Cftr Rat (R,R,R)-alpha-tocopherol multiple interactions ISO CFTR (Homo sapiens) 6480464 alpha-Tocopherol inhibits the reaction [Cadmium results in decreased expression of CFTR protein] CTD PMID:20363832 Cftr Rat (S)-naringenin multiple interactions ISO CFTR (Homo sapiens) 6480464 naringenin inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in decreased expression of CFTR mRNA] and naringenin inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in decreased expression of CFTR protein] CTD PMID:31301536 Cftr Rat 1,1'-azobis(N,N-dimethylformamide) multiple interactions ISO CFTR (Homo sapiens) 6480464 [Glutathione co-treated with Diamide] results in decreased activity of CFTR protein CTD PMID:15857825 Cftr Rat 1,10-phenanthroline increases activity ISO CFTR (Homo sapiens) 6480464 1 and 10-phenanthroline results in increased activity of CFTR protein CTD PMID:15921678 Cftr Rat 1,2-dichloroethane decreases expression ISO Cftr (Mus musculus) 6480464 ethylene dichloride results in decreased expression of CFTR mRNA CTD PMID:28960355 Cftr Rat 1,4-dithiothreitol multiple interactions ISO CFTR (Homo sapiens) 6480464 Dithiothreitol inhibits the reaction [Glutathione results in decreased activity of CFTR protein] CTD PMID:15657297 Cftr Rat 17alpha-ethynylestradiol increases expression ISO Cftr (Mus musculus) 6480464 Ethinyl Estradiol results in increased expression of CFTR mRNA CTD PMID:17555576 and PMID:17942748 Cftr Rat 17alpha-ethynylestradiol multiple interactions ISO Cftr (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CFTR mRNA CTD PMID:17942748 Cftr Rat 17beta-estradiol increases expression ISO CFTR (Homo sapiens) 6480464 Estradiol results in increased expression of CFTR mRNA and Estradiol results in increased expression of CFTR protein CTD PMID:15471937 Cftr Rat 17beta-estradiol multiple interactions EXP 6480464 [bisphenol A co-treated with Estradiol] results in increased expression of CFTR mRNA CTD PMID:26496021 Cftr Rat 17beta-estradiol affects expression ISO Cftr (Mus musculus) 6480464 Estradiol affects the expression of CFTR mRNA CTD PMID:15598610 Cftr Rat 17beta-estradiol increases expression ISO Cftr (Mus musculus) 6480464 Estradiol results in increased expression of CFTR mRNA CTD PMID:15289156 Cftr Rat 17beta-estradiol multiple interactions ISO CFTR (Homo sapiens) 6480464 [Progesterone co-treated with Estradiol] results in decreased expression of CFTR mRNA CTD PMID:17404688 Cftr Rat 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Cftr (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CFTR mRNA CTD PMID:17942748 Cftr Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Cftr (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of CFTR mRNA CTD PMID:21570461 and PMID:26377647 Cftr Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO CFTR (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in increased expression of CFTR mRNA CTD PMID:19684285 Cftr Rat 3',5'-cyclic AMP multiple interactions EXP 6480464 CFTR protein promotes the reaction [Cyclic AMP results in increased transport of Chlorine] more ... CTD PMID:12529251 and PMID:12612912 Cftr Rat 3',5'-cyclic AMP increases activity ISO CFTR (Homo sapiens) 6480464 Cyclic AMP results in increased activity of CFTR protein CTD PMID:15229107 and PMID:15371258 Cftr Rat 3',5'-cyclic AMP multiple interactions ISO Cftr (Mus musculus) 6480464 Genistein promotes the reaction [Cyclic AMP results in increased activity of CFTR protein mutant form] CTD PMID:12556293 Cftr Rat 3',5'-cyclic AMP multiple interactions ISO CFTR (Homo sapiens) 6480464 Cyclic AMP promotes the reaction [CFTR protein results in increased transport of Bicarbonates] and Cyclic AMP promotes the reaction [CFTR protein results in increased transport of Chlorides] CTD PMID:11786964 Cftr Rat 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO CFTR (Homo sapiens) 6480464 1-Methyl-3-isobutylxanthine promotes the reaction [CFTR protein affects the export of Chlorides] more ... CTD PMID:12914781 more ... Cftr Rat 3-isobutyl-1-methyl-7H-xanthine multiple interactions EXP 6480464 1-Methyl-3-isobutylxanthine promotes the reaction [CFTR protein affects the transport of Water] CTD PMID:12606488 Cftr Rat 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO Cftr (Mus musculus) 6480464 [1-Methyl-3-isobutylxanthine co-treated with Colforsin] results in increased activity of CFTR protein CTD PMID:15517342 Cftr Rat 3-isobutyl-1-methyl-7H-xanthine increases activity ISO CFTR (Homo sapiens) 6480464 1-Methyl-3-isobutylxanthine results in increased activity of CFTR protein CTD PMID:12914781 Cftr Rat 4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid multiple interactions ISO CFTR (Homo sapiens) 6480464 4 more ... CTD PMID:16038730 Cftr Rat 4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid decreases activity ISO CFTR (Homo sapiens) 6480464 4 more ... CTD PMID:15131065 Cftr Rat 4,4'-sulfonyldiphenol increases expression ISO CFTR (Homo sapiens) 6480464 bisphenol S results in increased expression of CFTR mRNA CTD PMID:30616060 Cftr Rat 4,4'-sulfonyldiphenol increases expression ISO Cftr (Mus musculus) 6480464 bisphenol S results in increased expression of CFTR mRNA CTD PMID:30951980 Cftr Rat 4-phenylbutyric acid multiple interactions ISO CFTR (Homo sapiens) 6480464 4-phenylbutyric acid results in increased activity of and affects the localization of CFTR protein mutant form and 4-phenylbutyric acid results in increased stability of and affects the localization of CFTR protein CTD PMID:14583596 and PMID:15880796 Cftr Rat 4-phenylbutyric acid increases activity ISO CFTR (Homo sapiens) 6480464 4-phenylbutyric acid results in increased activity of CFTR protein mutant form CTD PMID:15191910 Cftr Rat 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole affects metabolic processing ISO Cftr (Mus musculus) 6480464 CFTR protein affects the metabolism of Omeprazole CTD PMID:15319328 Cftr Rat 5-Nitro-2-(3-phenylpropylamino)benzoic acid multiple interactions ISO CFTR (Homo sapiens) 6480464 5-nitro-2-(3-phenylpropylamino)benzoic acid analog binds to and results in increased activity of CFTR protein more ... CTD PMID:15857825 Cftr Rat 5-Nitro-2-(3-phenylpropylamino)benzoic acid decreases activity EXP 6480464 5-nitro-2-(3-phenylpropylamino)benzoic acid results in decreased activity of CFTR protein CTD PMID:15389550 Cftr Rat 5-Nitro-2-(3-phenylpropylamino)benzoic acid decreases activity ISO CFTR (Homo sapiens) 6480464 5-nitro-2-(3-phenylpropylamino)benzoic acid results in decreased activity of CFTR protein CTD PMID:15131065 more ... Cftr Rat 6-propyl-2-thiouracil affects expression EXP 6480464 Propylthiouracil affects the expression of CFTR mRNA CTD PMID:24780913 Cftr Rat 8-(4-chlorophenylthio)-cAMP multiple interactions ISO CFTR (Homo sapiens) 6480464 [1-Methyl-3-isobutylxanthine co-treated with 8-((4-chlorophenyl)thio)cyclic-3' more ... CTD PMID:15163550 Cftr Rat 9-anthroic acid increases activity ISO CFTR (Homo sapiens) 6480464 9-anthroic acid results in increased activity of CFTR protein mutant form CTD PMID:15290302 Cftr Rat 9-anthroic acid decreases activity ISO CFTR (Homo sapiens) 6480464 9-anthroic acid results in decreased activity of CFTR protein CTD PMID:15290302 Cftr Rat acetamide increases expression EXP 6480464 acetamide results in increased expression of CFTR mRNA CTD PMID:31881176 Cftr Rat acivicin multiple interactions ISO CFTR (Homo sapiens) 6480464 acivicin inhibits the reaction [S-Nitrosoglutathione results in increased expression of and results in increased stability of CFTR protein] and acivicin inhibits the reaction [S-Nitrosoglutathione results in increased expression of CFTR mRNA] CTD PMID:14766015 Cftr Rat adenosine increases activity ISO CFTR (Homo sapiens) 6480464 Adenosine results in increased activity of CFTR protein CTD PMID:15039139 Cftr Rat adenosine multiple interactions ISO CFTR (Homo sapiens) 6480464 [Isoproterenol co-treated with Adenosine] results in increased activity of CFTR protein CTD PMID:15039139 Cftr Rat ADP multiple interactions ISO CFTR (Homo sapiens) 6480464 Adenosine Diphosphate binds to and results in decreased activity of CFTR protein more ... CTD PMID:15684079 Cftr Rat aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of CFTR mRNA CTD PMID:23630614 more ... Cftr Rat AICA ribonucleotide multiple interactions EXP 6480464 AICA ribonucleotide inhibits the reaction [Colforsin results in increased activity of CFTR protein] CTD PMID:12519745 Cftr Rat all-trans-retinoic acid decreases expression ISO Cftr (Mus musculus) 6480464 Tretinoin results in decreased expression of CFTR mRNA CTD PMID:12834868 Cftr Rat allethrin multiple interactions EXP 6480464 [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of CFTR protein CTD PMID:34896426 Cftr Rat amiloride increases activity ISO Cftr (Mus musculus) 6480464 Amiloride results in increased activity of CFTR protein CTD PMID:15246976 Cftr Rat amiloride increases activity EXP 126928119 Amiloride increases activity of Cftr protein in nasal cavity epithelium RGD Cftr Rat aminoguanidine multiple interactions ISO CFTR (Homo sapiens) 6480464 pimagedine inhibits the reaction [Ozone results in decreased expression of CFTR mRNA] and pimagedine inhibits the reaction [Ozone results in decreased expression of CFTR protein] CTD PMID:19061877 Cftr Rat ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of CFTR mRNA CTD PMID:16483693 Cftr Rat AMP-PNP affects activity ISO CFTR (Homo sapiens) 6480464 Adenylyl Imidodiphosphate affects the activity of CFTR protein CTD PMID:15657297 Cftr Rat apigenin increases activity ISO CFTR (Homo sapiens) 6480464 Apigenin results in increased activity of CFTR protein and Apigenin results in increased activity of CFTR protein mutant form CTD PMID:15191910 and PMID:15277574 Cftr Rat apigenin affects localization ISO CFTR (Homo sapiens) 6480464 Apigenin affects the localization of CFTR protein mutant form CTD PMID:15191910 Cftr Rat arsane decreases expression ISO CFTR (Homo sapiens) 6480464 Arsenic results in decreased expression of CFTR mRNA CTD PMID:36861143 Cftr Rat arsenic atom decreases expression ISO CFTR (Homo sapiens) 6480464 Arsenic results in decreased expression of CFTR mRNA CTD PMID:36861143 Cftr Rat arsenite(3-) decreases methylation ISO CFTR (Homo sapiens) 6480464 arsenite results in decreased methylation of CFTR promoter CTD PMID:23974009 Cftr Rat ATP multiple interactions ISO CFTR (Homo sapiens) 6480464 3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone inhibits the reaction [Adenosine Triphosphate promotes the reaction [CFTR protein results in increased export of Chlorides]] more ... CTD PMID:14710196 more ... Cftr Rat atrazine affects methylation EXP 6480464 Atrazine affects the methylation of CFTR gene CTD PMID:28931070 Cftr Rat baclofen multiple interactions ISO CFTR (Homo sapiens) 6480464 Baclofen promotes the reaction [Isoproterenol results in increased activity of CFTR protein] CTD PMID:15151902 Cftr Rat baicalein increases activity ISO CFTR (Homo sapiens) 6480464 baicalein results in increased activity of CFTR protein CTD PMID:15234961 Cftr Rat belinostat decreases expression ISO CFTR (Homo sapiens) 6480464 belinostat results in decreased expression of CFTR mRNA CTD PMID:27188386 Cftr Rat benzo[a]pyrene increases methylation ISO CFTR (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of CFTR exon CTD PMID:27901495 Cftr Rat benzo[a]pyrene affects methylation ISO CFTR (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of CFTR promoter CTD PMID:27901495 Cftr Rat bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with Estradiol] results in increased expression of CFTR mRNA and [bisphenol A co-treated with Testosterone] results in decreased expression of CFTR mRNA CTD PMID:26496021 Cftr Rat bisphenol A increases expression ISO Cftr (Mus musculus) 6480464 bisphenol A results in increased expression of CFTR mRNA CTD PMID:32156529 Cftr Rat bisphenol A multiple interactions ISO CFTR (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of CFTR gene CTD PMID:31601247 Cftr Rat bisphenol A increases methylation ISO CFTR (Homo sapiens) 6480464 bisphenol A results in increased methylation of CFTR gene CTD PMID:31601247 Cftr Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of CFTR mRNA CTD PMID:34947998 Cftr Rat bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of CFTR mRNA CTD PMID:25181051 Cftr Rat brefeldin A decreases activity ISO CFTR (Homo sapiens) 6480464 Brefeldin A results in decreased activity of CFTR protein CTD PMID:15371258 Cftr Rat brefeldin A multiple interactions ISO CFTR (Homo sapiens) 6480464 Brefeldin A inhibits the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]] more ... CTD PMID:18230692 Cftr Rat brimonidine tartrate multiple interactions ISO Cftr (Mus musculus) 6480464 Brimonidine Tartrate inhibits the reaction [CFTR protein affects the transport of Chlorides] CTD PMID:12598592 Cftr Rat bumetanide decreases activity ISO CFTR (Homo sapiens) 6480464 Bumetanide results in decreased activity of CFTR protein CTD PMID:15131065 and PMID:15802612 Cftr Rat cadmium atom decreases expression ISO CFTR (Homo sapiens) 6480464 Cadmium results in decreased expression of CFTR mRNA and Cadmium results in decreased expression of CFTR protein CTD PMID:20363832 and PMID:21120746 Cftr Rat cadmium atom decreases expression ISO Cftr (Mus musculus) 6480464 Cadmium results in decreased expression of CFTR protein CTD PMID:20363832 Cftr Rat cadmium atom multiple interactions ISO CFTR (Homo sapiens) 6480464 [Cadmium results in decreased expression of CFTR protein] which results in decreased transport of Chlorides and alpha-Tocopherol inhibits the reaction [Cadmium results in decreased expression of CFTR protein] CTD PMID:20363832 Cftr Rat capsaicin increases activity ISO Cftr (Mus musculus) 6480464 Capsaicin results in increased activity of CFTR protein and Capsaicin results in increased activity of CFTR protein mutant form CTD PMID:15155835 Cftr Rat carbon nanotube increases expression ISO CFTR (Homo sapiens) 6480464 Nanotubes and Carbon results in increased expression of CFTR mRNA CTD PMID:25511174 Cftr Rat CGP 12177 multiple interactions ISO CFTR (Homo sapiens) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [CGP 12177 results in increased activity of CFTR protein] more ... CTD PMID:15563584 Cftr Rat CGP 12177 increases activity ISO CFTR (Homo sapiens) 6480464 CGP 12177 results in increased activity of CFTR protein CTD PMID:15563584 Cftr Rat chelerythrine decreases activity ISO CFTR (Homo sapiens) 6480464 chelerythrine results in decreased activity of CFTR protein CTD PMID:14744818 Cftr Rat chlorothalonil decreases expression ISO Cftr (Mus musculus) 6480464 tetrachloroisophthalonitrile results in decreased expression of CFTR protein CTD PMID:33246813 Cftr Rat chlorothalonil multiple interactions ISO Cftr (Mus musculus) 6480464 [procymidone co-treated with tetrachloroisophthalonitrile] results in decreased expression of CFTR protein and [tetrachloroisophthalonitrile co-treated with procymidone] results in increased expression of CFTR mRNA CTD PMID:33246813 Cftr Rat choline multiple interactions ISO Cftr (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CFTR mRNA CTD PMID:20938992 Cftr Rat chromium(6+) affects expression ISO Cftr (Mus musculus) 6480464 chromium hexavalent ion affects the expression of CFTR mRNA CTD PMID:28472532 Cftr Rat cilostazol multiple interactions ISO CFTR (Homo sapiens) 6480464 cilostazol promotes the reaction [CFTR protein affects the secretion of Chlorides] CTD PMID:12714375 Cftr Rat cilostazol increases activity ISO CFTR (Homo sapiens) 6480464 cilostazol results in increased activity of CFTR protein CTD PMID:12714375 Cftr Rat clobetasol increases expression ISO Cftr (Mus musculus) 6480464 Clobetasol results in increased expression of CFTR mRNA CTD PMID:27462272 Cftr Rat clofibrate increases expression ISO Cftr (Mus musculus) 6480464 Clofibrate results in increased expression of CFTR mRNA CTD PMID:17585979 Cftr Rat clonidine multiple interactions ISO Cftr (Mus musculus) 6480464 Clonidine inhibits the reaction [CFTR protein affects the transport of Chlorides] CTD PMID:12598592 Cftr Rat clonidine (amino form) multiple interactions ISO Cftr (Mus musculus) 6480464 Clonidine inhibits the reaction [CFTR protein affects the transport of Chlorides] CTD PMID:12598592 Cftr Rat clonidine (imino form) multiple interactions ISO Cftr (Mus musculus) 6480464 Clonidine inhibits the reaction [CFTR protein affects the transport of Chlorides] CTD PMID:12598592 Cftr Rat colforsin daropate hydrochloride affects localization ISO CFTR (Homo sapiens) 6480464 Colforsin affects the localization of CFTR protein CTD PMID:15994425 Cftr Rat colforsin daropate hydrochloride multiple interactions ISO Cftr (Mus musculus) 6480464 [1-Methyl-3-isobutylxanthine co-treated with Colforsin] results in increased activity of CFTR protein and Colforsin promotes the reaction [Nimodipine results in increased activity of CFTR protein] CTD PMID:15517342 and PMID:33872679 Cftr Rat colforsin daropate hydrochloride multiple interactions ISO CFTR (Homo sapiens) 6480464 3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone inhibits the reaction [[[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides] more ... CTD PMID:12914781 more ... Cftr Rat colforsin daropate hydrochloride increases activity ISO Cftr (Mus musculus) 6480464 Colforsin results in increased activity of CFTR protein CTD PMID:15246976 more ... Cftr Rat colforsin daropate hydrochloride multiple interactions EXP 6480464 [Colforsin co-treated with Genistein] results in increased activity of CFTR protein and AICA ribonucleotide inhibits the reaction [Colforsin results in increased activity of CFTR protein] CTD PMID:12519745 and PMID:17596272 Cftr Rat colforsin daropate hydrochloride increases activity ISO CFTR (Homo sapiens) 6480464 Colforsin analog results in increased activity of CFTR protein mutant form more ... CTD PMID:12914781 more ... Cftr Rat colforsin daropate hydrochloride increases activity EXP 6480464 Colforsin results in increased activity of CFTR protein CTD PMID:12519745 and PMID:15389550 Cftr Rat Cuprizon decreases expression EXP 6480464 Cuprizone results in decreased expression of CFTR mRNA CTD PMID:26577399 Cftr Rat curcumin multiple interactions ISO CFTR (Homo sapiens) 6480464 [PRKCA protein results in increased phosphorylation of CFTR protein] promotes the reaction [Curcumin results in increased activity of CFTR protein] more ... CTD PMID:17178710 and PMID:23978416 Cftr Rat curcumin increases activity ISO CFTR (Homo sapiens) 6480464 Curcumin results in increased activity of CFTR protein and Curcumin results in increased activity of CFTR protein mutant form CTD PMID:15582996 and PMID:17178710 Cftr Rat curcumin affects localization ISO Cftr (Mus musculus) 6480464 Curcumin affects the localization of CFTR protein mutant form CTD PMID:15105504 Cftr Rat curcumin multiple interactions ISO Cftr (Mus musculus) 6480464 Curcumin affects the folding of and affects the localization of CFTR protein mutant form CTD PMID:15280357 Cftr Rat cycloheximide affects expression EXP 6480464 Cycloheximide affects the expression of CFTR mRNA CTD PMID:17290305 Cftr Rat cyclosporin A decreases methylation ISO CFTR (Homo sapiens) 6480464 Cyclosporine results in decreased methylation of CFTR promoter CTD PMID:27989131 Cftr Rat cyhalothrin multiple interactions EXP 6480464 [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of CFTR protein CTD PMID:34896426 Cftr Rat cypermethrin multiple interactions EXP 6480464 [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of CFTR protein CTD PMID:34896426 Cftr Rat DDT multiple interactions ISO CFTR (Homo sapiens) 6480464 DDT inhibits the reaction [S-Nitrosoglutathione results in increased expression of and results in increased stability of CFTR protein] CTD PMID:14766015 Cftr Rat decan-1-ol increases activity ISO CFTR (Homo sapiens) 6480464 n-decyl alcohol results in increased activity of CFTR protein CTD PMID:14967738 Cftr Rat desmopressin increases activity ISO CFTR (Homo sapiens) 6480464 Deamino Arginine Vasopressin results in increased activity of CFTR protein CTD PMID:15685210 Cftr Rat dextran sulfate multiple interactions ISO Cftr (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CFTR mRNA CTD PMID:29950665 Cftr Rat dibromine decreases activity ISO CFTR (Homo sapiens) 6480464 Bromine results in decreased activity of CFTR protein CTD PMID:15286085 Cftr Rat dichlorine multiple interactions EXP 6480464 CFTR protein promotes the reaction [Cyclic AMP results in increased transport of Chlorine] and Nitric Oxide inhibits the reaction [CFTR protein promotes the reaction [Cyclic AMP results in increased transport of Chlorine]] CTD PMID:12612912 Cftr Rat dichlorine increases transport ISO CFTR (Homo sapiens) 6480464 CFTR protein results in increased transport of Chlorine CTD PMID:21765217 Cftr Rat diethylstilbestrol decreases activity ISO Cftr (Mus musculus) 6480464 Diethylstilbestrol results in decreased activity of CFTR protein CTD PMID:10991979 Cftr Rat diethylstilbestrol increases expression ISO Cftr (Mus musculus) 6480464 Diethylstilbestrol results in increased expression of CFTR mRNA CTD PMID:15289156 Cftr Rat diprotium oxide multiple interactions EXP 6480464 1-Methyl-3-isobutylxanthine promotes the reaction [CFTR protein affects the transport of Water] more ... CTD PMID:12606488 Cftr Rat dorsomorphin multiple interactions ISO CFTR (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 Cftr Rat doxorubicin increases folding ISO CFTR (Homo sapiens) 6480464 Doxorubicin results in increased folding of CFTR protein mutant form CTD PMID:17762173 Cftr Rat doxorubicin decreases ubiquitination ISO CFTR (Homo sapiens) 6480464 Doxorubicin results in decreased ubiquitination of CFTR protein mutant form CTD PMID:17762173 Cftr Rat enilconazole affects binding ISO Cftr (Mus musculus) 6480464 enilconazole binds to CFTR protein CTD PMID:29106682 Cftr Rat enilconazole decreases expression ISO Cftr (Mus musculus) 6480464 enilconazole results in decreased expression of CFTR mRNA and enilconazole results in decreased expression of CFTR protein CTD PMID:29106682 and PMID:32814239 Cftr Rat ethanol multiple interactions ISO Cftr (Mus musculus) 6480464 [Carbon Tetrachloride co-treated with Ethanol] results in increased expression of CFTR mRNA CTD PMID:30517762 Cftr Rat fenamic acid decreases activity EXP 6480464 fenamic acid results in decreased activity of CFTR protein CTD PMID:15020588 Cftr Rat fenamic acid decreases activity ISO CFTR (Homo sapiens) 6480464 fenamic acid results in decreased activity of CFTR protein CTD PMID:14502435 more ... Cftr Rat fenamic acid multiple interactions ISO CFTR (Homo sapiens) 6480464 fenamic acid inhibits the reaction [[[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides] and fenamic acid inhibits the reaction [Colforsin results in increased activity of CFTR protein] CTD PMID:16038730 and PMID:18230692 Cftr Rat fenamic acid decreases activity ISO Cftr (Mus musculus) 6480464 fenamic acid results in decreased activity of CFTR protein CTD PMID:15986093 Cftr Rat fenvalerate multiple interactions EXP 6480464 [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of CFTR protein CTD PMID:34896426 Cftr Rat flufenamic acid decreases activity ISO CFTR (Homo sapiens) 6480464 Flufenamic Acid results in decreased activity of CFTR protein CTD PMID:15277574 Cftr Rat folic acid multiple interactions ISO Cftr (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CFTR mRNA CTD PMID:20938992 Cftr Rat fulvestrant multiple interactions ISO CFTR (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of CFTR gene CTD PMID:31601247 Cftr Rat furan increases expression EXP 6480464 furan results in increased expression of CFTR mRNA CTD PMID:26194646 and PMID:27387713 Cftr Rat geldanamycin multiple interactions ISO CFTR (Homo sapiens) 6480464 geldanamycin promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]] more ... CTD PMID:18230692 Cftr Rat gemfibrozil decreases activity ISO Cftr (Mus musculus) 6480464 Gemfibrozil results in decreased activity of CFTR protein CTD PMID:15289377 Cftr Rat geneticin increases expression ISO CFTR (Homo sapiens) 6480464 antibiotic G 418 results in increased expression of CFTR protein mutant form CTD PMID:17541014 Cftr Rat genistein affects localization ISO CFTR (Homo sapiens) 6480464 Genistein affects the localization of CFTR protein mutant form CTD PMID:15191910 Cftr Rat genistein increases activity ISO CFTR (Homo sapiens) 6480464 Genistein results in increased activity of CFTR protein and Genistein results in increased activity of CFTR protein mutant form CTD PMID:12914781 more ... Cftr Rat genistein increases expression ISO Cftr (Mus musculus) 6480464 Genistein results in increased expression of CFTR mRNA CTD PMID:15289156 Cftr Rat genistein multiple interactions EXP 6480464 [Colforsin co-treated with Genistein] results in increased activity of CFTR protein more ... CTD PMID:17596272 and PMID:26529183 Cftr Rat genistein increases activity ISO Cftr (Mus musculus) 6480464 Genistein results in increased activity of CFTR protein and Genistein results in increased activity of CFTR protein mutant form CTD PMID:15155835 Cftr Rat genistein multiple interactions ISO Cftr (Mus musculus) 6480464 Genistein promotes the reaction [Cyclic AMP results in increased activity of CFTR protein mutant form] CTD PMID:12556293 Cftr Rat genistein multiple interactions ISO CFTR (Homo sapiens) 6480464 3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone inhibits the reaction [[[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides] more ... CTD PMID:12914781 and PMID:18230692 Cftr Rat gentamycin multiple interactions ISO CFTR (Homo sapiens) 6480464 Gentamicins results in increased expression of and results in increased activity of CFTR protein mutant form CTD PMID:11401894 Cftr Rat gentamycin multiple interactions EXP 6480464 [Gentamicins results in increased expression of and results in increased activity of CFTR protein mutant form] which results in increased export of Chlorides and Gentamicins results in increased expression of and results in increased activity of CFTR protein mutant form CTD PMID:17290305 Cftr Rat gentamycin increases activity ISO CFTR (Homo sapiens) 6480464 Gentamicins results in increased activity of CFTR protein mutant form CTD PMID:11786964 and PMID:14534336 Cftr Rat glufosinate decreases expression ISO Cftr (Mus musculus) 6480464 phosphinothricin results in decreased expression of CFTR mRNA CTD PMID:34597628 Cftr Rat glutathione multiple interactions ISO CFTR (Homo sapiens) 6480464 [Bicarbonates co-treated with Glutathione co-treated with Ascorbic Acid] results in increased activity of CFTR protein more ... CTD PMID:15657297 more ... Cftr Rat glutathione affects export ISO Cftr (Mus musculus) 6480464 CFTR protein affects the export of Glutathione CTD PMID:15561710 Cftr Rat glutathione decreases activity ISO CFTR (Homo sapiens) 6480464 Glutathione analog results in decreased activity of CFTR protein CTD PMID:15657297 Cftr Rat glutathione disulfide decreases activity ISO CFTR (Homo sapiens) 6480464 Glutathione Disulfide results in decreased activity of CFTR protein CTD PMID:15657297 Cftr Rat glyburide multiple interactions EXP 6480464 Glyburide inhibits the reaction [[Phenylephrine co-treated with 5-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride] results in increased activity of CFTR protein] CTD PMID:17596272 Cftr Rat glyburide decreases activity EXP 6480464 Glyburide results in decreased activity of CFTR protein CTD PMID:15236628 more ... Cftr Rat glyburide decreases activity ISO CFTR (Homo sapiens) 6480464 Glyburide results in decreased activity of CFTR protein CTD PMID:14502435 more ... Cftr Rat glyburide decreases activity ISO Cftr (Mus musculus) 6480464 Glyburide results in decreased activity of CFTR protein CTD PMID:15650130 and PMID:16012949 Cftr Rat glyburide multiple interactions ISO Cftr (Mus musculus) 6480464 Glyburide inhibits the reaction [CFTR protein affects the transport of Bicarbonates] and Glyburide inhibits the reaction [CFTR protein affects the transport of Chlorides] CTD PMID:15650130 Cftr Rat glyburide multiple interactions ISO CFTR (Homo sapiens) 6480464 Glyburide binds to and results in decreased activity of CFTR protein more ... CTD PMID:14967738 more ... Cftr Rat glycidol decreases expression EXP 6480464 glycidol results in decreased expression of CFTR mRNA CTD PMID:24915197 Cftr Rat Guanylin increases phosphorylation EXP 6480464 guanylin results in increased phosphorylation of CFTR protein CTD PMID:14986129 Cftr Rat gusperimus multiple interactions ISO CFTR (Homo sapiens) 6480464 [ALB protein binds to gusperimus] which results in increased activity of CFTR protein mutant form CTD PMID:18515409 Cftr Rat heptan-1-ol increases activity ISO CFTR (Homo sapiens) 6480464 Heptanol results in increased activity of CFTR protein CTD PMID:14967738 Cftr Rat hyaluronic acid increases export ISO CFTR (Homo sapiens) 6480464 CFTR protein results in increased export of Hyaluronic Acid CTD PMID:23978416 Cftr Rat hyaluronic acid multiple interactions ISO CFTR (Homo sapiens) 6480464 Curcumin analog inhibits the reaction [CFTR protein results in increased export of Hyaluronic Acid] and xanthohumol inhibits the reaction [CFTR protein results in increased export of Hyaluronic Acid] CTD PMID:23978416 Cftr Rat hydrogen peroxide affects expression ISO CFTR (Homo sapiens) 6480464 Hydrogen Peroxide affects the expression of CFTR mRNA CTD PMID:20044591 Cftr Rat hydrogencarbonate increases transport ISO CFTR (Homo sapiens) 6480464 CFTR protein results in increased transport of Bicarbonates CTD PMID:11786964 Cftr Rat hydrogencarbonate decreases secretion ISO Cftr (Mus musculus) 6480464 CFTR protein mutant form results in decreased secretion of Bicarbonates CTD PMID:15480994 Cftr Rat hydrogencarbonate decreases transport ISO Cftr (Mus musculus) 6480464 CFTR protein mutant form results in decreased transport of Bicarbonates CTD PMID:15650130 Cftr Rat hydrogencarbonate multiple interactions ISO Cftr (Mus musculus) 6480464 Glyburide inhibits the reaction [CFTR protein affects the transport of Bicarbonates] CTD PMID:15650130 Cftr Rat hydrogencarbonate multiple interactions ISO CFTR (Homo sapiens) 6480464 [Bicarbonates co-treated with Glutathione co-treated with Ascorbic Acid] results in increased activity of CFTR protein and Cyclic AMP promotes the reaction [CFTR protein results in increased transport of Bicarbonates] CTD PMID:11786964 and PMID:32374624 Cftr Rat hydrogencarbonate affects transport ISO Cftr (Mus musculus) 6480464 CFTR protein affects the transport of Bicarbonates CTD PMID:14679199 and PMID:15650130 Cftr Rat hydrogencarbonate decreases activity ISO CFTR (Homo sapiens) 6480464 Bicarbonates results in decreased activity of CFTR protein CTD PMID:15286085 Cftr Rat hydrogencarbonate decreases transport ISO CFTR (Homo sapiens) 6480464 CFTR protein mutant form results in decreased transport of Bicarbonates CTD PMID:11786964 Cftr Rat inulin multiple interactions ISO Cftr (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of CFTR mRNA CTD PMID:36331819 Cftr Rat iodide salt multiple interactions ISO CFTR (Homo sapiens) 6480464 3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone inhibits the reaction [[[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides] more ... CTD PMID:18230692 and PMID:18297105 Cftr Rat ionomycin increases activity EXP 6480464 Ionomycin results in increased activity of CFTR protein CTD PMID:15389550 Cftr Rat irinotecan affects expression EXP 6480464 Irinotecan affects the expression of CFTR mRNA CTD PMID:20097248 Cftr Rat iron(III) citrate decreases expression ISO CFTR (Homo sapiens) 6480464 ferric citrate results in decreased expression of CFTR mRNA CTD PMID:29959986 Cftr Rat isoprenaline multiple interactions ISO CFTR (Homo sapiens) 6480464 [Isoproterenol co-treated with Adenosine] results in increased activity of CFTR protein more ... CTD PMID:15039139 and PMID:15151902 Cftr Rat isoprenaline increases activity ISO CFTR (Homo sapiens) 6480464 Isoproterenol results in increased activity of CFTR protein CTD PMID:15039139 and PMID:15151902 Cftr Rat isoprenaline increases activity EXP 6480464 Isoproterenol results in increased activity of CFTR protein CTD PMID:15020588 Cftr Rat isotocin increases activity ISO CFTR (Homo sapiens) 6480464 isotocin results in increased activity of CFTR protein CTD PMID:15685210 Cftr Rat ivacaftor multiple interactions ISO CFTR (Homo sapiens) 6480464 [ivacaftor co-treated with Colforsin co-treated with lumacaftor] results in increased activity of CFTR protein mutant form more ... CTD PMID:19846789 more ... Cftr Rat ivacaftor increases activity ISO CFTR (Homo sapiens) 6480464 ivacaftor results in increased activity of CFTR protein and ivacaftor results in increased activity of CFTR protein mutant form CTD PMID:19846789 more ... Cftr Rat kaempferol affects localization ISO CFTR (Homo sapiens) 6480464 kaempferol affects the localization of CFTR protein mutant form CTD PMID:15191910 Cftr Rat L-1,4-dithiothreitol multiple interactions ISO CFTR (Homo sapiens) 6480464 Dithiothreitol inhibits the reaction [Glutathione results in decreased activity of CFTR protein] CTD PMID:15657297 Cftr Rat L-ascorbic acid multiple interactions ISO CFTR (Homo sapiens) 6480464 [Bicarbonates co-treated with Glutathione co-treated with Ascorbic Acid] results in increased activity of CFTR protein more ... CTD PMID:14993613 more ... Cftr Rat L-ascorbic acid increases activity ISO CFTR (Homo sapiens) 6480464 Ascorbic Acid results in increased activity of CFTR protein CTD PMID:14993613 and PMID:32374624 Cftr Rat L-methionine multiple interactions ISO Cftr (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CFTR mRNA CTD PMID:20938992 Cftr Rat lithium chloride increases expression ISO CFTR (Homo sapiens) 6480464 Lithium Chloride results in increased expression of CFTR mRNA CTD PMID:23527032 Cftr Rat lonidamine decreases activity ISO CFTR (Homo sapiens) 6480464 lonidamine results in decreased activity of CFTR protein CTD PMID:15634668 Cftr Rat lonidamine multiple interactions EXP 6480464 lonidamine inhibits the reaction [CFTR protein promotes the reaction [AQP9 protein affects the transport of Water]] CTD PMID:12606488 Cftr Rat lumacaftor multiple interactions ISO CFTR (Homo sapiens) 6480464 [Colforsin co-treated with lumacaftor] results in increased activity of CFTR protein mutant form more ... CTD PMID:31324722 and PMID:32374624 Cftr Rat lumacaftor affects folding ISO CFTR (Homo sapiens) 6480464 lumacaftor affects the folding of CFTR protein mutant form CTD PMID:32374624 Cftr Rat LY294002 multiple interactions ISO CFTR (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [CGP 12177 results in increased activity of CFTR protein] CTD PMID:15563584 Cftr Rat manganese(II) chloride increases expression EXP 6480464 manganese chloride results in increased expression of CFTR mRNA CTD PMID:28801915 Cftr Rat medetomidine multiple interactions ISO Cftr (Mus musculus) 6480464 Medetomidine inhibits the reaction [CFTR protein affects the transport of Chlorides] CTD PMID:12598592 Cftr Rat mercury dibromide increases expression ISO CFTR (Homo sapiens) 6480464 mercuric bromide results in increased expression of CFTR mRNA CTD PMID:26272509 Cftr Rat mercury dibromide multiple interactions ISO CFTR (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CFTR mRNA CTD PMID:27188386 Cftr Rat methacholine chloride multiple interactions ISO CFTR (Homo sapiens) 6480464 3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone inhibits the reaction [Methacholine Chloride promotes the reaction [CFTR protein results in increased export of Chlorides]] and Methacholine Chloride promotes the reaction [CFTR protein results in increased export of Chlorides] CTD PMID:20675434 Cftr Rat miglustat increases activity ISO CFTR (Homo sapiens) 6480464 miglustat results in increased activity of CFTR protein mutant form CTD PMID:18230692 Cftr Rat miglustat multiple interactions ISO CFTR (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]] more ... CTD PMID:18230692 Cftr Rat milrinone multiple interactions ISO CFTR (Homo sapiens) 6480464 Milrinone promotes the reaction [CFTR protein affects the secretion of Chlorides] CTD PMID:12714375 Cftr Rat milrinone increases activity ISO CFTR (Homo sapiens) 6480464 Milrinone results in increased activity of CFTR protein CTD PMID:12714375 Cftr Rat N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide multiple interactions ISO CFTR (Homo sapiens) 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [1-Octanol results in increased activity of CFTR protein] more ... CTD PMID:14967738 more ... Cftr Rat N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide affects localization ISO CFTR (Homo sapiens) 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide affects the localization of CFTR protein CTD PMID:15994425 Cftr Rat N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide decreases activity ISO CFTR (Homo sapiens) 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased activity of CFTR protein CTD PMID:14744818 Cftr Rat N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide multiple interactions EXP 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [CFTR protein affects the transport of Water] CTD PMID:12606488 Cftr Rat N-acetyl-L-cysteine multiple interactions ISO CFTR (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [Ozone results in decreased expression of CFTR mRNA] and Acetylcysteine inhibits the reaction [Ozone results in decreased expression of CFTR protein] CTD PMID:19061877 Cftr Rat N-Acetylleucyl-leucyl-methioninal multiple interactions ISO CFTR (Homo sapiens) 6480464 calpain inhibitor 2 promotes the reaction [lumacaftor binds to and affects the folding of CFTR protein mutant form] CTD PMID:31324722 Cftr Rat N-acetylsphingosine increases activity ISO CFTR (Homo sapiens) 6480464 N-acetylsphingosine results in increased activity of CFTR protein CTD PMID:15474513 Cftr Rat N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO CFTR (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]] more ... CTD PMID:18230692 Cftr Rat N-ethylmaleimide multiple interactions ISO CFTR (Homo sapiens) 6480464 Ethylmaleimide inhibits the reaction [Glutathione results in decreased activity of CFTR protein] CTD PMID:15657297 Cftr Rat naphthalene multiple interactions ISO Cftr (Mus musculus) 6480464 [naphthalene co-treated with CFTR gene mutant form] results in decreased expression of ACO2 protein more ... CTD PMID:19438287 Cftr Rat naringin multiple interactions ISO Cftr (Mus musculus) 6480464 naringin inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in decreased expression of CFTR mRNA] and naringin inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in decreased expression of CFTR protein] CTD PMID:31301536 Cftr Rat nickel atom decreases expression ISO CFTR (Homo sapiens) 6480464 Nickel results in decreased expression of CFTR mRNA CTD PMID:24768652 and PMID:25583101 Cftr Rat Niflumic acid decreases activity ISO CFTR (Homo sapiens) 6480464 Niflumic Acid results in decreased activity of CFTR protein CTD PMID:14668136 Cftr Rat nimodipine multiple interactions ISO CFTR (Homo sapiens) 6480464 3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone inhibits the reaction [Nimodipine results in increased activity of CFTR protein] and Colforsin promotes the reaction [Nimodipine results in increased activity of CFTR protein] CTD PMID:33872679 Cftr Rat nimodipine increases activity ISO CFTR (Homo sapiens) 6480464 Nimodipine results in increased activity of CFTR protein CTD PMID:33872679 Cftr Rat nimodipine multiple interactions ISO Cftr (Mus musculus) 6480464 3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone inhibits the reaction [Nimodipine results in increased activity of CFTR protein] and Colforsin promotes the reaction [Nimodipine results in increased activity of CFTR protein] CTD PMID:33872679 Cftr Rat nitrates decreases activity ISO CFTR (Homo sapiens) 6480464 Nitrates results in decreased activity of CFTR protein CTD PMID:15286085 Cftr Rat nitric oxide multiple interactions EXP 6480464 Nitric Oxide inhibits the reaction [CFTR protein promotes the reaction [Cyclic AMP results in increased transport of Chlorine]] CTD PMID:12612912 Cftr Rat nocodazole affects localization ISO CFTR (Homo sapiens) 6480464 Nocodazole affects the localization of CFTR protein CTD PMID:15994425 Cftr Rat nocodazole multiple interactions EXP 6480464 Nocodazole inhibits the reaction [Cyclic AMP affects the localization of and results in increased activity of CFTR protein] CTD PMID:12529251 Cftr Rat octan-1-ol increases activity ISO CFTR (Homo sapiens) 6480464 1-Octanol results in increased activity of CFTR protein and 1-Octanol results in increased activity of CFTR protein mutant form CTD PMID:14967738 Cftr Rat octan-1-ol multiple interactions ISO CFTR (Homo sapiens) 6480464 Glyburide inhibits the reaction [1-Octanol results in increased activity of CFTR protein] and N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [1-Octanol results in increased activity of CFTR protein] CTD PMID:14967738 Cftr Rat octan-2-ol increases activity ISO CFTR (Homo sapiens) 6480464 2-octanol results in increased activity of CFTR protein CTD PMID:14967738 Cftr Rat okadaic acid decreases activity ISO CFTR (Homo sapiens) 6480464 Okadaic Acid results in decreased activity of CFTR protein CTD PMID:15936019 Cftr Rat omeprazole affects metabolic processing ISO Cftr (Mus musculus) 6480464 CFTR protein affects the metabolism of Omeprazole CTD PMID:15319328 Cftr Rat osimertinib multiple interactions ISO CFTR (Homo sapiens) 6480464 osimertinib inhibits the reaction [Dronabinol results in decreased expression of and results in decreased activity of CFTR protein] CTD PMID:29928919 Cftr Rat ozone multiple interactions ISO CFTR (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [Ozone results in decreased expression of CFTR mRNA] more ... CTD PMID:19061877 Cftr Rat ozone multiple interactions ISO Cftr (Mus musculus) 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of CFTR mRNA CTD PMID:34911549 Cftr Rat ozone increases expression ISO CFTR (Homo sapiens) 6480464 Ozone results in increased expression of CFTR mRNA CTD PMID:27206323 Cftr Rat ozone decreases expression ISO CFTR (Homo sapiens) 6480464 Ozone results in decreased expression of CFTR mRNA and Ozone results in decreased expression of CFTR protein CTD PMID:19061877 Cftr Rat P(1),P(5)-bis(5'-adenosyl) pentaphosphate multiple interactions ISO CFTR (Homo sapiens) 6480464 P(1) and P(5)-di(adenosine-5'-)pentaphosphate inhibits the reaction [Adenosine Diphosphate binds to and results in decreased activity of CFTR protein] CTD PMID:15684079 Cftr Rat p-chloromercuribenzoic acid increases expression ISO CFTR (Homo sapiens) 6480464 p-Chloromercuribenzoic Acid results in increased expression of CFTR mRNA CTD PMID:26272509 Cftr Rat p-chloromercuribenzoic acid multiple interactions ISO CFTR (Homo sapiens) 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CFTR mRNA CTD PMID:27188386 Cftr Rat PAPA NONOate affects localization ISO CFTR (Homo sapiens) 6480464 PAPA NONOate affects the localization of CFTR protein CTD PMID:15994425 Cftr Rat papaverine multiple interactions ISO CFTR (Homo sapiens) 6480464 Papaverine promotes the reaction [CFTR protein affects the secretion of Chlorides] CTD PMID:12714375 Cftr Rat papaverine increases activity ISO CFTR (Homo sapiens) 6480464 Papaverine results in increased activity of CFTR protein CTD PMID:12714375 Cftr Rat paraquat affects expression EXP 6480464 Paraquat affects the expression of CFTR mRNA CTD PMID:15206577 Cftr Rat paraquat decreases expression EXP 6480464 Paraquat results in decreased expression of CFTR mRNA CTD PMID:32680482 Cftr Rat paraquat affects splicing ISO Cftr (Mus musculus) 6480464 Paraquat affects the splicing of CFTR exon CTD PMID:27111068 Cftr Rat perfluorooctane-1-sulfonic acid multiple interactions ISO Cftr (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of CFTR mRNA CTD PMID:36331819 Cftr Rat perfluorooctanoic acid increases expression ISO Cftr (Mus musculus) 6480464 perfluorooctanoic acid results in increased expression of CFTR protein CTD PMID:36214631 and PMID:37422089 Cftr Rat phenylephrine multiple interactions EXP 6480464 [Phenylephrine co-treated with 5-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride] results in increased activity of CFTR protein more ... CTD PMID:17596272 Cftr Rat phenylmercury acetate increases expression ISO CFTR (Homo sapiens) 6480464 Phenylmercuric Acetate results in increased expression of CFTR mRNA CTD PMID:26272509 Cftr Rat phenylmercury acetate multiple interactions ISO CFTR (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CFTR mRNA CTD PMID:27188386 Cftr Rat phloretin multiple interactions EXP 6480464 Phloretin inhibits the reaction [CFTR protein promotes the reaction [AQP9 protein affects the transport of Water]] CTD PMID:12606488 Cftr Rat phosphoramide mustard increases expression EXP 6480464 phosphoramide mustard results in increased expression of CFTR mRNA CTD PMID:27888070 Cftr Rat primaquine multiple interactions EXP 6480464 Primaquine inhibits the reaction [Cyclic AMP affects the localization of and results in increased activity of CFTR protein] CTD PMID:12529251 Cftr Rat procymidone multiple interactions ISO Cftr (Mus musculus) 6480464 [procymidone co-treated with tetrachloroisophthalonitrile] results in decreased expression of CFTR protein and [tetrachloroisophthalonitrile co-treated with procymidone] results in increased expression of CFTR mRNA CTD PMID:33246813 Cftr Rat procymidone affects expression ISO Cftr (Mus musculus) 6480464 procymidone affects the expression of CFTR mRNA CTD PMID:36764477 Cftr Rat procymidone increases expression ISO Cftr (Mus musculus) 6480464 procymidone results in increased expression of CFTR mRNA CTD PMID:33246813 Cftr Rat procymidone decreases expression ISO Cftr (Mus musculus) 6480464 procymidone results in decreased expression of CFTR protein CTD PMID:33246813 Cftr Rat progesterone multiple interactions ISO CFTR (Homo sapiens) 6480464 [Progesterone co-treated with Estradiol] results in decreased expression of CFTR mRNA CTD PMID:17404688 Cftr Rat progesterone multiple interactions EXP 6480464 [Genistein co-treated with estradiol-17-benzoate co-treated with Progesterone] results in increased expression of CFTR mRNA and [Genistein co-treated with estradiol-17-benzoate co-treated with Progesterone] results in increased expression of CFTR protein CTD PMID:26529183 Cftr Rat progesterone decreases expression ISO CFTR (Homo sapiens) 6480464 Progesterone results in decreased expression of CFTR mRNA and Progesterone results in decreased expression of CFTR protein CTD PMID:15471937 Cftr Rat prothioconazole increases expression ISO Cftr (Mus musculus) 6480464 prothioconazole results in increased expression of CFTR mRNA CTD PMID:36007749 Cftr Rat pyrethrins decreases expression EXP 6480464 Pyrethrins results in decreased expression of CFTR protein CTD PMID:34896426 Cftr Rat quercetin increases activity ISO CFTR (Homo sapiens) 6480464 Quercetin results in increased activity of CFTR protein mutant form CTD PMID:15191910 Cftr Rat quercetin increases expression EXP 6480464 Quercetin results in increased expression of CFTR mRNA and Quercetin results in increased expression of CFTR protein CTD PMID:28431985 Cftr Rat resveratrol increases activity ISO Cftr (Mus musculus) 6480464 resveratrol results in increased activity of CFTR protein CTD PMID:24282612 Cftr Rat resveratrol multiple interactions ISO CFTR (Homo sapiens) 6480464 [Plant Extracts co-treated with Resveratrol] results in decreased expression of CFTR mRNA CTD PMID:23557933 Cftr Rat resveratrol increases activity ISO CFTR (Homo sapiens) 6480464 resveratrol results in increased activity of CFTR protein CTD PMID:24282612 and PMID:25946147 Cftr Rat roflumilast multiple interactions ISO Cftr (Mus musculus) 6480464 Roflumilast inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in decreased expression of CFTR mRNA] and Roflumilast inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in decreased expression of CFTR protein] CTD PMID:31301536 Cftr Rat roflumilast multiple interactions ISO CFTR (Homo sapiens) 6480464 Roflumilast inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in decreased expression of CFTR mRNA] and Roflumilast inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in decreased expression of CFTR protein] CTD PMID:31301536 Cftr Rat rolipram multiple interactions ISO CFTR (Homo sapiens) 6480464 Rolipram promotes the reaction [CFTR protein affects the secretion of Chlorides] CTD PMID:12714375 Cftr Rat rolipram increases activity ISO CFTR (Homo sapiens) 6480464 Rolipram results in increased activity of CFTR protein CTD PMID:12714375 Cftr Rat rolipram decreases activity ISO CFTR (Homo sapiens) 6480464 Rolipram results in decreased activity of CFTR protein CTD PMID:15611099 Cftr Rat S-nitrosoglutathione multiple interactions ISO CFTR (Homo sapiens) 6480464 acivicin inhibits the reaction [S-Nitrosoglutathione results in increased expression of and results in increased stability of CFTR protein] more ... CTD PMID:14766015 Cftr Rat S-nitrosoglutathione increases expression ISO CFTR (Homo sapiens) 6480464 S-Nitrosoglutathione results in increased expression of CFTR mRNA CTD PMID:14766015 Cftr Rat S-nitrosoglutathione decreases expression ISO CFTR (Homo sapiens) 6480464 S-Nitrosoglutathione results in decreased expression of CFTR mRNA CTD PMID:14766015 Cftr Rat S-nitrosoglutathione decreases activity ISO CFTR (Homo sapiens) 6480464 S-Nitrosoglutathione results in decreased activity of CFTR protein CTD PMID:15657297 Cftr Rat Salmeterol xinafoate increases expression ISO CFTR (Homo sapiens) 6480464 Salmeterol Xinafoate results in increased expression of CFTR protein CTD PMID:12621035 Cftr Rat Salmeterol xinafoate multiple interactions ISO CFTR (Homo sapiens) 6480464 [Salmeterol Xinafoate binds to ADRB2 protein] which results in increased expression of CFTR protein and Salmeterol Xinafoate promotes the reaction [CFTR protein binds to NHERF1 protein] CTD PMID:12621035 Cftr Rat SB 431542 multiple interactions ISO CFTR (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 Cftr Rat serotonin multiple interactions ISO CFTR (Homo sapiens) 6480464 Serotonin promotes the reaction [Isoproterenol results in increased activity of CFTR protein] CTD PMID:15151902 Cftr Rat serotonin increases activity ISO CFTR (Homo sapiens) 6480464 Serotonin results in increased activity of CFTR protein CTD PMID:15151902 Cftr Rat sildenafil citrate affects localization ISO CFTR (Homo sapiens) 6480464 Sildenafil Citrate affects the localization of CFTR protein mutant form CTD PMID:15618584 Cftr Rat sildenafil citrate multiple interactions ISO CFTR (Homo sapiens) 6480464 Sildenafil Citrate promotes the reaction [CFTR protein affects the secretion of Chlorides] CTD PMID:12714375 Cftr Rat sildenafil citrate increases activity ISO CFTR (Homo sapiens) 6480464 Sildenafil Citrate results in increased activity of CFTR protein CTD PMID:12714375 Cftr Rat silicon dioxide decreases expression ISO CFTR (Homo sapiens) 6480464 Silicon Dioxide analog results in decreased expression of CFTR mRNA CTD PMID:25895662 Cftr Rat silicon dioxide decreases expression EXP 6480464 Silicon Dioxide results in decreased expression of CFTR mRNA CTD PMID:32721576 Cftr Rat simvastatin multiple interactions EXP 6480464 Simvastatin inhibits the reaction [lipopolysaccharide more ... CTD PMID:33774062 Cftr Rat sodium arsenite decreases expression ISO CFTR (Homo sapiens) 6480464 sodium arsenite results in decreased expression of CFTR protein CTD PMID:16121039 Cftr Rat sodium arsenite multiple interactions ISO CFTR (Homo sapiens) 6480464 [U 0126 results in decreased activity of MAPK1 protein] inhibits the reaction [sodium arsenite results in decreased expression of CFTR protein] more ... CTD PMID:16121039 Cftr Rat sodium arsenite increases expression ISO CFTR (Homo sapiens) 6480464 sodium arsenite results in increased expression of CFTR mRNA CTD PMID:26535918 Cftr Rat sodium atom multiple interactions ISO CFTR (Homo sapiens) 6480464 [ivacaftor results in increased activity of CFTR protein mutant form] which affects the transport of Sodium CTD PMID:19846789 Cftr Rat sodium iodide affects export ISO CFTR (Homo sapiens) 6480464 CFTR protein affects the export of Sodium Iodide CTD PMID:14502435 Cftr Rat sulforaphane decreases expression ISO Cftr (Mus musculus) 6480464 sulforaphane results in decreased expression of CFTR mRNA CTD PMID:30529165 Cftr Rat tamoxifen affects expression ISO Cftr (Mus musculus) 6480464 Tamoxifen affects the expression of CFTR mRNA CTD PMID:17555576 Cftr Rat taurocholic acid affects uptake ISO Cftr (Mus musculus) 6480464 CFTR protein mutant form affects the uptake of Taurocholic Acid CTD PMID:15099439 Cftr Rat taurocholic acid increases activity ISO Cftr (Mus musculus) 6480464 Taurocholic Acid results in increased activity of CFTR protein CTD PMID:16037545 Cftr Rat taurolithocholic acid sulfate decreases activity ISO CFTR (Homo sapiens) 6480464 taurolithocholic acid 3-sulfate results in decreased activity of CFTR protein CTD PMID:15634668 Cftr Rat testosterone multiple interactions EXP 6480464 [bisphenol A co-treated with Testosterone] results in decreased expression of CFTR mRNA CTD PMID:26496021 Cftr Rat tetrachloromethane multiple interactions ISO Cftr (Mus musculus) 6480464 [Carbon Tetrachloride co-treated with Ethanol] results in increased expression of CFTR mRNA CTD PMID:30517762 Cftr Rat tetramethylpyrazine multiple interactions ISO CFTR (Homo sapiens) 6480464 1 more ... CTD PMID:15763242 Cftr Rat tetramethylpyrazine increases activity EXP 6480464 tetramethylpyrazine results in increased activity of CFTR protein CTD PMID:16015685 Cftr Rat tetramethylpyrazine increases activity ISO Cftr (Mus musculus) 6480464 tetramethylpyrazine results in increased activity of CFTR protein CTD PMID:16015685 Cftr Rat tetramethylpyrazine increases activity ISO CFTR (Homo sapiens) 6480464 tetramethylpyrazine results in increased activity of CFTR protein CTD PMID:15763242 Cftr Rat thapsigargin multiple interactions ISO CFTR (Homo sapiens) 6480464 Thapsigargin promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]] more ... CTD PMID:18230692 Cftr Rat thiocyanate affects transport ISO CFTR (Homo sapiens) 6480464 CFTR protein affects the transport of thiocyanate CTD PMID:15345749 Cftr Rat thiourea decreases expression EXP 6480464 Thiourea results in decreased expression of CFTR mRNA CTD PMID:15248066 Cftr Rat titanium dioxide increases expression ISO Cftr (Mus musculus) 6480464 titanium dioxide results in increased expression of CFTR mRNA CTD PMID:23557971 Cftr Rat titanium dioxide multiple interactions ISO Cftr (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CFTR mRNA CTD PMID:29950665 Cftr Rat titanium dioxide increases expression EXP 6480464 titanium dioxide results in increased expression of CFTR mRNA CTD PMID:30012374 Cftr Rat tremolite asbestos increases expression ISO Cftr (Mus musculus) 6480464 tremolite results in increased expression of CFTR mRNA CTD PMID:29279043 Cftr Rat tributylstannane increases expression ISO Cftr (Mus musculus) 6480464 tributyltin results in increased expression of CFTR mRNA CTD PMID:31939706 Cftr Rat trichostatin A increases expression ISO CFTR (Homo sapiens) 6480464 trichostatin A results in increased expression of CFTR mRNA CTD PMID:24935251 Cftr Rat triphenyl phosphate affects expression ISO Cftr (Mus musculus) 6480464 triphenyl phosphate affects the expression of CFTR mRNA CTD PMID:36563926 Cftr Rat triptonide increases expression ISO Cftr (Mus musculus) 6480464 triptonide results in increased expression of CFTR mRNA CTD PMID:33045310 Cftr Rat valproic acid affects expression ISO Cftr (Mus musculus) 6480464 Valproic Acid affects the expression of CFTR mRNA CTD PMID:17292431 Cftr Rat valproic acid multiple interactions ISO CFTR (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CFTR mRNA CTD PMID:27188386 Cftr Rat valproic acid increases expression ISO CFTR (Homo sapiens) 6480464 Valproic Acid results in increased expression of CFTR mRNA CTD PMID:23179753 more ... Cftr Rat vasopressin increases activity ISO Cftr (Mus musculus) 6480464 Vasopressins results in increased activity of CFTR protein CTD PMID:15513933 Cftr Rat vasotocin increases activity ISO CFTR (Homo sapiens) 6480464 Vasotocin results in increased activity of CFTR protein CTD PMID:15685210 Cftr Rat water multiple interactions EXP 6480464 1-Methyl-3-isobutylxanthine promotes the reaction [CFTR protein affects the transport of Water] more ... CTD PMID:12606488 Cftr Rat wortmannin multiple interactions ISO CFTR (Homo sapiens) 6480464 wortmannin inhibits the reaction [CGP 12177 results in increased activity of CFTR protein] CTD PMID:15563584 Cftr Rat xanthohumol multiple interactions ISO CFTR (Homo sapiens) 6480464 xanthohumol inhibits the reaction [CFTR protein results in increased export of Hyaluronic Acid] CTD PMID:23978416 Cftr Rat zinc atom increases expression ISO CFTR (Homo sapiens) 6480464 Zinc results in increased expression of CFTR mRNA CTD PMID:16870260 Cftr Rat zinc atom multiple interactions EXP 6480464 Zinc inhibits the reaction [Zinc deficiency results in increased expression of CFTR mRNA] CTD PMID:19111725 Cftr Rat zinc atom increases expression EXP 6480464 Zinc deficiency results in increased expression of CFTR mRNA CTD PMID:19111725 Cftr Rat zinc dichloride increases expression ISO CFTR (Homo sapiens) 6480464 zinc chloride results in increased expression of CFTR mRNA CTD PMID:16870260 Cftr Rat zinc(0) increases expression ISO CFTR (Homo sapiens) 6480464 Zinc results in increased expression of CFTR mRNA CTD PMID:16870260 Cftr Rat zinc(0) increases expression EXP 6480464 Zinc deficiency results in increased expression of CFTR mRNA CTD PMID:19111725 Cftr Rat zinc(0) multiple interactions EXP 6480464 Zinc inhibits the reaction [Zinc deficiency results in increased expression of CFTR mRNA] CTD PMID:19111725
