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Gene: Rag1 (recombination activating 1) Rattus norvegicus
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Symbol: Rag1
Name: recombination activating 1
Description: Predicted to contribute to double-stranded DNA endodeoxyribonuclease activity. Involved in regulation of behavioral fear response and visual learning. Predicted to localize to the DNA recombinase complex; endodeoxyribonuclease complex; and nucleus. Used to study hypertension and severe combined immunodeficiency. Human ortholog(s) of this gene implicated in Omenn syndrome; severe combined immunodeficiency; and severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, Nk cell-positive. Orthologous to human RAG1 (recombination activating 1); PARTICIPATES IN primary immunodeficiency pathway; INTERACTS WITH (RS)-amphetamine; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC295954; recombination activating gene 1; recombination activation protein 1; V(D)J recombination-activating protein 1
Orthologs:
Homo sapiens (human) : RAG1 (recombination activating 1)  HGNC  Alliance
Mus musculus (house mouse) : Rag1 (recombination activating 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rag1 (recombination activating 1)
Pan paniscus (bonobo/pygmy chimpanzee) : RAG1 (recombination activating 1)
Canis lupus familiaris (dog) : RAG1 (recombination activating 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rag1 (recombination activating 1)
Sus scrofa (pig) : RAG1 (recombination activating 1)
more info ...
Allele / Splice: Rag1em1Mcwi   Rag1em2Mcwi   Rag1em1Ztm   Rag1em1Ang   Rag1em1Sage  
Genetic Models: LEW-Rag1em1Ztm SD-Rag1em1Ang SD-Rag1em1Sage F344-Rag1em1Sage SS-Rag1em1Mcwi SS-Rag1em2Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0391,206,394 - 91,217,491 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0397,866,048 - 97,877,145 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4386,780,782 - 86,791,878 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1386,683,155 - 86,683,666 (-)NCBI
Celera387,023,254 - 87,034,352 (-)NCBICelera
Cytogenetic Map3q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Rag1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 619790
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.