Gene: Rag1 (recombination activating 1) Rattus norvegicus
Analyze
Symbol:
Rag1
Name:
recombination activating 1
Description:
Predicted to contribute to double-stranded DNA endodeoxyribonuclease activity. Involved in regulation of behavioral fear response and visual learning. Predicted to localize to the DNA recombinase complex; endodeoxyribonuclease complex; and nucleus. Used to study hypertension and severe combined immunodeficiency. Human ortholog(s) of this gene implicated in Omenn syndrome; severe combined immunodeficiency; and severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, Nk cell-positive. Orthologous to human RAG1 (recombination activating 1); PARTICIPATES IN primary immunodeficiency pathway; INTERACTS WITH ammonium chloride; amphetamine; bisphenol A.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Also known as:
LOC295954; recombination activating gene 1; recombination activation protein 1; V(D)J recombination-activating protein 1
Orthologs:
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
RAG1 (recombination activating 1) HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):
Rag1 (recombination activating 1) HGNC
Treefam, EggNOG, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, Panther, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):
Rag1 (recombination activating 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
RAG1 (recombination activating 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
RAG1 (recombination activating 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Rag1 (recombination activating 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
RAG1 (recombination activating 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):
RAG1 (recombination activating 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Rag1 (recombination activating 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Homo sapiens (human):
RAG1 (recombination activating 1)
Alliance
DIOPT (Ensembl Compara, HGNC, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, TreeFam)
Mus musculus (house mouse):
Rag1 (recombination activating 1)
Alliance
DIOPT (Ensembl Compara, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, TreeFam)
Danio rerio (zebrafish):
rag1 (recombination activating gene 1)
Alliance
DIOPT (Ensembl Compara, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, TreeFam)
Allele / Splice:
Rag1em1Mcwi
Rag1em2Mcwi
Rag1em1Ztm
Rag1em1Ang
Rag1em1Sage
Genetic Models:
LEW-Rag1em1Ztm
SD-Rag1em1Ang
SD-Rag1em1Sage
F344-Rag1em1Sage
SS-Rag1em1Mcwi
SS-Rag1em2Mcwi
Latest Assembly:
Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Rnor_6.0 3 91,206,394 - 91,217,491 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 3 91,206,394 - 91,217,491 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 3 97,866,048 - 97,877,145 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 3 86,780,782 - 86,791,878 (-) NCBI RGSC3.4 rn4 RGSC3.4 RGSC_v3.1 3 86,683,155 - 86,683,666 (-) NCBI Celera 3 87,023,254 - 87,034,352 (-) NCBI Celera Cytogenetic Map 3 q31 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Disease Annotations
Imported Annotations - ClinVar
Alpha/Beta T-Cell Lymphopenia with Gamma/Delta T-Cell Expansion, Severe Cytomegalovirus Infection, and Autoimmunity ISO RGD:1317876 8554872 ClinVar Annotator: match by null ClinVar PMID:11313270 , PMID:16276422 Alpha/Beta T-Cell Lymphopenia with Gamma/Delta T-Cell Expansion, Severe Cytomegalovirus Infection, and Autoimmunity ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Alpha/beta T-cell lymphopenia with gamma/delta T-cell expansion, severe cytomegalovirus infection, and autoimmunity ClinVar PMID:25741868 Alpha/Beta T-Cell Lymphopenia with Gamma/Delta T-Cell Expansion, Severe Cytomegalovirus Infection, and Autoimmunity ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Alpha/beta T-cell lymphopenia with gamma/delta T-cell expansion, severe cytomegalovirus infection, and autoimmunity ClinVar PMID:11133745 more ... Alpha/Beta T-Cell Lymphopenia with Gamma/Delta T-Cell Expansion, Severe Cytomegalovirus Infection, and Autoimmunity ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Alpha/beta T-cell lymphopenia with gamma/delta T-cell expansion, severe cytomegalovirus infection, and autoimmunity ClinVar PMID:25741868 , PMID:28492532 Alpha/Beta T-Cell Lymphopenia with Gamma/Delta T-Cell Expansion, Severe Cytomegalovirus Infection, and Autoimmunity ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Alpha/beta T-cell lymphopenia with gamma/delta T-cell expansion, severe cytomegalovirus infection, and autoimmunity ClinVar PMID:11133745 , PMID:25741868 Alpha/Beta T-Cell Lymphopenia with Gamma/Delta T-Cell Expansion, Severe Cytomegalovirus Infection, and Autoimmunity ISO RGD:1317876 8554872 ClinVar Annotator: match by null ClinVar PMID:11121059 more ... Alpha/Beta T-Cell Lymphopenia with Gamma/Delta T-Cell Expansion, Severe Cytomegalovirus Infection, and Autoimmunity ISO RGD:1317876 8554872 ClinVar Annotator: match by OMIM:609889 ClinVar PMID:16276422 Alpha/Beta T-Cell Lymphopenia with Gamma/Delta T-Cell Expansion, Severe Cytomegalovirus Infection, and Autoimmunity ISO RGD:1317876 8554872 ClinVar Annotator: match by OMIM:609889 ClinVar PMID:11133745 , PMID:16276422 Combined Cellular and Humoral Immune Defects with Granulomas ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Combined cellular and humoral immune defects with granulomas ClinVar PMID:25741868 , PMID:28492532 Combined Cellular and Humoral Immune Defects with Granulomas ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Combined cellular and humoral immune defects with granulomas ClinVar PMID:26457731 more ... Combined Cellular and Humoral Immune Defects with Granulomas ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Combined cellular and humoral immune defects with granulomas ClinVar PMID:16960852 more ... Combined Cellular and Humoral Immune Defects with Granulomas ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Combined cellular and humoral immune defects with granulomas ClinVar PMID:21664875 more ... Combined Cellular and Humoral Immune Defects with Granulomas ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Combined cellular and humoral immune defects with granulomas ClinVar PMID:24290284 , PMID:28492532 Combined Cellular and Humoral Immune Defects with Granulomas ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Combined cellular and humoral immune defects with granulomas ClinVar PMID:11133745 more ... Combined Cellular and Humoral Immune Defects with Granulomas ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Combined cellular and humoral immune defects with granulomas ClinVar PMID:18463379 , PMID:28492532 Combined Cellular and Humoral Immune Defects with Granulomas ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Combined cellular and humoral immune defects with granulomas ClinVar PMID:17572155 more ... Combined Cellular and Humoral Immune Defects with Granulomas ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Combined cellular and humoral immune defects with granulomas ClinVar PMID:11133745 more ... Combined Cellular and Humoral Immune Defects with Granulomas ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Combined cellular and humoral immune defects with granulomas ClinVar PMID:21624848 more ... Combined Cellular and Humoral Immune Defects with Granulomas ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Combined cellular and humoral immune defects with granulomas ClinVar PMID:11133745 more ... Combined Cellular and Humoral Immune Defects with Granulomas ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Combined cellular and humoral immune defects with granulomas ClinVar PMID:11313270 , PMID:28492532 Combined Cellular and Humoral Immune Defects with Granulomas ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Combined cellular and humoral immune defects with granulomas ClinVar PMID:25741868 Combined Cellular and Humoral Immune Defects with Granulomas ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Combined cellular and humoral immune defects with granulomas ClinVar PMID:11133745 more ... Combined Cellular and Humoral Immune Defects with Granulomas ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Combined cellular and humoral immune defects with granulomas ClinVar Combined Cellular and Humoral Immune Defects with Granulomas ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Combined cellular and humoral immune defects with granulomas ClinVar PMID:11133745 more ... Combined Cellular and Humoral Immune Defects with Granulomas ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Combined cellular and humoral immune defects with granulomas ClinVar PMID:17075247 more ... Combined Cellular and Humoral Immune Defects with Granulomas ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Combined cellular and humoral immune defects with granulomas ClinVar PMID:10701853 more ... Combined Cellular and Humoral Immune Defects with Granulomas ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Combined cellular and humoral immune defects with granulomas ClinVar PMID:18442948 , PMID:28492532 Combined Cellular and Humoral Immune Defects with Granulomas ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Combined cellular and humoral immune defects with granulomas ClinVar PMID:11313270 more ... Combined Cellular and Humoral Immune Defects with Granulomas ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Combined cellular and humoral immune defects with granulomas ClinVar PMID:24290284 more ... Combined Cellular and Humoral Immune Defects with Granulomas ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Combined cellular and humoral immune defects with granulomas ClinVar PMID:28492532 Combined Cellular and Humoral Immune Defects with Granulomas ISO RGD:1317876 8554872 ClinVar Annotator: match by OMIM:233650 ClinVar PMID:20489056 Combined Cellular and Humoral Immune Defects with Granulomas ISO RGD:1317876 8554872 ClinVar Annotator: match by OMIM:233650 ClinVar PMID:18463379 Histiocytic Sarcoma ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Histiocytic medullary reticulosis ClinVar Histiocytic Sarcoma ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Histiocytic medullary reticulosis ClinVar PMID:11133745 more ... Histiocytic Sarcoma ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Histiocytic medullary reticulosis ClinVar PMID:17075247 more ... Histiocytic Sarcoma ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Histiocytic medullary reticulosis ClinVar PMID:10701853 more ... Histiocytic Sarcoma ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Histiocytic medullary reticulosis ClinVar PMID:11121059 more ... Histiocytic Sarcoma ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Histiocytic medullary reticulosis ClinVar PMID:11313270 , PMID:16276422 Histiocytic Sarcoma ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Histiocytic medullary reticulosis ClinVar PMID:10606976 more ... Histiocytic Sarcoma ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Histiocytic medullary reticulosis ClinVar PMID:11121059 Histiocytic Sarcoma ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Histiocytic medullary reticulosis ClinVar PMID:24033266 , PMID:25741868 Histiocytic Sarcoma ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Histiocytic medullary reticulosis ClinVar PMID:11313270 more ... Histiocytic Sarcoma ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Histiocytic medullary reticulosis ClinVar PMID:25741868 Histiocytic Sarcoma ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Histiocytic medullary reticulosis ClinVar PMID:15908971 Histiocytic Sarcoma ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Histiocytic medullary reticulosis ClinVar PMID:9630231 Histiocytic Sarcoma ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Histiocytic medullary reticulosis ClinVar PMID:28492532 Histiocytic Sarcoma ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Histiocytic medullary reticulosis ClinVar PMID:25741868 , PMID:28492532 severe combined immunodeficiency ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Severe combined immunodeficiency disease ClinVar PMID:21664875 more ... severe combined immunodeficiency ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Severe combined immunodeficiency disease ClinVar PMID:24290284 , PMID:28492532 severe combined immunodeficiency ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Severe combined immunodeficiency ClinVar PMID:11133745 more ... severe combined immunodeficiency ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Severe Combined Immune Deficiency ClinVar PMID:24033266 , PMID:25741868 severe combined immunodeficiency ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Severe Combined Immune Deficiency ClinVar PMID:28492532 severe combined immunodeficiency ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Severe Combined Immunodeficiency ClinVar severe combined immunodeficiency ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Severe Combined Immunodeficiency ClinVar PMID:25741868 severe combined immunodeficiency ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Severe Combined Immune Deficiency ClinVar PMID:25741868 , PMID:28492532 severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, NK cell-positive ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Severe combined immunodeficiency, b cell-negative ClinVar PMID:17572155 more ... severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, NK cell-positive ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Severe immunodeficiency, autosomal recessive, T-cell negative, B-cell negative, NK cell-positive ClinVar PMID:21664875 more ... severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, NK cell-positive ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Severe immunodeficiency, autosomal recessive, T-cell negative, B-cell negative, NK cell-positive ClinVar PMID:23122631 more ... severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, NK cell-positive ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Severe immunodeficiency, autosomal recessive, T-cell negative, B-cell negative, NK cell-positive ClinVar PMID:20956421 more ... severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, NK cell-positive ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Severe immunodeficiency, autosomal recessive, T-cell negative, B-cell negative, NK cell-positive ClinVar PMID:11313270 more ... severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, NK cell-positive ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Severe immunodeficiency, autosomal recessive, T-cell negative, B-cell negative, NK cell-positive ClinVar severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, NK cell-positive ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Severe combined immunodeficiency, b cell-negative ClinVar PMID:11313270 , PMID:16276422 severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, NK cell-positive ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Severe immunodeficiency, autosomal recessive, T-cell negative, B-cell negative, NK cell-positive ClinVar PMID:11133745 , PMID:28492532 severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, NK cell-positive ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Severe immunodeficiency, autosomal recessive, T-cell negative, B-cell negative, NK cell-positive ClinVar PMID:11313270 more ... severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, NK cell-positive ISO RGD:1317876 8554872 ClinVar Annotator: match by term: Severe combined immunodeficiency, b cell-negative ClinVar PMID:8810255
Gene-Chemical Interaction Annotations
