Rag1 (recombination activating 1) - Rat Genome Database

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Gene: Rag1 (recombination activating 1) Rattus norvegicus
Analyze
Symbol: Rag1
Name: recombination activating 1
RGD ID: 619790
Description: Predicted to enable several functions, including protein homodimerization activity; ubiquitin protein ligase activity; and zinc ion binding activity. Predicted to contribute to double-stranded DNA endonuclease activity. Involved in regulation of behavioral fear response and visual learning. Predicted to be part of DNA recombinase complex and endodeoxyribonuclease complex. Predicted to be active in nucleus. Used to study hypertension and severe combined immunodeficiency. Human ortholog(s) of this gene implicated in Omenn syndrome; combined cellular and humoral immune defects with granulomas; severe combined immunodeficiency; and severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, Nk cell-positive. Orthologous to human RAG1 (recombination activating 1); PARTICIPATES IN primary immunodeficiency pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride; amphetamine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC295954; recombination activating gene 1; recombination activation protein 1; recombination-activating protein 1; V(D)J recombination-activating protein 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: Rag1em1Mcwi   Rag1em2Mcwi   Rag1em1Ztm   Rag1em1Ang   Rag1em1Sage  
Genetic Models: LEW-Rag1em1Ztm SS-Rag1em1Mcwi SS-Rag1em2Mcwi SD-Rag1em1Ang SD-Rag1em1Sage F344-Rag1em1Sage
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2387,917,061 - 87,928,158 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl387,917,004 - 87,928,291 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx391,407,934 - 91,419,028 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.03100,006,959 - 100,018,053 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0397,839,202 - 97,850,299 (-)NCBIRnor_WKY
Rnor_6.0391,206,394 - 91,217,491 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl391,206,394 - 91,217,491 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0397,866,048 - 97,877,145 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4386,780,782 - 86,791,878 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1386,683,155 - 86,683,666 (-)NCBI
Celera387,023,254 - 87,034,352 (-)NCBICelera
Cytogenetic Map3q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Contribution of Rag1 to spatial memory ability in rats. Fang M, etal., Behav Brain Res. 2013 Jan 1;236(1):200-9. doi: 10.1016/j.bbr.2012.09.002. Epub 2012 Sep 8.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. GENETIC MUTATION OF RECOMBINATION ACTIVATING GENE 1 IN DAHL SALT-SENSITIVE RATS ATTENUATES HYPERTENSION AND RENAL DAMAGE. Mattson DL, etal., Am J Physiol Regul Integr Comp Physiol. 2013 Jan 30.
4. Generation of Rag1-knockout immunodeficient rats and mice using engineered meganucleases. Menoret S, etal., FASEB J. 2012 Nov 12.
5. Generation of immunodeficient rats with Rag1 and Il2rg gene deletions and human tissue grafting models. Ménoret S, etal., Transplantation. 2018 Apr 24. doi: 10.1097/TP.0000000000002251.
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. Evidence for the extrathymic origin of intestinal TCRgammadelta(+) T cells in normal rats and for an impairment of this differentiation pathway in BB rats. Ramanathan S, etal., J Immunol 2002 Mar 1;168(5):2182-7.
10. GOA pipeline RGD automated data pipeline
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Comprehensive gene review and curation RGD comprehensive gene curation
14. RAG mutations in human B cell-negative SCID. Schwarz K, etal., Science. 1996 Oct 4;274(5284):97-9.
15. Partial V(D)J recombination activity leads to Omenn syndrome. Villa A, etal., Cell. 1998 May 29;93(5):885-96.
16. Zinc-finger nuclease mediated disruption of Rag1 in the LEW/Ztm rat. Zschemisch NH, etal., BMC Immunol. 2012 Nov 8;13:60. doi: 10.1186/1471-2172-13-60.
Additional References at PubMed
PMID:1547488   PMID:2360047   PMID:8284210   PMID:9215624   PMID:9228952   PMID:10601033   PMID:11214319   PMID:11976687   PMID:12629039   PMID:14670978   PMID:14671314   PMID:15371245  
PMID:15522792   PMID:15728238   PMID:16929832   PMID:18684012   PMID:19396172   PMID:19448632   PMID:20122409   PMID:21149691   PMID:22801499   PMID:29537860  


Genomics

Comparative Map Data
Rag1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2387,917,061 - 87,928,158 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl387,917,004 - 87,928,291 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx391,407,934 - 91,419,028 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.03100,006,959 - 100,018,053 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0397,839,202 - 97,850,299 (-)NCBIRnor_WKY
Rnor_6.0391,206,394 - 91,217,491 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl391,206,394 - 91,217,491 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0397,866,048 - 97,877,145 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4386,780,782 - 86,791,878 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1386,683,155 - 86,683,666 (-)NCBI
Celera387,023,254 - 87,034,352 (-)NCBICelera
Cytogenetic Map3q31NCBI
RAG1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381136,510,353 - 36,579,762 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1136,510,372 - 36,593,156 (+)EnsemblGRCh38hg38GRCh38
GRCh371136,531,903 - 36,601,312 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361136,546,139 - 36,557,851 (+)NCBINCBI36Build 36hg18NCBI36
Build 341136,546,138 - 36,557,871NCBI
Celera1136,741,994 - 36,753,743 (+)NCBICelera
Cytogenetic Map11p12NCBI
HuRef1136,292,349 - 36,304,098 (+)NCBIHuRef
CHM1_11136,588,249 - 36,599,998 (+)NCBICHM1_1
T2T-CHM13v2.01136,653,524 - 36,722,938 (+)NCBIT2T-CHM13v2.0
Rag1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392101,468,597 - 101,479,877 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2101,468,627 - 101,479,846 (-)EnsemblGRCm39 Ensembl
GRCm382101,638,252 - 101,649,532 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2101,638,282 - 101,649,501 (-)EnsemblGRCm38mm10GRCm38
MGSCv372101,478,409 - 101,489,689 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362101,439,121 - 101,450,340 (-)NCBIMGSCv36mm8
Celera2102,863,243 - 102,874,521 (-)NCBICelera
Cytogenetic Map2E2NCBI
cM Map253.88NCBI
Rag1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554229,891,878 - 9,919,504 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554229,891,878 - 9,928,569 (-)NCBIChiLan1.0ChiLan1.0
RAG1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11136,356,483 - 36,418,891 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1136,412,420 - 36,422,904 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01136,483,697 - 36,546,242 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
RAG1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11831,628,231 - 31,639,980 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1831,630,737 - 31,641,660 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1831,238,815 - 31,241,946 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01832,241,825 - 32,244,956 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1832,241,825 - 32,244,956 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11831,811,828 - 31,814,959 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01831,396,201 - 31,399,332 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01832,033,403 - 32,036,534 (-)NCBIUU_Cfam_GSD_1.0
Rag1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494728,691,865 - 28,695,927 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365331,817,135 - 1,827,393 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049365331,817,135 - 1,827,393 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAG1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl224,561,156 - 24,573,851 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1224,565,447 - 24,573,853 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2226,730,528 - 26,733,659 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RAG1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1128,667,996 - 28,701,002 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666038125,803,873 - 125,811,767 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rag1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476710,694,867 - 10,698,001 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476710,694,867 - 10,698,041 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rag1
50 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1140
Count of miRNA genes:355
Interacting mature miRNAs:503
Transcripts:ENSRNOT00000006115
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3191609953Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)31086191289878372Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
61419Cia11Collagen induced arthritis QTL 115.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)33035677398535386Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)333703347104104347Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
1331777Bw24Body weight QTL 243.503body mass (VT:0001259)body weight (CMO:0000012)33945463789115240Rat
1331795Rf30Renal function QTL 303.708urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)33945463789115240Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)341874578104104347Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
1300178Hrtrt4Heart rate QTL 43.74heart pumping trait (VT:2000009)heart rate (CMO:0000002)34382736490905114Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)343827364121056321Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)350437042119183768Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)350437504115638231Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)353184593115665732Rat
61377Edpm3Estrogen-dependent pituitary mass QTL 37.050.038pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)35318469289878207Rat
731180Bp152Blood pressure QTL 1520.03arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)35378111291609953Rat
731180Bp152Blood pressure QTL 1520.03arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)35378111291609953Rat
731180Bp152Blood pressure QTL 1520.03arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35378111291609953Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)361017749121056321Rat
631200Cm25Cardiac mass QTL 254.80.0001heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)36113434889115068Rat
1582210Bw71Body weight QTL 713.30.0012body mass (VT:0001259)body weight (CMO:0000012)364655305115665732Rat
1582221Kidm30Kidney mass QTL 303.50.0008kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)364655305115665732Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)370348525121056321Rat
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)370653097121056321Rat
1600376Arunc5Aerobic running capacity QTL 50.21exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)373376539118376539Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)378196190146592722Rat
2302273Gluco35Glucose level QTL 355.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)380800231114297550Rat

Markers in Region
GDB:624547  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2387,920,889 - 87,921,462 (+)MAPPERmRatBN7.2
Rnor_6.0391,210,223 - 91,210,795NCBIRnor6.0
Rnor_5.0397,869,877 - 97,870,449UniSTSRnor5.0
RGSC_v3.4386,784,610 - 86,785,182UniSTSRGSC3.4
Celera387,027,084 - 87,027,656UniSTS
Cytogenetic Map3q31UniSTS


Genetic Models
This gene Rag1 is modified in the following models/strains

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 6 6
Medium 2 2
Low 8 21 17 8 17 7 7 2 2 14 7 7
Below cutoff 14 20 16 3 16 1 1 21 22 13 3 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000006115   ⟹   ENSRNOP00000006115
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl387,917,004 - 87,928,291 (-)Ensembl
Rnor_6.0 Ensembl391,206,394 - 91,217,491 (-)Ensembl
RefSeq Acc Id: NM_053468   ⟹   NP_445920
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2387,917,061 - 87,928,158 (-)NCBI
Rnor_6.0391,206,394 - 91,217,491 (-)NCBI
Rnor_5.0397,866,048 - 97,877,145 (-)NCBI
RGSC_v3.4386,780,782 - 86,791,878 (-)RGD
Celera387,023,254 - 87,034,352 (-)RGD
Sequence:
Reference Sequences
RefSeq Acc Id: NP_445920   ⟸   NM_053468
- UniProtKB: G3V6K9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000006115   ⟸   ENSRNOT00000006115
Protein Domains
NBD   RAG1-type   RAG1_imp_bd   RING-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-G3V6K9-F1-model_v2 AlphaFold G3V6K9 1-1040 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692243
Promoter ID:EPDNEW_R2766
Type:multiple initiation site
Name:Rag1_1
Description:recombination activating 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0391,217,521 - 91,217,581EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619790 AgrOrtholog
BioCyc Gene G2FUF-48611 BioCyc
Ensembl Genes ENSRNOG00000004630 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000006115 ENTREZGENE
  ENSRNOP00000006115.3 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000006115 ENTREZGENE
  ENSRNOT00000006115.6 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
InterPro RAG1 UniProtKB/TrEMBL
  RAG1_imp-bd UniProtKB/TrEMBL
  RAG_nonamer-bd_dom UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C3HC4_RING-type UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/TrEMBL
  Znf_VDJ_recomb-activ_1 UniProtKB/TrEMBL
KEGG Report rno:84600 UniProtKB/TrEMBL
NCBI Gene 84600 ENTREZGENE
PANTHER PTHR11539 UniProtKB/TrEMBL
Pfam RAG1 UniProtKB/TrEMBL
  RAG1_imp_bd UniProtKB/TrEMBL
  zf-C3HC4 UniProtKB/TrEMBL
  zf-RAG1 UniProtKB/TrEMBL
PhenoGen Rag1 PhenoGen
PROSITE NBD UniProtKB/TrEMBL
  ZF_RAG1 UniProtKB/TrEMBL
  ZF_RING_1 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
SMART RING UniProtKB/TrEMBL
Superfamily-SCOP SSF57667 UniProtKB/TrEMBL
UniProt A0A858CAG1_RAT UniProtKB/TrEMBL
  G3V6K9 ENTREZGENE, UniProtKB/TrEMBL
  O70607_RAT UniProtKB/TrEMBL
  Q68AY0_RAT UniProtKB/TrEMBL
  Q6WDI9_RAT UniProtKB/TrEMBL
  Q99NN7_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-04-27 Rag1  recombination activating gene 1  Rag1_predicted  recombination activating gene 1 (predicted)  Data Merged 737654 APPROVED
2005-01-20 Rag1  recombination activating gene 1    recombination activation protein 1  Name updated 1299863 APPROVED
2005-01-12 Rag1_predicted  recombination activating gene 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED
2002-08-07 Rag1  recombination activation protein 1      Symbol and Name status set to provisional 70820 PROVISIONAL