Adipoq (adiponectin, C1Q and collagen domain containing) - Rat Genome Database

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Gene: Adipoq (adiponectin, C1Q and collagen domain containing) Rattus norvegicus
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Symbol: Adipoq
Name: adiponectin, C1Q and collagen domain containing
RGD ID: 628748
Description: Enables identical protein binding activity. Involved in several processes, including cellular response to organonitrogen compound; positive regulation of glycogen (starch) synthase activity; and positive regulation of protein phosphorylation. Located in extracellular space. Part of protein-containing complex. Used to study brain infarction. Biomarker of several diseases, including end stage renal disease; fatty liver disease (multiple); glucose metabolism disease (multiple); hyperthyroidism; and obesity. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); cardiovascular system disease (multiple); non-alcoholic fatty liver disease; primary open angle glaucoma; and type 2 diabetes mellitus. Orthologous to human ADIPOQ (adiponectin, C1Q and collagen domain containing); PARTICIPATES IN adiponectin signaling pathway; eicosanoid signaling pathway via peroxisome proliferator-activated receptor gamma; type 2 diabetes mellitus pathway; INTERACTS WITH (+)-catechin; (+)-schisandrin B; (R)-adrenaline.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Acdc; Acrp30; Adid; adipocyte complement related protein of 30 kDa; adiponectin; adiponectin d
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: Adipoqm1Mcwi   Adipoqm2Mcwi   Adipoqm3Mcwi   Adipoqem1Mcwi   Adipoqem2Mcwi  
Genetic Models: FHH-Adipoqm3Mcwi FHH-Adipoqm2Mcwi FHH-Adipoqm1Mcwi SS-Adipoqem1Mcwi SS-Adipoqem2Mcwi
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21177,721,912 - 77,735,644 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1177,721,912 - 77,735,564 (-)Ensembl
Rnor_6.01181,330,845 - 81,344,488 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1181,330,293 - 81,344,488 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01184,363,940 - 84,382,663 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41179,908,291 - 79,911,065 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11179,965,888 - 79,968,654 (-)NCBI
Celera1176,596,543 - 76,599,824 (-)NCBICelera
Cytogenetic Map11q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
3MC syndrome 1  (ISO)
Acute Lung Injury  (ISO)
Alcoholic Fatty Liver  (ISO)
Alzheimer's disease  (ISO)
amyloidosis  (ISO)
ankylosing spondylitis  (ISO)
asthma  (ISO)
atherosclerosis  (ISO)
autoimmune hepatitis  (ISO)
Behcet's disease  (ISO)
biliary atresia  (ISO)
bipolar disorder  (ISO)
brain infarction  (IDA)
breast cancer  (ISO)
cardiomyopathy  (ISO)
cardiovascular system disease  (ISO)
Chemical and Drug Induced Liver Injury  (ISO)
Choroidal Neovascularization  (IDA,IEP,ISO)
Chronic Hepatitis C  (ISO)
chronic obstructive pulmonary disease  (ISO)
Cognitive Dysfunction  (ISO)
colitis  (IEP,ISO)
congestive heart failure  (ISO)
coronary aneurysm  (ISO)
coronary artery disease  (ISO)
Coronary Disease  (ISO)
coronary restenosis  (ISO)
Crohn's disease  (ISO)
dementia  (ISO)
diabetes mellitus  (ISO)
Diabetic Cardiomyopathies  (IEP)
Diabetic Foot  (ISO)
Diabetic Nephropathies  (ISO)
diabetic retinopathy  (ISO)
diffuse scleroderma  (ISO)
dry eye syndrome  (ISO)
end stage renal disease  (IEP,ISO)
Endotoxemia  (IEP)
Experimental Arthritis  (IEP,ISO)
Experimental Autoimmune Myocarditis  (ISO)
Experimental Diabetes Mellitus  (IEP,ISO)
Experimental Liver Cirrhosis  (ISO)
familial hyperlipidemia  (IEP)
familial Mediterranean fever  (ISO)
fatty liver disease  (IEP,ISO)
Fetal Growth Retardation  (IEP)
gestational diabetes  (IEP,ISO)
Graft vs Host Disease  (ISO)
Graves' disease  (ISO)
hepatocellular carcinoma  (ISO)
heroin dependence  (ISO)
HIV-Associated Lipodystrophy Syndrome  (ISO)
Human Viral Hepatitis  (ISO)
Huntington's disease  (ISO)
Hyperemia  (ISO)
hyperglycemia  (ISO)
hyperinsulinism  (IEP)
hypertension  (ISO)
hyperthyroidism  (IEP)
Hypertriglyceridemia  (ISO)
Hypoadiponectinemia  (ISO)
Inflammation  (ISO)
inflammatory bowel disease  (ISO)
Insulin Resistance  (IEP,ISO)
Jaundice  (ISO)
Kawasaki disease  (ISO)
Kidney Reperfusion Injury  (ISO)
Left Ventricular Hypertrophy  (ISO)
liver cirrhosis  (ISO)
Liver Reperfusion Injury  (IDA)
Mammary Neoplasms, Experimental  (IEP,ISO)
Masked Hypertension  (ISO)
Metabolic Syndrome  (ISO)
multiple sclerosis  (ISO)
Mycobacterium avium complex disease  (ISO)
myocardial infarction  (IEP)
Myocardial Ischemia  (ISO)
Myocardial Reperfusion Injury  (ISO)
myocarditis  (ISO)
non-alcoholic fatty liver disease  (IEP,ISO)
obesity  (IEP,ISO)
Oxygen-Induced Retinopathy  (ISO)
Perennial Allergic Rhinitis  (ISO)
peripheral artery disease  (ISO)
polycystic ovary syndrome  (ISO)
primary open angle glaucoma  (ISO)
proliferative diabetic retinopathy  (ISO)
prostate adenocarcinoma  (ISO)
pulmonary edema  (ISO)
pulmonary emphysema  (ISO)
pulmonary fibrosis  (ISO)
pulmonary hypertension  (ISO)
pulmonary tuberculosis  (ISO)
renal cell carcinoma  (ISO)
Reperfusion Injury  (IMP)
Rett syndrome  (ISO)
rheumatoid arthritis  (ISO)
Sepsis  (IEP,ISO)
sleep apnea  (ISO)
Spinal Cord Injuries  (ISO)
Stroke  (ISO)
Subarachnoid Hemorrhage  (ISO)
systemic lupus erythematosus  (ISO)
tongue squamous cell carcinoma  (ISO)
type 1 diabetes mellitus  (ISO)
type 2 diabetes mellitus  (IEP,ISO)
ulcerative colitis  (ISO)
vascular disease  (ISO)
visual epilepsy  (ISO)
Weight Gain  (ISO)
Weight Loss  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (EXP)
(+)-schisandrin B  (EXP)
(R)-adrenaline  (EXP)
(R)-carnitine  (EXP)
(R)-lipoic acid  (EXP)
15-deoxy-Delta(12,14)-prostaglandin J2  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17alpha-hydroxyprogesterone  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP,ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,2'-Dihydroxy-4-methoxybenzophenone  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-amino-2-deoxy-D-glucopyranose  (EXP,ISO)
2-butoxyethanol  (ISO)
2-deoxy-D-glucose  (ISO)
3',5'-cyclic AMP  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP,ISO)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,3',5-triiodo-L-thyronine  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-aminobenzamide  (EXP,ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4'-Methoxychalcone  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-methylumbelliferone  (ISO)
4-nonylphenol  (EXP)
5,6,7,8-tetrahydrobiopterin  (EXP)
5-(2-chloroethyl)-4-methylthiazole  (ISO)
[6]-Shogaol  (ISO)
acarbose  (EXP)
acetaldehyde  (ISO)
aflatoxin B1  (ISO)
AICA ribonucleotide  (EXP,ISO)
aldehydo-D-glucosamine  (EXP,ISO)
aldehydo-D-glucose  (EXP,ISO)
allopurinol  (EXP)
Aloe emodin  (ISO)
amlodipine  (ISO)
ammonium chloride  (EXP)
amphetamine  (EXP)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
atorvastatin calcium  (ISO)
avobenzone  (ISO)
benzamides  (ISO)
benzbromarone  (ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (ISO)
Benzyl parahydroxybenzoate  (ISO)
berberine  (ISO)
beta-carotene  (ISO)
beta-D-glucosamine  (EXP,ISO)
beta-hexachlorocyclohexane  (ISO)
bezafibrate  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
Bisphenol A diglycidyl ether  (ISO)
bongkrekic acid  (ISO)
boric acid  (ISO)
Butylbenzyl phthalate  (ISO)
Butylparaben  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
calcium silicate  (ISO)
candesartan  (ISO)
cannabidiol  (ISO)
capsaicin  (ISO)
capsazepine  (ISO)
carbon monoxide  (EXP)
carbon nanotube  (ISO)
carvacrol  (EXP)
carvedilol  (ISO)
cilazapril monohydrate  (ISO)
cimetidine  (ISO)
clozapine  (EXP,ISO)
cobalt dichloride  (ISO)
conjugated linoleic acid  (EXP,ISO)
copper atom  (EXP)
copper(0)  (EXP)
corticosterone  (ISO)
cortisol  (ISO)
cortisone  (ISO)
cucurbitacin B  (ISO)
cucurbitacin I  (EXP)
curcumin  (EXP,ISO)
cyclosporin A  (EXP)
cyproterone acetate  (ISO)
cytarabine  (ISO)
D-glucose  (EXP,ISO)
DDE  (ISO)
deoxycholic acid  (ISO)
Deoxycorticosterone acetate  (EXP)
dexamethasone  (EXP,ISO)
dexamethasone phosphate  (ISO)
diarsenic trioxide  (ISO)
dibenziodolium  (EXP,ISO)
dicamba  (ISO)
diethyl sulfate  (ISO)
diethylstilbestrol  (EXP)
dioxygen  (ISO)
disodium cromoglycate  (ISO)
disodium selenite  (ISO)
diuron  (EXP)
dorsomorphin  (EXP,ISO)
doxorubicin  (ISO)
efavirenz  (ISO)
Elemicin  (ISO)
enalapril  (ISO)
equilin  (ISO)
ethanol  (EXP,ISO)
ethylparaben  (ISO)
fenofibrate  (ISO)
flavonoids  (EXP)
fructooligosaccharide  (ISO)
fructose  (EXP,ISO)
furan  (EXP)
Ganoderic acid A  (ISO)
gemcitabine  (ISO)
geraniol  (EXP)
gingerol  (ISO)
ginsenoside Re  (ISO)
glucagon  (ISO)
glucose  (EXP,ISO)
glycine  (ISO)
graphite  (ISO)
GW 6471  (ISO)
GW 7647  (ISO)
hemin  (EXP)
hesperetin  (ISO)
hexadecanoic acid  (EXP,ISO)
hispidulin  (ISO)
hydrochlorothiazide  (ISO)
hydrogen peroxide  (ISO)
hydroxytyrosol  (ISO)
Indeno[1,2,3-cd]pyrene  (ISO)
indinavir  (ISO)
indometacin  (ISO)
iron dextran  (ISO)
isoflavones  (EXP)
lamivudine  (ISO)
lead diacetate  (EXP)
letrozole  (EXP)
levonorgestrel  (ISO)
linoleic acid  (ISO)
lipoic acid  (EXP)
lipopolysaccharide  (EXP,ISO)
liraglutide  (ISO)
lopinavir  (ISO)
losartan  (ISO)
lovastatin  (ISO)
LY294002  (EXP)
manganese(II) chloride  (EXP)
melatonin  (ISO)
Melengestrol acetate  (ISO)
mercury dichloride  (EXP)
metformin  (EXP,ISO)
methamphetamine  (ISO)
metronidazole  (ISO)
mifepristone  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
monocrotophos  (EXP)
monosodium L-glutamate  (ISO)
morin  (EXP)
Muraglitazar  (EXP)
N-acetyl-L-cysteine  (EXP)
naproxen  (ISO)
naringin  (ISO)
nelfinavir  (ISO)
neomycin  (ISO)
nevirapine  (ISO)
nicotinamide  (EXP,ISO)
nicotinic acid  (EXP,ISO)
nitrofen  (EXP)
Nonylphenol  (EXP,ISO)
norethisterone  (ISO)
norgestrel  (ISO)
nuarimol  (ISO)
octadecanoic acid  (ISO)
Octicizer  (ISO)
octocrylene  (ISO)
olanzapine  (ISO)
oleic acid  (EXP)
oleuropein  (EXP)
orientin  (ISO)
orlistat  (EXP,ISO)
oxybenzone  (ISO)
ozone  (EXP,ISO)
paraquat  (ISO)
paricalcitol  (ISO)
PCB138  (ISO)
pencycuron  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
Phenylamil  (ISO)
phloretin  (ISO)
phlorizin  (ISO)
phosphatidylcholine  (ISO)
picolinic acid  (EXP)
pioglitazone  (EXP,ISO)
piperine  (EXP)
pirinixic acid  (ISO)
pluronic P-123  (EXP)
Poloxamer  (EXP)
prednisone  (ISO)
prochloraz  (ISO)
progesterone  (ISO)
propylparaben  (ISO)
protein kinase inhibitor  (ISO)
quercetin  (EXP,ISO)
quinoxyfen  (ISO)
raffinose  (ISO)
raloxifene  (ISO)
ramipril  (ISO)
reactive oxygen species  (ISO)
resveratrol  (EXP,ISO)
retinyl acetate  (ISO)
rifampicin  (ISO)
rimonabant  (ISO)
risperidone  (ISO)
ritonavir  (ISO)
rotenone  (EXP)
Rutamarin  (ISO)
ruthenium red  (ISO)
salicylic acid  (EXP)
sapropterin  (EXP)
saquinavir  (ISO)
sarpogrelate  (ISO)
SB 203580  (EXP,ISO)
scopoletin  (EXP)
serpentine asbestos  (ISO)
sildenafil citrate  (EXP,ISO)
silicon dioxide  (ISO)
simvastatin  (EXP,ISO)
sodium arsenite  (ISO)
Sodium oleate  (ISO)
spironolactone  (EXP,ISO)
stavudine  (ISO)
stilben-4-ol  (ISO)
streptozocin  (EXP,ISO)
sulforaphane  (ISO)
tadalafil  (EXP)
telmisartan  (ISO)
Tesaglitazar  (EXP)
testosterone  (EXP,ISO)
tetrachloromethane  (EXP,ISO)
Thiocarbohydrazide  (ISO)
titanium dioxide  (ISO)
toluene  (ISO)
tolylfluanid  (ISO)
topiramate  (ISO)
triamcinolone  (ISO)
tributylstannane  (EXP,ISO)
trichloroethene  (ISO)
triclosan  (ISO)
triflumizole  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
troglitazone  (EXP,ISO)
tungsten  (ISO)
tunicamycin  (ISO)
umbelliferone  (ISO)
valproic acid  (ISO)
vanadium atom  (ISO)
vanadium(0)  (ISO)
vanadyl sulfate  (ISO)
vancomycin  (ISO)
vinclozolin  (EXP)
vitamin E  (EXP)
warfarin  (EXP)
XL147  (ISO)
zidovudine  (ISO)
zinc molecular entity  (EXP)
zinc protoporphyrin  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
brown fat cell differentiation  (ISO,ISS)
cellular response to cAMP  (IDA)
cellular response to epinephrine stimulus  (IDA)
cellular response to insulin stimulus  (IDA,ISO,ISS)
cellular response to xenobiotic stimulus  (ISO,ISS)
circadian rhythm  (IEP)
detection of oxidative stress  (ISO,ISS)
fatty acid beta-oxidation  (ISO,ISS)
fatty acid oxidation  (ISO,ISS,NAS)
gene expression  (ISO)
glucose homeostasis  (ISO,ISS)
glucose metabolic process  (ISO,ISS)
low-density lipoprotein particle clearance  (ISO,ISS)
negative regulation of blood pressure  (ISO,ISS)
negative regulation of cell migration  (ISO,ISS)
negative regulation of cold-induced thermogenesis  (ISO,ISS)
negative regulation of DNA biosynthetic process  (ISO,ISS)
negative regulation of DNA-templated transcription  (ISO,ISS)
negative regulation of ERK1 and ERK2 cascade  (ISO,ISS)
negative regulation of fat cell differentiation  (ISO,ISS)
negative regulation of gluconeogenesis  (ISO,ISS)
negative regulation of granulocyte differentiation  (ISO,ISS)
negative regulation of heterotypic cell-cell adhesion  (ISO,ISS)
negative regulation of hormone secretion  (IDA)
negative regulation of I-kappaB kinase/NF-kappaB signaling  (ISO,ISS)
negative regulation of inflammatory response  (ISO,ISS)
negative regulation of intracellular protein transport  (ISO,ISS)
negative regulation of low-density lipoprotein receptor activity  (ISO)
negative regulation of macrophage derived foam cell differentiation  (ISO,ISS)
negative regulation of macrophage differentiation  (ISO,ISS)
negative regulation of MAP kinase activity  (ISO,ISS)
negative regulation of metanephric mesenchymal cell migration  (ISO,ISS)
negative regulation of phagocytosis  (ISO,ISS)
negative regulation of platelet-derived growth factor receptor signaling pathway  (ISO,ISS)
negative regulation of platelet-derived growth factor receptor-alpha signaling pathway  (ISO,ISS)
negative regulation of protein autophosphorylation  (ISO,ISS)
negative regulation of receptor binding  (ISO,ISS)
negative regulation of synaptic transmission  (ISO,ISS)
negative regulation of tumor necrosis factor production  (ISO,ISS)
negative regulation of tumor necrosis factor-mediated signaling pathway  (ISO,ISS)
negative regulation of vascular associated smooth muscle cell migration  (ISO,ISS)
negative regulation of vascular associated smooth muscle cell proliferation  (ISO,ISS)
positive regulation of cAMP-dependent protein kinase activity  (ISO,ISS)
positive regulation of cholesterol efflux  (ISO,ISS)
positive regulation of cold-induced thermogenesis  (ISO,ISS)
positive regulation of fatty acid metabolic process  (ISO,ISS)
positive regulation of glucose import  (ISO,ISS)
positive regulation of glycogen (starch) synthase activity  (IDA)
positive regulation of I-kappaB kinase/NF-kappaB signaling  (ISO,ISS)
positive regulation of interleukin-8 production  (ISO,ISS)
positive regulation of lipid transporter activity  (ISO,ISS)
positive regulation of metanephric podocyte development  (ISO,ISS)
positive regulation of monocyte chemotactic protein-1 production  (ISO,ISS)
positive regulation of myeloid cell apoptotic process  (ISO,ISS)
positive regulation of peptidyl-tyrosine phosphorylation  (IDA)
positive regulation of protein kinase A signaling  (ISO,ISS)
positive regulation of protein kinase activity  (IDA)
positive regulation of protein phosphorylation  (ISO,ISS)
positive regulation of renal albumin absorption  (ISO,ISS)
positive regulation of signal transduction  (ISO,ISS)
protein localization to plasma membrane  (ISO,ISS)
regulation of glucose metabolic process  (ISO,ISS)
response to activity  (IEP)
response to bacterium  (ISO)
response to ethanol  (IEP)
response to glucocorticoid  (IEP)
response to glucose  (ISO,ISS)
response to hypoxia  (IEP)
response to linoleic acid  (IEP)
response to nutrient  (IEP)
response to nutrient levels  (IEP)
response to sucrose  (IEP)
response to tumor necrosis factor  (ISO,ISS)
response to xenobiotic stimulus  (IEP)
signal transduction  (IEA)

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. [Serum and synovial adiponectin, resistin, and visfatin levels in rheumatoid arthritis patients. Relation to disease activity]. Alkady EA, etal., Z Rheumatol. 2011 Sep;70(7):602-8.
2. The peroxisome proliferator-activated receptor gamma agonist rosiglitazone ameliorates murine lupus by induction of adiponectin. Aprahamian T, etal., J Immunol. 2009 Jan 1;182(1):340-6.
3. Effect of experimental hypo- and hyperthyroidism on serum adiponectin. Aragao CN, etal., Metabolism. 2007 Jan;56(1):6-11.
4. Adiponectin expression is decreased in the involved skin and sera of diffuse cutaneous scleroderma patients. Arakawa H, etal., Exp Dermatol. 2011 Sep;20(9):764-6. doi: 10.1111/j.1600-0625.2011.01310.x. Epub 2011 May 25.
5. Adiponectin and plant-derived mammalian adiponectin homolog exert a protective effect in murine colitis. Arsenescu V, etal., Dig Dis Sci. 2011 Oct;56(10):2818-32. Epub 2011 Apr 11.
6. Maternal docosahexaenoic acid increases adiponectin and normalizes IUGR-induced changes in rat adipose deposition. Bagley HN, etal., J Obes. 2013;2013:312153. doi: 10.1155/2013/312153. Epub 2013 Mar 6.
7. Adiponectin in outpatients with coronary artery disease: Independent predictors and relationship with heart failure. Baldasseroni S, etal., Nutr Metab Cardiovasc Dis. 2011 Oct 25.
8. Increased levels of adipokines in bipolar disorder. Barbosa IG, etal., J Psychiatr Res. 2011 Dec 2.
9. The cannabinoid CB1 receptor antagonist SR141716 increases Acrp30 mRNA expression in adipose tissue of obese fa/fa rats and in cultured adipocyte cells. Bensaid M, etal., Mol Pharmacol 2003 Apr;63(4):908-14.
10. Circadian profile of peripheral hormone levels in sprague-dawley rats and in common marmosets (Callithrix jacchus). Bertani S, etal., In Vivo. 2010 Nov-Dec;24(6):827-36.
11. Long-term plasma levels of leptin and adiponectin in Rett syndrome. Blardi P, etal., Clin Endocrinol (Oxf). 2009 May;70(5):706-9. Epub 2008 Aug 15.
12. Adiponectin expression in patients with inflammatory cardiomyopathy indicates favourable outcome and inflammation control. Bobbert P, etal., Eur Heart J. 2011 May;32(9):1134-47. Epub 2011 Jan 29.
13. Alcohol linked to enhanced angiogenesis in rat model of choroidal neovascularization. Bora PS, etal., FEBS J. 2006 Apr;273(7):1403-14.
14. Expression of adiponectin in choroidal tissue and inhibition of laser induced choroidal neovascularization by adiponectin. Bora PS, etal., FEBS Lett. 2007 May 15;581(10):1977-82. Epub 2007 Apr 20.
15. Analysis of serum adiponectin, resistin and leptin levels in children and adolescents with autoimmune thyroid disorders. Bossowski A, etal., J Pediatr Endocrinol Metab. 2010 Apr;23(4):369-77.
16. The adiponectin gene single-nucleotide polymorphism rs1501299 is associated with hepatocellular carcinoma risk. Cai X, etal., Clin Transl Oncol. 2014 Feb;16(2):166-72. doi: 10.1007/s12094-013-1056-7. Epub 2013 Jun 6.
17. Control of glycogen synthase through ADIPOR1-AMPK pathway in renal distal tubules of normal and diabetic rats. Cammisotto PG, etal., Am J Physiol Renal Physiol. 2008 Apr;294(4):F881-9. doi: 10.1152/ajprenal.00373.2007. Epub 2008 Feb 6.
18. Increased circulating adiponectin in males with chronic HCV hepatitis. Canavesi E, etal., Eur J Intern Med. 2015 Oct;26(8):635-9. doi: 10.1016/j.ejim.2015.08.001. Epub 2015 Aug 17.
19. Serum leptin, resistin, visfatin and adiponectin levels in tumor necrosis factor receptor-associated periodic syndrome (TRAPS). Cantarini L, etal., Clin Exp Rheumatol. 2012 May-Jun;30(3 Suppl 72):S108-14. Epub 2012 Sep 25.
20. Adiponectin protects against cerebral ischemia-reperfusion injury through anti-inflammatory action. Chen B, etal., Brain Res. 2009 Jun 1;1273:129-37. Epub 2009 Apr 9.
21. Serum adiponectin and leptin levels in Taiwanese breast cancer patients. Chen DC, etal., Cancer Lett. 2006 Jun 8;237(1):109-14. Epub 2005 Jul 12.
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PMID:19855092   PMID:19958641   PMID:20093130   PMID:20094971   PMID:20117976   PMID:20206399   PMID:20206611   PMID:20226796   PMID:20303976   PMID:20600433   PMID:20702148   PMID:20798331  
PMID:20838752   PMID:21176639   PMID:21357416   PMID:21441829   PMID:21536037   PMID:21557150   PMID:21733354   PMID:21784858   PMID:21868319   PMID:22127636   PMID:22562959   PMID:22575042  
PMID:22582096   PMID:22583869   PMID:22645452   PMID:22808905   PMID:22859860   PMID:22935137   PMID:22956308   PMID:23012479   PMID:23015294   PMID:23111552   PMID:23239819   PMID:23300647  
PMID:23376485   PMID:23392875   PMID:23478100   PMID:23497197   PMID:23667684   PMID:23756398   PMID:23842676   PMID:23867317   PMID:24289757   PMID:24913911   PMID:25065280   PMID:25099270  
PMID:25233838   PMID:25445438   PMID:25480577   PMID:25525608   PMID:25536648   PMID:25703252   PMID:25795513   PMID:25959017   PMID:26108677   PMID:26126515   PMID:26579573   PMID:26616727  
PMID:26639503   PMID:26715807   PMID:26731409   PMID:26823767   PMID:26845040   PMID:27068509   PMID:27923787   PMID:28033741   PMID:28051329   PMID:28219936   PMID:28387990   PMID:28542560  
PMID:28667102   PMID:28841247   PMID:28877872   PMID:28879415   PMID:29115380   PMID:29243095   PMID:29438632   PMID:29750888   PMID:29870775   PMID:30919218   PMID:31708912   PMID:32495657  
PMID:32566092   PMID:33271223   PMID:34307691   PMID:34588752   PMID:35720361  


Genomics

Comparative Map Data
Adipoq
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21177,721,912 - 77,735,644 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1177,721,912 - 77,735,564 (-)Ensembl
Rnor_6.01181,330,845 - 81,344,488 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1181,330,293 - 81,344,488 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01184,363,940 - 84,382,663 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41179,908,291 - 79,911,065 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11179,965,888 - 79,968,654 (-)NCBI
Celera1176,596,543 - 76,599,824 (-)NCBICelera
Cytogenetic Map11q23NCBI
ADIPOQ
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383186,842,710 - 186,858,463 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl3186,842,704 - 186,858,463 (+)EnsemblGRCh38hg38GRCh38
GRCh373186,560,499 - 186,576,252 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363188,043,157 - 188,058,946 (+)NCBINCBI36hg18NCBI36
Build 343188,043,164 - 188,058,952NCBI
Celera3184,996,682 - 185,012,474 (+)NCBI
Cytogenetic Map3q27.3NCBI
HuRef3183,969,546 - 183,985,186 (+)NCBIHuRef
CHM1_13186,523,992 - 186,539,778 (+)NCBICHM1_1
T2T-CHM13v2.03189,664,780 - 189,680,531 (+)NCBI
Adipoq
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391622,965,286 - 22,976,718 (+)NCBIGRCm39mm39
GRCm39 Ensembl1622,965,286 - 22,976,778 (+)Ensembl
GRCm381623,146,536 - 23,157,968 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1623,146,536 - 23,158,028 (+)EnsemblGRCm38mm10GRCm38
MGSCv371623,146,609 - 23,158,041 (+)NCBIGRCm37mm9NCBIm37
MGSCv361623,061,870 - 23,073,302 (+)NCBImm8
Celera1623,704,853 - 23,716,285 (+)NCBICelera
Cytogenetic Map16B1NCBI
cM Map1613.96NCBI
Adipoq
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542020,912,348 - 20,914,402 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542020,911,181 - 20,922,992 (-)NCBIChiLan1.0ChiLan1.0
ADIPOQ
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13192,341,471 - 192,354,885 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3192,341,320 - 192,354,885 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v03183,876,051 - 183,889,723 (+)NCBIMhudiblu_PPA_v0panPan3
ADIPOQ
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13419,398,310 - 19,410,519 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3419,354,825 - 19,409,844 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3423,492,088 - 23,493,907 (+)NCBI
ROS_Cfam_1.03419,309,590 - 19,321,861 (+)NCBI
ROS_Cfam_1.0 Ensembl3419,309,535 - 19,321,387 (+)Ensembl
UMICH_Zoey_3.13419,349,075 - 19,350,894 (+)NCBI
UNSW_CanFamBas_1.03419,348,981 - 19,350,799 (+)NCBI
UU_Cfam_GSD_1.03419,582,218 - 19,584,037 (+)NCBI
Adipoq
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602117,076,470 - 117,087,548 (-)NCBI
SpeTri2.0NW_0049365783,168,599 - 3,179,369 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADIPOQ
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13124,633,685 - 124,646,646 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113124,633,906 - 124,646,237 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213134,076,753 - 134,077,342 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ADIPOQ
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11581,128,427 - 81,142,779 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1581,129,795 - 81,147,391 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604154,621,772 - 54,634,568 (+)NCBIVero_WHO_p1.0
Adipoq
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473069,941,001 - 69,957,012 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462473069,941,963 - 69,959,266 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
AI176736  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21177,722,028 - 77,722,124 (+)MAPPERmRatBN7.2
Rnor_6.01181,330,962 - 81,331,057NCBIRnor6.0
Rnor_5.01184,364,057 - 84,364,152UniSTSRnor5.0
RGSC_v3.41327,240,254 - 27,240,348UniSTSRGSC3.4
RGSC_v3.41179,907,901 - 79,907,996UniSTSRGSC3.4
Celera1176,596,660 - 76,596,755UniSTS
RH 3.4 Map11643.5UniSTS
Cytogenetic Map11q23UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112767241082846715Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)112952841882566702Rat
2298551Neuinf10Neuroinflammation QTL 103.7nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)113123913478851519Rat
70180BpQTLcluster10Blood pressure QTL cluster 103.19arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)113491804179918041Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)114094618882566702Rat
2312566Glom20Glomerulus QTL 203.60.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)114428575982566702Rat
1581565Pur10Proteinuria QTL 100.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
1581572Uae35Urinary albumin excretion QTL 350.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)115445753486241447Rat
4889521Gluco62Glucose level QTL 622.820.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)115513672982993457Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)115635142486241447Rat
631506Bp104Blood pressure QTL 1042.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)115980279482566545Rat
70208Niddm22Non-insulin dependent diabetes mellitus QTL 223.61blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)115980279482566553Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)116034659086241447Rat
1549848Bvd6Brain ventricular dilatation QTL 63.10.0001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)116611332182169223Rat
634339Niddm50Non-insulin dependent diabetes mellitus QTL 503.32blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)116642214886241447Rat
1354593Stl12Serum triglyceride level QTL 123.36blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)116642214886241447Rat
1354656Bvd3Brain ventricular dilatation QTL 33.640.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)116944607082846715Rat
10450831Scl80Serum cholesterol level QTL 804.70.01blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)117695713183051965Rat


Genetic Models
This gene Adipoq is modified in the following models/strains
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:543
Count of miRNA genes:250
Interacting mature miRNAs:295
Transcripts:ENSRNOT00000002492
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 3 15 7 6 6 18 12 8 6
Low 1 40 42 41 12 41 2 5 74 17 29 3 2
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000002492   ⟹   ENSRNOP00000002492
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1177,721,912 - 77,735,564 (-)Ensembl
Rnor_6.0 Ensembl1181,330,845 - 81,344,488 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000089988   ⟹   ENSRNOP00000074467
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1177,722,433 - 77,735,564 (-)Ensembl
Rnor_6.0 Ensembl1181,330,293 - 81,334,120 (-)Ensembl
RefSeq Acc Id: NM_144744   ⟹   NP_653345
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21177,721,912 - 77,735,564 (-)NCBI
Rnor_6.01181,330,845 - 81,344,488 (-)NCBI
Rnor_5.01184,363,940 - 84,382,663 (-)NCBI
RGSC_v3.41179,908,291 - 79,911,065 (-)RGD
Celera1176,596,543 - 76,599,824 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039087986   ⟹   XP_038943914
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21177,721,912 - 77,735,644 (-)NCBI
Protein Sequences
Protein RefSeqs NP_653345 (Get FASTA)   NCBI Sequence Viewer  
  XP_038943914 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH92565 (Get FASTA)   NCBI Sequence Viewer  
  AAK61608 (Get FASTA)   NCBI Sequence Viewer  
  EDL78080 (Get FASTA)   NCBI Sequence Viewer  
  SOR70288 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_653345   ⟸   NM_144744
- Peptide Label: precursor
- UniProtKB: Q8K3R4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000074467   ⟸   ENSRNOT00000089988
RefSeq Acc Id: ENSRNOP00000002492   ⟸   ENSRNOT00000002492
RefSeq Acc Id: XP_038943914   ⟸   XM_039087986
- Peptide Label: isoform X1
Protein Domains
C1q

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8K3R4-F1-model_v2 AlphaFold Q8K3R4 1-244 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698244
Promoter ID:EPDNEW_R8769
Type:multiple initiation site
Name:Adipoq_1
Description:adiponectin, C1Q and collagen domain containing
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01181,344,461 - 81,344,521EPDNEW

Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:628748 AgrOrtholog
BioCyc Gene G2FUF-20858 BioCyc
Ensembl Genes ENSRNOG00000001821 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000002492 ENTREZGENE
  ENSRNOP00000002492.3 UniProtKB/TrEMBL
  ENSRNOP00000074467 ENTREZGENE
  ENSRNOP00000074467.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000002492 ENTREZGENE
  ENSRNOT00000002492.6 UniProtKB/TrEMBL
  ENSRNOT00000089988 ENTREZGENE
  ENSRNOT00000089988.2 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.40 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7308618 IMAGE-MGC_LOAD
InterPro Adiponectin UniProtKB/TrEMBL
  C1q UniProtKB/TrEMBL
  Collagen UniProtKB/TrEMBL
  Tumour_necrosis_fac-like UniProtKB/TrEMBL
KEGG Report rno:246253 UniProtKB/TrEMBL
MGC_CLONE MGC:108583 IMAGE-MGC_LOAD
NCBI Gene 246253 ENTREZGENE
PANTHER PTHR15427:SF20 UniProtKB/TrEMBL
Pfam C1q UniProtKB/TrEMBL
  Collagen UniProtKB/TrEMBL
PharmGKB ADIPOQ RGD
PhenoGen Adipoq PhenoGen
PRINTS COMPLEMNTC1Q UniProtKB/TrEMBL
PROSITE C1Q UniProtKB/TrEMBL
SMART C1Q UniProtKB/TrEMBL
Superfamily-SCOP TNF_like UniProtKB/TrEMBL
UniProt A0A0G2K845_RAT UniProtKB/TrEMBL
  Q8K3R4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Adipoq  adiponectin, C1Q and collagen domain containing  Acdc  adipocyte complement related protein of 30 kDa  Symbol and Name updated 1299863 APPROVED
2004-09-10 Acdc  adipocyte complement related protein of 30 kDa  Acrp30    Symbol and Name updated 1299863 APPROVED
2003-02-27 Acrp30  adipocyte complement related protein of 30 kDa      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_regulation expression in adipose tissue is induced by the cannabinoid receptor antagonist SR141716 632491