Gene: Robo1 (roundabout guidance receptor 1) Rattus norvegicus
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Symbol: Robo1
Name: roundabout guidance receptor 1
Description: ENCODES a protein that exhibits axon guidance receptor activity; identical protein binding (ortholog); LRR domain binding (ortholog); INVOLVED IN axon guidance; axon midline choice point recognition; central nervous system development; ASSOCIATED WITH Brain Injuries; non-small cell lung carcinoma; adenocarcinoma (ortholog); FOUND IN axon; neuronal cell body; axolemma (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; androgen antagonist; bis(2-ethylhexyl) phthalate
AGR Description: Exhibits axon guidance receptor activity; involved in axon midline choice point recognition, regulation of dendrite morphogenesis, and spinal cord development; localizes to the axon and neuronal cell body; biomarker of non-small cell lung carcinoma; orthologous to human ROBO1 (roundabout guidance receptor 1).
Merged Description: Exhibits axon guidance receptor activity; involved in axon midline choice point recognition, regulation of dendrite morphogenesis, and spinal cord development; localizes to the axon and neuronal cell body; biomarker of non-small cell lung carcinoma; orthologous to human ROBO1 (roundabout guidance receptor 1); INTERACTS WITH 6-propyl-2-thiouracil; androgen antagonist; bis(2-ethylhexyl) phthalate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC683548; roundabout homolog 1; roundabout, axon guidance receptor, homolog 1; similar to roundabout homolog 1
Orthologs:
Homo sapiens (human) : ROBO1 (roundabout guidance receptor 1)  HGNC  Alliance
Mus musculus (house mouse) : Robo1 (roundabout guidance receptor 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Robo1 (roundabout guidance receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ROBO1 (roundabout guidance receptor 1)
Canis lupus familiaris (dog) : ROBO1 (roundabout guidance receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Robo1 (roundabout guidance receptor 1)
Sus scrofa (pig) : ROBO1 (roundabout guidance receptor 1)
more info ...
Allele / Splice: Robo1Tn(sb-T2/Bart3)2.327Mcwi  
Genetic Models: F344-Robo1Tn(sb-T2/Bart3)2.327Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0119,079,291 - 10,146,302 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01113,314,508 - 13,808,775 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41110,784,947 - 11,720,646 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11110,784,946 - 11,720,646 (+)NCBI
Celera1110,598,877 - 11,659,942 (+)NCBICelera
Cytogenetic Map11p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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Genomics

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QTLs in Region (Rnor_6.0)
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Sequence

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Strain Sequence Variants (Rnor 5.0)

Additional Information

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Nomenclature History
RGD Curation Notes
  
More on Robo1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 61941
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.