(+)-alpha-tocopherol multiple interactions ISO RGD:1319531 6480464 [alpha-Tocopherol co-treated with Paraquat] results in increased expression of SLC7A11 mRNA; more ... CTD PMID:24530478 (-)-demecolcine increases expression ISO RGD:1319531 6480464 Demecolcine results in increased expression of SLC7A11 mRNA CTD PMID:23649840 (S)-AMPA multiple interactions EXP 6480464 alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid inhibits the reaction [Propofol results in decreased expression of SLC7A11 protein] CTD PMID:28663055 1,3-benzothiazole-2-thiol increases expression ISO RGD:1319531 6480464 captax results in increased expression of SLC7A11 mRNA CTD PMID:24211530 17alpha-ethynylestradiol affects expression ISO RGD:1319531 6480464 Ethinyl Estradiol affects the expression of SLC7A11 mRNA CTD PMID:20170705 17beta-estradiol affects expression ISO RGD:1319531 6480464 Estradiol affects the expression of SLC7A11 mRNA CTD PMID:22574217 17beta-estradiol increases expression ISO RGD:1319531 6480464 Estradiol results in increased expression of SLC7A11 mRNA CTD PMID:15159206 more ... 17beta-estradiol multiple interactions EXP 6480464 [bisphenol A co-treated with Estradiol] results in increased expression of SLC7A11 mRNA CTD PMID:26496021 17beta-estradiol decreases expression ISO RGD:1319531 6480464 Estradiol results in decreased expression of SLC7A11 mRNA CTD PMID:16474171 PMID:19167446 2,2',4,4'-Tetrabromodiphenyl ether increases expression ISO RGD:1319531 6480464 2,2',4,4'-tetrabromodiphenyl ether analog results in increased expression of SLC7A11 mRNA; more ... CTD PMID:19095052 PMID:25305463 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of SLC7A11 mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1319531 6480464 [Endosulfan co-treated with Tetrachlorodibenzodioxin] results in increased expression of SLC7A11 mRNA CTD PMID:26159488 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1319531 6480464 Tetrachlorodibenzodioxin results in increased expression of SLC7A11 mRNA CTD PMID:26159488 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1319532 6480464 Tetrachlorodibenzodioxin affects the expression of SLC7A11 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:1319531 6480464 Tetrachlorodibenzodioxin results in decreased expression of SLC7A11 mRNA CTD PMID:21632981 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1319531 6480464 Tetrachlorodibenzodioxin affects the expression of SLC7A11 mRNA CTD PMID:20106945 PMID:22298810 2-(chloromethyl)pyridine increases expression ISO RGD:1319531 6480464 2-chloromethylpyridine results in increased expression of SLC7A11 mRNA CTD PMID:26198647 2-butoxyethanol increases expression ISO RGD:1319532 6480464 n-butoxyethanol results in increased expression of SLC7A11 mRNA CTD PMID:19812364 2-HYDROXY-(5-([4-(2-PYRIDINYLAMINO)SULFONYL]PHENYL)AZO)BENZOIC ACID multiple interactions ISO RGD:1319532 6480464 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[Sulfasalazine results in decreased activity of SLC7A11 protein] which results in increased expression of CAV1 mRNA]; more ... CTD PMID:19015640 PMID:19576933 2-HYDROXY-(5-([4-(2-PYRIDINYLAMINO)SULFONYL]PHENYL)AZO)BENZOIC ACID decreases activity ISO RGD:1319531 6480464 Sulfasalazine results in decreased activity of SLC7A11 protein CTD PMID:20007406 2-HYDROXY-(5-([4-(2-PYRIDINYLAMINO)SULFONYL]PHENYL)AZO)BENZOIC ACID decreases activity ISO RGD:1319532 6480464 Sulfasalazine results in decreased activity of SLC7A11 protein CTD PMID:19015640 2-tert-butylhydroquinone increases expression ISO RGD:1319532 6480464 2-tert-butylhydroquinone results in increased expression of SLC7A11 mRNA CTD PMID:19183254 3,3',4,4',5-pentachlorobiphenyl increases expression ISO RGD:1319531 6480464 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLC7A11 mRNA CTD PMID:19692669 PMID:23146750 3,3',4,4'-tetrachlorobiphenyl affects expression ISO RGD:1319531 6480464 3,4,3',4'-tetrachlorobiphenyl affects the expression of SLC7A11 mRNA CTD PMID:20638727 3,3',5,5'-tetrabromobisphenol A increases expression ISO RGD:1319532 6480464 tetrabromobisphenol A results in increased expression of SLC7A11 mRNA CTD PMID:25172293 3,3',5,5'-tetrabromobisphenol A increases expression ISO RGD:1319531 6480464 tetrabromobisphenol A results in increased expression of SLC7A11 mRNA CTD PMID:25424538 3-chloropropane-1,2-diol increases expression EXP 6480464 alpha-Chlorohydrin results in increased expression of SLC7A11 mRNA CTD PMID:28522335 3-methyl-3H-imidazo[4,5-f]quinolin-2-amine increases expression ISO RGD:1319531 6480464 2-amino-3-methylimidazo(4,5-f)quinoline results in increased expression of SLC7A11 mRNA CTD PMID:26198647 4,4'-methylene-bis-(2-chloroaniline) increases expression ISO RGD:1319531 6480464 Methylenebis(chloroaniline) results in increased expression of SLC7A11 mRNA CTD PMID:26198647 4-hydroxynon-2-enal multiple interactions ISO RGD:1319532 6480464 [APC protein mutant form results in increased expression of SLC7A11 mRNA] which affects the metabolism of 4-hydroxy-2-nonenal CTD PMID:21967605 4-nitro-1,2-phenylenediamine increases expression ISO RGD:1319531 6480464 1,2-diamino-4-nitrobenzene results in increased expression of SLC7A11 mRNA CTD PMID:26198647 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of SLC7A11 mRNA CTD PMID:24780913 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of SLC7A11 mRNA CTD PMID:25825206 6alpha-methylprednisolone decreases expression ISO RGD:1319531 6480464 Methylprednisolone results in decreased expression of SLC7A11 mRNA CTD PMID:19192274 7beta-aminocephalosporanic acid increases expression ISO RGD:1319531 6480464 7-aminocephalosporanic acid results in increased expression of SLC7A11 mRNA CTD PMID:24211530 8-bromo-3',5'-cyclic AMP decreases expression ISO RGD:1319531 6480464 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of SLC7A11 mRNA CTD PMID:22079614 acrolein increases expression ISO RGD:1319531 6480464 Acrolein results in increased expression of SLC7A11 mRNA CTD PMID:24211530 acrylamide increases expression ISO RGD:1319531 6480464 Acrylamide results in increased expression of SLC7A11 mRNA CTD PMID:23287710 acrylamide increases expression EXP 6480464 Acrylamide results in increased expression of SLC7A11 mRNA CTD PMID:28959563 aflatoxin B1 affects expression ISO RGD:1319531 6480464 Aflatoxin B1 affects the expression of SLC7A11 protein CTD PMID:20106945 aflatoxin B1 increases expression ISO RGD:1319531 6480464 Aflatoxin B1 results in increased expression of SLC7A11 mRNA CTD PMID:22100608 PMID:27153756 aflatoxin B1 decreases methylation ISO RGD:1319531 6480464 Aflatoxin B1 results in decreased methylation of SLC7A11 gene CTD PMID:27153756 aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of SLC7A11 mRNA CTD PMID:23630614 PMID:25378103 aflatoxin B1 decreases expression ISO RGD:1319531 6480464 Aflatoxin B1 results in decreased expression of SLC7A11 mRNA CTD PMID:21632981 aflatoxin B1 decreases expression ISO RGD:1319532 6480464 Aflatoxin B1 results in decreased expression of SLC7A11 mRNA CTD PMID:19770486 all-trans-retinoic acid decreases expression ISO RGD:1319531 6480464 Tretinoin results in decreased expression of SLC7A11 mRNA CTD PMID:21934132 PMID:23724009 ammonium hexachloroplatinate increases expression ISO RGD:1319531 6480464 ammonium hexachloroplatinate results in increased expression of SLC7A11 mRNA CTD PMID:24211530 ampicillin decreases expression ISO RGD:1319531 6480464 Ampicillin results in decreased expression of SLC7A11 mRNA CTD PMID:21632981 PMID:26198647 andrographolide increases expression ISO RGD:1319532 6480464 andrographolide results in increased expression of SLC7A11 mRNA CTD PMID:19737545 arachidonic acid increases expression ISO RGD:1319531 6480464 Arachidonic Acid results in increased expression of SLC7A11 mRNA CTD PMID:16704987 arsane affects methylation ISO RGD:1319531 6480464 Arsenic affects the methylation of SLC7A11 gene CTD PMID:25304211 arsenic atom affects methylation ISO RGD:1319531 6480464 Arsenic affects the methylation of SLC7A11 gene CTD PMID:25304211 arsenic(3+) affects methylation ISO RGD:1319531 6480464 Arsenic affects the methylation of SLC7A11 gene CTD PMID:25304211 azathioprine decreases expression ISO RGD:1319531 6480464 Azathioprine results in decreased expression of SLC7A11 mRNA CTD PMID:19192274 azathioprine increases expression ISO RGD:1319531 6480464 Azathioprine results in increased expression of SLC7A11 mRNA CTD PMID:22623647 PMID:26198647 belinostat decreases expression ISO RGD:1319531 6480464 belinostat results in decreased expression of SLC7A11 mRNA CTD PMID:27188386 benzene increases expression ISO RGD:1319531 6480464 Benzene results in increased expression of SLC7A11 mRNA CTD PMID:20359517 PMID:21843810 benzidine increases expression ISO RGD:1319531 6480464 benzidine results in increased expression of SLC7A11 mRNA CTD PMID:26198647 benzo[a]pyrene affects expression ISO RGD:1319531 6480464 Benzo(a)pyrene affects the expression of SLC7A11 mRNA CTD PMID:20106945 more ... benzo[a]pyrene increases expression ISO RGD:1319531 6480464 Benzo(a)pyrene results in increased expression of SLC7A11 mRNA CTD PMID:20064835 more ... benzo[a]pyrene decreases expression ISO RGD:1319531 6480464 Benzo(a)pyrene metabolite results in decreased expression of SLC7A11 mRNA CTD PMID:24356939 benzo[a]pyrene increases expression ISO RGD:1319532 6480464 Benzo(a)pyrene results in increased expression of SLC7A11 mRNA CTD PMID:19770486 more ... benzo[a]pyrene diol epoxide I decreases expression ISO RGD:1319531 6480464 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of SLC7A11 mRNA CTD PMID:19150397 PMID:20018196 bicalutamide increases expression ISO RGD:1319531 6480464 bicalutamide results in increased expression of SLC7A11 mRNA CTD PMID:15638997 bilirubin IXalpha multiple interactions ISO RGD:1319531 6480464 [[[Bilirubin results in increased activity of [SLC7A11 protein co-treated with SLC3A2 protein]] which results in increased uptake of Cystine] which results in increased abundance of Glutathione] which results in decreased susceptibility to Hydrogen Peroxide; more ... CTD PMID:22216172 bilirubin IXalpha increases expression ISO RGD:1319531 6480464 Bilirubin results in increased expression of SLC7A11 mRNA CTD PMID:22216172 bisphenol A affects expression ISO RGD:1319531 6480464 bisphenol A affects the expression of SLC7A11 mRNA CTD PMID:20170705 bisphenol A increases expression ISO RGD:1319531 6480464 bisphenol A results in increased expression of SLC7A11 mRNA CTD PMID:29275510 bisphenol A decreases expression ISO RGD:1319531 6480464 bisphenol A results in decreased expression of SLC7A11 mRNA CTD PMID:16474171 more ... bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of SLC7A11 mRNA CTD PMID:25181051 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of SLC7A11 mRNA CTD PMID:26982218 bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with Estradiol] results in increased expression of SLC7A11 mRNA CTD PMID:26496021 buta-1,3-diene increases expression ISO RGD:1319532 6480464 1,3-butadiene results in increased expression of SLC7A11 mRNA CTD PMID:29038090 butanal decreases expression ISO RGD:1319531 6480464 butyraldehyde results in decreased expression of SLC7A11 mRNA CTD PMID:26079696 cadmium atom decreases expression ISO RGD:1319531 6480464 Cadmium results in decreased expression of SLC7A11 mRNA CTD PMID:24376830 cadmium atom multiple interactions ISO RGD:1319531 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SLC7A11 mRNA CTD PMID:29741670 cadmium atom increases expression ISO RGD:1319531 6480464 Cadmium results in increased expression of SLC7A11 mRNA CTD PMID:21172416 PMID:23369406 cadmium dichloride increases expression ISO RGD:1319531 6480464 Cadmium Chloride results in increased expression of SLC7A11 mRNA CTD PMID:25596134 cadmium dichloride multiple interactions ISO RGD:1319531 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SLC7A11 mRNA CTD PMID:29741670 cannabidiol increases expression ISO RGD:1319532 6480464 Cannabidiol results in increased expression of SLC7A11 mRNA CTD PMID:21542829 carbamazepine affects expression ISO RGD:1319531 6480464 Carbamazepine affects the expression of SLC7A11 mRNA CTD PMID:25979313 carbon nanotube increases expression ISO RGD:1319532 6480464 Nanotubes, Carbon results in increased expression of SLC7A11 mRNA CTD PMID:25554681 ceftriaxone multiple interactions EXP 6480464 Ceftriaxone inhibits the reaction [Cocaine results in decreased expression of SLC7A11 protein] CTD PMID:19717140 celastrol decreases response to substance ISO RGD:1319531 6480464 SLC7A11 protein results in decreased susceptibility to tripterine CTD PMID:20007406 celastrol increases expression ISO RGD:1319531 6480464 tripterine results in increased expression of SLC7A11 mRNA CTD PMID:17010675 chloroacetaldehyde increases expression ISO RGD:1319531 6480464 chloroacetaldehyde results in increased expression of SLC7A11 mRNA CTD PMID:25596134 chloropicrin increases expression ISO RGD:1319531 6480464 chloropicrin results in increased expression of SLC7A11 mRNA CTD PMID:24211530 chloroprene increases expression ISO RGD:1319532 6480464 Chloroprene results in increased expression of SLC7A11 mRNA CTD PMID:23125180 chlorpyrifos decreases expression EXP 6480464 Chlorpyrifos results in decreased expression of SLC7A11 mRNA CTD PMID:20600679 chlorpyrifos increases expression ISO RGD:1319531 6480464 Chlorpyrifos results in increased expression of SLC7A11 mRNA CTD PMID:25424538 chlorpyrifos multiple interactions ISO RGD:1319532 6480464 [Chlorpyrifos co-treated with NGF protein] results in decreased expression of SLC7A11 mRNA CTD PMID:20600679 choline multiple interactions ISO RGD:1319532 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SLC7A11 mRNA CTD PMID:20938992 cisplatin affects response to substance ISO RGD:1319531 6480464 SLC7A11 protein affects the susceptibility to Cisplatin CTD PMID:16217747 cisplatin decreases expression ISO RGD:1319531 6480464 Cisplatin results in decreased expression of SLC7A11 mRNA CTD PMID:26198647 cisplatin increases expression ISO RGD:1319531 6480464 Cisplatin results in increased expression of SLC7A11 mRNA CTD PMID:27594783 cisplatin increases expression ISO RGD:1319532 6480464 Cisplatin results in increased expression of SLC7A11 mRNA CTD PMID:21151649 cobalt dichloride increases expression EXP 6480464 cobaltous chloride results in increased expression of SLC7A11 mRNA CTD PMID:24386269 cobalt dichloride increases expression ISO RGD:1319531 6480464 cobaltous chloride results in increased expression of SLC7A11 mRNA CTD PMID:22941251 PMID:24356939 cocaine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Cocaine results in decreased expression of SLC7A11 protein]; more ... CTD PMID:19717140 cocaine decreases expression EXP 6480464 Cocaine results in decreased expression of SLC7A11 protein CTD PMID:19717140 copper atom increases expression EXP 6480464 Copper deficiency results in increased expression of SLC7A11 mRNA CTD PMID:26033743 copper atom multiple interactions ISO RGD:1319531 6480464 [NSC 689534 binds to Copper] which results in increased expression of SLC7A11 mRNA CTD PMID:20971185 copper(0) increases expression EXP 6480464 Copper deficiency results in increased expression of SLC7A11 mRNA CTD PMID:26033743 copper(0) multiple interactions ISO RGD:1319531 6480464 [NSC 689534 binds to Copper] which results in increased expression of SLC7A11 mRNA CTD PMID:20971185 copper(2+) increases expression EXP 6480464 Copper deficiency results in increased expression of SLC7A11 mRNA CTD PMID:26033743 copper(2+) multiple interactions ISO RGD:1319531 6480464 [NSC 689534 binds to Copper] which results in increased expression of SLC7A11 mRNA CTD PMID:20971185 copper(II) sulfate decreases expression ISO RGD:1319531 6480464 Copper Sulfate results in decreased expression of SLC7A11 mRNA CTD PMID:20599845 copper(II) sulfate increases expression ISO RGD:1319531 6480464 Copper Sulfate results in increased expression of SLC7A11 mRNA CTD PMID:19549813 PMID:20599845 coumaphos increases expression ISO RGD:1319531 6480464 Coumaphos results in increased expression of SLC7A11 mRNA CTD PMID:26198647 coumestrol decreases expression ISO RGD:1319531 6480464 Coumestrol results in decreased expression of SLC7A11 mRNA CTD PMID:19167446 coumestrol multiple interactions ISO RGD:1319531 6480464 [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SLC7A11 mRNA CTD PMID:19167446 crocidolite asbestos affects expression ISO RGD:1319531 6480464 Asbestos, Crocidolite affects the expression of SLC7A11 mRNA CTD PMID:25757056 curcumin increases expression ISO RGD:1319531 6480464 Curcumin results in increased expression of SLC7A11 mRNA CTD PMID:17999991 curcumin increases expression ISO RGD:1319532 6480464 Curcumin results in increased expression of SLC7A11 mRNA CTD PMID:19183254 cyclophosphamide affects expression ISO RGD:1319531 6480464 Cyclophosphamide affects the expression of SLC7A11 mRNA CTD PMID:23824090 cyclophosphamide decreases expression ISO RGD:1319531 6480464 Cyclophosphamide metabolite results in decreased expression of SLC7A11 mRNA CTD PMID:24356939 cyclosporin A increases expression ISO RGD:1319532 6480464 Cyclosporine results in increased expression of SLC7A11 mRNA CTD PMID:19770486 cyclosporin A increases expression ISO RGD:1319531 6480464 Cyclosporine results in increased expression of SLC7A11 mRNA CTD PMID:19159671 more ... cyclosporin A increases expression EXP 6480464 Cyclosporine results in increased expression of SLC7A11 mRNA CTD PMID:25596134 cypermethrin increases expression ISO RGD:1319531 6480464 cypermethrin results in increased expression of SLC7A11 mRNA CTD PMID:25424538 DDT increases expression ISO RGD:1319531 6480464 DDT results in increased expression of SLC7A11 mRNA CTD PMID:26198647 diazinon increases expression ISO RGD:1319531 6480464 Diazinon results in increased expression of SLC7A11 mRNA CTD PMID:24356939 PMID:26198647 dichloromethane increases expression ISO RGD:1319531 6480464 Methylene Chloride results in increased expression of SLC7A11 mRNA CTD PMID:20359517 diclofenac decreases expression ISO RGD:1319531 6480464 Diclofenac results in decreased expression of SLC7A11 mRNA CTD PMID:19192274 dieldrin multiple interactions ISO RGD:1319532 6480464 [Dieldrin co-treated with NGF protein] results in increased expression of SLC7A11 mRNA CTD PMID:20600679 diethyl maleate multiple interactions ISO RGD:1319532 6480464 NFE2L2 gene mutant form inhibits the reaction [diethyl maleate results in increased expression of SLC7A11 mRNA] CTD PMID:12235164 diethyl maleate increases expression ISO RGD:1319532 6480464 diethyl maleate results in increased expression of SLC7A11 mRNA CTD PMID:12235164 diethylstilbestrol increases expression ISO RGD:1319531 6480464 Diethylstilbestrol results in increased expression of SLC7A11 mRNA CTD PMID:15159206 diethylstilbestrol decreases expression ISO RGD:1319531 6480464 Diethylstilbestrol results in decreased expression of SLC7A11 mRNA CTD PMID:26198647 dioxygen decreases expression ISO RGD:1319531 6480464 Oxygen deficiency results in decreased expression of SLC7A11 mRNA CTD PMID:25596134 PMID:26516004 dioxygen multiple interactions EXP 6480464 [Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased expression of SLC7A11 protein CTD PMID:29045497 diquat increases expression ISO RGD:1319531 6480464 Diquat results in increased expression of SLC7A11 mRNA CTD PMID:21172416 disodium selenite increases expression ISO RGD:1319531 6480464 Sodium Selenite results in increased expression of SLC7A11 mRNA CTD PMID:24383545 doramapimod increases expression ISO RGD:1319532 6480464 BIRB 796 results in increased expression of SLC7A11 mRNA CTD PMID:21328587 dorsomorphin multiple interactions ISO RGD:1319531 6480464 [NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLC7A11 mRNA; more ... CTD PMID:27188386 doxorubicin decreases expression ISO RGD:1319531 6480464 Doxorubicin results in decreased expression of SLC7A11 mRNA CTD PMID:29803840 elemental selenium increases import ISO RGD:1319531 6480464 SLC7A11 mRNA results in increased import of Selenium CTD PMID:28070112 elesclomol multiple interactions ISO RGD:1319531 6480464 Acetylcysteine inhibits the reaction [elesclomol results in increased expression of SLC7A11 mRNA] CTD PMID:18723479 elesclomol increases expression ISO RGD:1319531 6480464 elesclomol results in increased expression of SLC7A11 mRNA CTD PMID:18723479 endosulfan multiple interactions ISO RGD:1319531 6480464 [Endosulfan co-treated with Tetrachlorodibenzodioxin] results in increased expression of SLC7A11 mRNA CTD PMID:26159488 endosulfan increases expression EXP 6480464 Endosulfan results in increased expression of SLC7A11 mRNA CTD PMID:29391264 Enterolactone decreases expression ISO RGD:1319531 6480464 2,3-bis(3'-hydroxybenzyl)butyrolactone results in decreased expression of SLC7A11 mRNA CTD PMID:19167446 Enterolactone multiple interactions ISO RGD:1319531 6480464 [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SLC7A11 mRNA CTD PMID:19167446 entinostat multiple interactions ISO RGD:1319531 6480464 [NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLC7A11 mRNA CTD PMID:27188386 entinostat increases expression ISO RGD:1319531 6480464 entinostat results in increased expression of SLC7A11 mRNA CTD PMID:26272509 epichlorohydrin increases expression ISO RGD:1319531 6480464 Epichlorohydrin results in increased expression of SLC7A11 mRNA CTD PMID:24211530 estriol increases expression ISO RGD:1319531 6480464 Estriol results in increased expression of SLC7A11 mRNA CTD PMID:15159206 estrone increases expression ISO RGD:1319531 6480464 Estrone results in increased expression of SLC7A11 mRNA CTD PMID:15159206 Ethyl acrylate decreases expression ISO RGD:1319531 6480464 ethyl acrylate results in decreased expression of SLC7A11 mRNA CTD PMID:26198647 ethyl methanesulfonate increases expression ISO RGD:1319531 6480464 Ethyl Methanesulfonate results in increased expression of SLC7A11 mRNA CTD PMID:23649840 ethylbenzene increases expression ISO RGD:1319531 6480464 ethylbenzene results in increased expression of SLC7A11 mRNA CTD PMID:20359517 eugenol increases expression ISO RGD:1319531 6480464 Eugenol results in increased expression of SLC7A11 mRNA CTD PMID:26198647 fluoranthene multiple interactions ISO RGD:1319532 6480464 [1-methylanthracene co-treated with fluoranthene] results in increased expression of SLC7A11 mRNA; more ... CTD PMID:28329830 fluoxetine increases expression ISO RGD:1319531 6480464 Fluoxetine results in increased expression of SLC7A11 mRNA CTD PMID:24356939 folic acid multiple interactions ISO RGD:1319532 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SLC7A11 mRNA CTD PMID:20938992 formaldehyde increases expression EXP 6480464 Formaldehyde results in increased expression of SLC7A11 mRNA CTD PMID:20884683 formaldehyde increases expression ISO RGD:1319531 6480464 Formaldehyde results in increased expression of SLC7A11 mRNA CTD PMID:23649840 gamma-hexachlorocyclohexane increases expression ISO RGD:1319531 6480464 Hexachlorocyclohexane results in increased expression of SLC7A11 mRNA CTD PMID:24356939 PMID:26198647 gedunin increases expression ISO RGD:1319531 6480464 gedunin results in increased expression of SLC7A11 mRNA CTD PMID:17010675 genistein decreases expression ISO RGD:1319531 6480464 Genistein results in decreased expression of SLC7A11 mRNA CTD PMID:16474171 glutathione increases abundance ISO RGD:1319532 6480464 SLC7A11 results in increased abundance of Glutathione CTD PMID:19015640 glutathione multiple interactions ISO RGD:1319531 6480464 [[[Bilirubin results in increased activity of [SLC7A11 protein co-treated with SLC3A2 protein]] which results in increased uptake of Cystine] which results in increased abundance of Glutathione] which results in decreased susceptibility to Hydrogen Peroxide; more ... CTD PMID:22216172 glutathione multiple interactions ISO RGD:1319532 6480464 [[Sulfasalazine results in decreased activity of SLC7A11 protein] which results in decreased abundance of Glutathione] which results in increased abundance of Reactive Oxygen Species; more ... CTD PMID:19015640 PMID:23085521 glycidol increases expression EXP 6480464 glycidol results in increased expression of SLC7A11 mRNA CTD PMID:24915197 hexamethylene diisocyanate increases expression ISO RGD:1319531 6480464 1,6-hexamethylene diisocyanate results in increased expression of SLC7A11 mRNA CTD PMID:24211530 hydrogen peroxide increases expression ISO RGD:1319531 6480464 Hydrogen Peroxide results in increased expression of SLC7A11 mRNA CTD PMID:12414654 hydrogen peroxide affects expression ISO RGD:1319531 6480464 Hydrogen Peroxide affects the expression of SLC7A11 mRNA CTD PMID:23410634 hydrogen peroxide multiple interactions ISO RGD:1319531 6480464 [[[Bilirubin results in increased activity of [SLC7A11 protein co-treated with SLC3A2 protein]] which results in increased uptake of Cystine] which results in increased abundance of Glutathione] which results in decreased susceptibility to Hydrogen Peroxide CTD PMID:22216172 hydrogen peroxide decreases expression ISO RGD:1319531 6480464 Hydrogen Peroxide results in decreased expression of SLC7A11 mRNA CTD PMID:18951874 hypochlorous acid increases expression ISO RGD:1319532 6480464 Hypochlorous Acid results in increased expression of SLC7A11 mRNA CTD PMID:19376150 ibuprofen increases expression ISO RGD:1319531 6480464 Ibuprofen results in increased expression of SLC7A11 mRNA CTD PMID:25596134 indometacin increases expression ISO RGD:1319531 6480464 Indomethacin results in increased expression of SLC7A11 mRNA CTD PMID:17401462 L-ascorbic acid increases expression ISO RGD:1319531 6480464 Ascorbic Acid results in increased expression of SLC7A11 mRNA CTD PMID:26198647 L-cystine multiple interactions ISO RGD:1319532 6480464 [SLC3A2 protein co-treated with SLC7A11 protein] results in increased uptake of Cystine; more ... CTD PMID:19576933 L-cystine multiple interactions ISO RGD:1319531 6480464 [[[Bilirubin results in increased activity of [SLC7A11 protein co-treated with SLC3A2 protein]] which results in increased uptake of Cystine] which results in increased abundance of Glutathione] which results in decreased susceptibility to Hydrogen Peroxide; more ... CTD PMID:22216172 L-methionine multiple interactions ISO RGD:1319532 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SLC7A11 mRNA CTD PMID:20938992 lead diacetate increases expression ISO RGD:1319532 6480464 lead acetate results in increased expression of SLC7A11 mRNA CTD PMID:25270620 lead diacetate increases expression ISO RGD:1319531 6480464 lead acetate results in increased expression of SLC7A11 mRNA CTD PMID:22839698 PMID:27562236 leflunomide increases expression ISO RGD:1319531 6480464 leflunomide results in increased expression of SLC7A11 mRNA CTD PMID:28988120 lipopolysaccharide multiple interactions ISO RGD:1319532 6480464 (+)-JQ1 compound inhibits the reaction [Lipopolysaccharides results in increased expression of SLC7A11 mRNA] CTD PMID:25890327 lipopolysaccharide increases expression ISO RGD:1319532 6480464 Lipopolysaccharides results in increased expression of SLC7A11 mRNA CTD PMID:25890327 MeIQx increases expression ISO RGD:1319531 6480464 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline results in increased expression of SLC7A11 mRNA CTD PMID:20816883 menadione increases expression ISO RGD:1319531 6480464 Vitamin K 3 results in increased expression of SLC7A11 mRNA CTD PMID:12414654 PMID:23410634 mercury dibromide increases expression ISO RGD:1319531 6480464 mercuric bromide results in increased expression of SLC7A11 mRNA CTD PMID:26272509 mercury dibromide multiple interactions ISO RGD:1319531 6480464 [NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLC7A11 mRNA CTD PMID:27188386 metformin increases expression EXP 6480464 Metformin results in increased expression of SLC7A11 mRNA CTD PMID:25596134 methamphetamine increases expression EXP 6480464 Methamphetamine results in increased expression of SLC7A11 mRNA CTD PMID:28619521 methotrexate decreases expression ISO RGD:1319531 6480464 Methotrexate results in decreased expression of SLC7A11 mRNA CTD PMID:19192274 methyl methacrylate increases expression ISO RGD:1319532 6480464 Methylmethacrylate results in increased expression of SLC7A11 mRNA CTD PMID:16916219 methylmercury chloride multiple interactions EXP 6480464 [methylmercuric chloride affects the localization of NFE2L2 protein] which results in increased expression of SLC7A11 mRNA CTD PMID:20421342 methylmercury chloride increases expression ISO RGD:1319531 6480464 methylmercuric chloride results in increased expression of SLC7A11 mRNA CTD PMID:23179753 more ... methylmercury chloride affects response to substance ISO RGD:1319531 6480464 SLC7A11 gene SNP affects the susceptibility to methylmercuric chloride CTD PMID:25622337 microcystin-LR increases expression ISO RGD:1319532 6480464 cyanoginosin LR results in increased expression of SLC7A11 mRNA CTD PMID:17654400 mitomycin C decreases expression ISO RGD:1319531 6480464 Mitomycin results in decreased expression of SLC7A11 mRNA CTD PMID:26198647 mono(2-ethylhexyl) phthalate increases expression ISO RGD:1319531 6480464 mono-(2-ethylhexyl)phthalate results in increased expression of SLC7A11 mRNA CTD PMID:24356939 motexafin gadolinium multiple interactions ISO RGD:1319531 6480464 [Zinc Acetate co-treated with motexafin gadolinium] affects the expression of SLC7A11 mRNA CTD PMID:16357179 motexafin gadolinium increases expression ISO RGD:1319531 6480464 motexafin gadolinium results in increased expression of SLC7A11 mRNA CTD PMID:16357179 mycophenolic acid decreases expression ISO RGD:1319531 6480464 Mycophenolic Acid results in decreased expression of SLC7A11 mRNA CTD PMID:24356939 N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Cocaine results in decreased expression of SLC7A11 protein] CTD PMID:19717140 N-acetyl-L-cysteine multiple interactions ISO RGD:1319531 6480464 Acetylcysteine inhibits the reaction [elesclomol results in increased expression of SLC7A11 mRNA] CTD PMID:18723479 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases expression ISO RGD:1319532 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SLC7A11 mRNA CTD PMID:25566086 N-methyl-4-phenylpyridinium increases expression ISO RGD:1319531 6480464 1-Methyl-4-phenylpyridinium results in increased expression of SLC7A11 mRNA CTD PMID:24810058 N-nitrosodimethylamine increases expression ISO RGD:1319531 6480464 Dimethylnitrosamine results in increased expression of SLC7A11 mRNA CTD PMID:26198647 naphthalene increases expression EXP 6480464 naphthalene analog results in increased expression of SLC7A11 mRNA CTD PMID:24976557 naphthalene-1,2-diol increases expression ISO RGD:1319531 6480464 1,2-dihydroxynaphthalene analog results in increased expression of SLC7A11 mRNA; more ... CTD PMID:25807370 nickel atom increases expression ISO RGD:1319531 6480464 Nickel results in increased expression of SLC7A11 mRNA CTD PMID:24768652 PMID:25583101 nickel dichloride affects expression EXP 6480464 nickel chloride affects the expression of SLC7A11 mRNA CTD PMID:22110744 nickel dichloride increases expression ISO RGD:1319531 6480464 nickel chloride results in increased expression of SLC7A11 mRNA CTD PMID:17312168 nickel sulfate increases expression ISO RGD:1319531 6480464 nickel sulfate results in increased expression of SLC7A11 mRNA CTD PMID:22714537 Nonylphenol increases expression ISO RGD:1319531 6480464 nonylphenol results in increased expression of SLC7A11 mRNA CTD PMID:15159206 o-xylene increases expression ISO RGD:1319531 6480464 2-xylene results in increased expression of SLC7A11 mRNA CTD PMID:20359517 ochratoxin A affects expression ISO RGD:1319531 6480464 ochratoxin A affects the expression of SLC7A11 mRNA CTD PMID:23824090 ozone increases expression ISO RGD:1319532 6480464 Ozone results in increased expression of SLC7A11 mRNA CTD PMID:17095637 ozone increases expression ISO RGD:1319531 6480464 Ozone results in increased expression of SLC7A11 mRNA CTD PMID:28652203 p-anisidine increases expression ISO RGD:1319531 6480464 4-anisidine results in increased expression of SLC7A11 mRNA CTD PMID:26198647 p-chloromercuribenzoic acid increases expression ISO RGD:1319531 6480464 p-Chloromercuribenzoic Acid results in increased expression of SLC7A11 mRNA CTD PMID:26272509 p-chloromercuribenzoic acid multiple interactions ISO RGD:1319531 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLC7A11 mRNA CTD PMID:27188386 panobinostat multiple interactions ISO RGD:1319531 6480464 [NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLC7A11 mRNA CTD PMID:27188386 panobinostat increases expression ISO RGD:1319531 6480464 panobinostat results in increased expression of SLC7A11 mRNA CTD PMID:26272509 para-Cresidine decreases expression ISO RGD:1319531 6480464 cresidine results in decreased expression of SLC7A11 mRNA CTD PMID:26198647 paracetamol affects expression ISO RGD:1319532 6480464 Acetaminophen affects the expression of SLC7A11 mRNA CTD PMID:17562736 paracetamol affects expression ISO RGD:1319531 6480464 Acetaminophen affects the expression of SLC7A11 mRNA CTD PMID:25458485 paracetamol increases expression ISO RGD:1319531 6480464 Acetaminophen results in increased expression of SLC7A11 mRNA CTD PMID:21420995 PMID:29067470 paraquat multiple interactions ISO RGD:1319531 6480464 [alpha-Tocopherol co-treated with Paraquat] results in increased expression of SLC7A11 mRNA; more ... CTD PMID:24530478 paraquat increases expression ISO RGD:1319532 6480464 Paraquat results in increased expression of SLC7A11 mRNA CTD PMID:23085521 paraquat multiple interactions ISO RGD:1319532 6480464 [SLC7A11 gene mutant form results in increased susceptibility to Paraquat] which results in decreased abundance of Glutathione CTD PMID:23085521 paraquat increases response to substance ISO RGD:1319532 6480464 SLC7A11 gene mutant form results in increased susceptibility to Paraquat CTD PMID:23085521 phenobarbital multiple interactions ISO RGD:1319532 6480464 NR1I3 protein affects the reaction [Phenobarbital results in increased expression of SLC7A11 mRNA] CTD PMID:19482888 phenobarbital increases expression ISO RGD:1319531 6480464 Phenobarbital results in increased expression of SLC7A11 mRNA CTD PMID:19084549 phenobarbital increases expression ISO RGD:1319532 6480464 Phenobarbital results in increased expression of SLC7A11 mRNA CTD PMID:19482888 phenol increases expression ISO RGD:1319531 6480464 Phenol results in increased expression of SLC7A11 mRNA CTD PMID:26198647 phenylmercury acetate increases expression ISO RGD:1319531 6480464 Phenylmercuric Acetate results in increased expression of SLC7A11 mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:1319531 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLC7A11 mRNA CTD PMID:27188386 phorbol 13-acetate 12-myristate increases expression ISO RGD:1319532 6480464 Tetradecanoylphorbol Acetate results in increased expression of SLC7A11 mRNA CTD PMID:17200146 phorbol 13-acetate 12-myristate increases expression ISO RGD:1319531 6480464 Tetradecanoylphorbol Acetate results in increased expression of SLC7A11 mRNA CTD PMID:17200146 PMID:26198647 piroxicam decreases expression ISO RGD:1319531 6480464 Piroxicam results in decreased expression of SLC7A11 mRNA CTD PMID:19192274 potassium dichromate increases expression ISO RGD:1319532 6480464 Potassium Dichromate results in increased expression of SLC7A11 mRNA CTD PMID:23608068 prednisolone decreases expression ISO RGD:1319531 6480464 Prednisolone results in decreased expression of SLC7A11 mRNA CTD PMID:19192274 prednisolone increases expression ISO RGD:1319531 6480464 Prednisolone results in increased expression of SLC7A11 mRNA CTD PMID:24356939 progesterone increases expression ISO RGD:1319531 6480464 Progesterone results in increased expression of SLC7A11 mRNA CTD PMID:18037150 propofol decreases expression EXP 6480464 Propofol results in decreased expression of SLC7A11 protein CTD PMID:28663055 propofol multiple interactions EXP 6480464 alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid inhibits the reaction [Propofol results in decreased expression of SLC7A11 protein] CTD PMID:28663055 quercetin increases expression ISO RGD:1319531 6480464 Quercetin results in increased expression of SLC7A11 mRNA CTD PMID:21632981 PMID:26198647 raloxifene increases expression ISO RGD:1319531 6480464 Raloxifene Hydrochloride results in increased expression of SLC7A11 mRNA CTD PMID:16497877 reactive oxygen species multiple interactions ISO RGD:1319532 6480464 [[Sulfasalazine results in decreased activity of SLC7A11 protein] which results in decreased abundance of Glutathione] which results in increased abundance of Reactive Oxygen Species; more ... CTD PMID:19015640 resorcinol decreases expression ISO RGD:1319531 6480464 resorcinol results in decreased expression of SLC7A11 mRNA CTD PMID:22623647 PMID:26198647 SB 203580 multiple interactions ISO RGD:1319532 6480464 SB 203580 inhibits the reaction [[1-methylanthracene co-treated with fluoranthene] results in increased expression of SLC7A11 mRNA] CTD PMID:28329830 SB 431542 multiple interactions ISO RGD:1319531 6480464 [NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLC7A11 mRNA; more ... CTD PMID:27188386 selenium atom increases import ISO RGD:1319531 6480464 SLC7A11 mRNA results in increased import of Selenium CTD PMID:28070112 silicon dioxide increases expression ISO RGD:1319532 6480464 Silicon Dioxide results in increased expression of SLC7A11 mRNA CTD PMID:19073995 silver atom increases expression ISO RGD:1319531 6480464 Silver results in increased expression of SLC7A11 mRNA CTD PMID:26014281 PMID:28959546 silver atom increases expression ISO RGD:1319532 6480464 Silver results in increased expression of SLC7A11 mRNA CTD PMID:27131904 silver(0) increases expression ISO RGD:1319531 6480464 Silver results in increased expression of SLC7A11 mRNA CTD PMID:26014281 PMID:28959546 silver(0) increases expression ISO RGD:1319532 6480464 Silver results in increased expression of SLC7A11 mRNA CTD PMID:27131904 silver(1+) increases expression ISO RGD:1319532 6480464 Silver results in increased expression of SLC7A11 mRNA CTD PMID:27131904 silver(1+) increases expression ISO RGD:1319531 6480464 Silver results in increased expression of SLC7A11 mRNA CTD PMID:26014281 PMID:28959546 sodium arsenite increases expression ISO RGD:1319531 6480464 sodium arsenite results in increased expression of SLC7A11 mRNA CTD PMID:20886546 more ... sodium arsenite increases expression ISO RGD:1319532 6480464 sodium arsenite results in increased expression of SLC7A11 CTD PMID:29204679 sodium arsenite affects methylation ISO RGD:1319531 6480464 sodium arsenite affects the methylation of SLC7A11 gene CTD PMID:28589171 sodium aurothiomalate decreases expression ISO RGD:1319531 6480464 Gold Sodium Thiomalate results in decreased expression of SLC7A11 mRNA CTD PMID:19192274 sodium dichromate affects expression EXP 6480464 sodium bichromate affects the expression of SLC7A11 mRNA CTD PMID:22110744 sodium fluoride decreases expression EXP 6480464 Sodium Fluoride results in decreased expression of SLC7A11 mRNA CTD PMID:27257137 succimer multiple interactions ISO RGD:1319532 6480464 [Succimer binds to Magnetite Nanoparticles] which results in increased expression of SLC7A11 mRNA; more ... CTD PMID:21641980 PMID:26378955 succimer multiple interactions ISO RGD:1319531 6480464 [Succimer co-treated with Magnetite Nanoparticles] results in increased expression of SLC7A11 mRNA CTD PMID:26378955 sulfasalazine decreases activity ISO RGD:1319531 6480464 Sulfasalazine results in decreased activity of SLC7A11 protein CTD PMID:20007406 sulfasalazine multiple interactions ISO RGD:1319532 6480464 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[Sulfasalazine results in decreased activity of SLC7A11 protein] which results in increased expression of CAV1 mRNA]; more ... CTD PMID:19015640 PMID:19576933 sulfasalazine decreases activity ISO RGD:1319532 6480464 Sulfasalazine results in decreased activity of SLC7A11 protein CTD PMID:19015640 tert-butyl hydroperoxide increases expression ISO RGD:1319531 6480464 tert-Butylhydroperoxide results in increased expression of SLC7A11 mRNA CTD PMID:12414654 PMID:23410634 tetrachloromethane increases expression ISO RGD:1319532 6480464 Carbon Tetrachloride results in increased expression of SLC7A11 mRNA CTD PMID:27339419 tetraphene decreases expression ISO RGD:1319532 6480464 benz(a)anthracene results in decreased expression of SLC7A11 mRNA CTD PMID:26377693 tetrathiomolybdate(2-) increases expression ISO RGD:1319531 6480464 tetrathiomolybdate analog results in increased expression of SLC7A11 mRNA CTD PMID:19323979 thiram increases expression ISO RGD:1319531 6480464 Thiram results in increased expression of SLC7A11 mRNA CTD PMID:24211530 titanium dioxide increases expression EXP 6480464 titanium dioxide results in increased expression of SLC7A11 mRNA CTD PMID:30012374 toluene increases expression ISO RGD:1319531 6480464 Toluene results in increased expression of SLC7A11 mRNA CTD PMID:20359517 PMID:28245982 Tributyltin oxide decreases expression ISO RGD:1319531 6480464 bis(tri-n-butyltin)oxide results in decreased expression of SLC7A11 mRNA CTD PMID:26198647 trichloroethene increases expression ISO RGD:1319531 6480464 Trichloroethylene results in increased expression of SLC7A11 mRNA CTD PMID:20359517 trichostatin A increases expression ISO RGD:1319531 6480464 trichostatin A results in increased expression of SLC7A11 mRNA CTD PMID:24935251 PMID:26272509 trichostatin A multiple interactions ISO RGD:1319531 6480464 [NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLC7A11 mRNA CTD PMID:27188386 trimellitic anhydride increases expression ISO RGD:1319532 6480464 trimellitic anhydride results in increased expression of SLC7A11 mRNA CTD PMID:19042947 tris(2-butoxyethyl) phosphate affects expression ISO RGD:1319531 6480464 tris(2-butoxyethyl) phosphate affects the expression of SLC7A11 mRNA CTD PMID:29024780 tunicamycin increases expression ISO RGD:1319532 6480464 Tunicamycin results in increased expression of SLC7A11 mRNA CTD PMID:17127020 urethane increases expression ISO RGD:1319531 6480464 Urethane results in increased expression of SLC7A11 mRNA CTD PMID:28818685 valproic acid affects expression ISO RGD:1319531 6480464 Valproic Acid affects the expression of SLC7A11 mRNA CTD PMID:25979313 valproic acid affects splicing EXP 6480464 Valproic Acid affects the splicing of SLC7A11 mRNA CTD PMID:29427782 valproic acid multiple interactions ISO RGD:1319531 6480464 [NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLC7A11 mRNA CTD PMID:27188386 valproic acid increases expression ISO RGD:1319531 6480464 Valproic Acid results in increased expression of SLC7A11 mRNA CTD PMID:23179753 more ... valproic acid decreases expression ISO RGD:1319532 6480464 Valproic Acid results in decreased expression of SLC7A11 mRNA CTD PMID:24896083 vanillin increases expression ISO RGD:1319531 6480464 vanillin results in increased expression of SLC7A11 mRNA CTD PMID:17178418 vincristine increases expression ISO RGD:1319531 6480464 Vincristine results in increased expression of SLC7A11 mRNA CTD PMID:23649840 vitamin E multiple interactions ISO RGD:1319531 6480464 [alpha-Tocopherol co-treated with Paraquat] results in increased expression of SLC7A11 mRNA; more ... CTD PMID:24530478 vorinostat multiple interactions ISO RGD:1319531 6480464 [NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLC7A11 mRNA CTD PMID:27188386 vorinostat increases expression ISO RGD:1319531 6480464 vorinostat results in increased expression of SLC7A11 mRNA CTD PMID:26272509 zearalenone increases expression ISO RGD:1319531 6480464 Zearalenone results in increased expression of SLC7A11 mRNA CTD PMID:25424538 zinc acetate multiple interactions ISO RGD:1319531 6480464 [Zinc Acetate co-treated with motexafin gadolinium] affects the expression of SLC7A11 mRNA CTD PMID:16357179 zinc acetate increases expression ISO RGD:1319531 6480464 Zinc Acetate results in increased expression of SLC7A11 mRNA CTD PMID:16357179 zinc atom multiple interactions ISO RGD:1319531 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of SLC7A11 mRNA CTD PMID:18593933 zinc(0) multiple interactions ISO RGD:1319531 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of SLC7A11 mRNA CTD PMID:18593933
Biological Process adult behavior IEA UniProtKB:Q9WTR6|ensembl:ENSMUSP00000029297 1600115 GO_REF:0000107 Ensembl GO_REF:0000107 adult behavior ISO RGD:1319532 1624291 RGD MGI:MGI:6114361 PMID:29024663 brain development IEP 2315030 RGD brain development ISO RGD:1319532 1624291 MGI:MGI:1857061 RGD MGI:MGI:3664848 PMID:17035536 cellular response to oxidative stress IEA UniProtKB:Q9WTR6|ensembl:ENSMUSP00000029297 1600115 GO_REF:0000107 Ensembl GO_REF:0000107 cellular response to oxidative stress ISO RGD:1319532 1624291 MGI:MGI:3608695 RGD MGI:MGI:5469541 PMID:23085521 dipeptide import across plasma membrane IEA UniProtKB:Q9WTR6|ensembl:ENSMUSP00000029297 1600115 GO_REF:0000107 Ensembl GO_REF:0000107 dipeptide import across plasma membrane ISO RGD:1319532 1624291 MGI:MGI:1857061 RGD MGI:MGI:3588610 PMID:16037214 glutamate homeostasis IEA UniProtKB:Q9WTR6|ensembl:ENSMUSP00000029297 1600115 GO_REF:0000107 Ensembl GO_REF:0000107 glutamate homeostasis ISO RGD:1319532 1624291 MGI:MGI:1351339|MGI:MGI:3608695 RGD MGI:MGI:4947188 more ... glutathione metabolic process IEA UniProtKB:Q9WTR6|ensembl:ENSMUSP00000029297 1600115 GO_REF:0000107 Ensembl GO_REF:0000107 glutathione metabolic process ISO RGD:1319532 1624291 MGI:MGI:3608695 RGD MGI:MGI:3710059 more ... glutathione transmembrane transport IEA UniProtKB:Q9WTR6|ensembl:ENSMUSP00000029297 1600115 GO_REF:0000107 Ensembl GO_REF:0000107 glutathione transmembrane transport ISO RGD:1319532 1624291 RGD MGI:MGI:3664848 PMID:17035536 L-glutamate import across plasma membrane IEA UniProtKB:Q9WTR6|ensembl:ENSMUSP00000029297 1600115 GO_REF:0000107 Ensembl GO_REF:0000107 L-glutamate import across plasma membrane ISO RGD:1319532 1624291 MGI:MGI:3608695 RGD MGI:MGI:4948153 PMID:21490221 lens fiber cell differentiation IEP 2315033 RGD limb development IEA UniProtKB:Q9WTR6|ensembl:ENSMUSP00000029297 1600115 GO_REF:0000107 Ensembl GO_REF:0000107 limb development ISO RGD:1319532 1624291 MGI:MGI:3608695 RGD MGI:MGI:4948153 PMID:21490221 lung alveolus development IEA UniProtKB:Q9WTR6|ensembl:ENSMUSP00000029297 1600115 GO_REF:0000107 Ensembl GO_REF:0000107 lung alveolus development ISO RGD:1319532 1624291 MGI:MGI:3608695 RGD MGI:MGI:5469541 PMID:23085521 modulation of chemical synaptic transmission IEA UniProtKB:Q9WTR6|ensembl:ENSMUSP00000029297 1600115 GO_REF:0000107 Ensembl GO_REF:0000107 modulation of chemical synaptic transmission ISO RGD:1319532 1624291 MGI:MGI:3608695 RGD MGI:MGI:5616960 PMID:25429150 negative regulation of oxidative stress-induced neuron death IEA UniProtKB:Q9WTR6|ensembl:ENSMUSP00000029297 1600115 GO_REF:0000107 Ensembl GO_REF:0000107 negative regulation of oxidative stress-induced neuron death ISO RGD:1319532 1624291 MGI:MGI:1857061 RGD MGI:MGI:3664848 PMID:17035536 organic substance transport ISO RGD:1319532 1624291 MGI:MGI:1857061|MGI:MGI:3608695 RGD MGI:MGI:3588610 more ... platelet aggregation ISO RGD:1319532 1624291 MGI:MGI:1857061 RGD MGI:MGI:79102 PMID:8699821 platelet aggregation IEA UniProtKB:Q9WTR6|ensembl:ENSMUSP00000029297 1600115 GO_REF:0000107 Ensembl GO_REF:0000107 regulation of AMPA glutamate receptor clustering IEA UniProtKB:Q9WTR6|ensembl:ENSMUSP00000029297 1600115 GO_REF:0000107 Ensembl GO_REF:0000107 regulation of AMPA glutamate receptor clustering ISO RGD:1319532 1624291 MGI:MGI:3608695 RGD MGI:MGI:5616960 PMID:25429150 regulation of cell population proliferation IEA UniProtKB:Q9WTR6|ensembl:ENSMUSP00000029297 1600115 GO_REF:0000107 Ensembl GO_REF:0000107 regulation of cell population proliferation ISO RGD:1319532 1624291 MGI:MGI:1857061 RGD MGI:MGI:3588610 more ... regulation of cellular response to oxidative stress ISO RGD:1319532 1624291 MGI:MGI:1857061 RGD MGI:MGI:3588610 PMID:16037214 regulation of cysteine metabolic process IEA UniProtKB:Q9WTR6|ensembl:ENSMUSP00000029297 1600115 GO_REF:0000107 Ensembl GO_REF:0000107 regulation of cysteine metabolic process ISO RGD:1319532 1624291 MGI:MGI:3608695 RGD MGI:MGI:3710059 PMID:17200146 regulation of glutamate metabolic process IEA UniProtKB:Q9WTR6|ensembl:ENSMUSP00000029297 1600115 GO_REF:0000107 Ensembl GO_REF:0000107 regulation of glutamate metabolic process ISO RGD:1319532 1624291 MGI:MGI:3608695 RGD MGI:MGI:4948153 more ... regulation of glutathione biosynthetic process IEA UniProtKB:Q9WTR6|ensembl:ENSMUSP00000029297 1600115 GO_REF:0000107 Ensembl GO_REF:0000107 regulation of glutathione biosynthetic process ISO RGD:1319532 1624291 MGI:MGI:1857061 RGD MGI:MGI:3588610 PMID:16037214 regulation of melanin biosynthetic process IEA UniProtKB:Q9WTR6|ensembl:ENSMUSP00000029297 1600115 GO_REF:0000107 Ensembl GO_REF:0000107 regulation of melanin biosynthetic process ISO RGD:1319532 1624291 MGI:MGI:1857061 RGD MGI:MGI:3588610 PMID:16037214 regulation of neutrophil apoptotic process IEA UniProtKB:Q9WTR6|ensembl:ENSMUSP00000029297 1600115 GO_REF:0000107 Ensembl GO_REF:0000107 regulation of neutrophil apoptotic process ISO RGD:1319532 1624291 MGI:MGI:3608695 RGD MGI:MGI:3710059 PMID:17200146 regulation of protein transport IEA UniProtKB:Q9WTR6|ensembl:ENSMUSP00000029297 1600115 GO_REF:0000107 Ensembl GO_REF:0000107 regulation of protein transport ISO RGD:1319532 1624291 MGI:MGI:1857061 RGD MGI:MGI:3588610 PMID:16037214 regulation of synapse organization ISO RGD:1319532 1624291 MGI:MGI:3608695 RGD MGI:MGI:5616960 PMID:25429150 response to nicotine IEP 2315027 RGD response to organic cyclic compound IEA UniProtKB:Q9WTR6|ensembl:ENSMUSP00000029297 1600115 GO_REF:0000107 Ensembl GO_REF:0000107 response to organic cyclic compound ISO RGD:1319532 1624291 MGI:MGI:3608695 RGD MGI:MGI:4947188 PMID:21191088 response to oxidative stress IEP 2315032 RGD response to redox state IEA UniProtKB:Q9WTR6|ensembl:ENSMUSP00000029297 1600115 GO_REF:0000107 Ensembl GO_REF:0000107 response to redox state ISO RGD:1319532 1624291 MGI:MGI:3608695 RGD MGI:MGI:3608215 PMID:16144837 response to toxic substance ISO RGD:1319531 1624291 RGD PMID:17575980 striatum development IEA UniProtKB:Q9WTR6|ensembl:ENSMUSP00000029297 1600115 GO_REF:0000107 Ensembl GO_REF:0000107 striatum development ISO RGD:1319532 1624291 MGI:MGI:1857061 RGD MGI:MGI:3664848 PMID:17035536 ventricular system development IEA UniProtKB:Q9WTR6|ensembl:ENSMUSP00000029297 1600115 GO_REF:0000107 Ensembl GO_REF:0000107 ventricular system development ISO RGD:1319532 1624291 MGI:MGI:1857061 RGD MGI:MGI:3664848 PMID:17035536 visual learning IEA UniProtKB:Q9WTR6|ensembl:ENSMUSP00000029297 1600115 GO_REF:0000107 Ensembl GO_REF:0000107 visual learning ISO RGD:1319532 1624291 MGI:MGI:3608695 RGD MGI:MGI:4948153 more ... Cellular Component astrocyte projection IEA UniProtKB:Q9WTR6|ensembl:ENSMUSP00000029297 1600115 GO_REF:0000107 Ensembl GO_REF:0000107 astrocyte projection ISO RGD:1319532 1624291 RGD MGI:MGI:3624070 PMID:16399997 brush border membrane IEA UniProtKB:Q9WTR6|ensembl:ENSMUSP00000029297 1600115 GO_REF:0000107 Ensembl GO_REF:0000107 brush border membrane ISO RGD:1319532 1624291 RGD MGI:MGI:3624070 PMID:16399997 cell surface ISO RGD:1319531 1624291 RGD PMID:25063885 cell surface IEA UniProtKB:Q9UPY5|ensembl:ENSP00000280612 1600115 GO_REF:0000107 Ensembl GO_REF:0000107 cytoskeleton IDA 2315030 RGD integral component of membrane IEA UniProtKB-KW:KW-0812 1600115 GO_REF:0000038 UniProt GO_REF:0000038 intracellular membrane-bounded organelle IDA 2315030 RGD membrane ISO RGD:1319532 1624291 RGD MGI:MGI:6144334 PMID:29350434 plasma membrane IDA 2315030 RGD rough endoplasmic reticulum IDA 2315030 RGD Molecular Function L-amino acid transmembrane transporter activity IBA MGI:MGI:1298205|MGI:MGI:1355323|PANTHER:PTN000208507|WB:WBGene00000002 13792537 PMID:21873635 GO_Central molecular_function ND 1598407 12/2009: no relevant rat data RGD protein binding ISO RGD:1319531 1624291 UniProtKB:P16070 RGD PMID:21397861
Gene-Chemical Interaction Annotations
