GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cftr | multiple interactions | EXP | | 6480464 | CTD | 1-Methyl-3-isobutylxanthine promotes the reaction [CFTR protein affects the transport of Water] | PMID:12606488 | Cftr | increases activity | ISO | CFTR (Homo sapiens) | 6480464 | CTD | 1-Methyl-3-isobutylxanthine results in increased activity of CFTR protein | PMID:12914781 | Cftr | multiple interactions | ISO | Cftr (Mus musculus) | 6480464 | CTD | [1-Methyl-3-isobutylxanthine co-treated with Colforsin] results in increased activity of CFTR protein | PMID:15517342 | Cftr | multiple interactions | ISO | CFTR (Homo sapiens) | 6480464 | CTD | 1-Methyl-3-isobutylxanthine promotes the reaction [CFTR protein affects the export of Chlorides]; [1-Methyl-3-isobutylxanthine co-treated with 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP] results in increased activity of CFTR protein mutant form; [1-Methyl-3-isobutylxanthine co-treated with Colforsin] results in increased activity of CFTR protein; [1-Methyl-3-isobutylxanthine co-treated with Colforsin] results in increased activity of CFTR protein mutant form; [Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of CFTR protein | PMID:12914781 PMID:15163550 PMID:15763242 PMID:16027156 | | ||||||||||||||||||||||
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