Strain Report - Rat Genome Database

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Strain: TM-Prkdcem4KyoIl2rgem5Kyo

Symbol: TM-Prkdcem4KyoIl2rgem5Kyo
Strain: TM-Prkdcem4Il2rgem5
Substrain: Kyo
RGD ID: 11040950
Citation ID: RRID:RGD_11040950
Ontology ID: RS:0004141
Alleles: Il2rg;   Il2rgem5Kyo;   Prkdcem4Kyo;   Prkdc
Previously known as: TM-Prkdcem4KyoIl2rgem5Kyo; TM-DSCID; NBRP Rat No: 0648
Type: mutant
Source: National BioResource Project for the Rat in Japan
Origin: This strain was established by Zinc-finger nucleases (ZFNs) method causing 20-bp deletion in the exon1 of Prkdc gene and a 653-bp deletion Il2rg gene. Background strain: TM/Kyo
Coat Color: Albino
Last Known Status: Cryopreserved Sperm (as of 2017-07-12)
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21185,040,790 - 85,258,357RGD_MAPPER_PIPELINEmRatBN7.2
mRatBN7.2X66,395,330 - 66,399,026RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0X71,165,378 - 71,169,078RGD_MAPPER_PIPELINERnor6.0
Rnor_6.01189,293,547 - 89,510,948RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01192,347,175 - 92,565,022RGD_MAPPER_PIPELINERnor5.0
Rnor_5.0X72,017,856 - 72,021,516RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41186,951,420 - 87,169,229RGD_MAPPER_PIPELINERGSC3.4
RGSC_v3.4X89,342,055 - 89,345,715RGD_MAPPER_PIPELINERGSC3.4


References - curated
# Reference Title Reference Citation
1. Strains registered by the National Bio Resource Project for the Rat in Japan Personal Communication with NBRP
2. RGD Strain RSO annotation pipeline RGD Automated Pipelines


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics This strain shows severe combined immunodeficiency_SCID_and growth retardation caused by a 20-bp deletion in the exon 1 of Prkdc gene and a 653-bp deletion in Il2rg gene 1302502
strain_reproduction maintained by mating between Il2rg-homozygous/Prkdc-heterozygous rats 1302502