 2002 Feb 1;277(5):3752-9. |
| 10. | Tang Y, etal., J Biol Chem 2000 Dec 1;275(48):37559-64. |
References - uncurated| PubMed | 10998353 11301024 11897792 14505576 14668438 15044151 16254212 17141310 17416589 17593972 17928298 18538797 19139271 19996314 20164195 20662729 21873635 22534489 22611033 23526217 23677990 23922735 24113457 24352411 24388923 25049082 26988269 27083517 27129253 27641617 |
RGD Disease Portals| Trpc4 has been annotated in the following RGD Disease Portals. |
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Candidate Gene StatusComparative Map Data| Trpc4 (Rattus norvegicus - Norway rat) |
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| TRPC4 (Homo sapiens - human) |
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| Trpc4 (Mus musculus - house mouse) |
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| Trpc4 (Chinchilla lanigera - long-tailed chinchilla) |
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| TRPC4 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| TRPC4 (Canis lupus familiaris - dog) |
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| Trpc4 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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Position Markers| RH134901 |
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| Trpc4 |
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| Trpc4 |
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QTLs in Region (Rnor_6.0)| The following QTLs overlap with this region. |  | Full Report | | CSV | | TAB | | Printer | | Gviewer |
Genetic ModelsmiRNA Target Status
| The detailed report is available here: | | Full Report | | CSV | | TAB | | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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Nucleotide Sequences| RefSeq Transcripts | NM_001083115 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| NM_080396 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_006232356 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_008761008 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_017591143 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_017591144 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| GenBank Nucleotide | AABR07010609 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| AABR07010610 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AABR07010611 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AABR07072729 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01017059 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01017060 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01017061 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01017062 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01017063 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01017064 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01017065 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01017066 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01017067 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AB008889 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AC118066 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AF288407 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AF288408 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AF421363 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AF421364 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AF421365 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AF421366 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AF421367 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AF421368 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| CH474003 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| FQ228645 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| RefSeq Acc Id: | NM_080396 | ||||||||||||||||||||||||
| RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||||||
| Position: |
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| Sequence: |
AGCATGGCTCAGTTCTATTACAAACGAAATGTCAACGCCCCCTACCGAGACCGCATCCCACTGAhide sequence |
| RefSeq Acc Id: | NM_001083115 | ||||||||||||||||||||||||
| RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||||||
| Position: |
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| Sequence: |
AGCATGGCTCAGTTCTATTACAAACGAAATGTCAACGCCCCCTACCGAGACCGCATCCCACTGAhide sequence |
| RefSeq Acc Id: | XM_006232356 | ||||||||||||||
| RefSeq Status: | |||||||||||||||
| Type: | CODING | ||||||||||||||
| Position: |
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| Sequence: |
CATCAGTGCTGGGTGGGAGAGGCTGTCGTCCTGGGCACCCCGCCCCCTCCTGGGCCGCCCCTCChide sequence |
| RefSeq Acc Id: | XM_006232357 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| Sequence: |
CCCTGCTCTGGCTCTCCAGCATCCTCACTCCGCCCAGTTCTGTGCCAGCTGCGTGGGCTCTGGThide sequence |
| RefSeq Acc Id: | XM_008761008 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| Sequence: |
CATCAGTGCTGGGTGGGAGAGGCTGTCGTCCTGGGCACCCCGCCCCCTCCTGGGCCGCCCCTCChide sequence |
| RefSeq Acc Id: | XM_017591143 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| RefSeq Acc Id: | XM_017591144 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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Protein Sequences| Protein RefSeqs | NP_001076584 | (Get FASTA) | NCBI Sequence Viewer |
| NP_536321 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_006232418 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_008759230 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_017446632 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_017446633 | (Get FASTA) | NCBI Sequence Viewer | |
| GenBank Protein | AAG21809 | (Get FASTA) | NCBI Sequence Viewer |
| AAG21810 | (Get FASTA) | NCBI Sequence Viewer | |
| AAL24554 | (Get FASTA) | NCBI Sequence Viewer | |
| AAL24555 | (Get FASTA) | NCBI Sequence Viewer | |
| AAL24556 | (Get FASTA) | NCBI Sequence Viewer | |
| AAL24557 | (Get FASTA) | NCBI Sequence Viewer | |
| AAL24558 | (Get FASTA) | NCBI Sequence Viewer | |
| AAL24559 | (Get FASTA) | NCBI Sequence Viewer | |
| BAA23599 | (Get FASTA) | NCBI Sequence Viewer | |
| EDM14938 | (Get FASTA) | NCBI Sequence Viewer | |
| EDM14939 | (Get FASTA) | NCBI Sequence Viewer | |
| EDM14940 | (Get FASTA) | NCBI Sequence Viewer | |
| EDM14941 | (Get FASTA) | NCBI Sequence Viewer | |
| O35119 | (Get FASTA) | NCBI Sequence Viewer |
| Protein Acc Id: | NP_536321 |
| Peptide Label: | isoform alpha |
| Sequence: |
MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININhide sequence |
| Protein Acc Id: | NP_001076584 |
| Peptide Label: | isoform beta |
| Sequence: |
MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININhide sequence |
| Protein Acc Id: | XP_006232418 |
| Peptide Label: | isoform X1 |
| Sequence: |
MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININhide sequence |
| Protein Acc Id: | XP_006232419 |
| Sequence: |
MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININhide sequence |
| Protein Acc Id: | XP_008759230 |
| Peptide Label: | isoform X2 |
| Sequence: |
MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININhide sequence |
| Protein Acc Id: | XP_017446632 |
| Peptide Label: | isoform X3 |
| Protein Acc Id: | XP_017446633 |
| Peptide Label: | isoform X4 |
TranscriptomeStrain Sequence Variants (Rnor 5.0)
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External Database Links| Database | Acc Id | Source(s) |
| Ensembl Genes | ENSRNOG00000011133 | ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Protein | ENSRNOP00000015437 | ENTREZGENE, UniProtKB/TrEMBL |
| ENSRNOP00000042886 | ENTREZGENE, UniProtKB/TrEMBL | |
| Ensembl Transcript | ENSRNOT00000015437 | ENTREZGENE, UniProtKB/TrEMBL |
| ENSRNOT00000044028 | ENTREZGENE, UniProtKB/TrEMBL | |
| Gene3D-CATH | 1.25.40.20 | UniProtKB/Swiss-Prot |
| InterPro | Ankyrin_rpt | UniProtKB/Swiss-Prot |
| Ankyrin_rpt-contain_dom | UniProtKB/Swiss-Prot | |
| Ankyrin_rpt-contain_sf | UniProtKB/Swiss-Prot | |
| Ion_trans | UniProtKB/Swiss-Prot | |
| Trans_rcpt | UniProtKB/Swiss-Prot | |
| TRP_2 | UniProtKB/Swiss-Prot | |
| TRP_channel | UniProtKB/Swiss-Prot | |
| TRP_channel4 | UniProtKB/Swiss-Prot | |
| KEGG Report | rno:84494 | UniProtKB/TrEMBL |
| NCBI Gene | 84494 | ENTREZGENE |
| PANTHER | PTHR10117 | UniProtKB/Swiss-Prot |
| PTHR10117:SF25 | UniProtKB/Swiss-Prot | |
| Pfam | Ion_trans | UniProtKB/Swiss-Prot |
| TRP_2 | UniProtKB/Swiss-Prot | |
| PhenoGen | Trpc4 | PhenoGen |
| PRINTS | TRNSRECEPTRP | UniProtKB/Swiss-Prot |
| TRPCHANNEL4 | UniProtKB/Swiss-Prot | |
| PROSITE | ANK_REP_REGION | UniProtKB/Swiss-Prot |
| ANK_REPEAT | UniProtKB/Swiss-Prot | |
| SMART | ANK | UniProtKB/Swiss-Prot |
| Superfamily-SCOP | ANK | UniProtKB/Swiss-Prot |
| TIGRFAMs | trp | UniProtKB/Swiss-Prot |
| Transposagen | Trpc4 |
Transposagen |
| UniGene | Rn.10853 | ENTREZGENE |
| UniProt | O35119 | ENTREZGENE |
| Q91ZM0 | ENTREZGENE, UniProtKB/TrEMBL | |
| Q91ZM1 | ENTREZGENE, UniProtKB/TrEMBL | |
| TRPC4_RAT | UniProtKB/Swiss-Prot | |
| UniProt Secondary | Q9EQ74 | UniProtKB/Swiss-Prot |
| Q9EQ75 | UniProtKB/Swiss-Prot |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2004-09-10 | Trpc4 | transient receptor potential cation channel, subfamily C, member 4 | transient receptor protein 4 | Name updated | 1299863 | APPROVED | |
| 2002-08-07 | Trpc4 | transient receptor protein 4 | Symbol and Name status set to provisional | 70820 | PROVISIONAL |
RGD Curation Notes| Note Type | Note | Reference |
|---|---|---|
| gene_transcript | splice variant Trpc4beta forms a homomultimeric cation channel | 625475 |
| gene_transcript | splice variants Trpc4alpha and Trpc4beta display receptor mediated activation of calcium transport activity | 625475 |
| More on Trpc4 | |
|
Alliance Gene |
|
NCBI Gene |
|
Ensembl Gene |
|
|
JBrowse: rn5 rn6 |
|
NCBI Genome Data Viewer |
| RGD Object Information | |
| RGD ID: | 621276 |
| Created: | 2002-08-06 |
| Species: | Rattus norvegicus |
| Last Modified: | 2018-07-10 |
| Status: | ACTIVE |
© Medical College of Wisconsin
RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.
