Gene: Slc8a2 (solute carrier family 8 member A2) Rattus norvegicus
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Symbol: Slc8a2
Name: solute carrier family 8 member A2
Description: ENCODES a protein that exhibits calcium:cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration; calcium:sodium antiporter activity; INVOLVED IN calcium ion export across plasma membrane; calcium ion import across plasma membrane; calcium ion transport into cytosol; PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH brain ischemia; Reperfusion Injury; status epilepticus; FOUND IN cell projection; dendritic spine; integral component of mitochondrial membrane; INTERACTS WITH 6-propyl-2-thiouracil; ammonium chloride; Brodifacoum
AGR Description: Exhibits calcium:cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration and calcium:sodium antiporter activity; involved in cation transport, response to vitamin D, and telencephalon development; localizes to several cellular components, including the dendritic spine, integral component of postsynaptic membrane, and intracellular organelle; biomarker of brain ischemia and status epilepticus; orthologous to human SLC8A2 (solute carrier family 8 member A2).
Merged Description: Exhibits calcium:cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration and calcium:sodium antiporter activity; involved in cation transport, response to vitamin D, and telencephalon development; localizes to several cellular components, including the dendritic spine, integral component of postsynaptic membrane, and intracellular organelle; biomarker of brain ischemia and status epilepticus; orthologous to human SLC8A2 (solute carrier family 8 member A2); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; INTERACTS WITH 6-propyl-2-thiouracil; ammonium chloride; Brodifacoum.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: na(+)/Ca(2+)-exchange protein 2; Ncx2; sodium/calcium exchanger 2; solute carrier family 8 (sodium/calcium exchanger), member 2; solute carrier family 8 member 2
Orthologs:
Homo sapiens (human) : SLC8A2 (solute carrier family 8 member A2)  HGNC  Alliance
Mus musculus (house mouse) : Slc8a2 (solute carrier family 8 (sodium/calcium exchanger), member 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc8a2 (solute carrier family 8 member A2)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC8A2 (solute carrier family 8 member A2)
Canis lupus familiaris (dog) : SLC8A2 (solute carrier family 8 member A2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc8a2 (solute carrier family 8 member A2)
Sus scrofa (pig) : SLC8A2 (solute carrier family 8 member A2)
more info ...
Allele / Splice: Slc8a2m1Mcwi  
Genetic Models: FHH-Slc8a2m1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0178,029,555 - 78,054,042 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0179,296,259 - 79,320,746 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4176,473,938 - 76,498,624 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1176,552,048 - 76,576,735 (+)NCBI
Celera171,312,731 - 71,337,222 (+)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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Sequence

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Strain Sequence Variants (Rnor 5.0)

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Nomenclature History
RGD Curation Notes
  
More on Slc8a2
Alliance Gene
NCBI Gene
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JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620194
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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