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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2332
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cftr
Name: CF transmembrane conductance regulator
Acc ID: CHEBI:16188
Term: octan-1-ol
Definition: An octanol carrying the hydroxy group at position 1.
Chemical ID: MESH:D020003
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cftrincreases activityISORGD:6195666480464CTD1-Octanol results in increased activity of CFTR protein 1-Octanol results in increased activity of CFTR protein mutant form

PMID:14967738
Cftrmultiple interactionsISORGD:6195666480464CTDGlyburide inhibits the reaction [1-Octanol results in increased activity of CFTR protein] N-2-4-bromocinnamylaminoethyl-5-isoquinolinesulfonamide inhibits the reaction [1-Octanol results in increased activity of CFTR protein]

PMID:14967738
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