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Gene: ADRA1A (adrenoceptor alpha 1A) Homo sapiens
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Symbol: ADRA1A
Name: adrenoceptor alpha 1A
Description: Exhibits protein heterodimerization activity. Involved in positive regulation of MAPK cascade. Localizes to the cytoplasm; nuclear membrane; and plasma membrane. Implicated in Alzheimer's disease and hypertension.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ADRA1C; ADRA1L1; adrenergic receptor, alpha 1a; adrenergic, alpha -1A-, receptor; adrenergic, alpha-1A-, receptor; adrenergic, alpha-1A-, receptor variant 1; adrenergic, alpha-1A-, receptor variant 11; adrenergic, alpha-1A-, receptor variant 2; adrenergic, alpha-1A-, receptor variant 3; adrenergic, alpha-1A-, receptor variant 4; adrenergic, alpha-1A-, receptor variant 5; adrenergic, alpha-1A-, receptor variant 6; adrenergic, alpha-1A-, receptor variant 8; adrenergic, alpha-1A-, receptor variant 9; adrenergic, alpha-1C-, receptor; alpha-1A adrenergic receptor; alpha-1A adrenoceptor; alpha-1A adrenoreceptor; alpha-1C adrenergic receptor; alpha-adrenergic receptor 1c; ALPHA1AAR; G protein coupled receptor
Orthologs:
Mus musculus (house mouse) : Adra1a (adrenergic receptor, alpha 1a)  MGI  Alliance
Rattus norvegicus (Norway rat) : Adra1a (adrenoceptor alpha 1A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Adra1a (adrenoceptor alpha 1A)
Pan paniscus (bonobo/pygmy chimpanzee) : ADRA1A (adrenoceptor alpha 1A)
Canis lupus familiaris (dog) : ADRA1A (adrenoceptor alpha 1A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adra1a (adrenoceptor alpha 1A)
Sus scrofa (pig) : ADRA1A (adrenoceptor alpha 1A)
Chlorocebus sabaeus (African green monkey) : ADRA1A (adrenoceptor alpha 1A)
Heterocephalus glaber (naked mole-rat) : Adra1a (adrenoceptor alpha 1A)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl826,748,150 - 26,867,278 (-)Ensembl
GRCh38826,738,113 - 26,870,994 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37826,605,667 - 26,727,003 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36826,661,584 - 26,778,839 (-)NCBINCBI36hg18NCBI36
Build 34826,679,287 - 26,778,603NCBI
Celera825,568,607 - 25,685,865 (-)NCBI
Cytogenetic Map8p21.2NCBI
HuRef825,150,527 - 25,267,740 (-)NCBIHuRef
CHM1_1826,807,550 - 26,926,634 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on ADRA1A
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736081
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.