Gene: Oprl1 (opioid related nociceptin receptor 1) Rattus norvegicus
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Symbol: Oprl1
Name: opioid related nociceptin receptor 1
Description: Exhibits protein C-terminus binding activity; involved in several processes, including eating behavior, estrous cycle, and negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway; localizes to the membrane; used to study alcohol use disorder; biomarker of sciatic neuropathy; orthologous to human OPRL1 (opioid related nociceptin receptor 1); INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,4,6-trinitrobenzenesulfonic acid.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: kappa-type 3 opioid receptor; KOR-3; KOR3; LC132; MOR-C; nociceptin receptor; nociceptin receptor ORL1; OFQR; opiate receptor-like 1; opioid receptor-like; opioid receptor-like 1; Oprl; ORL1; orphanin FQ receptor; orphanin FQ receptor-a; orphanin FQ receptor-b; orphanin FQ receptor-e; peptide receptor; ROR-C; seven transmembrane G protein-coupled receptor; XOR1
Orthologs:
Homo sapiens (human) : OPRL1 (opioid related nociceptin receptor 1)  HGNC  Alliance
Mus musculus (house mouse) : Oprl1 (opioid receptor-like 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Oprl1 (opioid related nociceptin receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : OPRL1 (opioid related nociceptin receptor 1)
Canis lupus familiaris (dog) : OPRL1 (opioid related nociceptin receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Oprl1 (opioid related nociceptin receptor 1)
Sus scrofa (pig) : OPRL1 (opioid related nociceptin receptor 1)
more info ...
Allele / Splice: Oprl1m1Hubr  
Genetic Models: WI-Oprl1m1Hubr-/- WI-Oprl1m1Hubr+/-
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03177,223,779 - 177,231,663 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03180,932,344 - 180,943,574 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43170,869,862 - 170,873,417 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13170,775,328 - 170,780,949 (+)NCBI
Celera3163,747,719 - 163,753,636 (-)NCBICelera
Cytogenetic Map3q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Oprl1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68438
Created: 2001-07-11
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.