Oprl1 (opioid related nociceptin receptor 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Oprl1 (opioid related nociceptin receptor 1) Rattus norvegicus
Analyze
Symbol: Oprl1
Name: opioid related nociceptin receptor 1
RGD ID: 68438
Description: Enables protein C-terminus binding activity. Involved in several processes, including conditioned place preference; estrous cycle; and negative regulation of signal transduction. Located in membrane. Used to study alcohol use disorder. Biomarker of sciatic neuropathy. Orthologous to human OPRL1 (opioid related nociceptin receptor 1); INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: kappa-type 3 opioid receptor; KOR-3; KOR3; LC132; MOR-C; nociceptin receptor; nociceptin receptor ORL1; OFQR; opiate receptor-like 1; opioid receptor-like; opioid receptor-like 1; Oprl; ORL1; orphanin FQ receptor; orphanin FQ receptor-a; orphanin FQ receptor-b; orphanin FQ receptor-e; peptide receptor; ROR-C; seven transmembrane G protein-coupled receptor; XOR1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: Oprl1m1Hubr  
Genetic Models: WI-Oprl1m1Hubr-/- WI-Oprl1m1Hubr+/-
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23168,831,934 - 168,839,920 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl3168,834,003 - 168,839,920 (+)Ensembl
Rnor_6.03177,223,779 - 177,231,663 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3177,225,737 - 177,231,663 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03180,932,344 - 180,943,574 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43170,869,862 - 170,873,417 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13170,775,328 - 170,780,949 (+)NCBI
Celera3163,747,719 - 163,753,636 (-)NCBICelera
Cytogenetic Map3q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
1. Briscini L, etal., Eur J Pharmacol. 2002 Jun 28;447(1):59-65.
2. Bunzow JR, etal., FEBS Lett 1994 Jun 27;347(2-3):284-8.
3. Chen Y, etal., FEBS Lett 1994 Jun 27;347(2-3):279-83.
4. Ciccocioppo R, etal., Peptides. 2002 Jan;23(1):117-25.
5. Ciccocioppo R, etal., Psychopharmacology (Berl). 2002 May;161(2):113-9. Epub 2002 Mar 22.
6. Claiborne J, etal., J Neurosci. 2006 Dec 13;26(50):13048-53.
7. Curro D, etal., Gene 2001 Mar 21;266(1-2):139-45.
8. Flores CA, etal., Neuroscience. 2003;118(3):769-78.
9. Fukuda K, etal., FEBS Lett 1994 Apr 18;343(1):42-6.
10. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
11. GOA data from the GO Consortium
12. Hadrup N, etal., Am J Physiol Renal Physiol. 2004 Jul;287(1):F160-8. Epub 2004 Mar 9.
13. Ishihara S, etal., Eur J Pharmacol. 2002 Apr 19;441(1-2):105-14.
14. Klukovits A, etal., Biol Reprod. 2010 Jul;83(1):36-41. doi: 10.1095/biolreprod.109.082222. Epub 2010 Mar 17.
15. Lachowicz JE, etal., J Neurochem 1995 Jan;64(1):34-40.
16. Leventhal L, etal., Eur J Pharmacol. 1998 May 15;349(1):R1-3.
17. Leventhal L, etal., J Pharmacol Exp Ther. 1998 Nov;287(2):538-44.
18. Ma F, etal., Brain Res. 2005 May 10;1043(1-2):214-7.
19. Malinowska B, etal., Naunyn Schmiedebergs Arch Pharmacol. 2000 Jan;361(1):80-4.
20. MGD data from the GO Consortium
21. Micheli L, etal., Eur J Pharmacol. 2015 May 5;754:73-81. doi: 10.1016/j.ejphar.2015.02.020. Epub 2015 Feb 19.
22. NCBI rat LocusLink and RefSeq merged data July 26, 2002
23. RGD automated data pipeline
24. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
25. RGD automated import pipeline for gene-chemical interactions
26. Rizzi A, etal., Neuropharmacology. 2011 Mar;60(4):572-9. doi: 10.1016/j.neuropharm.2010.12.010. Epub 2010 Dec 22.
27. Ruggeri B, etal., J Child Psychol Psychiatry. 2018 Jun;59(6):650-658. doi: 10.1111/jcpp.12843. Epub 2017 Dec 2.
28. Ruiz-Velasco V, etal., J Pharmacol Exp Ther. 2005 Sep;314(3):987-94. Epub 2005 Jun 3.
29. Rutten K, etal., Drug Alcohol Depend. 2011 Apr 1;114(2-3):253-6. doi: 10.1016/j.drugalcdep.2010.10.004. Epub 2010 Nov 20.
30. Silva RM, etal., J Pharmacol Exp Ther. 2002 May;301(2):513-8.
31. Sugino T, etal., Neuroscience. 2006;137(2):537-44. Epub 2005 Nov 28.
32. Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
33. Wang HL, etal., Cell Signal. 2006 May;18(5):670-8. Epub 2005 Jul 14.
34. Wang HL, etal., J Neurochem. 2005 Mar;92(6):1285-94.
35. Wang JB, etal., FEBS Lett 1994 Jul 4;348(1):75-9.
36. Wick MJ, etal., Brain Res Mol Brain Res 1994 Nov;27(1):37-44.
37. Yamamoto T, etal., J Pharmacol Exp Ther. 2006 Jul;318(1):206-13. Epub 2006 Mar 24.
38. Zhao H, etal., Acta Pharmacol Sin. 2002 Apr;23(4):343-8.
Additional References at PubMed
PMID:8137918   PMID:9915326   PMID:10571060   PMID:10814826   PMID:11726686   PMID:11973003   PMID:12217419   PMID:12568343   PMID:12842128   PMID:12842289   PMID:14660000   PMID:15282268  
PMID:15890775   PMID:15948180   PMID:16483692   PMID:17493706   PMID:17499882   PMID:17512052   PMID:17681177   PMID:17766480   PMID:18987291   PMID:19527777   PMID:19720395   PMID:19765615  
PMID:19887453   PMID:20159949   PMID:21925513   PMID:22074385   PMID:22075222   PMID:22120202   PMID:22371475   PMID:23219985   PMID:23337899   PMID:23669068   PMID:23869704   PMID:24452062  
PMID:24978951   PMID:25013167   PMID:25161013   PMID:25875798   PMID:26387568   PMID:26935148   PMID:27127846   PMID:27238748   PMID:27562376   PMID:28280884   PMID:28906039  


Genomics

Candidate Gene Status
Oprl1 is a candidate Gene for QTL Bp286
Comparative Map Data
Oprl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23168,831,934 - 168,839,920 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl3168,834,003 - 168,839,920 (+)Ensembl
Rnor_6.03177,223,779 - 177,231,663 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3177,225,737 - 177,231,663 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03180,932,344 - 180,943,574 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43170,869,862 - 170,873,417 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13170,775,328 - 170,780,949 (+)NCBI
Celera3163,747,719 - 163,753,636 (-)NCBICelera
Cytogenetic Map3q43NCBI
OPRL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2064,080,082 - 64,100,643 (+)EnsemblGRCh38hg38GRCh38
GRCh382064,080,082 - 64,100,643 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372062,711,435 - 62,731,996 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362062,181,932 - 62,202,440 (+)NCBINCBI36hg18NCBI36
Build 342062,181,931 - 62,202,440NCBI
Celera2059,397,677 - 59,420,493 (+)NCBI
Cytogenetic Map20q13.33NCBI
HuRef2059,457,992 - 59,460,858 (+)NCBIHuRef
CHM1_12062,612,487 - 62,633,363 (+)NCBICHM1_1
Oprl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392181,356,585 - 181,362,778 (+)NCBIGRCm39mm39
GRCm39 Ensembl2181,356,809 - 181,362,778 (+)Ensembl
GRCm382181,715,000 - 181,720,985 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2181,715,016 - 181,720,985 (+)EnsemblGRCm38mm10GRCm38
MGSCv372181,449,749 - 181,455,677 (+)NCBIGRCm37mm9NCBIm37
MGSCv362181,644,450 - 181,650,378 (+)NCBImm8
Celera2185,797,636 - 185,803,570 (+)NCBICelera
Cytogenetic Map2H4NCBI
cM Map2103.74NCBI
Oprl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955528161,673 - 167,937 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955528161,673 - 184,515 (-)NCBIChiLan1.0ChiLan1.0
OPRL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12062,004,176 - 62,017,866 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2062,004,176 - 62,017,866 (+)Ensemblpanpan1.1panPan2
OPRL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12447,530,039 - 47,537,477 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2447,508,136 - 47,537,250 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2446,652,476 - 46,671,129 (+)NCBI
ROS_Cfam_1.02448,657,531 - 48,675,053 (+)NCBI
UMICH_Zoey_3.12447,502,159 - 47,521,409 (+)NCBI
UNSW_CanFamBas_1.02447,626,586 - 47,644,098 (+)NCBI
UU_Cfam_GSD_1.02448,365,597 - 48,383,399 (+)NCBI
Oprl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640195,806,255 - 195,819,941 (+)NCBI
SpeTri2.0NW_00493651411,264,392 - 11,273,584 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OPRL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1762,897,727 - 62,913,754 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11762,905,700 - 62,913,018 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Oprl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474129,713,937 - 29,720,617 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
D3Hmgc22  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23168,832,336 - 168,832,503 (+)MAPPERmRatBN7.2
Rnor_6.03177,224,083 - 177,224,247NCBIRnor6.0
Rnor_5.03180,932,614 - 180,932,778UniSTSRnor5.0
RGSC_v3.43170,867,500 - 170,867,664UniSTSRGSC3.4
Celera3163,755,135 - 163,755,299UniSTS
Cytogenetic Map3q43UniSTS
Oprl  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23168,838,089 - 168,838,321 (+)MAPPERmRatBN7.2
Rnor_6.03177,229,833 - 177,230,064NCBIRnor6.0
Rnor_5.03180,938,364 - 180,938,595UniSTSRnor5.0
RGSC_v3.43170,873,250 - 170,873,481UniSTSRGSC3.4
Celera3163,749,318 - 163,749,549UniSTS
Cytogenetic Map3q43UniSTS
RH139571  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23168,839,660 - 168,839,854 (+)MAPPERmRatBN7.2
Rnor_6.03177,231,404 - 177,231,597NCBIRnor6.0
Rnor_5.03180,939,935 - 180,940,128UniSTSRnor5.0
RGSC_v3.43170,874,821 - 170,875,014UniSTSRGSC3.4
Celera3163,747,785 - 163,747,978UniSTS
RH 3.4 Map31553.9UniSTS
Cytogenetic Map3q43UniSTS
RH140403  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23168,839,556 - 168,839,689 (+)MAPPERmRatBN7.2
Rnor_6.03177,231,300 - 177,231,432NCBIRnor6.0
Rnor_5.03180,939,831 - 180,939,963UniSTSRnor5.0
RGSC_v3.43170,874,717 - 170,874,849UniSTSRGSC3.4
Celera3163,747,950 - 163,748,082UniSTS
Cytogenetic Map3q43UniSTS
Oprl1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23168,837,767 - 168,838,013 (+)MAPPERmRatBN7.2
Rnor_6.03177,229,511 - 177,229,756NCBIRnor6.0
Rnor_5.03180,938,042 - 180,938,287UniSTSRnor5.0
RGSC_v3.43170,872,928 - 170,873,173UniSTSRGSC3.4
Celera3163,749,626 - 163,749,871UniSTS
Cytogenetic Map3q43UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3124122556169034231Rat
1578656Vnigr2Vascular neointimal growth QTL 24.2artery morphology trait (VT:0002191)lesioned artery residual lumen area (CMO:0001417)3130656562169034231Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3130656562169034231Rat
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3131635904169034231Rat
2298477Eau4Experimental allergic uveoretinitis QTL 40.0011uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)3137398739169034231Rat
8552952Pigfal13Plasma insulin-like growth factor 1 level QTL 13blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)3138799500169034231Rat
1298068Bp167Blood pressure QTL 1670.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3141074471169034231Rat
2317883Alcrsp26Alcohol response QTL 261.80.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)3145526770169034231Rat
8552791Vie2Viral induced encephalitis QTL 24.1brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)3145956084169034231Rat
1300161Rf10Renal function QTL 103.57renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)3161192952169034231Rat


Genetic Models
This gene Oprl1 is modified in the following models/strains
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1128
Count of miRNA genes:327
Interacting mature miRNAs:438
Transcripts:ENSRNOT00000022509, ENSRNOT00000031328, ENSRNOT00000045845
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 62
Low 14 8 4 4 12 12
Below cutoff 3 10 13 8 4 8 1 1 6 21 3 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001318947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001318948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_031569 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006235736 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006235738 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006235739 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008762474 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591512 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591513 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591514 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591515 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591516 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591517 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104431 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104432 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104433 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF115267 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF178674 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF216218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY152731 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D16438 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L28144 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L29419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L33916 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U01913 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U05239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U07871 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000031328   ⟹   ENSRNOP00000030087
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3168,834,003 - 168,839,920 (+)Ensembl
Rnor_6.0 Ensembl3177,226,417 - 177,230,117 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000045845   ⟹   ENSRNOP00000047053
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3168,834,003 - 168,839,920 (+)Ensembl
Rnor_6.0 Ensembl3177,225,737 - 177,231,663 (+)Ensembl
RefSeq Acc Id: NM_001318947   ⟹   NP_001305876
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23168,834,003 - 168,839,920 (+)NCBI
Rnor_6.03177,225,746 - 177,231,663 (+)NCBI
Celera3163,747,719 - 163,753,636 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001318948   ⟹   NP_001305877
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23168,834,003 - 168,839,920 (+)NCBI
Rnor_6.03177,225,746 - 177,231,663 (+)NCBI
Celera3163,747,719 - 163,753,636 (-)NCBI
Sequence:
RefSeq Acc Id: NM_031569   ⟹   NP_113757
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23168,834,003 - 168,839,920 (+)NCBI
Rnor_6.03177,225,746 - 177,231,663 (+)NCBI
Rnor_5.03180,932,344 - 180,943,574 (+)NCBI
RGSC_v3.43170,869,862 - 170,873,417 (+)RGD
Celera3163,747,719 - 163,753,636 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006235738   ⟹   XP_006235800
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23168,832,486 - 168,839,908 (+)NCBI
Rnor_6.03177,224,550 - 177,231,663 (+)NCBI
Rnor_5.03180,932,344 - 180,943,574 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006235739   ⟹   XP_006235801
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23168,832,483 - 168,839,908 (+)NCBI
Rnor_6.03177,224,550 - 177,231,663 (+)NCBI
Rnor_5.03180,932,344 - 180,943,574 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017591516   ⟹   XP_017447005
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23168,834,796 - 168,839,908 (+)NCBI
Rnor_6.03177,226,580 - 177,231,663 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039104431   ⟹   XP_038960359
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23168,831,934 - 168,839,908 (+)NCBI
RefSeq Acc Id: XM_039104432   ⟹   XP_038960360
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23168,832,482 - 168,839,908 (+)NCBI
RefSeq Acc Id: XM_039104433   ⟹   XP_038960361
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23168,832,489 - 168,839,908 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001305876 (Get FASTA)   NCBI Sequence Viewer  
  NP_001305877 (Get FASTA)   NCBI Sequence Viewer  
  NP_113757 (Get FASTA)   NCBI Sequence Viewer  
  XP_006235800 (Get FASTA)   NCBI Sequence Viewer  
  XP_006235801 (Get FASTA)   NCBI Sequence Viewer  
  XP_017447005 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960359 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960360 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960361 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA16201 (Get FASTA)   NCBI Sequence Viewer  
  AAA21025 (Get FASTA)   NCBI Sequence Viewer  
  AAA50827 (Get FASTA)   NCBI Sequence Viewer  
  AAA69927 (Get FASTA)   NCBI Sequence Viewer  
  AAC37661 (Get FASTA)   NCBI Sequence Viewer  
  AAC42041 (Get FASTA)   NCBI Sequence Viewer  
  AAF70553 (Get FASTA)   NCBI Sequence Viewer  
  AAF70554 (Get FASTA)   NCBI Sequence Viewer  
  AAF80988 (Get FASTA)   NCBI Sequence Viewer  
  AAF80989 (Get FASTA)   NCBI Sequence Viewer  
  AAF80990 (Get FASTA)   NCBI Sequence Viewer  
  AAF80991 (Get FASTA)   NCBI Sequence Viewer  
  AAF80992 (Get FASTA)   NCBI Sequence Viewer  
  AAN77720 (Get FASTA)   NCBI Sequence Viewer  
  AAO13225 (Get FASTA)   NCBI Sequence Viewer  
  BAA03908 (Get FASTA)   NCBI Sequence Viewer  
  EDL88670 (Get FASTA)   NCBI Sequence Viewer  
  EDL88671 (Get FASTA)   NCBI Sequence Viewer  
  EDL88672 (Get FASTA)   NCBI Sequence Viewer  
  EDL88673 (Get FASTA)   NCBI Sequence Viewer  
  EDL88674 (Get FASTA)   NCBI Sequence Viewer  
  EDL88675 (Get FASTA)   NCBI Sequence Viewer  
  EDL88676 (Get FASTA)   NCBI Sequence Viewer  
  EDL88677 (Get FASTA)   NCBI Sequence Viewer  
  EDL88678 (Get FASTA)   NCBI Sequence Viewer  
  EDL88679 (Get FASTA)   NCBI Sequence Viewer  
  EDL88680 (Get FASTA)   NCBI Sequence Viewer  
  P35370 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_113757   ⟸   NM_031569
- Peptide Label: isoform 1
- UniProtKB: P35370 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006235801   ⟸   XM_006235739
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006235800   ⟸   XM_006235738
- Peptide Label: isoform X1
- UniProtKB: P35370 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001305876   ⟸   NM_001318947
- Peptide Label: isoform 1x
- Sequence:
RefSeq Acc Id: NP_001305877   ⟸   NM_001318948
- Peptide Label: isoform 2
- Sequence:
RefSeq Acc Id: XP_017447005   ⟸   XM_017591516
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSRNOP00000030087   ⟸   ENSRNOT00000031328
RefSeq Acc Id: ENSRNOP00000047053   ⟸   ENSRNOT00000045845
RefSeq Acc Id: XP_038960359   ⟸   XM_039104431
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038960360   ⟸   XM_039104432
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038960361   ⟸   XM_039104433
- Peptide Label: isoform X3
Protein Domains
G_PROTEIN_RECEP_F1_2

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BUF/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
DA/OlaHsd (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
F344/Stm (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FXLE16/Stm (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/FarMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MWF/Hsd (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SBH/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/OlalpcvMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/RijCrl (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:68438 AgrOrtholog
Ensembl Genes ENSRNOG00000016768 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000030087 UniProtKB/TrEMBL
  ENSRNOP00000047053 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000031328 UniProtKB/TrEMBL
  ENSRNOT00000045845 UniProtKB/Swiss-Prot
InterPro GPCR_Rhodpsn UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Opioid_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  X_opioid_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:29256 UniProtKB/Swiss-Prot
NCBI Gene 29256 ENTREZGENE
Pfam 7tm_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Oprl1 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  OPIOIDR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  XOPIOIDR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART 7TM_GPCR_Srsx UniProtKB/Swiss-Prot
TIGR TC229480
UniProt OPRX_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q8CH83_RAT UniProtKB/TrEMBL
UniProt Secondary Q791R4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-04-14 Oprl1  opioid related nociceptin receptor 1  Oprl1  opiate receptor-like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-25 Oprl1  opiate receptor-like 1  Oprl1  opioid receptor-like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Oprl1  opioid receptor-like 1  Oprl  opioid receptor-like  Symbol and Name updated 1299863 APPROVED
2002-06-10 Oprl  opioid receptor-like      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in cortex, thalamus, subfornical organ, habenula, hypothalamus, central gray, dorsal raphe, locus coeruleus and the dorsal horn of the spinal cord 1299158
gene_function G protein-linked receptor with homology to opioid receptors 68282
gene_function G protein-linked receptor with homology to opioid receptors 68705
gene_process inhibits adenylate cyclase 68282
gene_process inhibits adenylate cyclase 68705
gene_process activates inwardly rectifying K+ channels 68282
gene_process activates inwardly rectifying K+ channels 68705
gene_process inhibits N-type voltage-operated Ca 2+ channels 68282
gene_process inhibits N-type voltage-operated Ca 2+ channels 68705
gene_process may represent a novel neuropeptide 68282
gene_process may represent a novel neuropeptide 68705