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Gene: Hps6 (HPS6, biogenesis of lysosomal organelles complex 2 subunit 3) Rattus norvegicus
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Symbol: Hps6
Name: HPS6, biogenesis of lysosomal organelles complex 2 subunit 3
Description: Predicted to have GTP-dependent protein binding activity and Rab GTPase binding activity. Predicted to be involved in several processes, including blood coagulation; lysosome localization; and melanocyte differentiation. Predicted to localize to the BLOC-2 complex and lysosomal membrane. Human ortholog(s) of this gene implicated in Hermansky-Pudlak syndrome and Hermansky-Pudlak syndrome 6. Orthologous to human HPS6 (HPS6 biogenesis of lysosomal organelles complex 2 subunit 3); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,3-dinitrobenzene; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Hermansky-Pudlak syndrome 6; hermansky-Pudlak syndrome 6 protein homolog; Hsp6; MGC93064; ru; ruby-eye protein homolog; ruby-eye-like protein
Orthologs:
Allele / Splice: Hps6m1Mcwi  
Genetic Models: SS-Hps6m1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01265,761,818 - 265,764,427 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01273,191,755 - 273,194,364 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41251,226,344 - 251,228,953 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11251,486,912 - 251,489,521 (+)NCBI
Celera1240,659,828 - 240,662,437 (+)NCBICelera
Cytogenetic Map1q54NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Hps6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 631341
Created: 2003-08-13
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.