CFTR (CF transmembrane conductance regulator) - Rat Genome Database

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Gene: CFTR (CF transmembrane conductance regulator) Canis lupus familiaris
Analyze
Symbol: CFTR
Name: CF transmembrane conductance regulator
RGD ID: 12125759
Description: ENCODES a protein that exhibits ATP hydrolysis activity (ortholog); bicarbonate transmembrane transporter activity (ortholog); chloride channel activity (ortholog); INVOLVED IN aging (ortholog); bicarbonate transport (ortholog); cellular response to anoxia (ortholog); ASSOCIATED WITH alcoholic pancreatitis (ortholog); allergic bronchopulmonary aspergillosis (ortholog); Alzheimer's disease (ortholog); FOUND IN apical plasma membrane (ortholog); basolateral plasma membrane (ortholog); cytoplasm (ortholog); INTERACTS WITH 3-isobutyl-1-methyl-7H-xanthine; 5-Nitro-2-(3-phenylpropylamino)benzoic acid; 8-(4-chlorophenylthio)-cAMP
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ATP-binding cassette sub-family C member 7; ATP-binding cassette transporter sub-family C member 7; cAMP-dependent chloride channel; channel conductance-controlling ATPase; cystic fibrosis transmembrane conductance regulator
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11456,290,417 - 56,452,919 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1456,290,275 - 56,453,977 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1455,685,755 - 55,848,173 (+)NCBI
ROS_Cfam_1.01456,330,071 - 56,492,372 (+)NCBI
ROS_Cfam_1.0 Ensembl1456,329,929 - 56,492,482 (+)Ensembl
UMICH_Zoey_3.11456,368,632 - 56,531,008 (+)NCBI
UNSW_CanFamBas_1.01456,049,412 - 56,212,168 (+)NCBI
UU_Cfam_GSD_1.01456,421,094 - 56,583,513 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
alcoholic pancreatitis  (ISO)
allergic bronchopulmonary aspergillosis  (ISO)
Alzheimer's disease  (ISO)
aspergillosis  (ISO)
asthma  (ISO)
autosomal recessive congenital bilateral absence of vas deferens  (ISO)
autosomal recessive polycystic kidney disease  (ISO)
azoospermia  (ISO)
Breast Neoplasms  (ISO)
bronchiectasis  (ISO)
bronchiectasis 1  (ISO)
choledochal cyst  (ISO)
cholelithiasis  (ISO)
cholestasis  (ISO)
Chronic Bronchitis  (ISO)
chronic obstructive pulmonary disease  (ISO)
Chronic Pancreatitis  (ISO)
Colorectal Neoplasms  (ISO)
congenital bilateral absence of vas deferens  (ISO)
cryptorchidism  (ISO)
cystic fibrosis  (ISO)
dental enamel hypoplasia  (ISO)
Diaphragmatic Hernia  (ISO)
duodenal atresia  (ISO)
duodenal ulcer  (ISO)
exocrine pancreatic insufficiency  (ISO)
Experimental Diabetes Mellitus  (ISO)
gastric ulcer  (ISO)
genetic disease  (ISO)
Hereditary Pancreatitis  (ISO)
Hypertriglyceridemia  (ISO)
infertility  (ISO)
influenza  (ISO)
Liver Injury  (ISO)
lung cancer  (ISO)
lung disease  (ISO)
male infertility  (ISO)
megacolon  (ISO)
Metabolic Bone Diseases  (ISO)
myocardial infarction  (ISO)
Nontuberculous Mycobacterium Infections  (ISO)
Nuchal Bleb, Familial  (ISO)
pancreatic cancer  (ISO)
pancreatitis  (ISO)
papillary renal cell carcinoma  (ISO)
pleomorphic xanthoastrocytoma  (ISO)
primary sclerosing cholangitis  (ISO)
prostatic hypertrophy  (ISO)
Pseudomonas Infections  (ISO)
pulmonary sarcoidosis  (ISO)
renal agenesis  (ISO)
renal cell carcinoma  (ISO)
respiratory syncytial virus infectious disease  (ISO)
rhinitis  (ISO)
salpingitis  (ISO)
sinusitis  (ISO)
Staphylococcal Pneumonia  (ISO)
substance-related disorder  (ISO)
tracheal disease  (ISO)
typhoid fever  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
aging  (ISO)
amelogenesis  (IEA)
bicarbonate transport  (IBA,IEA,ISO,ISS)
cellular response to anoxia  (ISO)
cellular response to cAMP  (IEA,ISS)
cellular response to forskolin  (IEA,ISS)
cellular response to heat  (ISO)
cellular response to hormone stimulus  (ISO)
chloride transmembrane transport  (IBA,IEA,ISS)
chloride transport  (IEA,ISO)
cholesterol biosynthetic process  (IEA,ISO)
cholesterol transport  (IEA,ISO)
enamel mineralization  (ISO)
establishment of localization in cell  (IEA,ISO)
inorganic anion transport  (IEA)
intracellular pH elevation  (IEA,ISS)
ion transmembrane transport  (IEA)
ion transport  (IEA)
liver regeneration  (ISO)
lung development  (ISO)
membrane hyperpolarization  (IEA,ISS)
multicellular organismal water homeostasis  (IEA,ISS)
negative regulation of type B pancreatic cell development  (ISO)
negative regulation of vascular associated smooth muscle cell apoptotic process  (ISO)
positive regulation of cyclic nucleotide-gated ion channel activity  (IEA)
positive regulation of enamel mineralization  (IEA)
positive regulation of establishment of Sertoli cell barrier  (ISO)
positive regulation of exocytosis  (IEA)
positive regulation of insulin secretion involved in cellular response to glucose stimulus  (IEA)
positive regulation of mast cell activation  (ISO)
positive regulation of voltage-gated chloride channel activity  (IEA)
regulation of membrane depolarization  (ISO)
response to amiloride  (ISO)
response to cytokine  (ISO)
response to endoplasmic reticulum stress  (IEA,ISS)
response to estrogen  (ISO)
response to peptide hormone  (ISO)
response to xenobiotic stimulus  (ISO)
sodium ion transmembrane transport  (ISO)
sperm capacitation  (IEA,ISS)
transepithelial chloride transport  (ISO)
transepithelial water transport  (IEA,ISS)
transmembrane transport  (IBA,IEA)
vasodilation  (ISO)
vesicle docking involved in exocytosis  (IEA)
water transport  (ISO)

References
Additional References at PubMed
PMID:12917688   PMID:20571109  


Genomics

Comparative Map Data
CFTR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11456,290,417 - 56,452,919 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1456,290,275 - 56,453,977 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1455,685,755 - 55,848,173 (+)NCBI
ROS_Cfam_1.01456,330,071 - 56,492,372 (+)NCBI
ROS_Cfam_1.0 Ensembl1456,329,929 - 56,492,482 (+)Ensembl
UMICH_Zoey_3.11456,368,632 - 56,531,008 (+)NCBI
UNSW_CanFamBas_1.01456,049,412 - 56,212,168 (+)NCBI
UU_Cfam_GSD_1.01456,421,094 - 56,583,513 (+)NCBI
CFTR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387117,480,025 - 117,668,665 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl7117,287,120 - 117,715,971 (+)EnsemblGRCh38hg38GRCh38
GRCh377117,120,079 - 117,308,719 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367116,907,253 - 117,095,955 (+)NCBINCBI36hg18NCBI36
Build 347116,713,967 - 116,902,666NCBI
Celera7111,928,196 - 112,116,895 (+)NCBI
Cytogenetic Map7q31.2NCBI
HuRef7111,485,640 - 111,674,189 (+)NCBIHuRef
CHM1_17117,053,369 - 117,242,163 (+)NCBICHM1_1
T2T-CHM13v2.07118,795,361 - 118,984,026 (+)NCBI
CRA_TCAGchr7v27116,515,451 - 116,704,154 (+)NCBI
Cftr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39618,170,686 - 18,322,769 (+)NCBIGRCm39mm39
GRCm39 Ensembl618,170,686 - 18,322,767 (+)Ensembl
GRCm38618,170,687 - 18,322,770 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl618,170,687 - 18,322,768 (+)EnsemblGRCm38mm10GRCm38
MGSCv37618,120,687 - 18,272,770 (+)NCBIGRCm37mm9NCBIm37
MGSCv36618,120,687 - 18,272,767 (+)NCBImm8
Celera618,244,038 - 18,394,318 (+)NCBICelera
Cytogenetic Map6A2NCBI
cM Map68.1NCBI
Cftr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2446,561,269 - 46,728,759 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl446,560,885 - 46,728,756 (+)Ensembl
Rnor_6.0442,693,263 - 42,860,679 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl442,692,836 - 42,860,676 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0442,281,040 - 42,448,571 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4443,874,852 - 44,041,870 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1444,147,212 - 44,195,889 (+)NCBI
Celera441,826,966 - 41,988,614 (+)NCBICelera
Cytogenetic Map4q21NCBI
Cftr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543223,178,866 - 23,328,382 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543223,179,645 - 23,328,347 (+)NCBIChiLan1.0ChiLan1.0
CFTR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.17122,144,821 - 122,327,511 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7122,129,798 - 122,327,864 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v07109,449,847 - 109,633,023 (+)NCBIMhudiblu_PPA_v0panPan3
Cftr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511844,970,647 - 45,124,331 (+)NCBI
SpeTri2.0NW_0049365891,565,933 - 1,719,208 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CFTR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1828,627,728 - 28,817,950 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11828,627,717 - 28,818,209 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21830,396,465 - 30,566,680 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CFTR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12186,154,313 - 86,332,436 (+)NCBIChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604217,387,997 - 17,576,802 (-)NCBIVero_WHO_p1.0
Cftr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248271,704,733 - 1,893,579 (-)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 3 2
Low 2 3 7 3
Below cutoff 5 19 6 6 6 6 2 5 8 5 6

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000005518   ⟹   ENSCAFP00000005112
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1456,290,275 - 56,453,977 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000059721   ⟹   ENSCAFP00000063328
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1456,317,631 - 56,453,977 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000062415   ⟹   ENSCAFP00000049995
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1456,290,275 - 56,453,977 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000062635   ⟹   ENSCAFP00000061141
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1456,290,275 - 56,453,977 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000063866   ⟹   ENSCAFP00000045808
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1456,290,275 - 56,453,977 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000074449   ⟹   ENSCAFP00000060014
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1456,290,275 - 56,417,134 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845016496   ⟹   ENSCAFP00845012830
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1456,329,929 - 56,492,482 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845016695   ⟹   ENSCAFP00845012992
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1456,329,929 - 56,492,482 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845016862   ⟹   ENSCAFP00845013119
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1456,329,929 - 56,492,482 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845017001   ⟹   ENSCAFP00845013242
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1456,329,929 - 56,492,372 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845017081   ⟹   ENSCAFP00845013302
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1456,329,929 - 56,456,822 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845017129   ⟹   ENSCAFP00845013342
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1456,357,101 - 56,492,482 (+)Ensembl
RefSeq Acc Id: NM_001007143   ⟹   NP_001007144
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11456,290,417 - 56,452,919 (+)NCBI
Dog10K_Boxer_Tasha1455,685,755 - 55,848,173 (+)NCBI
ROS_Cfam_1.01456,330,071 - 56,492,372 (+)NCBI
UMICH_Zoey_3.11456,368,632 - 56,531,008 (+)NCBI
UNSW_CanFamBas_1.01456,049,412 - 56,212,168 (+)NCBI
UU_Cfam_GSD_1.01456,421,094 - 56,583,513 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001007144 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAR16271 (Get FASTA)   NCBI Sequence Viewer  
  AAV40962 (Get FASTA)   NCBI Sequence Viewer  
  Q5U820 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001007144   ⟸   NM_001007143
- UniProtKB: Q5U820 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSCAFP00000005112   ⟸   ENSCAFT00000005518
RefSeq Acc Id: ENSCAFP00000060014   ⟸   ENSCAFT00000074449
RefSeq Acc Id: ENSCAFP00000063328   ⟸   ENSCAFT00000059721
RefSeq Acc Id: ENSCAFP00000045808   ⟸   ENSCAFT00000063866
RefSeq Acc Id: ENSCAFP00000061141   ⟸   ENSCAFT00000062635
RefSeq Acc Id: ENSCAFP00000049995   ⟸   ENSCAFT00000062415
RefSeq Acc Id: ENSCAFP00845013242   ⟸   ENSCAFT00845017001
RefSeq Acc Id: ENSCAFP00845013119   ⟸   ENSCAFT00845016862
RefSeq Acc Id: ENSCAFP00845013342   ⟸   ENSCAFT00845017129
RefSeq Acc Id: ENSCAFP00845013302   ⟸   ENSCAFT00845017081
RefSeq Acc Id: ENSCAFP00845012830   ⟸   ENSCAFT00845016496
RefSeq Acc Id: ENSCAFP00845012992   ⟸   ENSCAFT00845016695
Promoters
RGD ID:13685828
Promoter ID:EPDNEW_C3897
Type:multiple initiation site
Name:CFTR_1
Description:cystic fibrosis transmembrane conductance regulator
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11456,290,342 - 56,290,402EPDNEW
Damaging Variants


Assembly: CanFam3.1

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
14 56405123 56405124 C T snv Tibetan Mastiff (TM4)
14 56452833 56452834 C T snv Australian Cattle dog (AC065), Chinese Crested (SRS713815), Lagotto Romagnolo (LR538), Jack Russell Terrier (JR0034), Lagotto Romagnolo (LR1030), Lagotto Romagnolo (LR494), Australian Cattle dog (AC023), Golden Retriever (GR0855)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000003429 Ensembl
  ENSCAFG00030012224 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSCAFG00040004710 UniProtKB/TrEMBL
  ENSCAFG00845009171 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00030021148 UniProtKB/Swiss-Prot
  ENSCAFP00030021346.1 UniProtKB/TrEMBL
  ENSCAFP00030021475.1 UniProtKB/TrEMBL
  ENSCAFP00030021544.1 UniProtKB/TrEMBL
  ENSCAFP00040008712 UniProtKB/TrEMBL
  ENSCAFP00040008799 UniProtKB/TrEMBL
  ENSCAFP00040008847 UniProtKB/TrEMBL
  ENSCAFP00040008893 UniProtKB/TrEMBL
  ENSCAFP00845012830 ENTREZGENE
  ENSCAFP00845012830.1 UniProtKB/TrEMBL
  ENSCAFP00845012992.1 UniProtKB/TrEMBL
  ENSCAFP00845013119.1 UniProtKB/TrEMBL
  ENSCAFP00845013242.1 UniProtKB/TrEMBL
  ENSCAFP00845013302.1 UniProtKB/TrEMBL
  ENSCAFP00845013342.1 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00030024246 UniProtKB/Swiss-Prot
  ENSCAFT00030024457.1 UniProtKB/TrEMBL
  ENSCAFT00030024588.1 UniProtKB/TrEMBL
  ENSCAFT00030024676.1 UniProtKB/TrEMBL
  ENSCAFT00040010051 UniProtKB/TrEMBL
  ENSCAFT00040010144 UniProtKB/TrEMBL
  ENSCAFT00040010197 UniProtKB/TrEMBL
  ENSCAFT00040010247 UniProtKB/TrEMBL
  ENSCAFT00845016496 ENTREZGENE
  ENSCAFT00845016496.1 UniProtKB/TrEMBL
  ENSCAFT00845016695.1 UniProtKB/TrEMBL
  ENSCAFT00845016862.1 UniProtKB/TrEMBL
  ENSCAFT00845017001.1 UniProtKB/TrEMBL
  ENSCAFT00845017081.1 UniProtKB/TrEMBL
  ENSCAFT00845017129.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1560.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC1_TM_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC1_TM_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC_transporter-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC_transporter_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CFTR/ABCC7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CFTR_reg_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report cfa:492302 UniProtKB/Swiss-Prot
NCBI Gene CFTR ENTREZGENE
PANTHER PTHR24223:SF19 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam ABC_membrane UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC_tran UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CFTR_R UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS CYSFIBREGLTR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ABC_TM1F UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC_TRANSPORTER_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC_TRANSPORTER_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART AAA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF90123 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGRFAMs CFTR_protein UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8C0N7L4_CANLF UniProtKB/TrEMBL
  A0A8C0N9K8_CANLF UniProtKB/TrEMBL
  A0A8C0NEW4_CANLF UniProtKB/TrEMBL
  A0A8C0Q568_CANLF UniProtKB/TrEMBL
  A0A8C0Q5A4_CANLF UniProtKB/TrEMBL
  A0A8C0QCS8_CANLF UniProtKB/TrEMBL
  A0A8C0QD69_CANLF UniProtKB/TrEMBL
  A0A8I3N8K9_CANLF UniProtKB/TrEMBL
  A0A8I3N934_CANLF UniProtKB/TrEMBL
  A0A8I3NC62_CANLF UniProtKB/TrEMBL
  A0A8I3NDN0_CANLF UniProtKB/TrEMBL
  A0A8I3NDV7_CANLF UniProtKB/TrEMBL
  A0A8I3RV68_CANLF UniProtKB/TrEMBL
  CFTR_CANLF UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary A0M8V3 UniProtKB/Swiss-Prot
VGNC ID VGNC:39180 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-05-21 CFTR  CF transmembrane conductance regulator  CFTR  cystic fibrosis transmembrane conductance regulator  Symbol and/or name change 5135510 APPROVED