GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cftr | affects export | ISO | Cftr (Mus musculus) | 6480464 | CTD | CFTR protein affects the export of Glutathione | PMID:15561710 | Cftr | decreases activity | ISO | CFTR (Homo sapiens) | 6480464 | CTD | Glutathione analog results in decreased activity of CFTR protein | PMID:15657297 | Cftr | multiple interactions | ISO | CFTR (Homo sapiens) | 6480464 | CTD | [Bicarbonates co-treated with Glutathione co-treated with Ascorbic Acid] results in increased activity of CFTR protein; [Glutathione co-treated with Diamide] results in decreased activity of CFTR protein; Dithiothreitol inhibits the reaction [Glutathione results in decreased activity of CFTR protein]; Ethylmaleimide inhibits the reaction [Glutathione results in decreased activity of CFTR protein] | PMID:15657297 PMID:15857825 PMID:32374624 | | ||||||||||||||||||||||
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