Gene: Cd59 (CD59 molecule) Rattus norvegicus
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Symbol: Cd59
Name: CD59 molecule
Description: ENCODES a protein that exhibits complement binding; INVOLVED IN negative regulation of activation of membrane attack complex; negative regulation of apoptotic process; negative regulation of complement-dependent cytotoxicity; PARTICIPATES IN coagulation cascade pathway; complement system pathway; ASSOCIATED WITH decreased erythrocyte cell number; increased red blood cell distribution width; increased susceptibility to type III hypersensitivity reaction; ASSOCIATED WITH Acute Necrotizing Pancreatitis; Alcoholic Liver Diseases; anterior uveitis; FOUND IN compact myelin; extracellular space; plasma membrane; INTERACTS WITH 1,3-Propane sultone; 17alpha-ethynylestradiol; 2-HYDROXY-(5-([4-(2-PYRIDINYLAMINO)SULFONYL]PHENYL)AZO)BENZOIC ACID
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Cb59b molecule; CD59 antigen; CD59 glycoprotein; CD59 molecule, complement regulatory protein; Cd59a; Cd59b; CD59b moleucle, complement regulatory protein; MAC-inhibitory protein; MAC-IP; MACIF; MACIP; membrane attack complex inhibition factor; protectin
Orthologs:
Homo sapiens (human) : CD59 (CD59 molecule (CD59 blood group))  HGNC  Alliance
Mus musculus (house mouse) : Cd59b (CD59b antigen)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cd59 (CD59 molecule (CD59 blood group))
Pan paniscus (bonobo/pygmy chimpanzee) : CD59 (CD59 molecule (CD59 blood group))
Canis lupus familiaris (dog) : CD59 (CD59 molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cd59 (CD59 molecule (CD59 blood group))
more info ...
Allele / Splice: Cd59em1Ask  
Genetic Models: SD-Cd59em1Ask-/-
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0394,010,481 - 94,028,660 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03100,650,411 - 100,668,036 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4389,243,600 - 89,245,129 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1389,318,629 - 89,333,534 (-)NCBI
Celera389,520,423 - 89,538,310 (+)NCBICelera
Cytogenetic Map3q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Cd59
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2311
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2018-10-09
Status: ACTIVE