Strain Report - Rat Genome Database

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Strain: SHR-Cfbem1Tja

Symbol: SHR-Cfbem1Tja
Strain: SHR-Cfbem1
Substrain: Tja
RGD ID: 127285404
Citation ID: RRID:RGD_127285404
Ontology ID: RS:0004957
Alleles: Cfbem1Tja
Previously known as: Cfb-/-
Type: mutant
Source: Centre for Genomic and Experimental Medicine, MRC Institute for Genetics and Molecular Medicine, Edinburgh, United Kingdom
Origin: This strain was produced by injecting ZFNs targeting exon 6 of rat complement factor b (Cfb) (target sequence: CCCCTCGGGCTCCATGaatatcTACATGGTGCTGGATG),into SHR/NCrl rat embryos. The resulting mutation is a 19-bp deletion.
Last Known Status: Unknown
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2203,970,643 - 3,976,510RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0204,536,206 - 4,542,073RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0206,616,005 - 6,621,872RGD_MAPPER_PIPELINERnor5.0


References - curated
# Reference Title Reference Citation
1. Complement Factor B Is a Determinant of Both Metabolic and Cardiovascular Features of Metabolic Syndrome. Coan PM, etal., Hypertension. 2017 Jul 24. pii: HYPERTENSIONAHA.117.09242. doi: 10.1161/HYPERTENSIONAHA.117.09242.


Additional Information