Gene: Cst3 (cystatin C) Rattus norvegicus
Symbol: Cst3
Name: cystatin C
Description: ENCODES a protein that exhibits peptidase inhibitor activity; protease binding; amyloid-beta binding (ortholog); INVOLVED IN apoptotic process; brain development; cell activation; ASSOCIATED WITH Anemia, Iron-Deficiency; Diabetic Nephropathies; Intracranial Aneurysm; FOUND IN axon; basement membrane; cell projection; INTERACTS WITH 17alpha-ethynylestradiol; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CYSC; cystatin 3; Cystatin C (cysteine proteinase inhibitor); cystatin-3; cystatin-C; MGC105556
Homo sapiens (human) : CST3 (cystatin C)  HGNC  Alliance
Mus musculus (house mouse) : Cst3 (cystatin C)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cst3 (cystatin C)
Pan paniscus (bonobo/pygmy chimpanzee) : CST3 (cystatin C)
Canis lupus familiaris (dog) : LOC607874 (cystatin-C-like)
more info ...
Allele / Splice: Cst3Tn(sb-T2/Bart3)2.172Mcwi   Cst3em1Mcwi   Cst3em3Mcwi  
Genetic Models: F344-Cst3Tn(sb-T2/Bart3)2.172Mcwi SS-Cst3em1Mcwi SS-Cst3em3Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.03143,219,671 - 143,223,544 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03149,628,692 - 149,632,565 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43137,650,903 - 137,654,776 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13137,556,481 - 137,560,243 (-)NCBI
Celera3135,178,032 - 135,181,905 (-)NCBICelera
Cytogenetic Map3q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Cst3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2432
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2018-03-13
Status: ACTIVE