Gene: Adra1a (adrenoceptor alpha 1A) Rattus norvegicus
Symbol: Adra1a
Name: adrenoceptor alpha 1A
Description: ENCODES a protein that exhibits alpha1-adrenergic receptor activity; protein heterodimerization activity (ortholog); INVOLVED IN activation of phospholipase C activity; aging; calcium ion transport into cytosol; PARTICIPATES IN alfentanil pharmacodynamics pathway; bupivacaine pharmacodynamics pathway; buprenorphine pharmacodynamics pathway; ASSOCIATED WITH bladder neck obstruction; Brain Injuries; Diabetes Mellitus, Experimental ; FOUND IN dopaminergic synapse; GABA-ergic synapse; glutamatergic synapse; INTERACTS WITH (6aR,9R)-N-[(2S)-1-hydroxybutan-2-yl]-4,7-dimethyl-6,6a,8,9-tetrahydroindolo[4,3-fg]quinoline-9-carboxamide; (R)-adrenaline; (R)-noradrenaline
Type: protein-coding
Also known as: Adra1c; adrenergic alpha 1c receptor; adrenergic receptor alpha 1c; adrenergic receptor alpha 1c subtype; adrenergic receptor, alpha 1a; adrenergic receptor, alpha 1c; adrenergic, alpha-1A-, receptor; alpha 1A-adrenoceptor; alpha 1A-adrenoreceptor; alpha 1C-adrenergic receptor; alpha-1A adrenergic receptor; alpha-1A adrenoceptor; alpha-1A adrenoreceptor; alpha-1C adrenergic receptor
Homo sapiens (human) : ADRA1A (adrenoceptor alpha 1A)  HGNC  Alliance
Mus musculus (house mouse) : Adra1a (adrenergic receptor, alpha 1a)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Adra1a (adrenoceptor alpha 1A)
Pan paniscus (bonobo/pygmy chimpanzee) : ADRA1A (adrenoceptor alpha 1A)
Canis lupus familiaris (dog) : ADRA1A (adrenoceptor alpha 1A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adra1a (adrenoceptor alpha 1A)
Sus scrofa (pig) : ADRA1A (adrenoceptor alpha 1A)
more info ...
Allele / Splice: Adra1am1Mcwi  
Genetic Models: FHH-Adra1am1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01543,296,997 - 43,398,314 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01548,197,628 - 48,297,316 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41546,173,429 - 46,263,198 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11546,189,187 - 46,279,387 (+)NCBI
Celera1540,502,534 - 40,590,531 (+)NCBICelera
Cytogenetic Map15p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Adra1a
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2055
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE